Drug-related risk of severe hypoglycaemia in observational studies: a systematic review and meta-analysis.

abstract：: Pituitary adenomas are associated with a variety of clinical manifestations resulting from excessive hormone secretion and tumor mass effects, and require a multidisciplinary management approach. This article discusses the treatment modalities for the management of patients with a prolactinoma, Cushing's disease and ...

journal_title：BMC endocrine disorders

authors： Biller BM,Colao A,Petersenn S,Bonert VS,Boscaro M

更新日期：2010-05-17 00:00:00

abstract：UNLABELLED: BACKGROUND:Severe hypoglycaemia (SH) is one of the most feared complications of type 1 diabetes (T1DM) with a reported prevalence of nearly 40%. In randomized trials of Multiple Daily Injections (MDI) and Continuous Subcutaneous Insulin Infusion (CSII) therapy there is a possible benefit of CSII in reducin...

journal_title：BMC endocrine disorders

authors： Little S,Chadwick T,Choudhary P,Brennand C,Stickland J,Barendse S,Olateju T,Leelarathna L,Walkinshaw E,Tan HK,Marshall SM,Thomas RM,Heller S,Evans M,Kerr D,Flanagan D,Speight J,Shaw JA

更新日期：2012-12-13 00:00:00

abstract：BACKGROUND:In primary health care systems where member's turnover is relatively low, the question, whether investment in quality of care improvement can make a business case, or is cost effective, has not been fully answered.The objectives of this study were: (1) to investigate the relationship between improvement in s...

journal_title：BMC endocrine disorders

authors： Wilf-Miron R,Bolotin A,Gordon N,Porath A,Peled R

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Most studies on cortisol have focused on smaller, selected samples. We therefore aimed to sex-specifically study the diurnal cortisol pattern and explore its association with abdominal obesity in a large unselected population. METHODS:In 2001-2004, 1811 men and women (30-75 years) were randomly selected fro...

journal_title：BMC endocrine disorders

authors： Larsson CA,Gullberg B,Råstam L,Lindblad U

更新日期：2009-06-21 00:00:00

abstract：BACKGROUND:Insulin autoimmune syndrome (IAS) is a rare cause of hypoglycemia and is characterized by the presence of insulin autoantibodies. Patients with IAS usually complain of hypoglycemia without any previous insulin received. Glucocorticoids and immunosuppressants are used to treat IAS. CASE PRESENTATION:We repor...

journal_title：BMC endocrine disorders

authors： Shen Y,Song X,Ren Y

更新日期：2019-12-28 00:00:00

abstract：BACKGROUND:Previous studies have shown inconsistent results about the usefulness of bilateral inferior petrosal sinus sampling (BIPSS) in differential diagnosis of adrenocorticotropic hormone (ACTH)-dependent Cushing syndrome. This meta-analysis evaluated the diagnostic value of BIPSS via the published literature. MET...

journal_title：BMC endocrine disorders

authors： Wang H,Ba Y,Xing Q,Cai RC

更新日期：2020-09-17 00:00:00

abstract：BACKGROUND:Chronic insulin resistance, exacerbated in the course of pregnancy, is an important pathophysiologic mechanism of gestational diabetes mellitus (GDM). We hypothesise that the degree of insulin resistance, assessed at diagnosis of GDM, is a parameter of its pathophysiologic heterogeneity and/or severity. Thus...

journal_title：BMC endocrine disorders

authors： Sokup A,Ruszkowska-Ciastek B,Góralczyk K,Walentowicz M,Szymański M,Rość D

更新日期：2013-07-02 00:00:00

abstract：BACKGROUND:Sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) proteins have an important role in counteracting oxidative stress. Although diabetes and hypothyroidism (HT) are both characterized by oxidative stress, the mechanisms are not fully understood. This study investigated the effects of type 1 diabetes (T1D), type 2 diabet...

journal_title：BMC endocrine disorders

authors： Al-Khaldi A,Sultan S

更新日期：2019-02-08 00:00:00

abstract：BACKGROUND:Hyperglycemia induces chromatin remodeling with consequences on differential gene expression in mouse hepatocytes, similar to what occurs during aging. The liver is the central organ for the regulation of glucose homeostasis and xenobiotic and lipid metabolism and is affected by insulin signaling. The precis...

journal_title：BMC endocrine disorders

authors： Ghiraldini FG,Silveira AB,Kleinjan DA,Gilbert N,Mello ML

更新日期：2014-03-03 00:00:00

abstract：BACKGROUND:Lifestyle modification targeting weight management is the first-line treatment for women with Polycystic Ovary Syndrome (PCOS) regardless of presenting symptoms. Women with PCOS are more likely to gain more weight compared with women without PCOS, which may be related to barriers in engaging in lifestyle mod...

journal_title：BMC endocrine disorders

authors： Lim S,Smith CA,Costello MF,MacMillan F,Moran L,Ee C

更新日期：2019-10-23 00:00:00

abstract：BACKGROUND:Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of childbearing age. This study aimed to compare the effects of lifestyle interventions on anthropometric, clinical, and biochemical parameters in adolescent girls with PCOS. METHODS:PubMed, Scopus, and Web of Science was system...

journal_title：BMC endocrine disorders

authors： Abdolahian S,Tehrani FR,Amiri M,Ghodsi D,Yarandi RB,Jafari M,Majd HA,Nahidi F

更新日期：2020-05-19 00:00:00

abstract：BACKGROUND:Down syndrome (DS) has been described as one of the main contributors for low bone mineral density (BMD). Physical activity (PA) is a key factor in skeletal health and thus, PA levels might be associated to the risk of developing osteoporosis. Therefore, the aims were (1) to describe PA patterns in adolescen...

journal_title：BMC endocrine disorders

authors： Matute-Llorente A,González-Agüero A,Gómez-Cabello A,Vicente-Rodríguez G,Casajús JA

更新日期：2013-07-04 00:00:00

abstract：BACKGROUND:We report a novel mutation within the StAR gene, causing congenital adrenal hyperplasia, with the so far unreported association with heterochromia iridis. CASE PRESENTATION:In a now 15-year-old girl (born at 41 + 6 weeks of gestation) adrenal failure was diagnosed in the neonatal period based on the clinica...

journal_title：BMC endocrine disorders

authors： Splittstösser V,Schreiner F,Gohlke B,Welzel M,Holterhus PM,Woelfle J

更新日期：2019-10-30 00:00:00

abstract：BACKGROUND:We report the case of a patient who had a non-functional metastatic pancreatic neuroendocrine tumour (pNET), which changed in functionality during the course of the disease. This case demonstrates the effectiveness of conventional cytotoxic chemotherapy in the management of select group of patients with this...

journal_title：BMC endocrine disorders

authors： Rajeev SP,McDougall S,Terlizzo M,Palmer D,Daousi C,Cuthbertson DJ

更新日期：2014-08-24 00:00:00

abstract：BACKGROUND:Benign thyroid nodules (BTN) are frequently diagnosed as papillary thyroid carcinoma (PTC), leading to unnecessary treatment. We found that plasma lncRNA DLG1-AS1 was upregulated in PTC patients but not in BTN patients and healthy controls. METHODS:In this study DLG1-AS1 and miR-199a-3p in plasma of both PT...

journal_title：BMC endocrine disorders

authors： He T,Wang H,Sun J,Wu J,Gong F,Li S,Wang H,Li Y

更新日期：2019-11-12 00:00:00

abstract：BACKGROUND:Diabetes mellitus (DM) is a global health care problem that can impose a substantial economic burden. Diabetic peripheral neuropathy (DPN) is a common microvascular complication of DM that increases the potential for morbidity and disability due to ulceration and amputation. Though there is a significant amo...

journal_title：BMC endocrine disorders

authors： Shiferaw WS,Akalu TY,Work Y,Aynalem YA

更新日期：2020-04-15 00:00:00

abstract：BACKGROUND:Anti-Müllerian hormone (AMH) is now considered the best serum biomarker of ovarian reserve, while basal sex hormones are classic markers used for assessing ovarian reserve. The interaction between AMH and sex hormones are complicated and not sufficiently addressed. In this study, we took diminished ovarian r...

journal_title：BMC endocrine disorders

authors： Lv PP,Jin M,Rao JP,Chen J,Wang LQ,Huang CC,Yang SQ,Yao QP,Feng L,Shen JM,Feng C

更新日期：2020-07-08 00:00:00

abstract：BACKGROUND:The aim of this study is to perform a cost-effectiveness comparison between palpation-guided thyroid fine-needle aspiration biopsies (P-FNA) and ultrasound-guided thyroid FNA biopsies (USG-FNA). METHODS:Each nodule was considered as a case. Diagnostic steps were history and physical examination, TSH measure...

journal_title：BMC endocrine disorders

authors： Can AS

更新日期：2009-05-16 00:00:00

abstract：UNLABELLED: BACKGROUND:Hypoglycaemia is a serious adverse effect of antidiabetic drug therapy. We aimed to determine incidence rates of hypoglycaemia in type-2 diabetic patients and identify predictors of hypoglycaemia when treatment is intensified. METHODS:DiaRegis is a prospective German registry that follows 3810 ...

journal_title：BMC endocrine disorders

authors： Tschöpe D,Bramlage P,Binz C,Krekler M,Deeg E,Gitt AK

更新日期：2012-10-17 00:00:00

abstract：BACKGROUND:Hypoglycemia is a common complication of diabetes treatment. This paper describes symptoms, predecessors, consequences and medications associated with the first episode of severe hypoglycemia among ACCORD participants with type 2 diabetes, and compares these between intensive (Int: goal A1C <6.0%) and standa...

journal_title：BMC endocrine disorders

authors： Bonds DE,Miller ME,Dudl J,Feinglos M,Ismail-Beigi F,Malozowski S,Seaquist E,Simmons DL,Sood A

更新日期：2012-05-30 00:00:00

abstract：BACKGROUND:Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder, and its pathogenesis is still under debate. Trimethylamine-N-oxide (TMAO) is a small, organic compound generated by the gut microbiome with a hypothesized relation to insulin resistance (IR) and low-grade inflammation in PCOS. By compar...

journal_title：BMC endocrine disorders

authors： Huang J,Liu L,Chen C,Gao Y

更新日期：2020-01-06 00:00:00

abstract：BACKGROUND:Adipose tissue abundance relies partly on the factors that regulate adipogenesis, i.e. proliferation and differentiation of adipocytes. While components of the transcriptional program that initiates adipogenesis is well-known, the importance of microRNAs in adipogenesis is less well studied. We thus set out ...

journal_title：BMC endocrine disorders

authors： Keller P,Gburcik V,Petrovic N,Gallagher IJ,Nedergaard J,Cannon B,Timmons JA

更新日期：2011-03-22 00:00:00

abstract：BACKGROUND:There have only been a few reports about use of dipeptidyl peptidase 4 (DPP-4) inhibitors in elderly patients with type 2 diabetes mellitus (T2DM), suggesting that the safety of these agents has not been sufficiently demonstrated. We performed a comparative review of the efficacy and safety of sitagliptin fo...

journal_title：BMC endocrine disorders

authors： Umezawa S,Kubota A,Maeda H,Kanamori A,Matoba K,Jin Y,Minagawa F,Obana M,Iemitsu K,Ito S,Amamiya H,Kaneshiro M,Takai M,Kaneshige H,Hoshino K,Ishikawa M,Minami N,Takuma T,Sasai N,Aoyagi S,Kawata T,Mokubo A,Miyai

更新日期：2015-07-03 00:00:00

abstract：BACKGROUND:A growing body of evidence supports neutrophils as having an active role in the development of diabetic kidney disease (DKD). However, the clinical relevance of neutrophils and DKD in autoimmune diabetes remains unknown. This study aimed to investigate the relationship between circulating neutrophils and DKD...

journal_title：BMC endocrine disorders

authors： Yu Y,Lin Q,Ye D,Wang Y,He B,Li Y,Huang G,Zhou Z,Xiao Y

更新日期：2020-10-22 00:00:00

abstract：BACKGROUND:Non-thyroidal illness syndrome (NTIS) is a characteristic functional constellation of thyrotropic feedback control that frequently occurs in critically ill patients. Although this condition is associated with significantly increased morbidity and mortality, there is still controversy on whether NTIS is cause...

journal_title：BMC endocrine disorders

authors： Dietrich JW,Stachon A,Antic B,Klein HH,Hering S

更新日期：2008-10-13 00:00:00

abstract：BACKGROUND:Promyelocytic leukaemia zinc finger (PLZF) is a transcriptional repressor that was originally isolated from a patient with promyelocytic leukaemia. PLZF also affects key elements for cell cycle progression, such as cyclin A, and can affect the tumourigenicity of various cancers. Thus far, the behaviour of PL...

journal_title：BMC endocrine disorders

authors： Matsuzawa K,Izawa S,Ohkura T,Ohkura H,Ishiguro K,Yoshida A,Takiyama Y,Haneda M,Shigemasa C,Yamamoto K,Taniguchi S

更新日期：2014-07-03 00:00:00

abstract：BACKGROUND:We aimed to explore metabolite biomarkers that could be used to identify pre-diabetes and type 2 diabetes mellitus (T2DM) using systematic review and meta-analysis. METHODS:Four databases, the Cochrane Library, EMBASE, PubMed and Scopus were selected. A random effect model and a fixed effect model were appl...

journal_title：BMC endocrine disorders

authors： Long J,Yang Z,Wang L,Han Y,Peng C,Yan C,Yan D

更新日期：2020-11-23 00:00:00

abstract：BACGROUND:To assess the contribution of macroprolactin to high serum prolactin levels and their association with thyroid status and thyroid autoimmunity during pregnancy. METHODS:138 pregnant women who suspected of having thyroid dysfunction were studied and divided into three groups according to the thyroid status; g...

journal_title：BMC endocrine disorders

authors： Guclu M,Cander S,Kiyici S,Vatansever E,Hacihasanoğlu AB,Kisakol G

更新日期：2015-06-20 00:00:00

abstract：BACKGROUND:Pituitary disorders following pregnancy are an important yet under reported clinical entity in the developing world. Conversely, post partum panhypopituitarism has a more devastating impact on women in such settings due to high fertility rates, poor obstetric care and scarcity of diagnostic and therapeutic r...

journal_title：BMC endocrine disorders

authors： Sheriff FG,Howlett WP,Kilonzo KG

更新日期：2012-07-10 00:00:00

abstract：BACKGROUND:The nonthyroidal illness syndrome (NTIS) is prevalent among patients with enterocutaneous fistula and is associated with poor outcomes. The present study aimed to explore the role of enteral nutrition (EN) therapy on thyroid function among patients with enterocutaneous fistula and NTIS. METHODS:We conducted...

journal_title：BMC endocrine disorders

authors： Li R,Ren J,Wu Q,Wang G,Wu X,Chen J,Li G,Hong Z,Ren H,Zhao Y,Li J

更新日期：2015-11-04 00:00:00