Family physician and endocrinologist coordination as the basis for diabetes care in clinical practice.

Abstract:

BACKGROUND:To estimate the proportion of diabetic patients (DPts) with peripheral vascular disease treated at a primary health care site after an endocrinologist-based intervention, who meet ATP III and Steno targets of metabolic control, as well as to compare the outcome with the results of the patients treated by endocrinologists. METHODS:A controlled, prospective over 30-months period study was conducted in area 7 of Madrid. One hundred twenty six eligible diabetic patients diagnosed as having peripheral vascular disease between January 2003 and June 2004 were included in the study. After a treatment period of three months by the Diabetes team at St Carlos Hospital, 63 patients were randomly assigned to continue their follow up by diabetes team (Group A) and other 63 to be treated by the family physicians (FP) at primary care level with continuous diabetes team coordination (Group B). 57 DPts from Group A and 59 from Group B, completed the 30 months follow-up period. At baseline both groups were similar in age, weight, time from diagnosis and metabolic control. The main outcomes of this study were the proportion of patients meeting ATP III and Steno goals for HbA1c (%), Cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, blood pressure, albumine-to-creatinine excretion ratio (ACR), body mass index (BMI), waist circumference (WC), anti-aggregation treatment and smoking status. RESULTS:At the end of the follow up, no differences were found between the groups. More than 37% of diabetic patients assigned to be treated by FP achieved a HbA1c < 6.5%, more than 50% a ACR < 30 mg/g, and more than 80% reached low risk values for cholesterol, LDL cholesterol, triglycerides, diastolic blood pressure and were anti-aggregated, and 12% remained smokers. In contrast, less than 45% achieved a systolic blood pressure < 130 mm Hg, less than 12% had a BMI < 25 Kg.m-2 (versus 23% in group A; p < 0.05) and 49%/30% (men/women) had a waist circumference of low risk. CONCLUSION:Improvements in metabolic control among diabetic patients with peripheral vascular disease treated at a primary health care setting is possible, reaching similar results to the patients treated at a specialized level. Despite such an improvement, body weight control remains more than poor in both levels, mainly at primary care level. General practitioner and endocrinologist coordination care may be important to enhance diabetes management in primary care settings. TRIAL REGISTRATION:Clinical Trial number ISRCTN75037597.

journal_name

BMC Endocr Disord

journal_title

BMC endocrine disorders

authors

Duran A,Runkle I,Matía P,de Miguel MP,Garrido S,Cervera E,Fernandez MD,Torres P,Lillo T,Martin P,Cabrerizo L,de la Torre NG,Calle JR,Ibarra J,Charro AL,Calle-Pascual AL

doi

10.1186/1472-6823-8-9

subject

Has Abstract

pub_date

2008-07-31 00:00:00

pages

9

issn

1472-6823

pii

1472-6823-8-9

journal_volume

8

pub_type

杂志文章
  • Primary care physicians' practice regarding diabetes mellitus diagnosis, evaluation and management in the West region of Cameroon.

    abstract:BACKGROUND:Primary care physicians (PCPs) are the main providers of diabetes care especially in resource-limited countries which experience extreme shortage of specialists. The present study aimed to evaluate PCPs' approach towards diabetes mellitus (DM) diagnosis, evaluation and management in Cameroon. METHODS:We car...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-015-0016-3

    authors: Jingi AM,Nansseu JR,Noubiap JJ

    更新日期:2015-04-04 00:00:00

  • PCOS without hyperandrogenism is associated with higher plasma Trimethylamine N-oxide levels.

    abstract:BACKGROUND:Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder, and its pathogenesis is still under debate. Trimethylamine-N-oxide (TMAO) is a small, organic compound generated by the gut microbiome with a hypothesized relation to insulin resistance (IR) and low-grade inflammation in PCOS. By compar...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-019-0486-9

    authors: Huang J,Liu L,Chen C,Gao Y

    更新日期:2020-01-06 00:00:00

  • Gene-chip studies of adipogenesis-regulated microRNAs in mouse primary adipocytes and human obesity.

    abstract:BACKGROUND:Adipose tissue abundance relies partly on the factors that regulate adipogenesis, i.e. proliferation and differentiation of adipocytes. While components of the transcriptional program that initiates adipogenesis is well-known, the importance of microRNAs in adipogenesis is less well studied. We thus set out ...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/1472-6823-11-7

    authors: Keller P,Gburcik V,Petrovic N,Gallagher IJ,Nedergaard J,Cannon B,Timmons JA

    更新日期:2011-03-22 00:00:00

  • Fasting in diabetes treatment (FIT) trial: study protocol for a randomised, controlled, assessor-blinded intervention trial on the effects of intermittent use of a fasting-mimicking diet in patients with type 2 diabetes.

    abstract:BACKGROUND:Caloric restriction is an effective way to treat Type 2 diabetes (T2D). However, chronic and severe restriction of food intake is difficult to sustain and is known to promote slower metabolism. Intermittent and frequent fasting can exert similar metabolic effects, but may be even more challenging for most pa...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-020-00576-7

    authors: van den Burg EL,Schoonakker MP,van Peet PG,van den Akker-van Marle ME,Willems van Dijk K,Longo VD,Lamb HJ,Numans ME,Pijl H

    更新日期:2020-06-24 00:00:00

  • Cost effectiveness and value of information analyses of islet cell transplantation in the management of 'unstable' type 1 diabetes mellitus.

    abstract:BACKGROUND:Islet cell transplantation is a method to stabilize type 1 diabetes patients with hypoglycemia unawareness and unstable blood glucose levels by reducing insulin dependency and protecting against severe hypoglycemia through restoring endogenous insulin secretion. This study analyses the current cost-effective...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-016-0097-7

    authors: Wallner K,Shapiro AM,Senior PA,McCabe C

    更新日期:2016-04-09 00:00:00

  • The second wave of the Controlled Antenatal Thyroid Screening (CATS II) study: the cognitive assessment protocol.

    abstract:BACKGROUND:Children whose mothers had low thyroid hormone levels during pregnancy have been reported to have decreased cognitive function. The reported research is part of the follow-on study of the Controlled Antenatal Thyroid Screening Study (CATS I), a randomised controlled trial which investigated the impact of tre...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1186/1472-6823-14-95

    authors: Hales C,Channon S,Taylor PN,Draman MS,Muller I,Lazarus J,Paradice R,Rees A,Shillabeer D,Gregory JW,Dayan CM,Ludgate M

    更新日期:2014-12-12 00:00:00

  • Altered expression of DLG1-AS1 distinguished papillary thyroid carcinoma from benign thyroid nodules.

    abstract:BACKGROUND:Benign thyroid nodules (BTN) are frequently diagnosed as papillary thyroid carcinoma (PTC), leading to unnecessary treatment. We found that plasma lncRNA DLG1-AS1 was upregulated in PTC patients but not in BTN patients and healthy controls. METHODS:In this study DLG1-AS1 and miR-199a-3p in plasma of both PT...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-019-0440-x

    authors: He T,Wang H,Sun J,Wu J,Gong F,Li S,Wang H,Li Y

    更新日期:2019-11-12 00:00:00

  • Lack of association of colonic epithelium telomere length and oxidative DNA damage in Type 2 diabetes under good metabolic control.

    abstract:BACKGROUND:Telomeres are DNA repeat sequences necessary for DNA replication which shorten at cell division at a rate directly related to levels of oxidative stress. Critical telomere shortening predisposes to cell senescence and to epithelial malignancies. Type 2 diabetes is characterised by increased oxidative DNA dam...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/1472-6823-8-12

    authors: Kejariwal D,Stepien KM,Smith T,Kennedy H,Hughes DA,Sampson MJ

    更新日期:2008-10-10 00:00:00

  • Inequalities and factors associated with adherence to diabetes self-care practices amongst patients at two public hospitals in Gauteng, South Africa.

    abstract:BACKGROUND:Self- management is vital to the control of diabetes. This study aims to assess the diabetes self-care behaviours of patients attending two tertiary hospitals in Gauteng, South Africa. The study also seeks to estimate the inequalities in adherence to diabetes self-care practices and associated factors. METH...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-020-0492-y

    authors: Mutyambizi C,Pavlova M,Hongoro C,Groot W

    更新日期:2020-01-28 00:00:00

  • Increased skin autofluorescence of children and adolescents with type 1 diabetes despite a well-controlled HbA1c: results from a cohort study.

    abstract:BACKGROUND:Early identification of children and adolescents with type 1 diabetes at high risk for development of complications is important, as early intervention may prevent further deterioration. Here we investigate the applicability of assessing skin advanced glycation end products (sAGEs) by skin autofluorescence (...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-016-0129-3

    authors: van der Heyden JC,Birnie E,Mul D,Bovenberg S,Veeze HJ,Aanstoot HJ

    更新日期:2016-09-09 00:00:00

  • The effects of cognitive behavioral therapy for insomnia in people with type 2 diabetes mellitus, pilot RCT part II: diabetes health outcomes.

    abstract:BACKGROUND:Previous studies have shown the negative impact of sleep disturbances, specifically insomnia symptoms, on glucose metabolism for people with type 2 diabetes (T2D). People with insomnia symptoms are at risk of poor glycemic control and suboptimal diabetes self-care behavior (DSCB). Investigating the impact of...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-020-00612-6

    authors: Alshehri MM,Alothman SA,Alenazi AM,Rucker JL,Phadnis MA,Miles JM,Siengsukon CF,Kluding PM

    更新日期:2020-09-05 00:00:00

  • Association between sleep disorder and quality of life in patients with type 2 diabetes: a cross-sectional study.

    abstract:BACKGROUND:We investigated the association between sleep symptoms, which cause sleep disorder, and quality of life (QoL) among people with type 2 diabetes (T2D). METHODS:In this cross-sectional study of 342 people with T2D, the Japan National Health and Wellness Survey (NHWS) database 2016 were used. We treated the re...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-020-00579-4

    authors: Hashimoto Y,Sakai R,Ikeda K,Fukui M

    更新日期:2020-06-30 00:00:00

  • Association of thyroid nodules with adiposity: a community-based cross-sectional study in China.

    abstract:BACKGROUND:The association between thyroid nodules and adiposity remains controversial. We performed a cross-sectional, community-based study to examine whether thyroid nodules are associated with overweight and obesity, as defined with body mass index (BMI) and waist circumference. METHODS:The study included 1482 sub...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-018-0232-8

    authors: Song B,Zuo Z,Tan J,Guo J,Teng W,Lu Y,Liu C

    更新日期:2018-01-27 00:00:00

  • Does moxonidine reduce Achilles tendon or musculoskeletal pain in women with polycystic ovarian syndrome? A secondary analysis of a randomised controlled trial.

    abstract:BACKGROUND:Sympathetic activity and insulin resistance have recently been linked with chronic tendon and musculoskeletal pain. Polycystic ovarian syndrome is linked with insulin resistance and increased sympathetic drive and was therefore an appropriate condition to study the effects of modulating sympathetic activity ...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-020-00610-8

    authors: Jewson J,Lambert E,Sari C,Jona E,Shorakae S,Lambert G,Gaida J

    更新日期:2020-08-26 00:00:00

  • Reference intervals for thyroid stimulating hormone and free thyroxine derived from neonates undergoing routine screening for congenital hypothyroidism at a university teaching hospital in Nairobi, Kenya: a cross sectional study.

    abstract:BACKGROUND:In order to accurately interpret neonatal thyroid function tests (TFTs), it is necessary to have population specific reference intervals (RIs) as there is significant variation across different populations possibly due to genetic, environmental or analytical issues. Despite the importance of RIs, globally th...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-016-0107-9

    authors: Omuse G,Kassim A,Kiigu F,Hussain SR,Limbe M

    更新日期:2016-05-23 00:00:00

  • Cardiac valvular abnormalities associated with use and cumulative exposure of cabergoline for hyperprolactinemia: the CATCH study.

    abstract:BACKGROUND:Whether lower dose cabergoline therapy for hyperprolactinemia increases risk of valvular dysfunction remains controversial. We examined valvular abnormalities among asymptomatic adults with hyperprolactinemia treated with dopamine agonists. METHODS:This cross-sectional study was conducted among adults recei...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-020-0507-8

    authors: Budayr A,Tan TC,Lo JC,Zaroff JG,Tabada GH,Yang J,Go AS

    更新日期:2020-02-19 00:00:00

  • Non-invasive detection of microvascular changes in a paediatric and adolescent population with type 1 diabetes: a pilot cross-sectional study.

    abstract:BACKGROUND:The detection of microvascular damage in type 1 diabetes is difficult and traditional investigations do not detect changes until they are well established. The purpose of this study was to investigate the combined ability of nailfold capillaroscopy, laser Doppler flowmetry, retinal vessel analysis and 24-hr ...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/1472-6823-13-41

    authors: Hosking SP,Bhatia R,Crock PA,Wright I,Squance ML,Reeves G

    更新日期:2013-10-05 00:00:00

  • No increased risk of glucose metabolism disorders in adults with growth hormone deficiency undergoing long-term treatment with biosimilar somatropin (Omnitrope®): data from an observational, longitudinal study.

    abstract:BACKGROUND:To evaluate the impact of treatment with recombinant human growth hormone (rhGH; Omnitrope®) on the risk of diabetes mellitus in adults with growth hormone deficiency (GHD), using data from the ongoing PATRO Adults post-marketing surveillance study. METHODS:PATRO Adults is an ongoing post-marketing surveill...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-019-0464-2

    authors: Beck-Peccoz P,Höybye C,Murray RD,Simsek S,Zabransky M,Zouater H,Stalla G

    更新日期:2019-12-11 00:00:00

  • Spontaneous adrenocorticotropic hormone (ACTH) normalisation due to tumour regression induced by metyrapone in a patient with ectopic ACTH syndrome: case report and literature review.

    abstract:BACKGROUND:Ectopic adrenocorticotropic hormone (ACTH) syndrome (EAS) is caused by tumours releasing ACTH. Ectopic ACTH-producing tumour regression is rarely induced using steroidogenesis inhibitors. We presented a case of EAS in which ACTH production by a lung tumour was reduced by metyrapone (MTP) and also reviewed pr...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-018-0246-2

    authors: Iwayama H,Hirase S,Nomura Y,Ito T,Morita H,Otake K,Okumura A,Takagi J

    更新日期:2018-03-27 00:00:00

  • Implication of intracellular localization of transcriptional repressor PLZF in thyroid neoplasms.

    abstract:BACKGROUND:Promyelocytic leukaemia zinc finger (PLZF) is a transcriptional repressor that was originally isolated from a patient with promyelocytic leukaemia. PLZF also affects key elements for cell cycle progression, such as cyclin A, and can affect the tumourigenicity of various cancers. Thus far, the behaviour of PL...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/1472-6823-14-52

    authors: Matsuzawa K,Izawa S,Ohkura T,Ohkura H,Ishiguro K,Yoshida A,Takiyama Y,Haneda M,Shigemasa C,Yamamoto K,Taniguchi S

    更新日期:2014-07-03 00:00:00

  • Role of enteral nutrition in nonthyroidal illness syndrome: a retrospective observational study.

    abstract:BACKGROUND:The nonthyroidal illness syndrome (NTIS) is prevalent among patients with enterocutaneous fistula and is associated with poor outcomes. The present study aimed to explore the role of enteral nutrition (EN) therapy on thyroid function among patients with enterocutaneous fistula and NTIS. METHODS:We conducted...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-015-0061-y

    authors: Li R,Ren J,Wu Q,Wang G,Wu X,Chen J,Li G,Hong Z,Ren H,Zhao Y,Li J

    更新日期:2015-11-04 00:00:00

  • Prolactinomas, Cushing's disease and acromegaly: debating the role of medical therapy for secretory pituitary adenomas.

    abstract:: Pituitary adenomas are associated with a variety of clinical manifestations resulting from excessive hormone secretion and tumor mass effects, and require a multidisciplinary management approach. This article discusses the treatment modalities for the management of patients with a prolactinoma, Cushing's disease and ...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/1472-6823-10-10

    authors: Biller BM,Colao A,Petersenn S,Bonert VS,Boscaro M

    更新日期:2010-05-17 00:00:00

  • Overtime trend of thyroid hormones and thyroid autoimmunity and ovarian reserve: a longitudinal population study with a 12-year follow up.

    abstract:BACKGROUND:Ovarian reserve, vital for reproductive function, can be adversely affected by thyroid diseases. Despite alternations of thyroid hormones with ageing, data on interactions between the overtime trend of thyroid functions and ovarian reserve status has rarely been reported. We aimed to examine the overtime tre...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-019-0370-7

    authors: Bahri S,Tehrani FR,Amouzgar A,Rahmati M,Tohidi M,Vasheghani M,Azizi F

    更新日期:2019-05-07 00:00:00

  • Risk assessment for foot ulcers among Tunisian subjects with diabetes: a cross sectional outpatient study.

    abstract:BACKGROUND:Diabetic foot is an underestimated and redoubtable diabetes complication. The aims of our study were to assess diabetic foot ulcer risk factors according to International Working Group on the Diabetic Foot (IWGDF) classification, stratify patients into risk categories and identify factors associated with hig...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-020-00608-2

    authors: Zantour B,Bouchareb S,El Ati Z,Boubaker F,Alaya W,Kossomtini W,Sfar MH

    更新日期:2020-08-24 00:00:00

  • Severe hypoglycemia symptoms, antecedent behaviors, immediate consequences and association with glycemia medication usage: Secondary analysis of the ACCORD clinical trial data.

    abstract:BACKGROUND:Hypoglycemia is a common complication of diabetes treatment. This paper describes symptoms, predecessors, consequences and medications associated with the first episode of severe hypoglycemia among ACCORD participants with type 2 diabetes, and compares these between intensive (Int: goal A1C <6.0%) and standa...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/1472-6823-12-5

    authors: Bonds DE,Miller ME,Dudl J,Feinglos M,Ismail-Beigi F,Malozowski S,Seaquist E,Simmons DL,Sood A

    更新日期:2012-05-30 00:00:00

  • Current concepts in parathyroid carcinoma: a single Centre experience.

    abstract:BACKGROUND:Parathyroid carcinoma is a rare neoplasm that may present sporadically or in the context of a genetic syndrome. Diagnosis and management are challenging due to the lack of clinical and pathological features that may reliably distinguish malignant from benign disease. METHODS:From January 2013 to December 20...

    journal_title:BMC endocrine disorders

    pub_type: 临床试验,杂志文章

    doi:10.1186/s12902-019-0368-1

    authors: Ferraro V,Sgaramella LI,Di Meo G,Prete FP,Logoluso F,Minerva F,Noviello M,Renzulli G,Gurrado A,Testini M

    更新日期:2019-05-29 00:00:00

  • Urinary iodine in early pregnancy is associated with subclinical hypothyroidism in Tianjin, China: an observational study.

    abstract:BACKGROUND:Subclinical hypothyroidism (SH) is associated with adverse obstetric outcomes and neurodevelopment disorders. Both iodine deficiency and excess are associated with SH; however, few data regarding iodine nutrition status of pregnant women with SH are available. This study aimed to clarify whether iodine defic...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-017-0162-x

    authors: Wang K,Zhang J,Li F,Zhang W,Wang H,Ding L,Liu Y,Lin L,Zhang S,Zhu M

    更新日期:2017-02-17 00:00:00

  • Poor sleep quality is associated with increased arterial stiffness in Japanese patients with type 2 diabetes mellitus.

    abstract:BACKGROUND:While poor sleep quality can worsen cardiovascular risk factors such as glucose and lipid profiles in patients with type 2 diabetes mellitus (T2DM), the relationship between sleep quality and atherosclerosis remains largely unknown. The aim of this study was to examine this relationship. METHODS:The study p...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-015-0026-1

    authors: Osonoi Y,Mita T,Osonoi T,Saito M,Tamasawa A,Nakayama S,Someya Y,Ishida H,Kanazawa A,Gosho M,Fujitani Y,Watada H

    更新日期:2015-06-18 00:00:00

  • Mobile health in the management of type 1 diabetes: a systematic review and meta-analysis.

    abstract:BACKGROUND:As an insulin-dependent disease, type 1 diabetes requires paying close attention to the glycemic control. Studies have shown that mobile health (mHealth) can improve the management of chronic diseases. However, the effectiveness of mHealth in controlling the glycemic control remains uncertain. The objective ...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章,meta分析

    doi:10.1186/s12902-019-0347-6

    authors: Wang X,Shu W,Du J,Du M,Wang P,Xue M,Zheng H,Jiang Y,Yin S,Liang D,Wang R,Hou L

    更新日期:2019-02-13 00:00:00

  • Differential diagnostic value of bilateral inferior Petrosal sinus sampling (BIPSS) in ACTH-dependent Cushing syndrome: a systematic review and Meta-analysis.

    abstract:BACKGROUND:Previous studies have shown inconsistent results about the usefulness of bilateral inferior petrosal sinus sampling (BIPSS) in differential diagnosis of adrenocorticotropic hormone (ACTH)-dependent Cushing syndrome. This meta-analysis evaluated the diagnostic value of BIPSS via the published literature. MET...

    journal_title:BMC endocrine disorders

    pub_type: 杂志文章

    doi:10.1186/s12902-020-00623-3

    authors: Wang H,Ba Y,Xing Q,Cai RC

    更新日期:2020-09-17 00:00:00