Abstract：
BACKGROUND:Pituitary disorders following pregnancy are an important yet under reported clinical entity in the developing world. Conversely, post partum panhypopituitarism has a more devastating impact on women in such settings due to high fertility rates, poor obstetric care and scarcity of diagnostic and therapeutic resources available. CASE PRESENTATION:A 37 year old African female presented ten years post partum with features of multiple endocrine deficiencies including hypothyroidism, hypoadrenalism, lactation failure and secondary amenorrhea. In addition she had clinical features of an underlying autoimmune condition. These included a history of post-partum thyroiditis, alopecia areata, livedo reticularis and deranged coagulation indices. A remarkable clinical response followed appropriate hormone replacement therapy including steroids. This constellation has never been reported before; we therefore present an interesting clinical discussion including a brief review of existing literature. CONCLUSION:Post partum pituitary insufficiency is an under-reported condition of immense clinical importance especially in the developing world. A high clinical index of suspicion is vital to ensure an early and correct diagnosis which will have a direct bearing on management and patient outcome.
journal_name
BMC Endocr Disordjournal_title
BMC endocrine disordersauthors
Sheriff FG,Howlett WP,Kilonzo KGdoi
10.1186/1472-6823-12-4subject
Has Abstractpub_date
2012-07-10 00:00:00pages
4issn
1472-6823pii
1472-6823-12-4journal_volume
12pub_type
杂志文章abstract：BACKGROUND:Ovarian reserve, vital for reproductive function, can be adversely affected by thyroid diseases. Despite alternations of thyroid hormones with ageing, data on interactions between the overtime trend of thyroid functions and ovarian reserve status has rarely been reported. We aimed to examine the overtime tre...
journal_title：BMC endocrine disorders
pub_type： 杂志文章
doi：10.1186/s12902-019-0370-7
更新日期：2019-05-07 00:00:00
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journal_title：BMC endocrine disorders
pub_type： 杂志文章,meta分析
doi：10.1186/s12902-019-0347-6
更新日期：2019-02-13 00:00:00
abstract：BACKGROUND:Most of the patients with type 1 and V hyperlipoproteinemia (HLP) present with symptoms and signs of acute pancreatitis due to marked elevation of triglycerides, but this baby presented with a chest infection, which was later diagnosed as type V HLP on laboratory workup. CASE PRESENTATION:We report a case o...
journal_title：BMC endocrine disorders
pub_type： 杂志文章
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更新日期：2020-02-11 00:00:00
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journal_title：BMC endocrine disorders
pub_type： 杂志文章
doi：10.1186/1472-6823-13-33
更新日期：2013-08-23 00:00:00
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journal_title：BMC endocrine disorders
pub_type： 杂志文章
doi：10.1186/s12902-020-00572-x
更新日期：2020-06-16 00:00:00
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pub_type： 杂志文章
doi：10.1186/1472-6823-9-8
更新日期：2009-02-25 00:00:00
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journal_title：BMC endocrine disorders
pub_type： 杂志文章
doi：10.1186/1472-6823-11-7
更新日期：2011-03-22 00:00:00
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journal_title：BMC endocrine disorders
pub_type： 杂志文章
doi：10.1186/s12902-016-0111-0
更新日期：2016-07-07 00:00:00
abstract：:BACKGROUND: The possible participation of endogenous islet catecholamines (CAs) in the control of insulin secretion was tested. METHODS: Glucose-induced insulin secretion was measured in the presence of 3-Iodo-L-Tyrosine (MIT), a specific inhibitor of tyrosine-hydroxylase activity, in fresh and precultured islets isol...
journal_title：BMC endocrine disorders
pub_type： 杂志文章
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更新日期：2001-01-01 00:00:00
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journal_title：BMC endocrine disorders
pub_type： 杂志文章
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更新日期：2015-10-29 00:00:00
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journal_title：BMC endocrine disorders
pub_type： 杂志文章
doi：10.1186/1472-6823-13-9
更新日期：2013-03-01 00:00:00
abstract：BACKGROUND:Primary care physicians (PCPs) are the main providers of diabetes care especially in resource-limited countries which experience extreme shortage of specialists. The present study aimed to evaluate PCPs' approach towards diabetes mellitus (DM) diagnosis, evaluation and management in Cameroon. METHODS:We car...
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pub_type： 杂志文章
doi：10.1186/s12902-015-0016-3
更新日期：2015-04-04 00:00:00
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journal_title：BMC endocrine disorders
pub_type： 杂志文章,多中心研究,随机对照试验
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更新日期：2014-12-12 00:00:00
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journal_title：BMC endocrine disorders
pub_type： 杂志文章
doi：10.1186/1472-6823-14-1
更新日期：2014-01-02 00:00:00
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pub_type： 杂志文章
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更新日期：2015-12-03 00:00:00
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pub_type： 杂志文章
doi：10.1186/1472-6823-12-5
更新日期：2012-05-30 00:00:00
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pub_type： 杂志文章
doi：10.1186/s12902-020-00567-8
更新日期：2020-06-09 00:00:00
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pub_type： 杂志文章
doi：10.1186/s12902-016-0097-7
更新日期：2016-04-09 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章,评审
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pub_type： 杂志文章
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更新日期：2018-01-27 00:00:00
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pub_type： 杂志文章
doi：10.1186/1472-6823-14-92
更新日期：2014-12-01 00:00:00
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pub_type： 杂志文章
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更新日期：2014-07-03 00:00:00
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pub_type： 临床试验,杂志文章
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更新日期：2019-05-29 00:00:00
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pub_type： 杂志文章
doi：10.1186/s12902-020-0492-y
更新日期：2020-01-28 00:00:00
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pub_type： 杂志文章
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journal_title：BMC endocrine disorders
pub_type： 杂志文章
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更新日期：2012-06-27 00:00:00
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journal_title：BMC endocrine disorders
pub_type： 杂志文章
doi：10.1186/s12902-018-0238-2
更新日期：2018-02-13 00:00:00
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pub_type： 杂志文章
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更新日期：2020-09-29 00:00:00
