Metabolite biomarkers of type 2 diabetes mellitus and pre-diabetes: a systematic review and meta-analysis.

abstract：BACKGROUND:While poor sleep quality can worsen cardiovascular risk factors such as glucose and lipid profiles in patients with type 2 diabetes mellitus (T2DM), the relationship between sleep quality and atherosclerosis remains largely unknown. The aim of this study was to examine this relationship. METHODS:The study p...

journal_title：BMC endocrine disorders

authors： Osonoi Y,Mita T,Osonoi T,Saito M,Tamasawa A,Nakayama S,Someya Y,Ishida H,Kanazawa A,Gosho M,Fujitani Y,Watada H

更新日期：2015-06-18 00:00:00

abstract：BACKGROUND:Irisin is a myokine that leads to increased energy expenditure by stimulating the browning of white adipose tissue. We aimed to investigate the association of serum irisin levels with metabolic parameters in middle aged Chinese population. METHODS:The study was based on a cross-sectional analysis of data fr...

journal_title：BMC endocrine disorders

authors： Tang L,Tong Y,Zhang F,Chen G,Zhang YC,Jobin J,Tong N

更新日期：2019-12-27 00:00:00

abstract：BACKGROUND:Limited real-world data are currently available on hypoglycemia in diabetes patients. The International Operations Hypoglycemia Assessment Tool (IO HAT) study was designed to estimate hypoglycemia in insulin-treated type I (T1DM) and type II (T2DM) diabetes mellitus patients from 9 countries. The data from T...

journal_title：BMC endocrine disorders

authors： Emral R,Tetiker T,Sahin I,Sari R,Kaya A,Yetkin İ,Cil SU,Tütüncü NB,IO HAT investigator group.

更新日期：2018-02-13 00:00:00

abstract：BACKGROUND:Parathyroid carcinoma is a rare neoplasm that may present sporadically or in the context of a genetic syndrome. Diagnosis and management are challenging due to the lack of clinical and pathological features that may reliably distinguish malignant from benign disease. METHODS:From January 2013 to December 20...

journal_title：BMC endocrine disorders

authors： Ferraro V,Sgaramella LI,Di Meo G,Prete FP,Logoluso F,Minerva F,Noviello M,Renzulli G,Gurrado A,Testini M

更新日期：2019-05-29 00:00:00

abstract：BACKGROUND:To evaluate the impact of treatment with recombinant human growth hormone (rhGH; Omnitrope®) on the risk of diabetes mellitus in adults with growth hormone deficiency (GHD), using data from the ongoing PATRO Adults post-marketing surveillance study. METHODS:PATRO Adults is an ongoing post-marketing surveill...

journal_title：BMC endocrine disorders

authors： Beck-Peccoz P,Höybye C,Murray RD,Simsek S,Zabransky M,Zouater H,Stalla G

更新日期：2019-12-11 00:00:00

abstract：BACKGROUND:Several studies have shown that normal weight with central obesity (NWCO) is associated with cardiovascular disease risk factors such as hypertension, dyslipidemia and diabetes. However, the relationship between NWCO and hyperuricemia has not been studied in detail. METHODS:We investigated the association b...

journal_title：BMC endocrine disorders

authors： Shirasawa T,Ochiai H,Yoshimoto T,Nagahama S,Watanabe A,Yoshida R,Kokaze A

更新日期：2020-01-06 00:00:00

abstract：BACKGROUND:To estimate the proportion of diabetic patients (DPts) with peripheral vascular disease treated at a primary health care site after an endocrinologist-based intervention, who meet ATP III and Steno targets of metabolic control, as well as to compare the outcome with the results of the patients treated by end...

journal_title：BMC endocrine disorders

authors： Duran A,Runkle I,Matía P,de Miguel MP,Garrido S,Cervera E,Fernandez MD,Torres P,Lillo T,Martin P,Cabrerizo L,de la Torre NG,Calle JR,Ibarra J,Charro AL,Calle-Pascual AL

更新日期：2008-07-31 00:00:00

abstract：BACKGROUND:The discovery of sodium-glucose co-transporter 2 (SGLT2) inhibitors, with a novel mechanism independent of insulin secretion or sensitization, bring about a new therapeutic approach to the management of type 2 diabetes mellitus. The aim of this meta-analysis was to evaluate the safety and efficacy of SGLT2 i...

journal_title：BMC endocrine disorders

authors： Berhan A,Barker A

更新日期：2013-12-17 00:00:00

abstract：BACKGROUND:We quantified, among diabetic adults, the frequency, costs, and factors associated with visits to the emergency department (EDs) and subsequent hospitalizations for acute hypoglycaemic and hyperglycaemic events. METHODS:We included adults with diabetes residing in the Milan Agency for Health Protection betw...

journal_title：BMC endocrine disorders

authors： Andreano A,Bosio M,Russo AG

更新日期：2020-05-19 00:00:00

abstract：BACKGROUND:The nonthyroidal illness syndrome (NTIS) is prevalent among patients with enterocutaneous fistula and is associated with poor outcomes. The present study aimed to explore the role of enteral nutrition (EN) therapy on thyroid function among patients with enterocutaneous fistula and NTIS. METHODS:We conducted...

journal_title：BMC endocrine disorders

authors： Li R,Ren J,Wu Q,Wang G,Wu X,Chen J,Li G,Hong Z,Ren H,Zhao Y,Li J

更新日期：2015-11-04 00:00:00

abstract：BACKGROUND:Sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) proteins have an important role in counteracting oxidative stress. Although diabetes and hypothyroidism (HT) are both characterized by oxidative stress, the mechanisms are not fully understood. This study investigated the effects of type 1 diabetes (T1D), type 2 diabet...

journal_title：BMC endocrine disorders

authors： Al-Khaldi A,Sultan S

更新日期：2019-02-08 00:00:00

abstract：:ABSTRACT : BACKGROUND : The combination of transfusion and chelation therapy has dramatically extended the life expectancy of thalassemic patients. The main objective of this study is to determine the prevalence of prominent thalassemia complications. METHODS : Two hundred twenty patients entered the study. Physicians...

journal_title：BMC endocrine disorders

authors： Shamshirsaz AA,Bekheirnia MR,Kamgar M,Pourzahedgilani N,Bouzari N,Habibzadeh M,Hashemi R,Shamshirsaz AA,Aghakhani S,Homayoun H,Larijani B

更新日期：2003-08-12 00:00:00

abstract：BACKGROUND:The burden of non-communicable diseases is growing rapidly in low- and middle-income countries. Research suggests that health interventions that aim to improve patient self-management and empower patients to care actively for their disease will improve health outcomes over the long-term. There is, however, a...

journal_title：BMC endocrine disorders

authors： Abrahams N,Gilson L,Levitt NS,Dave JA

更新日期：2019-12-05 00:00:00

abstract：BACKGROUND:As an insulin-dependent disease, type 1 diabetes requires paying close attention to the glycemic control. Studies have shown that mobile health (mHealth) can improve the management of chronic diseases. However, the effectiveness of mHealth in controlling the glycemic control remains uncertain. The objective ...

journal_title：BMC endocrine disorders

authors： Wang X,Shu W,Du J,Du M,Wang P,Xue M,Zheng H,Jiang Y,Yin S,Liang D,Wang R,Hou L

更新日期：2019-02-13 00:00:00

abstract：BACKGROUND:Acromegaly is highly associated with thyroid disorders. However, the clinical characteristics of thyroid nodules in individuals with acromegaly who present with thyroid diseases have not been completely elucidated. METHODS:Overall, 134 consecutive participants with growth hormone (GH)-secreting adenoma (n =...

journal_title：BMC endocrine disorders

authors： Xu D,Wu B,Li X,Cheng Y,Chen D,Fang Y,Du Q,Chen Z,Wang X

更新日期：2019-09-02 00:00:00

abstract：BACKGROUND:Vitamin D deficiency is pandemic while resources available to measure 25-hydroxyvitamin D (25OHD) are limited. The present study aimed to verify whether sun exposure measured by a structured questionnaire could predict serum 25OHD concentrations in healthy Caucasian individuals living in a tropical area. ME...

journal_title：BMC endocrine disorders

authors： Bittar FB,Castro CHM,Szejnfeld VL

更新日期：2018-07-03 00:00:00

abstract：BACKGROUND:Whether lower dose cabergoline therapy for hyperprolactinemia increases risk of valvular dysfunction remains controversial. We examined valvular abnormalities among asymptomatic adults with hyperprolactinemia treated with dopamine agonists. METHODS:This cross-sectional study was conducted among adults recei...

journal_title：BMC endocrine disorders

authors： Budayr A,Tan TC,Lo JC,Zaroff JG,Tabada GH,Yang J,Go AS

更新日期：2020-02-19 00:00:00

abstract：BACKGROUND:A growing body of evidence supports neutrophils as having an active role in the development of diabetic kidney disease (DKD). However, the clinical relevance of neutrophils and DKD in autoimmune diabetes remains unknown. This study aimed to investigate the relationship between circulating neutrophils and DKD...

journal_title：BMC endocrine disorders

authors： Yu Y,Lin Q,Ye D,Wang Y,He B,Li Y,Huang G,Zhou Z,Xiao Y

更新日期：2020-10-22 00:00:00

abstract：BACKGROUND:The major cause of primary hypothyroidism is autoimmune mediated with progressive and permanent destruction of the thyroid gland resulting in life-long replacement therapy. Treatable and reversible hypothyroidism is unusual and here forth is such a case due to infection of the thyroid gland with Tropheryma w...

journal_title：BMC endocrine disorders

authors： Tran HA

更新日期：2006-05-10 00:00:00

abstract：BACKGROUND:Rosiglitazone not only improves insulin-sensitivity, but also exerts anti-inflammatory effects. We have now examined in type 2 diabetic patients if these effects are reflected by changes in mRNA expression in peripheral blood mononuclear cells (PBMCs) to see if these cells can be used to study these anti-inf...

journal_title：BMC endocrine disorders

authors： Bragt MC,Plat J,Mensink M,Schrauwen P,Mensink RP

更新日期：2009-02-25 00:00:00

abstract：BACKGROUND:The aim of the present study of the general population was to identify the best predictor of metabolic risk among the body index variables evaluated with dual-energy X-ray absorptiometry (DEXA) or anthropometric indices including the waist to height ratio (WHtR). PATIENTS AND METHODS:Data from the Korean Na...

journal_title：BMC endocrine disorders

authors： Kang SH,Cho KH,Park JW,Do JY

更新日期：2015-12-08 00:00:00

abstract：BACKGROUND:Radioisotope scanning is important to diagnose subacute thyroiditis (SAT), but it's not always available. So we aim to establish a diagnostic scale for SAT without radioisotope scanning. METHODS:The suspected SAT patients hospitalized in Yuebei people's Hospital from January 2012 to December 2016 were selec...

journal_title：BMC endocrine disorders

authors： Xiong Z,Luo C,Wang L,Xiong B,Wu J

更新日期：2020-05-27 00:00:00

abstract：BACKGROUND:Pituitary metastasis is a rare condition with a poor prognosis. Very few patients with pituitary metastasis are symptomatic. It is often associated with presence of co-existing metastases to other organs. Isolated pituitary metastasis as the first presentation of primary malignancy is uncommon. CASE PRESENT...

journal_title：BMC endocrine disorders

authors： Sirinvaravong S,Vibhatavata P,Chunharojrith P,Cheunsuchon P,Sriussadaporn S

更新日期：2019-10-29 00:00:00

abstract：:Oxytocin (OT) emerges as a drug for the treatment of diabetes and obesity. The entire OT system is synthesized in the rat and human heart. The direct myocardial infusion with OT into an ischemic or failing heart has the potential to elicit a variety of cardioprotective effects. OT treatment attenuates cardiomyocyte (C...

journal_title：BMC endocrine disorders

authors： Jankowski M,Broderick TL,Gutkowska J

更新日期：2016-06-07 00:00:00

abstract：BACKGROUND:Type 2 diabetes is a common and costly illness, associated with significant morbidity and mortality. Despite this, there is relatively little information on the 'real-world' medication utilization patterns for patients with type 2 diabetes initiating exenatide BID or glargine. The objective of this study was...

journal_title：BMC endocrine disorders

authors： Pawaskar M,Bonafede M,Johnson B,Fowler R,Lenhart G,Hoogwerf B

更新日期：2013-06-22 00:00:00

abstract：BACKGROUND:Chronic insulin resistance, exacerbated in the course of pregnancy, is an important pathophysiologic mechanism of gestational diabetes mellitus (GDM). We hypothesise that the degree of insulin resistance, assessed at diagnosis of GDM, is a parameter of its pathophysiologic heterogeneity and/or severity. Thus...

journal_title：BMC endocrine disorders

authors： Sokup A,Ruszkowska-Ciastek B,Góralczyk K,Walentowicz M,Szymański M,Rość D

更新日期：2013-07-02 00:00:00

abstract：UNLABELLED: BACKGROUND:Hypoglycaemia is a serious adverse effect of antidiabetic drug therapy. We aimed to determine incidence rates of hypoglycaemia in type-2 diabetic patients and identify predictors of hypoglycaemia when treatment is intensified. METHODS:DiaRegis is a prospective German registry that follows 3810 ...

journal_title：BMC endocrine disorders

authors： Tschöpe D,Bramlage P,Binz C,Krekler M,Deeg E,Gitt AK

更新日期：2012-10-17 00:00:00

abstract：BACKGROUND:Islet cell transplantation is a method to stabilize type 1 diabetes patients with hypoglycemia unawareness and unstable blood glucose levels by reducing insulin dependency and protecting against severe hypoglycemia through restoring endogenous insulin secretion. This study analyses the current cost-effective...

journal_title：BMC endocrine disorders

authors： Wallner K,Shapiro AM,Senior PA,McCabe C

更新日期：2016-04-09 00:00:00

abstract：BACKGROUND:Thyrotoxicosis is often caused by destructive thyroiditis (DT) or Graves' disease (GD), and a prompt and accurate differential diagnosis for thyrotoxicosis is needed as management strategy differs. A meta-analysis of published literature was performed to evaluate the diagnostic accuracy for differentiating G...

journal_title：BMC endocrine disorders

authors： Peng X,Wu S,Bie C,Tang H,Xiong Z,Tang S

更新日期：2019-06-06 00:00:00

abstract：BACKGROUND:Diabetes is a major public health problem worldwide. This problem is particularly relevant to the elderly. The prevalence of each condition increase with age. The present study aimed to determine the prevalence of Diabetes Mellitus (DM) among elderly; we also examined socio-economic factors and life style th...

journal_title：BMC endocrine disorders

authors： Hammami S,Mehri S,Hajem S,Koubaa N,Souid H,Hammami M

更新日期：2012-08-16 00:00:00