Abstract:
BACKGROUND:Diabetic foot is an underestimated and redoubtable diabetes complication. The aims of our study were to assess diabetic foot ulcer risk factors according to International Working Group on the Diabetic Foot (IWGDF) classification, stratify patients into risk categories and identify factors associated with higher-risk grade. METHODS:Cross-sectional setting over a period of 07 months, patients were randomly selected from the diabetic outpatients attending our unit of diabetology. Questionnaire and clinical examination were made by the same physician. Patients free of active foot ulcer were included. RESULTS:Among 230 patients evaluated, 10 had an active foot ulcer and were excluded. Five patients (2.27%) had a history of foot ulcer and 3(1.36%) had a lower-limb amputation. Sensory neuropathy, as measured by the 5.07(10 g) Semmes-Weinstein monofilament testing, was present in 23.63% of patients, whereas 36.82% had a peripheral arterial disease based on clinical findings, and 43.63% had foot deformities. According to the IWGDF classification, Group 0: 72.72%, Group 1: 5.9%, Group 2: 17.73% and Group 3: 3.63%. After univariate analysis, patients in higher-risk groups were significantly more often female, had higher age and BMI, longer diabetes duration, elevated waist circumference, low school level, retinopathy and hyperkeratosis. Multivariate logistic regression analysis identified 3 significant independent factors associated with high-risk groups: retinopathy (OR = 2.529, CI95 [1.131-5.655], p = 0.024), hyperkeratosis (OR = 2.658, CI95 [1.222-5.783], p = 0.014) and school level (OR = 0.489, CI95 [0.253-9.44], p = 0.033). CONCLUSIONS:Risk factors for foot ulceration were rather common in outpatients with diabetes. The screening of patients at risk for foot ulceration should start early, integrated with sustainable patient education.
journal_name
BMC Endocr Disordjournal_title
BMC endocrine disordersauthors
Zantour B,Bouchareb S,El Ati Z,Boubaker F,Alaya W,Kossomtini W,Sfar MHdoi
10.1186/s12902-020-00608-2subject
Has Abstractpub_date
2020-08-24 00:00:00pages
128issue
1issn
1472-6823pii
10.1186/s12902-020-00608-2journal_volume
20pub_type
杂志文章abstract:BACKGROUND:We aimed to explore metabolite biomarkers that could be used to identify pre-diabetes and type 2 diabetes mellitus (T2DM) using systematic review and meta-analysis. METHODS:Four databases, the Cochrane Library, EMBASE, PubMed and Scopus were selected. A random effect model and a fixed effect model were appl...
journal_title:BMC endocrine disorders
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更新日期:2020-11-23 00:00:00
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pub_type: 杂志文章
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-12-11
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abstract:BACKGROUND:Ectopic adrenocorticotropic hormone (ACTH) syndrome (EAS) is caused by tumours releasing ACTH. Ectopic ACTH-producing tumour regression is rarely induced using steroidogenesis inhibitors. We presented a case of EAS in which ACTH production by a lung tumour was reduced by metyrapone (MTP) and also reviewed pr...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
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abstract:BACKGROUND:Limited real-world data are currently available on hypoglycemia in diabetes patients. The International Operations Hypoglycemia Assessment Tool (IO HAT) study was designed to estimate hypoglycemia in insulin-treated type I (T1DM) and type II (T2DM) diabetes mellitus patients from 9 countries. The data from T...
journal_title:BMC endocrine disorders
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doi:10.1186/s12902-018-0238-2
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pub_type: 杂志文章,meta分析
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pub_type: 杂志文章,评审
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journal_title:BMC endocrine disorders
pub_type: 杂志文章,meta分析,评审
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pub_type: 杂志文章,多中心研究
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abstract::BACKGROUND: The possible participation of endogenous islet catecholamines (CAs) in the control of insulin secretion was tested. METHODS: Glucose-induced insulin secretion was measured in the presence of 3-Iodo-L-Tyrosine (MIT), a specific inhibitor of tyrosine-hydroxylase activity, in fresh and precultured islets isol...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-1-1
更新日期:2001-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1186/1472-6823-14-1
更新日期:2014-01-02 00:00:00
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pub_type: 杂志文章,随机对照试验
doi:10.1186/s12902-019-0466-0
更新日期:2019-12-11 00:00:00
abstract:BACKGROUND:Diabetes mellitus (DM) is a global health care problem that can impose a substantial economic burden. Diabetic peripheral neuropathy (DPN) is a common microvascular complication of DM that increases the potential for morbidity and disability due to ulceration and amputation. Though there is a significant amo...
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pub_type: 杂志文章
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-9-8
更新日期:2009-02-25 00:00:00
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pub_type: 杂志文章
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更新日期:2009-05-16 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
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更新日期:2008-10-13 00:00:00
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pub_type: 杂志文章
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更新日期:2015-10-24 00:00:00
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pub_type: 杂志文章
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更新日期:2014-07-03 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-12-5
更新日期:2012-05-30 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-020-00569-6
更新日期:2020-07-08 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-13-50
更新日期:2013-11-02 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-12-1
更新日期:2012-03-07 00:00:00
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pub_type: 杂志文章
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更新日期:2014-03-08 00:00:00