Efficacy of alogliptin in type 2 diabetes treatment: a meta-analysis of randomized double-blind controlled studies.

abstract：BACKGROUND:Children whose mothers had low thyroid hormone levels during pregnancy have been reported to have decreased cognitive function. The reported research is part of the follow-on study of the Controlled Antenatal Thyroid Screening Study (CATS I), a randomised controlled trial which investigated the impact of tre...

journal_title：BMC endocrine disorders

authors： Hales C,Channon S,Taylor PN,Draman MS,Muller I,Lazarus J,Paradice R,Rees A,Shillabeer D,Gregory JW,Dayan CM,Ludgate M

更新日期：2014-12-12 00:00:00

abstract：BACKGROUND:Sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) proteins have an important role in counteracting oxidative stress. Although diabetes and hypothyroidism (HT) are both characterized by oxidative stress, the mechanisms are not fully understood. This study investigated the effects of type 1 diabetes (T1D), type 2 diabet...

journal_title：BMC endocrine disorders

authors： Al-Khaldi A,Sultan S

更新日期：2019-02-08 00:00:00

abstract：BACKGROUND:Whether lower dose cabergoline therapy for hyperprolactinemia increases risk of valvular dysfunction remains controversial. We examined valvular abnormalities among asymptomatic adults with hyperprolactinemia treated with dopamine agonists. METHODS:This cross-sectional study was conducted among adults recei...

journal_title：BMC endocrine disorders

authors： Budayr A,Tan TC,Lo JC,Zaroff JG,Tabada GH,Yang J,Go AS

更新日期：2020-02-19 00:00:00

abstract：AIM:To assess the factors associated with antihyperglycaemic medication initiation in UK patients with newly diagnosed type 2 diabetes. METHODS:In a retrospective cohort study, patients with newly diagnosed type 2 diabetes were identified during the index period of 2003-2005. Eligible patients were ≥ 30 years old at t...

journal_title：BMC endocrine disorders

authors： Sinclair AJ,Alexander CM,Davies MJ,Zhao C,Mavros P

更新日期：2012-03-07 00:00:00

abstract：BACKGROUND:Primary hyperparathyroidism is a rare condition of disease which can seldomly present as giant retrotrhyroideal cysts, complicating the localization of the adenoma to resect. CASE PRESENTATION:A 56-year old female presented with hypercalcaemia of 3.38 mmol/L (2.2-2.65 mmol/L) and a history of breast cancer....

journal_title：BMC endocrine disorders

authors： Werner C,Lupp A,Mtuka-Pardon G,Kloos C,Wolf G,Aschenbach R,Biermann A,Freesmeyer M,Seifert P

更新日期：2020-04-20 00:00:00

abstract：BACKGROUND:The pathophysiology of type2 diabetes involves both insulin resistance and poor beta cell function. Studies have been done in several populations to assess the relative importance of these mechanisms in individual patients. In our environment studies to assess beta cell function have been done with glucagon ...

journal_title：BMC endocrine disorders

authors： Young EE,Chinenye S,Unachukwu CN

更新日期：2012-06-27 00:00:00

abstract：BACKGROUND:Non-thyroidal illness syndrome (NTIS) is a characteristic functional constellation of thyrotropic feedback control that frequently occurs in critically ill patients. Although this condition is associated with significantly increased morbidity and mortality, there is still controversy on whether NTIS is cause...

journal_title：BMC endocrine disorders

authors： Dietrich JW,Stachon A,Antic B,Klein HH,Hering S

更新日期：2008-10-13 00:00:00

abstract：BACKGROUND:Diabetic foot is an underestimated and redoubtable diabetes complication. The aims of our study were to assess diabetic foot ulcer risk factors according to International Working Group on the Diabetic Foot (IWGDF) classification, stratify patients into risk categories and identify factors associated with hig...

journal_title：BMC endocrine disorders

authors： Zantour B,Bouchareb S,El Ati Z,Boubaker F,Alaya W,Kossomtini W,Sfar MH

更新日期：2020-08-24 00:00:00

abstract：BACKGROUND:Hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome is a rare autosomal dominant disorder caused by mutations in the zinc finger transcription factor gene, GATA3. GATA3 has 2 zinc finger domains, which play an important role in the increase in target gene transcription activity. CASE PRESENTATI...

journal_title：BMC endocrine disorders

authors： Okawa T,Yoshida M,Usui T,Kudou T,Iwasaki Y,Fukuoka K,Takahashi N,Uehara Y,Oiso Y

更新日期：2015-10-30 00:00:00

abstract：BACKGROUND:Limited real-world data are currently available on hypoglycemia in diabetes patients. The International Operations Hypoglycemia Assessment Tool (IO HAT) study was designed to estimate hypoglycemia in insulin-treated type I (T1DM) and type II (T2DM) diabetes mellitus patients from 9 countries. The data from T...

journal_title：BMC endocrine disorders

authors： Emral R,Tetiker T,Sahin I,Sari R,Kaya A,Yetkin İ,Cil SU,Tütüncü NB,IO HAT investigator group.

更新日期：2018-02-13 00:00:00

abstract：BACKGROUND:Iodine deficiency affects nearly 1.9 billion people worldwide, but it can be prevented by salt iodization. This cross-sectional survey assessed current iodine status, iodized salt coverage and risk factors for goitre among schoolchildren in South Tajikistan. METHODS:Ten primary schools in four districts in ...

journal_title：BMC endocrine disorders

authors： Matthys B,Davlatmamadova M,Karimova G,Jean-Richard V,Zimmermann MB,Wyss K

更新日期：2013-11-02 00:00:00

abstract：BACKGROUND:We aimed to explore metabolite biomarkers that could be used to identify pre-diabetes and type 2 diabetes mellitus (T2DM) using systematic review and meta-analysis. METHODS:Four databases, the Cochrane Library, EMBASE, PubMed and Scopus were selected. A random effect model and a fixed effect model were appl...

journal_title：BMC endocrine disorders

authors： Long J,Yang Z,Wang L,Han Y,Peng C,Yan C,Yan D

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:Early identification of children and adolescents with type 1 diabetes at high risk for development of complications is important, as early intervention may prevent further deterioration. Here we investigate the applicability of assessing skin advanced glycation end products (sAGEs) by skin autofluorescence (...

journal_title：BMC endocrine disorders

authors： van der Heyden JC,Birnie E,Mul D,Bovenberg S,Veeze HJ,Aanstoot HJ

更新日期：2016-09-09 00:00:00

abstract：BACKGROUND:Lifestyle modification targeting weight management is the first-line treatment for women with Polycystic Ovary Syndrome (PCOS) regardless of presenting symptoms. Women with PCOS are more likely to gain more weight compared with women without PCOS, which may be related to barriers in engaging in lifestyle mod...

journal_title：BMC endocrine disorders

authors： Lim S,Smith CA,Costello MF,MacMillan F,Moran L,Ee C

更新日期：2019-10-23 00:00:00

abstract：BACKGROUND:Islet cell transplantation is a method to stabilize type 1 diabetes patients with hypoglycemia unawareness and unstable blood glucose levels by reducing insulin dependency and protecting against severe hypoglycemia through restoring endogenous insulin secretion. This study analyses the current cost-effective...

journal_title：BMC endocrine disorders

authors： Wallner K,Shapiro AM,Senior PA,McCabe C

更新日期：2016-04-09 00:00:00

abstract：BACKGROUND:Benign thyroid nodules (BTN) are frequently diagnosed as papillary thyroid carcinoma (PTC), leading to unnecessary treatment. We found that plasma lncRNA DLG1-AS1 was upregulated in PTC patients but not in BTN patients and healthy controls. METHODS:In this study DLG1-AS1 and miR-199a-3p in plasma of both PT...

journal_title：BMC endocrine disorders

authors： He T,Wang H,Sun J,Wu J,Gong F,Li S,Wang H,Li Y

更新日期：2019-11-12 00:00:00

abstract：BACKGROUND:Telomeres are DNA repeat sequences necessary for DNA replication which shorten at cell division at a rate directly related to levels of oxidative stress. Critical telomere shortening predisposes to cell senescence and to epithelial malignancies. Type 2 diabetes is characterised by increased oxidative DNA dam...

journal_title：BMC endocrine disorders

authors： Kejariwal D,Stepien KM,Smith T,Kennedy H,Hughes DA,Sampson MJ

更新日期：2008-10-10 00:00:00

abstract：BACKGROUND:Vitamin D deficiency is pandemic while resources available to measure 25-hydroxyvitamin D (25OHD) are limited. The present study aimed to verify whether sun exposure measured by a structured questionnaire could predict serum 25OHD concentrations in healthy Caucasian individuals living in a tropical area. ME...

journal_title：BMC endocrine disorders

authors： Bittar FB,Castro CHM,Szejnfeld VL

更新日期：2018-07-03 00:00:00

abstract：BACKGROUND:Insulin and insulin-like growth factor (IGF)-1 coupled with growth hormone helps control timing of sexual maturation. Mutations and variants in multiple genes are associated with development or reduced risk of central precocious puberty (CPP). METHODS:We assessed single nucleotide polymorphisms (SNPs) in th...

journal_title：BMC endocrine disorders

authors： Chang HP,Yang SF,Wang SL,Su PH

更新日期：2018-09-19 00:00:00

abstract：BACKGROUND:We report a novel mutation within the StAR gene, causing congenital adrenal hyperplasia, with the so far unreported association with heterochromia iridis. CASE PRESENTATION:In a now 15-year-old girl (born at 41 + 6 weeks of gestation) adrenal failure was diagnosed in the neonatal period based on the clinica...

journal_title：BMC endocrine disorders

authors： Splittstösser V,Schreiner F,Gohlke B,Welzel M,Holterhus PM,Woelfle J

更新日期：2019-10-30 00:00:00

abstract：:BACKGROUND: The possible participation of endogenous islet catecholamines (CAs) in the control of insulin secretion was tested. METHODS: Glucose-induced insulin secretion was measured in the presence of 3-Iodo-L-Tyrosine (MIT), a specific inhibitor of tyrosine-hydroxylase activity, in fresh and precultured islets isol...

journal_title：BMC endocrine disorders

authors： Borelli MI,Gagliardino JJ

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Type 2 diabetes is a common and costly illness, associated with significant morbidity and mortality. Despite this, there is relatively little information on the 'real-world' medication utilization patterns for patients with type 2 diabetes initiating exenatide BID or glargine. The objective of this study was...

journal_title：BMC endocrine disorders

authors： Pawaskar M,Bonafede M,Johnson B,Fowler R,Lenhart G,Hoogwerf B

更新日期：2013-06-22 00:00:00

abstract：: Pituitary adenomas are associated with a variety of clinical manifestations resulting from excessive hormone secretion and tumor mass effects, and require a multidisciplinary management approach. This article discusses the treatment modalities for the management of patients with a prolactinoma, Cushing's disease and ...

journal_title：BMC endocrine disorders

authors： Biller BM,Colao A,Petersenn S,Bonert VS,Boscaro M

更新日期：2010-05-17 00:00:00

abstract：BACKGROUND:Mexican Americans are at an increased risk of both thyroid dysfunction and metabolic syndrome (MS). Thus it is conceivable that some components of the MS may be associated with the risk of thyroid dysfunction in these individuals. Our objective was to investigate and replicate the potential association of MS...

journal_title：BMC endocrine disorders

authors： Mamtani M,Kulkarni H,Dyer TD,Almasy L,Mahaney MC,Duggirala R,Comuzzie AG,Samollow PB,Blangero J,Curran JE

更新日期：2014-06-10 00:00:00

abstract：BACKGROUND:Several studies have shown that normal weight with central obesity (NWCO) is associated with cardiovascular disease risk factors such as hypertension, dyslipidemia and diabetes. However, the relationship between NWCO and hyperuricemia has not been studied in detail. METHODS:We investigated the association b...

journal_title：BMC endocrine disorders

authors： Shirasawa T,Ochiai H,Yoshimoto T,Nagahama S,Watanabe A,Yoshida R,Kokaze A

更新日期：2020-01-06 00:00:00

abstract：BACKGROUND:Pituitary disorders following pregnancy are an important yet under reported clinical entity in the developing world. Conversely, post partum panhypopituitarism has a more devastating impact on women in such settings due to high fertility rates, poor obstetric care and scarcity of diagnostic and therapeutic r...

journal_title：BMC endocrine disorders

authors： Sheriff FG,Howlett WP,Kilonzo KG

更新日期：2012-07-10 00:00:00

abstract：BACKGROUND:Insulin autoimmune syndrome (IAS) is a rare cause of hypoglycemia and is characterized by the presence of insulin autoantibodies. Patients with IAS usually complain of hypoglycemia without any previous insulin received. Glucocorticoids and immunosuppressants are used to treat IAS. CASE PRESENTATION:We repor...

journal_title：BMC endocrine disorders

authors： Shen Y,Song X,Ren Y

更新日期：2019-12-28 00:00:00

abstract：BACKGROUND:Insulin resistance and diabetes are associated with increased oxidative stress and impairment of cellular defence systems. Our purpose was to investigate the interaction between glucose metabolism, antioxidative capacity and heat shock protein (HSP) defence in different skeletal muscle phenotypes among middl...

journal_title：BMC endocrine disorders

authors： Venojärvi M,Aunola S,Puhke R,Marniemi J,Hämäläinen H,Halonen JP,Lindström J,Rastas M,Hällsten K,Nuutila P,Hänninen O,Atalay M

更新日期：2008-03-27 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the association between blood manganese levels and the prevalence of chronic diseases in the Korean population. METHODS:This was a cross-sectional study based on the Korean National Health and Nutrition Examination Survey (KNAHNES). The study included 3996 participa...

journal_title：BMC endocrine disorders

authors： Koh ES,Kim SJ,Yoon HE,Chung JH,Chung S,Park CW,Chang YS,Shin SJ

更新日期：2014-03-08 00:00:00

abstract：BACKGROUND:The burden of non-communicable diseases is growing rapidly in low- and middle-income countries. Research suggests that health interventions that aim to improve patient self-management and empower patients to care actively for their disease will improve health outcomes over the long-term. There is, however, a...

journal_title：BMC endocrine disorders

authors： Abrahams N,Gilson L,Levitt NS,Dave JA

更新日期：2019-12-05 00:00:00