Lack of association of colonic epithelium telomere length and oxidative DNA damage in Type 2 diabetes under good metabolic control.

abstract：BACKGROUND:There have only been a few reports about use of dipeptidyl peptidase 4 (DPP-4) inhibitors in elderly patients with type 2 diabetes mellitus (T2DM), suggesting that the safety of these agents has not been sufficiently demonstrated. We performed a comparative review of the efficacy and safety of sitagliptin fo...

journal_title：BMC endocrine disorders

authors： Umezawa S,Kubota A,Maeda H,Kanamori A,Matoba K,Jin Y,Minagawa F,Obana M,Iemitsu K,Ito S,Amamiya H,Kaneshiro M,Takai M,Kaneshige H,Hoshino K,Ishikawa M,Minami N,Takuma T,Sasai N,Aoyagi S,Kawata T,Mokubo A,Miyai

更新日期：2015-07-03 00:00:00

abstract：BACKGROUND:Insulin resistance and diabetes are associated with increased oxidative stress and impairment of cellular defence systems. Our purpose was to investigate the interaction between glucose metabolism, antioxidative capacity and heat shock protein (HSP) defence in different skeletal muscle phenotypes among middl...

journal_title：BMC endocrine disorders

authors： Venojärvi M,Aunola S,Puhke R,Marniemi J,Hämäläinen H,Halonen JP,Lindström J,Rastas M,Hällsten K,Nuutila P,Hänninen O,Atalay M

更新日期：2008-03-27 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the association between blood manganese levels and the prevalence of chronic diseases in the Korean population. METHODS:This was a cross-sectional study based on the Korean National Health and Nutrition Examination Survey (KNAHNES). The study included 3996 participa...

journal_title：BMC endocrine disorders

authors： Koh ES,Kim SJ,Yoon HE,Chung JH,Chung S,Park CW,Chang YS,Shin SJ

更新日期：2014-03-08 00:00:00

abstract：BACKGROUND:Seminomas have been rarely associated with malignant hypercalcemia. The responsible mechanism of hypercalcemia in this setting has been described to be secondary to 1,25-dihydroxyvitamin D secretion. The relationship with PTHrP has not been determined or studied.The aim of this study is to describe and discu...

journal_title：BMC endocrine disorders

authors： Rodríguez-Gutiérrez R,Zapata-Rivera MA,Quintanilla-Flores DL,Camara-Lemarroy CR,Lavalle-Gonzalez FJ,González-González JG,Villarreal-Pérez JZ

更新日期：2014-04-10 00:00:00

abstract：BACKGROUND:Thyrotoxicosis is often caused by destructive thyroiditis (DT) or Graves' disease (GD), and a prompt and accurate differential diagnosis for thyrotoxicosis is needed as management strategy differs. A meta-analysis of published literature was performed to evaluate the diagnostic accuracy for differentiating G...

journal_title：BMC endocrine disorders

authors： Peng X,Wu S,Bie C,Tang H,Xiong Z,Tang S

更新日期：2019-06-06 00:00:00

abstract：BACKGROUND:11 patients were referred to our Molecular Genetics Department at the Royal Devon and Exeter Hospital between 2000-2012 with a physician's diagnosis of remitting diabetes. Our aim was to identify patients with remitting diabetes whose clinical presentation is not explained by any known aetiology of diabetes....

journal_title：BMC endocrine disorders

authors： Babiker T,Chakera AJ,Shepherd M,Hattersley AT

更新日期：2014-06-09 00:00:00

abstract：UNLABELLED: BACKGROUND:Severe hypoglycaemia (SH) is one of the most feared complications of type 1 diabetes (T1DM) with a reported prevalence of nearly 40%. In randomized trials of Multiple Daily Injections (MDI) and Continuous Subcutaneous Insulin Infusion (CSII) therapy there is a possible benefit of CSII in reducin...

journal_title：BMC endocrine disorders

authors： Little S,Chadwick T,Choudhary P,Brennand C,Stickland J,Barendse S,Olateju T,Leelarathna L,Walkinshaw E,Tan HK,Marshall SM,Thomas RM,Heller S,Evans M,Kerr D,Flanagan D,Speight J,Shaw JA

更新日期：2012-12-13 00:00:00

abstract：BACKGROUND:Alogliptin is a new dipeptidyl peptidase (DPP-4) inhibitor, which is under investigation for treatment of type 2 diabetes either alone or in combination with other antidiabetic drugs. The aim of this meta-analysis was to assess the efficacy and tolerability of alogliptin in patients with type 2 diabetes. ME...

journal_title：BMC endocrine disorders

authors： Berhan A,Berhan Y

更新日期：2013-03-01 00:00:00

abstract：UNLABELLED: BACKGROUND:The use of chromium supplements is widespread for the prevention and treatment of diabetes mellitus but there are conflicting reports on efficacy, possibly reflecting discrepant effects across different populations. In the present studies, we test the hypothesis that chromium supplementation rai...

journal_title：BMC endocrine disorders

authors： Masharani U,Gjerde C,McCoy S,Maddux BA,Hessler D,Goldfine ID,Youngren JF

更新日期：2012-11-30 00:00:00

abstract：BACKGROUND:Autoimmune hypophysitis is a rare disease characterized by the infiltration of lymphocytic cells into the pituitary gland. 18F-fluorodeoxyglucose (FDG) and 18F-2-fluorodeoxy sorbitol (FDS) positron emission tomography (PET) are well-established and emerging techniques, respectively, which may aid in the diag...

journal_title：BMC endocrine disorders

authors： Kong Z,Wang Y,Ma W,Cheng X

更新日期：2020-06-09 00:00:00

abstract：BACKGROUND:Diabetes mellitus (DM) is a global health care problem that can impose a substantial economic burden. Diabetic peripheral neuropathy (DPN) is a common microvascular complication of DM that increases the potential for morbidity and disability due to ulceration and amputation. Though there is a significant amo...

journal_title：BMC endocrine disorders

authors： Shiferaw WS,Akalu TY,Work Y,Aynalem YA

更新日期：2020-04-15 00:00:00

abstract：BACKGROUND:Most studies on cortisol have focused on smaller, selected samples. We therefore aimed to sex-specifically study the diurnal cortisol pattern and explore its association with abdominal obesity in a large unselected population. METHODS:In 2001-2004, 1811 men and women (30-75 years) were randomly selected fro...

journal_title：BMC endocrine disorders

authors： Larsson CA,Gullberg B,Råstam L,Lindblad U

更新日期：2009-06-21 00:00:00

abstract：BACKGROUND:Type 2 diabetes is a common and costly illness, associated with significant morbidity and mortality. Despite this, there is relatively little information on the 'real-world' medication utilization patterns for patients with type 2 diabetes initiating exenatide BID or glargine. The objective of this study was...

journal_title：BMC endocrine disorders

authors： Pawaskar M,Bonafede M,Johnson B,Fowler R,Lenhart G,Hoogwerf B

更新日期：2013-06-22 00:00:00

abstract：BACKGROUND:Benign thyroid nodules (BTN) are frequently diagnosed as papillary thyroid carcinoma (PTC), leading to unnecessary treatment. We found that plasma lncRNA DLG1-AS1 was upregulated in PTC patients but not in BTN patients and healthy controls. METHODS:In this study DLG1-AS1 and miR-199a-3p in plasma of both PT...

journal_title：BMC endocrine disorders

authors： He T,Wang H,Sun J,Wu J,Gong F,Li S,Wang H,Li Y

更新日期：2019-11-12 00:00:00

abstract：BACKGROUND:Mexican Americans are at an increased risk of both thyroid dysfunction and metabolic syndrome (MS). Thus it is conceivable that some components of the MS may be associated with the risk of thyroid dysfunction in these individuals. Our objective was to investigate and replicate the potential association of MS...

journal_title：BMC endocrine disorders

authors： Mamtani M,Kulkarni H,Dyer TD,Almasy L,Mahaney MC,Duggirala R,Comuzzie AG,Samollow PB,Blangero J,Curran JE

更新日期：2014-06-10 00:00:00

abstract：BACKGROUND:Insufficient vitamin D status and increased renin-angiotensin system (RAS) activity have been associated with renal-vascular disease and nephropathy in diabetes. Accumulating evidence indicates that vitamin D receptor (VDR) activation lowers unfavorable RAS activity; however, more human intervention studies ...

journal_title：BMC endocrine disorders

authors： Brown JM,Secinaro K,Williams JS,Vaidya A

更新日期：2013-08-23 00:00:00

abstract：BACKGROUND:The burden of non-communicable diseases is growing rapidly in low- and middle-income countries. Research suggests that health interventions that aim to improve patient self-management and empower patients to care actively for their disease will improve health outcomes over the long-term. There is, however, a...

journal_title：BMC endocrine disorders

authors： Abrahams N,Gilson L,Levitt NS,Dave JA

更新日期：2019-12-05 00:00:00

abstract：BACKGROUND:The prevalence of type 2 diabetes mellitus (T2DM) is expected to increase from 7.7% in 2017 to 8.4% in 2045 worldwide. Diabetes complications contribute to morbidity and mortality. To evaluate whether the diabetes complications severity index (DCSI) was associated with increased risks of mortality and hospit...

journal_title：BMC endocrine disorders

authors： Yoo H,Choo E,Lee S

更新日期：2020-08-10 00:00:00

abstract：BACKGROUND:Most of the patients with type 1 and V hyperlipoproteinemia (HLP) present with symptoms and signs of acute pancreatitis due to marked elevation of triglycerides, but this baby presented with a chest infection, which was later diagnosed as type V HLP on laboratory workup. CASE PRESENTATION:We report a case o...

journal_title：BMC endocrine disorders

authors： Dildar S,Shamsi TS

更新日期：2020-02-11 00:00:00

abstract：BACKGROUND:We report a novel mutation within the StAR gene, causing congenital adrenal hyperplasia, with the so far unreported association with heterochromia iridis. CASE PRESENTATION:In a now 15-year-old girl (born at 41 + 6 weeks of gestation) adrenal failure was diagnosed in the neonatal period based on the clinica...

journal_title：BMC endocrine disorders

authors： Splittstösser V,Schreiner F,Gohlke B,Welzel M,Holterhus PM,Woelfle J

更新日期：2019-10-30 00:00:00

abstract：BACKGROUND:Whether lower dose cabergoline therapy for hyperprolactinemia increases risk of valvular dysfunction remains controversial. We examined valvular abnormalities among asymptomatic adults with hyperprolactinemia treated with dopamine agonists. METHODS:This cross-sectional study was conducted among adults recei...

journal_title：BMC endocrine disorders

authors： Budayr A,Tan TC,Lo JC,Zaroff JG,Tabada GH,Yang J,Go AS

更新日期：2020-02-19 00:00:00

abstract：:Oxytocin (OT) emerges as a drug for the treatment of diabetes and obesity. The entire OT system is synthesized in the rat and human heart. The direct myocardial infusion with OT into an ischemic or failing heart has the potential to elicit a variety of cardioprotective effects. OT treatment attenuates cardiomyocyte (C...

journal_title：BMC endocrine disorders

authors： Jankowski M,Broderick TL,Gutkowska J

更新日期：2016-06-07 00:00:00

abstract：BACKGROUND:Limited real-world data are currently available on hypoglycemia in diabetes patients. The International Operations Hypoglycemia Assessment Tool (IO HAT) study was designed to estimate hypoglycemia in insulin-treated type I (T1DM) and type II (T2DM) diabetes mellitus patients from 9 countries. The data from T...

journal_title：BMC endocrine disorders

authors： Emral R,Tetiker T,Sahin I,Sari R,Kaya A,Yetkin İ,Cil SU,Tütüncü NB,IO HAT investigator group.

更新日期：2018-02-13 00:00:00

abstract：BACKGROUND:Pituitary metastasis is a rare condition with a poor prognosis. Very few patients with pituitary metastasis are symptomatic. It is often associated with presence of co-existing metastases to other organs. Isolated pituitary metastasis as the first presentation of primary malignancy is uncommon. CASE PRESENT...

journal_title：BMC endocrine disorders

authors： Sirinvaravong S,Vibhatavata P,Chunharojrith P,Cheunsuchon P,Sriussadaporn S

更新日期：2019-10-29 00:00:00

abstract：BACKGROUND:Early identification of children and adolescents with type 1 diabetes at high risk for development of complications is important, as early intervention may prevent further deterioration. Here we investigate the applicability of assessing skin advanced glycation end products (sAGEs) by skin autofluorescence (...

journal_title：BMC endocrine disorders

authors： van der Heyden JC,Birnie E,Mul D,Bovenberg S,Veeze HJ,Aanstoot HJ

更新日期：2016-09-09 00:00:00

abstract：BACKGROUND:Subclinical hypothyroidism (SH) is associated with adverse obstetric outcomes and neurodevelopment disorders. Both iodine deficiency and excess are associated with SH; however, few data regarding iodine nutrition status of pregnant women with SH are available. This study aimed to clarify whether iodine defic...

journal_title：BMC endocrine disorders

authors： Wang K,Zhang J,Li F,Zhang W,Wang H,Ding L,Liu Y,Lin L,Zhang S,Zhu M

更新日期：2017-02-17 00:00:00

abstract：BACGROUND:To assess the contribution of macroprolactin to high serum prolactin levels and their association with thyroid status and thyroid autoimmunity during pregnancy. METHODS:138 pregnant women who suspected of having thyroid dysfunction were studied and divided into three groups according to the thyroid status; g...

journal_title：BMC endocrine disorders

authors： Guclu M,Cander S,Kiyici S,Vatansever E,Hacihasanoğlu AB,Kisakol G

更新日期：2015-06-20 00:00:00

abstract：BACKGROUND:Diabetes is a major public health problem worldwide. This problem is particularly relevant to the elderly. The prevalence of each condition increase with age. The present study aimed to determine the prevalence of Diabetes Mellitus (DM) among elderly; we also examined socio-economic factors and life style th...

journal_title：BMC endocrine disorders

authors： Hammami S,Mehri S,Hajem S,Koubaa N,Souid H,Hammami M

更新日期：2012-08-16 00:00:00

abstract：BACKGROUND:Previous studies have shown the negative impact of sleep disturbances, specifically insomnia symptoms, on glucose metabolism for people with type 2 diabetes (T2D). People with insomnia symptoms are at risk of poor glycemic control and suboptimal diabetes self-care behavior (DSCB). Investigating the impact of...

journal_title：BMC endocrine disorders

authors： Alshehri MM,Alothman SA,Alenazi AM,Rucker JL,Phadnis MA,Miles JM,Siengsukon CF,Kluding PM

更新日期：2020-09-05 00:00:00

abstract：BACKGROUND:Lifestyle modification targeting weight management is the first-line treatment for women with Polycystic Ovary Syndrome (PCOS) regardless of presenting symptoms. Women with PCOS are more likely to gain more weight compared with women without PCOS, which may be related to barriers in engaging in lifestyle mod...

journal_title：BMC endocrine disorders

authors： Lim S,Smith CA,Costello MF,MacMillan F,Moran L,Ee C

更新日期：2019-10-23 00:00:00