Oxytocin and cardioprotection in diabetes and obesity.

abstract：UNLABELLED: BACKGROUND:The use of chromium supplements is widespread for the prevention and treatment of diabetes mellitus but there are conflicting reports on efficacy, possibly reflecting discrepant effects across different populations. In the present studies, we test the hypothesis that chromium supplementation rai...

journal_title：BMC endocrine disorders

authors： Masharani U,Gjerde C,McCoy S,Maddux BA,Hessler D,Goldfine ID,Youngren JF

更新日期：2012-11-30 00:00:00

abstract：UNLABELLED: BACKGROUND:Severe hypoglycaemia (SH) is one of the most feared complications of type 1 diabetes (T1DM) with a reported prevalence of nearly 40%. In randomized trials of Multiple Daily Injections (MDI) and Continuous Subcutaneous Insulin Infusion (CSII) therapy there is a possible benefit of CSII in reducin...

journal_title：BMC endocrine disorders

authors： Little S,Chadwick T,Choudhary P,Brennand C,Stickland J,Barendse S,Olateju T,Leelarathna L,Walkinshaw E,Tan HK,Marshall SM,Thomas RM,Heller S,Evans M,Kerr D,Flanagan D,Speight J,Shaw JA

更新日期：2012-12-13 00:00:00

abstract：BACKGROUND:Thyrotoxicosis is often caused by destructive thyroiditis (DT) or Graves' disease (GD), and a prompt and accurate differential diagnosis for thyrotoxicosis is needed as management strategy differs. A meta-analysis of published literature was performed to evaluate the diagnostic accuracy for differentiating G...

journal_title：BMC endocrine disorders

authors： Peng X,Wu S,Bie C,Tang H,Xiong Z,Tang S

更新日期：2019-06-06 00:00:00

abstract：BACKGROUND:Alogliptin is a new dipeptidyl peptidase (DPP-4) inhibitor, which is under investigation for treatment of type 2 diabetes either alone or in combination with other antidiabetic drugs. The aim of this meta-analysis was to assess the efficacy and tolerability of alogliptin in patients with type 2 diabetes. ME...

journal_title：BMC endocrine disorders

authors： Berhan A,Berhan Y

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Hypoglycemia is a common complication of diabetes treatment. This paper describes symptoms, predecessors, consequences and medications associated with the first episode of severe hypoglycemia among ACCORD participants with type 2 diabetes, and compares these between intensive (Int: goal A1C <6.0%) and standa...

journal_title：BMC endocrine disorders

authors： Bonds DE,Miller ME,Dudl J,Feinglos M,Ismail-Beigi F,Malozowski S,Seaquist E,Simmons DL,Sood A

更新日期：2012-05-30 00:00:00

abstract：BACKGROUND:Hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome is a rare autosomal dominant disorder caused by mutations in the zinc finger transcription factor gene, GATA3. GATA3 has 2 zinc finger domains, which play an important role in the increase in target gene transcription activity. CASE PRESENTATI...

journal_title：BMC endocrine disorders

authors： Okawa T,Yoshida M,Usui T,Kudou T,Iwasaki Y,Fukuoka K,Takahashi N,Uehara Y,Oiso Y

更新日期：2015-10-30 00:00:00

abstract：BACKGROUND:To evaluate the impact of treatment with recombinant human growth hormone (rhGH; Omnitrope®) on the risk of diabetes mellitus in adults with growth hormone deficiency (GHD), using data from the ongoing PATRO Adults post-marketing surveillance study. METHODS:PATRO Adults is an ongoing post-marketing surveill...

journal_title：BMC endocrine disorders

authors： Beck-Peccoz P,Höybye C,Murray RD,Simsek S,Zabransky M,Zouater H,Stalla G

更新日期：2019-12-11 00:00:00

abstract：BACKGROUND:Type 2 diabetic patients display significantly higher incidence of cardiovascular (CV) events including stroke compared to non-diabetics. Morning blood pressure surge (MBPS) and blunted systolic night-day (SND) ratio have been associated with CV events in hypertensive patients. No studies have evaluated MBPS...

journal_title：BMC endocrine disorders

authors： Lyhne JM,Laugesen E,Høyem P,Cichosz S,Christiansen JS,Knudsen ST,Hansen KW,Hansen TK,Poulsen PL

更新日期：2015-12-03 00:00:00

abstract：BACKGROUND:Our aim was to assess the associations between vitamin D (vitD) status, metabolic profile and polymorphisms in genes involved in the transport (Group-Component: GC) and the hydroxylation (NAD synthetase 1: NADSYN1) of 25 hydroxyvitamin D (25(OH)D) in non-diabetic individuals. METHODS:We conducted a cross-se...

journal_title：BMC endocrine disorders

authors： Foucan L,Vélayoudom-Céphise FL,Larifla L,Armand C,Deloumeaux J,Fagour C,Plumasseau J,Portlis ML,Liu L,Bonnet F,Ducros J

更新日期：2013-09-29 00:00:00

abstract：BACKGROUND:As a member of peroxiredoxin (PRX) family, PRX3 is predominantly located in mitochondria and plays an important role of free radical scavenging. Since a body of evidence demonstrated the involvement of PRX3 in insulin secretion, insulin sensitivity, and glucose metabolism, the present study was conducted to ...

journal_title：BMC endocrine disorders

authors： Liu HL,Li TT,Yu AQ,Li J,Li X,Li L,Kaifu T

更新日期：2019-03-14 00:00:00

abstract：BACKGROUND:The burden of non-communicable diseases is growing rapidly in low- and middle-income countries. Research suggests that health interventions that aim to improve patient self-management and empower patients to care actively for their disease will improve health outcomes over the long-term. There is, however, a...

journal_title：BMC endocrine disorders

authors： Abrahams N,Gilson L,Levitt NS,Dave JA

更新日期：2019-12-05 00:00:00

abstract：BACKGROUND:The objective was to examine how the indigenous naming, indigenous self-diagnosis and management of diabetes evolved with awareness in order to develop a socially oriented theoretical model for its care. METHODS:The data was collected through a one-year extended participant observation in Bafut, a rural hea...

journal_title：BMC endocrine disorders

authors： Awah PK,Unwin NC,Phillimore PR

更新日期：2009-02-19 00:00:00

abstract：BACKGROUND:We aimed to explore metabolite biomarkers that could be used to identify pre-diabetes and type 2 diabetes mellitus (T2DM) using systematic review and meta-analysis. METHODS:Four databases, the Cochrane Library, EMBASE, PubMed and Scopus were selected. A random effect model and a fixed effect model were appl...

journal_title：BMC endocrine disorders

authors： Long J,Yang Z,Wang L,Han Y,Peng C,Yan C,Yan D

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:Non-thyroidal illness (NTI) refers to changes in thyroid hormone levels in critically ill patients in the absence of primary hypothalamic-pituitary-thyroid dysfunction, and these abnormalities usually resolve after clinical recovery. However, NTI can be accompanied by primary thyroid dysfunction. We report h...

journal_title：BMC endocrine disorders

authors： Cho EA,Yoon JH,Kim HK,Kang HC

更新日期：2014-01-02 00:00:00

abstract：BACKGROUND:Type 2 diabetes is a common and costly illness, associated with significant morbidity and mortality. Despite this, there is relatively little information on the 'real-world' medication utilization patterns for patients with type 2 diabetes initiating exenatide BID or glargine. The objective of this study was...

journal_title：BMC endocrine disorders

authors： Pawaskar M,Bonafede M,Johnson B,Fowler R,Lenhart G,Hoogwerf B

更新日期：2013-06-22 00:00:00

abstract：BACKGROUND:Previous studies have shown inconsistent results about the usefulness of bilateral inferior petrosal sinus sampling (BIPSS) in differential diagnosis of adrenocorticotropic hormone (ACTH)-dependent Cushing syndrome. This meta-analysis evaluated the diagnostic value of BIPSS via the published literature. MET...

journal_title：BMC endocrine disorders

authors： Wang H,Ba Y,Xing Q,Cai RC

更新日期：2020-09-17 00:00:00

abstract：BACKGROUND:Insufficient vitamin D status and increased renin-angiotensin system (RAS) activity have been associated with renal-vascular disease and nephropathy in diabetes. Accumulating evidence indicates that vitamin D receptor (VDR) activation lowers unfavorable RAS activity; however, more human intervention studies ...

journal_title：BMC endocrine disorders

authors： Brown JM,Secinaro K,Williams JS,Vaidya A

更新日期：2013-08-23 00:00:00

abstract：BACKGROUND:Several studies have shown that normal weight with central obesity (NWCO) is associated with cardiovascular disease risk factors such as hypertension, dyslipidemia and diabetes. However, the relationship between NWCO and hyperuricemia has not been studied in detail. METHODS:We investigated the association b...

journal_title：BMC endocrine disorders

authors： Shirasawa T,Ochiai H,Yoshimoto T,Nagahama S,Watanabe A,Yoshida R,Kokaze A

更新日期：2020-01-06 00:00:00

abstract：BACKGROUND:Promyelocytic leukaemia zinc finger (PLZF) is a transcriptional repressor that was originally isolated from a patient with promyelocytic leukaemia. PLZF also affects key elements for cell cycle progression, such as cyclin A, and can affect the tumourigenicity of various cancers. Thus far, the behaviour of PL...

journal_title：BMC endocrine disorders

authors： Matsuzawa K,Izawa S,Ohkura T,Ohkura H,Ishiguro K,Yoshida A,Takiyama Y,Haneda M,Shigemasa C,Yamamoto K,Taniguchi S

更新日期：2014-07-03 00:00:00

abstract：BACKGROUND:Children whose mothers had low thyroid hormone levels during pregnancy have been reported to have decreased cognitive function. The reported research is part of the follow-on study of the Controlled Antenatal Thyroid Screening Study (CATS I), a randomised controlled trial which investigated the impact of tre...

journal_title：BMC endocrine disorders

authors： Hales C,Channon S,Taylor PN,Draman MS,Muller I,Lazarus J,Paradice R,Rees A,Shillabeer D,Gregory JW,Dayan CM,Ludgate M

更新日期：2014-12-12 00:00:00

abstract：BACKGROUND:Insulin resistance and diabetes are associated with increased oxidative stress and impairment of cellular defence systems. Our purpose was to investigate the interaction between glucose metabolism, antioxidative capacity and heat shock protein (HSP) defence in different skeletal muscle phenotypes among middl...

journal_title：BMC endocrine disorders

authors： Venojärvi M,Aunola S,Puhke R,Marniemi J,Hämäläinen H,Halonen JP,Lindström J,Rastas M,Hällsten K,Nuutila P,Hänninen O,Atalay M

更新日期：2008-03-27 00:00:00

abstract：BACKGROUND:Most studies on cortisol have focused on smaller, selected samples. We therefore aimed to sex-specifically study the diurnal cortisol pattern and explore its association with abdominal obesity in a large unselected population. METHODS:In 2001-2004, 1811 men and women (30-75 years) were randomly selected fro...

journal_title：BMC endocrine disorders

authors： Larsson CA,Gullberg B,Råstam L,Lindblad U

更新日期：2009-06-21 00:00:00

abstract：BACKGROUND:Vitamin D deficiency is pandemic while resources available to measure 25-hydroxyvitamin D (25OHD) are limited. The present study aimed to verify whether sun exposure measured by a structured questionnaire could predict serum 25OHD concentrations in healthy Caucasian individuals living in a tropical area. ME...

journal_title：BMC endocrine disorders

authors： Bittar FB,Castro CHM,Szejnfeld VL

更新日期：2018-07-03 00:00:00

abstract：: Pituitary adenomas are associated with a variety of clinical manifestations resulting from excessive hormone secretion and tumor mass effects, and require a multidisciplinary management approach. This article discusses the treatment modalities for the management of patients with a prolactinoma, Cushing's disease and ...

journal_title：BMC endocrine disorders

authors： Biller BM,Colao A,Petersenn S,Bonert VS,Boscaro M

更新日期：2010-05-17 00:00:00

abstract：BACKGROUND:Anti-Müllerian hormone (AMH) is now considered the best serum biomarker of ovarian reserve, while basal sex hormones are classic markers used for assessing ovarian reserve. The interaction between AMH and sex hormones are complicated and not sufficiently addressed. In this study, we took diminished ovarian r...

journal_title：BMC endocrine disorders

authors： Lv PP,Jin M,Rao JP,Chen J,Wang LQ,Huang CC,Yang SQ,Yao QP,Feng L,Shen JM,Feng C

更新日期：2020-07-08 00:00:00

abstract：BACKGROUND:As an insulin-dependent disease, type 1 diabetes requires paying close attention to the glycemic control. Studies have shown that mobile health (mHealth) can improve the management of chronic diseases. However, the effectiveness of mHealth in controlling the glycemic control remains uncertain. The objective ...

journal_title：BMC endocrine disorders

authors： Wang X,Shu W,Du J,Du M,Wang P,Xue M,Zheng H,Jiang Y,Yin S,Liang D,Wang R,Hou L

更新日期：2019-02-13 00:00:00

abstract：BACKGROUND:Caloric restriction is an effective way to treat Type 2 diabetes (T2D). However, chronic and severe restriction of food intake is difficult to sustain and is known to promote slower metabolism. Intermittent and frequent fasting can exert similar metabolic effects, but may be even more challenging for most pa...

journal_title：BMC endocrine disorders

authors： van den Burg EL,Schoonakker MP,van Peet PG,van den Akker-van Marle ME,Willems van Dijk K,Longo VD,Lamb HJ,Numans ME,Pijl H

更新日期：2020-06-24 00:00:00

abstract：BACKGROUND:Telomeres are DNA repeat sequences necessary for DNA replication which shorten at cell division at a rate directly related to levels of oxidative stress. Critical telomere shortening predisposes to cell senescence and to epithelial malignancies. Type 2 diabetes is characterised by increased oxidative DNA dam...

journal_title：BMC endocrine disorders

authors： Kejariwal D,Stepien KM,Smith T,Kennedy H,Hughes DA,Sampson MJ

更新日期：2008-10-10 00:00:00

abstract：BACKGROUND:The discovery of sodium-glucose co-transporter 2 (SGLT2) inhibitors, with a novel mechanism independent of insulin secretion or sensitization, bring about a new therapeutic approach to the management of type 2 diabetes mellitus. The aim of this meta-analysis was to evaluate the safety and efficacy of SGLT2 i...

journal_title：BMC endocrine disorders

authors： Berhan A,Barker A

更新日期：2013-12-17 00:00:00

abstract：BACKGROUND:Seminomas have been rarely associated with malignant hypercalcemia. The responsible mechanism of hypercalcemia in this setting has been described to be secondary to 1,25-dihydroxyvitamin D secretion. The relationship with PTHrP has not been determined or studied.The aim of this study is to describe and discu...

journal_title：BMC endocrine disorders

authors： Rodríguez-Gutiérrez R,Zapata-Rivera MA,Quintanilla-Flores DL,Camara-Lemarroy CR,Lavalle-Gonzalez FJ,González-González JG,Villarreal-Pérez JZ

更新日期：2014-04-10 00:00:00