Effects of recreational soccer in men with prostate cancer undergoing androgen deprivation therapy: study protocol for the 'FC Prostate' randomized controlled trial.

abstract：BACKGROUND:Migration is important for the metastatic capacity and thus for the malignancy of cancer cells. There is limited knowledge on regulatory factors that promote the migration of neuroblastoma cells. This study investigates the hypothesis that protein kinase C (PKC) isoforms regulate neuroblastoma cell motility....

journal_title：BMC cancer

authors： Stensman H,Larsson C

更新日期：2008-12-11 00:00:00

abstract：BACKGROUND:For decades, planar bone scintigraphy has been the standard practice for detection of bone metastases in prostate cancer and has been endorsed by recent oncology/urology guidelines. It is a sensitive method with modest specificity. (18)F-fluoride positron emission tomography/computed tomography has shown imp...

journal_title：BMC cancer

authors： Fonager RF,Zacho HD,Langkilde NC,Petersen LJ

更新日期：2016-01-11 00:00:00

abstract：BACKGROUND:There are large ethnic differences in cervical cancer survival in New Zealand that are only partly explained by stage at diagnosis. We investigated the association of comorbidity with cervical cancer survival, and whether comorbidity accounted for the previously observed ethnic differences in survival. METH...

journal_title：BMC cancer

authors： Brewer N,Borman B,Sarfati D,Jeffreys M,Fleming ST,Cheng S,Pearce N

更新日期：2011-04-12 00:00:00

abstract：BACKGROUND:Choriocarcinoma is a gestational trophoblastic tumor which causes high mortality if left untreated. MicroRNAs (miRNAs) are small non protein-coding RNAs which inhibit target gene expression. The role of miRNAs in choriocarcinoma, however, is not well understood. In this study, we examined the effect of miR-3...

journal_title：BMC cancer

authors： Pang RT,Leung CO,Lee CL,Lam KK,Ye TM,Chiu PC,Yeung WS

更新日期：2013-01-18 00:00:00

abstract：BACKGROUND:It is known that amino acid oxidation is increased in tumor-bearing rat muscles and that leucine is an important ketogenic amino acid that provides energy to the skeletal muscle. METHODS:To evaluate the effects of a leucine supplemented diet on the intestinal absorption alterations produced by Walker 256, g...

journal_title：BMC cancer

authors： Ventrucci G,de Mello MA,Gomes-Marcondes MC

更新日期：2002-04-15 00:00:00

abstract：BACKGROUND:The etiological factor for intrahepatic cholangiocarcinoma (ICC) is not clear. Although it has been widely accepted that intrahepatic biliary tree stone is associated with increased risk of ICC, the role of extrahepatic biliary tree stone in the incidence of ICC is controversial. In the present study we aim ...

journal_title：BMC cancer

authors： Cai H,Kong WT,Chen CB,Shi GM,Huang C,Shen YH,Sun HC

更新日期：2015-11-02 00:00:00

abstract：BACKGROUND:The cytochrome P450 (CYP) enzymes 2C19, 2D6, and 3A5 are responsible for converting the selective estrogen receptor modulator (SERM), tamoxifen to its active metabolites 4-hydroxy-tamoxifen (4OHtam) and 4-hydroxy-N-demethyltamoxifen (4OHNDtam, endoxifen). Inter-individual variations of the activity of these ...

journal_title：BMC cancer

authors： Gjerde J,Geisler J,Lundgren S,Ekse D,Varhaug JE,Mellgren G,Steen VM,Lien EA

更新日期：2010-06-21 00:00:00

abstract：BACKGROUND:Metastasis is the main cause of death for lung cancer patients. The ex vivo 4D acellular lung model has been shown to mimic this metastatic process. However, the main concern is the model's lack of cellular components of the tumor's microenvironment. In this study, we aim to determine if the intact lung micr...

journal_title：BMC cancer

authors： Mishra DK,Miller RA,Pence KA,Kim MP

更新日期：2018-04-18 00:00:00

abstract：BACKGROUND:Epidermal growth factor receptor exon 20 insertion (EGFRex20ins) mutations represent approximately 4-12% of EGFR mutations and are generally refractory to the 1st and 2nd generation EGFR tyrosine kinase inhibitors (TKIs). Development of effective therapies for patients with EGFRex20ins mutant non-small-cell ...

journal_title：BMC cancer

authors： Fang W,Huang Y,Hong S,Zhang Z,Wang M,Gan J,Wang W,Guo H,Wang K,Zhang L

更新日期：2019-06-17 00:00:00

abstract：BACKGROUND:CD133 (prominin-1) is widely believed to be a cancer stem cell marker in various solid tumor types, and CD133 has been correlated with tumor-initiating capacity. Recently, the nuclear location of CD133 expression in tumors has been discussed, but hepatocellular carcinoma (HCC) has not been included in these ...

journal_title：BMC cancer

authors： Chen YL,Lin PY,Ming YZ,Huang WC,Chen RF,Chen PM,Chu PY

更新日期：2017-07-07 00:00:00

abstract：BACKGROUND:Long non-coding RNAs have been shown to have critical regulatory roles in cancer biology. However, the contributions of lncRNAs to gastric cancer remain largely unknown. METHODS:The differential expression of lncRNAs in gastric cancer and paired non-cancerous tissues were identified by microarray and valida...

journal_title：BMC cancer

authors： Han Y,Ye J,Wu D,Wu P,Chen Z,Chen J,Gao S,Huang J

更新日期：2014-12-11 00:00:00

abstract：BACKGROUND:Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) represent a heterogenous group of tumors. Findings from the phase III NETTER-1 trial showed that treatment of unresectable/metastatic progressive gastrointestinal (GI) NETs with 177Lu-Dotatate resulted in a significant improvement in progression-free su...

journal_title：BMC cancer

authors： Smith-Palmer J,Leeuwenkamp OR,Virk J,Reed N

更新日期：2021-01-05 00:00:00

abstract：BACKGROUND:Mutations in the activation segment of the v-raf murine sarcoma viral oncogene homolog B (BRAF) gene are present in approximately 50% of melanomas. The selective BRAF inhibitor vemurafenib has demonstrated significant clinical benefits in patients with melanomas harboring the most common mutations (V600E, V6...

journal_title：BMC cancer

authors： Trudel S,Odolczyk N,Dremaux J,Toffin J,Regnier A,Sevestre H,Zielenkiewicz P,Arnault JP,Gubler B

更新日期：2014-09-29 00:00:00

abstract：BACKGROUND:The retroperitoneal margin is frequently microscopically tumour positive in non-curative periampullary adenocarcinoma resections. This margin should be evaluated by serial perpendicular sectioning. The aim of the study was to determine whether retroperitoneal margin involvement independently predicts surviva...

journal_title：BMC cancer

authors： Westgaard A,Tafjord S,Farstad IN,Cvancarova M,Eide TJ,Mathisen O,Clausen OP,Gladhaug IP

更新日期：2008-01-14 00:00:00

abstract：BACKGROUND:Compared with World Health Organization-defined acute myeloid leukaemia (AML) not otherwise specified, patients with AML with myelodysplasia-related changes (AML-MRC) are generally older and more likely to have poor-risk cytogenetics, leading to poor response and prognosis. More than one-half of all older (≥...

journal_title：BMC cancer

authors： Seymour JF,Döhner H,Butrym A,Wierzbowska A,Selleslag D,Jang JH,Kumar R,Cavenagh J,Schuh AC,Candoni A,Récher C,Sandhu I,Del Castillo TB,Al-Ali HK,Falantes J,Stone RM,Minden MD,Weaver J,Songer S,Beach CL,Dombret H

更新日期：2017-12-14 00:00:00

abstract：BACKGROUND:Bevacizumab, an antibody neutralizing Vascular Endothelial Growth Factor (VEGF), is licensed for the management of patients with advanced colon cancer. However, tumor biomarkers identifying the molecular tumor subsets most amenable to angiogenesis modulation are lacking. METHODS:We profiled expession of 245...

journal_title：BMC cancer

authors： Pentheroudakis G,Kotoula V,Fountzilas E,Kouvatseas G,Basdanis G,Xanthakis I,Makatsoris T,Charalambous E,Papamichael D,Samantas E,Papakostas P,Bafaloukos D,Razis E,Christodoulou C,Varthalitis I,Pavlidis N,Fountzilas G

更新日期：2014-02-20 00:00:00

abstract：BACKGROUND:Cell-surface glycoproteins play critical roles in cell-to-cell recognition, signal transduction and regulation, thus being crucial in cell proliferation and cancer etiogenesis and development. DPP IV and NEP are ubiquitous glycopeptidases closely linked to tumor pathogenesis and development, and they are use...

journal_title：BMC cancer

authors： Varona A,Blanco L,Perez I,Gil J,Irazusta J,López JI,Candenas ML,Pinto FM,Larrinaga G

更新日期：2010-05-11 00:00:00

abstract：BACKGROUND:While data from several studies over the last decade has demonstrated that introduction of immunologic checkpoint blockage therapy with anti-CTLA-4/PD-1 drugs leads to improved survival in metastatic melanoma patients, relatively little is known about brain-specific therapeutic response and adverse events in...

journal_title：BMC cancer

authors： McDonald MA,Sanghvi P,Bykowski J,Daniels GA

更新日期：2018-05-09 00:00:00

abstract：BACKGROUND:Aspirin (ASA) use has been associated with improved breast cancer survival in several prospective studies. METHODS:We conducted a nested case-control study of ASA use after a breast cancer diagnosis among women using Swedish National Registries. We assessed prospectively recorded ASA exposure during several...

journal_title：BMC cancer

authors： Holmes MD,Olsson H,Pawitan Y,Holm J,Lundholm C,Andersson TM,Adami HO,Askling J,Smedby KE

更新日期：2014-06-02 00:00:00

abstract：BACKGROUND:Being the most common cancer among women worldwide, it is vital to be well-aware of breast cancer risk factors, symptoms and curability. However, few studies have reported breast cancer literacy in students using a validated instrument. METHODS:A cross-sectional study was conducted among students of grades ...

journal_title：BMC cancer

authors： Bhandari PM,Thapa K,Dhakal S,Bhochhibhoya S,Deuja R,Acharya P,Mishra SR

更新日期：2016-02-18 00:00:00

abstract：BACKGROUND:Heterogeneous nuclear ribonucleoproteins (hnRNPs) of the A/B type (hnRNP A1, A2/B1, A3) are highly related multifunctional proteins participating in alternative splicing by antagonising other splicing factors, notably ASF/SF2. The altered expression pattern of hnRNP A2/B1 and/or splicing variant B1 alone in ...

journal_title：BMC cancer

authors： Boukakis G,Patrinou-Georgoula M,Lekarakou M,Valavanis C,Guialis A

更新日期：2010-08-17 00:00:00

abstract：BACKGROUND:Patients suffering from squamous cell carcinoma of the larynx (LSCC) with lymphatic metastasis have a relatively poor prognosis and often require radical therapeutic management. The mechanisms which drive metastasis to the lymph nodes are largely unknown but may be promoted by a pro-angiogenic tumor microenv...

journal_title：BMC cancer

authors： Schlüter A,Weller P,Kanaan O,Nel I,Heusgen L,Höing B,Haßkamp P,Zander S,Mandapathil M,Dominas N,Arnolds J,Stuck BA,Lang S,Bankfalvi A,Brandau S

更新日期：2018-03-09 00:00:00

abstract：BACKGROUND:Acute myeloid leukemia (AML) is predominantly a disease of older patients with a poor long-term survival. Approval of decitabine (DAC) in the European Union (EU) in 2012 for the treatment of patients with AML ≥65 years marks the potential for hypomethylating agents in elderly AML. Nevertheless the situation ...

journal_title：BMC cancer

authors： Grishina O,Schmoor C,Döhner K,Hackanson B,Lubrich B,May AM,Cieslik C,Müller MJ,Lübbert M

更新日期：2015-05-26 00:00:00

abstract：BACKGROUND:Small cell cervical carcinoma (SCCC) is a rare, aggressive tumor with a poor prognosis. However, information in relation to its treatment is scarce due to the limited numbers of patients. The aim of this study was to establish whether platinum-based combination chemotherapy may by beneficial in this patient ...

journal_title：BMC cancer

authors： Huang L,Liao LM,Liu AW,Wu JB,Cheng XL,Lin JX,Zheng M

更新日期：2014-02-27 00:00:00

abstract：BACKGROUND:Circulating tumor cells (CTCs) are detectable in peripheral blood of metastatic breast cancer patients (MBC). In this paper we evaluate a new CTC separation method based on a combination of anti-EpCAM- and anti-cytokeratin magnetic cell separation with the aim to improve CTC detection with low target antigen...

journal_title：BMC cancer

authors： Weissenstein U,Schumann A,Reif M,Link S,Toffol-Schmidt UD,Heusser P

更新日期：2012-05-30 00:00:00

abstract：BACKGROUND:Ethyl carbamate (EC) is a multi-site carcinogen in experimental animals and probably carcinogenic to humans (IARC group 2A). Traces of EC below health-relevant ranges naturally occur in several fermented foods and beverages, while higher concentrations above 1 mg/l are regularly detected in only certain spir...

journal_title：BMC cancer

authors： Lachenmeier DW,Lima MC,Nóbrega IC,Pereira JA,Kerr-Corrêa F,Kanteres F,Rehm J

更新日期：2010-06-08 00:00:00

abstract：BACKGROUND:Overweight and weight gain throughout adult life have been associated with increased risk of breast cancer after the menopause. However the role of body weight at a young age and of the timing of weight gain over the lifetime in postmenopausal breast cancer is not well documented. METHODS:We conducted a pop...

journal_title：BMC cancer

authors： Cordina-Duverger E,Truong T,Anger A,Sanchez M,Arveux P,Kerbrat P,Guénel P

更新日期：2016-09-29 00:00:00

abstract：BACKGROUND:Circular RNAs (circRNAs) have emerged as a novel category of non-coding RNA, which exhibit a pivotal effect on regulating gene expression and biological functions, yet how circRNAs function in osteosarcoma (OSA) still demands further investigation. This study aimed at probing into the function of hsa_circ_00...

journal_title：BMC cancer

authors： Li H,He L,Tuo Y,Huang Y,Qian B

更新日期：2020-10-23 00:00:00

abstract：BACKGROUND:The development of targeted therapies has undoubtedly broadened therapeutic options for patients with colorectal cancer (CRC). The use of bevacizumab to reduce angiogenesis has been associated with improved clinical outcomes. However, an urgent need for prognostic/predictive biomarkers for anti-angiogenic th...

journal_title：BMC cancer

authors： Paiva TF Jr,de Jesus VH,Marques RA,da Costa AA,de Macedo MP,Peresi PM,Damascena A,Rossi BM,Begnami MD,de Lima VC

更新日期：2015-09-22 00:00:00

abstract：BACKGROUND:Lymphotoxin-alpha (LTA) is a pro-inflammatory cytokine with anti-tumor activity. The objective of this study was to determine whether LTA polymorphisms influence the presence of cancer. METHODS:LTA polymorphisms C804A (rs1041981, T60N) and T495C (rs2229094, C13R) were determined in 1,536 consecutive autopsy...

journal_title：BMC cancer

authors： Takei K,Ikeda S,Arai T,Tanaka N,Muramatsu M,Sawabe M

更新日期：2008-08-13 00:00:00