Abstract:
BACKGROUND:Radioisotope scanning is important to diagnose subacute thyroiditis (SAT), but it's not always available. So we aim to establish a diagnostic scale for SAT without radioisotope scanning. METHODS:The suspected SAT patients hospitalized in Yuebei people's Hospital from January 2012 to December 2016 were selected and divided into study group and control group according to whether they were diagnosed as SAT. The clinical indexes of two groups were collected and the diagnostic scale of SAT was established by using binary logistic regression analysis. The effectiveness of the scale was evaluated by ROC curve. RESULTS:Of 309 patients, 58.25% of patients were confirmed with SAT and the remaining 41.75% of patients were not diagnosed with SAT. After univariate analysis, variables which were considered statistically different(P < 0. 05) between the two groups were selected as independent variables and the diagnosis of SAT was taken as dependent variable in the binary logistic regression model. The logistic regression model consisted of 4 variables, each was thyroid tenderness, firm on palpation, increased ESR and elevated thyroid hormone level. The P value of Omnibus tests was≤0. 001 and the Nagelkerke R Square was 0. 915. The diagnostic scoring scale was established with these four variables according to their regression coefficient. The area under the ROC curve for this diagnostic scale was 0. 991(95% confidence interval, 0. 982-0.999). The highest Youden index was 0. 912, the corresponding cut-off point was 7. Internally validation shows a sensitivity of 92. 78% and a specificity of 98.45% of our scale. CONCLUSIONS:We established and validated a diagnostic scale for SAT without the need for radioisotope scanning for the first time. It has good application in institutions that do not have radioisotope machines or among pregnant and lactating women.
journal_name
BMC Endocr Disordjournal_title
BMC endocrine disordersauthors
Xiong Z,Luo C,Wang L,Xiong B,Wu Jdoi
10.1186/s12902-020-00554-zsubject
Has Abstractpub_date
2020-05-27 00:00:00pages
74issue
1issn
1472-6823pii
10.1186/s12902-020-00554-zjournal_volume
20pub_type
杂志文章abstract:BACKGROUND:Rosiglitazone not only improves insulin-sensitivity, but also exerts anti-inflammatory effects. We have now examined in type 2 diabetic patients if these effects are reflected by changes in mRNA expression in peripheral blood mononuclear cells (PBMCs) to see if these cells can be used to study these anti-inf...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-9-8
更新日期:2009-02-25 00:00:00
abstract:BACKGROUND:Among patients with type 2 diabetes, insulin intensification to achieve glycemic targets occurs less often than clinically indicated. Barriers to intensification are not well understood. We present patients' baseline characteristics from MOSAIc, a study investigating patient-, physician-, and healthcare envi...
journal_title:BMC endocrine disorders
pub_type: 杂志文章,多中心研究
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更新日期:2015-09-09 00:00:00
abstract:BACKGROUND:Chronic kidney disease (CKD) is becoming a serious health problem; the number of people with impaired renal function is rapidly rising. Progression of CKD is associated with having a number of complications, including thyroid dysfunction, dyslipidemia and cardiovascular diseases. This study was conducted to ...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
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更新日期:2015-10-29 00:00:00
abstract:BACKGROUND:To evaluate the impact of treatment with recombinant human growth hormone (rhGH; Omnitrope®) on the risk of diabetes mellitus in adults with growth hormone deficiency (GHD), using data from the ongoing PATRO Adults post-marketing surveillance study. METHODS:PATRO Adults is an ongoing post-marketing surveill...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-019-0464-2
更新日期:2019-12-11 00:00:00
abstract:BACKGROUND:Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of childbearing age. This study aimed to compare the effects of lifestyle interventions on anthropometric, clinical, and biochemical parameters in adolescent girls with PCOS. METHODS:PubMed, Scopus, and Web of Science was system...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-020-00552-1
更新日期:2020-05-19 00:00:00
abstract:BACKGROUND:The major cause of primary hypothyroidism is autoimmune mediated with progressive and permanent destruction of the thyroid gland resulting in life-long replacement therapy. Treatable and reversible hypothyroidism is unusual and here forth is such a case due to infection of the thyroid gland with Tropheryma w...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-6-3
更新日期:2006-05-10 00:00:00
abstract::BACKGROUND: The possible participation of endogenous islet catecholamines (CAs) in the control of insulin secretion was tested. METHODS: Glucose-induced insulin secretion was measured in the presence of 3-Iodo-L-Tyrosine (MIT), a specific inhibitor of tyrosine-hydroxylase activity, in fresh and precultured islets isol...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
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更新日期:2001-01-01 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章,评审
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更新日期:2019-10-29 00:00:00
abstract:BACKGROUND:Diabetes self-management education can be helpful for patients with type 2 diabetes in managing their condition. We aimed to study the effects of the group-based PRoactive Interdisciplinary Self-MAnagement (PRISMA) training program on self-reported and clinical outcomes in patients with type 2 diabetes treat...
journal_title:BMC endocrine disorders
pub_type: 杂志文章,随机对照试验
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更新日期:2019-12-11 00:00:00
abstract:BACKGROUND:Hypoglycemia is a common complication of diabetes treatment. This paper describes symptoms, predecessors, consequences and medications associated with the first episode of severe hypoglycemia among ACCORD participants with type 2 diabetes, and compares these between intensive (Int: goal A1C <6.0%) and standa...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-12-5
更新日期:2012-05-30 00:00:00
abstract:BACKGROUND:Vitamin D deficiency is pandemic while resources available to measure 25-hydroxyvitamin D (25OHD) are limited. The present study aimed to verify whether sun exposure measured by a structured questionnaire could predict serum 25OHD concentrations in healthy Caucasian individuals living in a tropical area. ME...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-018-0272-0
更新日期:2018-07-03 00:00:00
abstract:UNLABELLED: BACKGROUND:Hypoglycaemia is a serious adverse effect of antidiabetic drug therapy. We aimed to determine incidence rates of hypoglycaemia in type-2 diabetic patients and identify predictors of hypoglycaemia when treatment is intensified. METHODS:DiaRegis is a prospective German registry that follows 3810 ...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-12-23
更新日期:2012-10-17 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-015-0065-7
更新日期:2015-10-30 00:00:00
abstract:BACKGROUND:Parathyroid carcinoma is a rare neoplasm that may present sporadically or in the context of a genetic syndrome. Diagnosis and management are challenging due to the lack of clinical and pathological features that may reliably distinguish malignant from benign disease. METHODS:From January 2013 to December 20...
journal_title:BMC endocrine disorders
pub_type: 临床试验,杂志文章
doi:10.1186/s12902-019-0368-1
更新日期:2019-05-29 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-13-33
更新日期:2013-08-23 00:00:00
abstract:BACKGROUND:Insulin and insulin-like growth factor (IGF)-1 coupled with growth hormone helps control timing of sexual maturation. Mutations and variants in multiple genes are associated with development or reduced risk of central precocious puberty (CPP). METHODS:We assessed single nucleotide polymorphisms (SNPs) in th...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-018-0271-1
更新日期:2018-09-19 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-017-0186-2
更新日期:2017-06-21 00:00:00
abstract:BACKGROUND:Islet cell transplantation is a method to stabilize type 1 diabetes patients with hypoglycemia unawareness and unstable blood glucose levels by reducing insulin dependency and protecting against severe hypoglycemia through restoring endogenous insulin secretion. This study analyses the current cost-effective...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-016-0097-7
更新日期:2016-04-09 00:00:00
abstract:BACKGROUND:Primary care physicians (PCPs) are the main providers of diabetes care especially in resource-limited countries which experience extreme shortage of specialists. The present study aimed to evaluate PCPs' approach towards diabetes mellitus (DM) diagnosis, evaluation and management in Cameroon. METHODS:We car...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-015-0016-3
更新日期:2015-04-04 00:00:00
abstract:BACKGROUND:The rising prevalence of type 2 diabetes underlines the importance of secondary strategies for the prevention of target organ damage. While access to diabetes education centers and diabetes intensification management has been shown to improve blood glucose control, these services are not available to all tha...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-9-13
更新日期:2009-05-09 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-12-1
更新日期:2012-03-07 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-015-0026-1
更新日期:2015-06-18 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-016-0107-9
更新日期:2016-05-23 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-018-0246-2
更新日期:2018-03-27 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-13-41
更新日期:2013-10-05 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章,多中心研究
doi:10.1186/1472-6823-14-46
更新日期:2014-06-10 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-020-00661-x
更新日期:2020-12-09 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
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更新日期:2020-09-17 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
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更新日期:2014-01-02 00:00:00
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journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-019-0482-0
更新日期:2019-12-28 00:00:00