Weight and weight changes throughout life and postmenopausal breast cancer risk: a case-control study in France.

abstract：BACKGROUND:The goal of this exploratory study was to develop and assess a prediction model which can potentially be used as a biomarker of breast cancer, based on anthropometric data and parameters which can be gathered in routine blood analysis. METHODS:For each of the 166 participants several clinical features were ...

journal_title：BMC cancer

authors： Patrício M,Pereira J,Crisóstomo J,Matafome P,Gomes M,Seiça R,Caramelo F

更新日期：2018-01-04 00:00:00

abstract：BACKGROUND:Microvascular invasion (MVI) is recognized as a prognostic factor associated with poor outcome in hepatocellular carcinoma (HCC) patients after curative resection. It remains unclear, however, whether MVI can provide prognostic information for patients at a specific tumor stage. METHODS:Consecutive HCC pati...

journal_title：BMC cancer

authors： Huang C,Zhu XD,Ji Y,Ding GY,Shi GM,Shen YH,Zhou J,Fan J,Sun HC

更新日期：2017-01-17 00:00:00

abstract：:It has been highlighted that in the original manuscript [1] Table S3 'An example of the predictive computational modeling process. Specific details on an annexure section of the PD-L1 pathway show the step-by-step reactions, mechanisms, and reaction equations that occur. Such reactions also occurred in all of the othe...

journal_title：BMC cancer

authors： Brogden KA,Parashar D,Hallier AR,Braun T,Qian F,Rizvi NA,Bossler AD,Milhem MM,Chan TA,Abbasi T,Vali S

更新日期：2018-04-12 00:00:00

abstract：BACKGROUND:New disease mapping techniques widely used in small-area studies enable disease distribution patterns to be identified and have become extremely popular in the field of public health. This paper reports on trends in the geographical mortality patterns of the most frequent cancers in Spain, over a period of 2...

journal_title：BMC cancer

authors： López-Abente G,Aragonés N,Pérez-Gómez B,Pollán M,García-Pérez J,Ramis R,Fernández-Navarro P

更新日期：2014-07-24 00:00:00

abstract：BACKGROUND:Gynecologic cancer is one of the most common malignant diseases in working-age women. This study investigated whether several characteristics influence return to work after treatment of gynecologic cancer. METHODS:We investigated the correlations between return to work and several other characteristics in 1...

journal_title：BMC cancer

authors： Nakamura K,Masuyama H,Nishida T,Haraga J,Ida N,Saijo M,Haruma T,Kusumoto T,Seki N,Hiramatsu Y

更新日期：2016-07-29 00:00:00

abstract：BACKGROUND:Anaplastic thyroid cancer (ATC) is one of the most aggressive of all solid tumors for which no effective therapies are currently available. Oncolytic Newcastle disease virus (NDV) has shown the potential to induce oncolytic cell death in a variety of cancer cells of diverse origins. However, whether oncolyti...

journal_title：BMC cancer

authors： Jiang K,Song C,Kong L,Hu L,Lin G,Ye T,Yao G,Wang Y,Chen H,Cheng W,Barr MP,Liu Q,Zhang G,Ding C,Meng S

更新日期：2018-07-18 00:00:00

abstract：BACKGROUND:Mutations activating the α subunit of heterotrimeric Gs protein are associated with a number of highly specific pathological molecular phenotypes. One of the best characterized is the McCune Albright syndrome. The disease presents with an increased incidence of neoplasias in specific tissues. MAIN BODY:A si...

journal_title：BMC cancer

authors： Innamorati G,Wilkie TM,Kantheti HS,Valenti MT,Dalle Carbonare L,Giacomello L,Parenti M,Melisi D,Bassi C

更新日期：2018-03-15 00:00:00

abstract：BACKGROUNDS:Cancer stem cell (CSC) research has highlighted the necessity of developing drugs targeting CSCs. We investigated a hepatocellular carcinoma (HCC) cell line that not only has CSC hierarchy but also shows phenotypic changes (population changes) upon differentiation of CSC during culture and can be used for s...

journal_title：BMC cancer

authors： Yamada T,Abei M,Danjoh I,Shirota R,Yamashita T,Hyodo I,Nakamura Y

更新日期：2015-04-11 00:00:00

abstract：BACKGROUND:Breast cancer is the most common form of malignancy affecting women worldwide. It is also the leading cancer in females in Cyprus, with approximately 400 new cases diagnosed annually. It is well recognized that genetic variation as well as environmental factors modulate breast cancer risk. The main aim of th...

journal_title：BMC cancer

authors： Hadjisavvas A,Loizidou MA,Middleton N,Michael T,Papachristoforou R,Kakouri E,Daniel M,Papadopoulos P,Malas S,Marcou Y,Kyriacou K

更新日期：2010-08-23 00:00:00

abstract：BACKGROUND:The prognostic significance of FOXP3+ tumor-infiltrating lymphocytes (TILs) in patients with breast cancer remains controversial. The aims of our meta-analysis are to evaluate its association with clinicopathological characteristics and prognostic significance in patients with breast cancer. METHODS:PubMed,...

journal_title：BMC cancer

authors： Jiang D,Gao Z,Cai Z,Wang M,He J

更新日期：2015-10-17 00:00:00

abstract：BACKGROUND:Disorders of cell adhesion are critical steps in cancer progression in which varieties of markers including cadherins are involved in.Btbd7 was found to inhibit E-cadherin expression in MDCK cells and play important roles during branching morphogenesis of embryonic salivary glands and lungs. However its func...

journal_title：BMC cancer

authors： Fan C,Miao Y,Zhang X,Liu D,Jiang G,Lin X,Han Q,Luan L,Xu Z,Wang E

更新日期：2014-09-24 00:00:00

abstract：BACKGROUND:The literature on sexual orientation disclosure is arguably one of the most developed in the field of lesbian, gay and bisexual (LGB) people in healthcare in English speaking countries however, relatively little research has been conducted into disclosure in cancer care. Studies have been mainly undertaken i...

journal_title：BMC cancer

authors： Fish J,Williamson I,Brown J

更新日期：2019-07-10 00:00:00

abstract：BACKGROUND:Biannual ultrasound (US)-with or without alpha-fetoprotein (AFP)-is recommended by current guidelines for the surveillance of hepatocellular carcinoma (HCC). However, the inadequate sensitivity of US has been a concern. Magnetic resonance imaging (MRI) is known to have high sensitivity in detecting hepatic m...

journal_title：BMC cancer

authors： An C,Kim DY,Choi JY,Han KH,Roh YH,Kim MJ

更新日期：2018-09-24 00:00:00

abstract：BACKGROUND:Genetic counselling and testing for Lynch syndrome (LS) have recently been introduced in several Latin America countries. We aimed to characterize the clinical, molecular and mismatch repair (MMR) variants spectrum of patients with suspected LS in Latin America. METHODS:Eleven LS hereditary cancer registrie...

journal_title：BMC cancer

authors： Rossi BM,Palmero EI,López-Kostner F,Sarroca C,Vaccaro CA,Spirandelli F,Ashton-Prolla P,Rodriguez Y,de Campos Reis Galvão H,Reis RM,Escremim de Paula A,Capochin Romagnolo LG,Alvarez K,Della Valle A,Neffa F,Kalfayan PG,Spir

更新日期：2017-09-05 00:00:00

abstract：BACKGROUND:Platelet to Lymphocyte ratio (PLR) is thought to be associated with a worse outcome in multiple types of cancer. However, the prognostic significance of PLR has not been investigated in the prostate cancer (PCa) patients receiving hormonal therapy. The objective of this study was to determine the prognostic ...

journal_title：BMC cancer

authors： Wang Y,Xu F,Pan J,Zhu Y,Shao X,Sha J,Wang Z,Cai Y,Liu Q,Dong B,Xue W,Huang Y

更新日期：2016-05-24 00:00:00

abstract：BACKGROUND:The care itinerary for cancer involves difficulties that occur in several different areas, whether in the diagnostic procedures, in surgery, or in adjuvant treatment. The aim of this work was to obtain a valid instrument measuring satisfaction among patients with breast cancer and exploring their care itiner...

journal_title：BMC cancer

authors： Defossez G,Mathoulin-Pelissier S,Ingrand I,Gasquet I,Sifer-Riviere L,Ingrand P,Salamon R,Migeot V,REPERES research network.

更新日期：2007-07-16 00:00:00

abstract：BACKGROUND:Genomic alterations of the proto-oncogene c-erbB-2 (HER-2/neu) are associated with aggressive behavior and poor prognosis in patients with breast cancer. The variable clinical outcomes seen in patients with similar HER2 status, given similar treatments, suggests that the effects of amplification of HER2 can ...

journal_title：BMC cancer

authors： Ellsworth RE,Ellsworth DL,Patney HL,Deyarmin B,Love B,Hooke JA,Shriver CD

更新日期：2008-10-14 00:00:00

abstract：BACKGROUND:Adoptive immunotherapy with cytotoxic T lymphocytes (CTL) represents an alternative approach to treating solid tumors. Ideally, this would confer long-term protection against tumor. We previously demonstrated that in vitro-generated tumor-specific CTL from the ovalbumin (OVA)-specific OT-I T cell receptor tr...

journal_title：BMC cancer

authors： Bathe OF,Dalyot-Herman N,Malek TR

更新日期：2003-07-28 00:00:00

abstract：BACKGROUND:Oncolytic viruses represent a promising therapy against cancers with acquired drug resistance. However, low efficacy limits its clinical application. The objective of this study is to investigate whether pharmacologically modulating autophagy could enhance oncolytic Newcastle disease virus (NDV) strain NDV/F...

journal_title：BMC cancer

authors： Jiang K,Li Y,Zhu Q,Xu J,Wang Y,Deng W,Liu Q,Zhang G,Meng S

更新日期：2014-07-30 00:00:00

abstract：BACKGROUND:Outpatient autologous stem cell transplantations (ASCTs) in multiple myeloma and lymphoma patients have been shown to reduce the overall costs and improve the quality of life relative to inpatient ASCTs. This systematic review and meta-analysis was performed with the aim of comprehensively comparing the risk...

journal_title：BMC cancer

authors： Owattanapanich W,Suphadirekkul K,Kunacheewa C,Ungprasert P,Prayongratana K

更新日期：2018-11-16 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are small non-coding RNAs involved in post-transcriptional gene expression regulation and have been described as key regulators of carcinogenesis. Aberrant miRNA expression has been frequently reported in sporadic breast cancers, but few studies have focused on profiling hereditary breast ...

journal_title：BMC cancer

authors： Pessôa-Pereira D,Evangelista AF,Causin RL,da Costa Vieira RA,Abrahão-Machado LF,Santana IVV,da Silva VD,de Souza KCB,de Oliveira-Silva RJ,Fernandes GC,Reis RM,Palmero EI,Marques MMC

更新日期：2020-02-22 00:00:00

abstract：BACKGROUND:Breast metastasis from lung cancer has been reported, but not from SCLC that is transformed from lung adenocarcinoma during maintenance treatment with epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). Transformation to small cell lung cancer(SCLC), although uncommonly seen, has been asso...

journal_title：BMC cancer

authors： Lin Q,Cai GP,Yang KY,Yang L,Chen CS,Li YP

更新日期：2016-08-03 00:00:00

abstract：BACKGROUND:FMS-like tyrosine kinase 3 (FLT3) is a commonly mutated protein in a variety of human acute leukemias. Mutations leading to constitutively active FLT3, including internal tandem duplications of the juxtamembrane domain (ITD), result in continuous cellular proliferation, resistance to apoptotic cell death, an...

journal_title：BMC cancer

authors： Suter SE,Small GW,Seiser EL,Thomas R,Breen M,Richards KL

更新日期：2011-01-27 00:00:00

abstract：BACKGROUND:Omega-3 polyunsaturated fatty acids (PUFAs) were proposed to have potential effects against inflammation and cancer. However, results from epidemiology studies remain inconsistent. We aimed to explore the associations of plasma PUFAs with EC recurrence and all-cause mortality. METHOD:Women diagnosed with en...

journal_title：BMC cancer

authors： Li P,Shan B,Jia K,Hu F,Xiao Y,Zheng J,Gao YT,Wang H,Gao Y

更新日期：2020-06-20 00:00:00

abstract：BACKGROUND:Hypoxia is often encountered in solid tumors and known to contribute to aggressive tumor behavior, radiation- and chemotherapy resistance resulting in a poor prognosis for the cancer patient. MicroRNAs (miRNAs) play a role in the regulation of the tumor cell response to hypoxia, however, not much is known ab...

journal_title：BMC cancer

authors： Gits CM,van Kuijk PF,de Rijck JC,Muskens N,Jonkers MB,van IJcken WF,Mathijssen RH,Verweij J,Sleijfer S,Wiemer EA

更新日期：2014-06-13 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) is a disease that can be prevented through early detection. Through the use of effective educational tools, individuals can become better informed about CRC and understand the importance of screening and early detection. The walk through Inflatable Colon is an innovative educational r...

journal_title：BMC cancer

authors： Sanchez JI,Palacios R,Cole A,O'Connell MA

更新日期：2014-08-28 00:00:00

abstract：BACKGROUND:The metastasis-promoting protein S100A4 induces expression of ephrin-A1 and osteopontin in osteosarcoma cell lines. The aim of this study was to investigate S100A4-mediated stimulation of ephrin-A1 and osteopontin in non-small cell lung cancer (NSCLC) cell lines, and to characterize the expression of these b...

journal_title：BMC cancer

authors： Rud AK,Lund-Iversen M,Berge G,Brustugun OT,Solberg SK,Mælandsmo GM,Boye K

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Nitric oxide (NO) and its oxidative reaction products have been repeatedly shown to block steroid receptor function via nitrosation of zinc finger structures in the DNA-binding domain (DBD). In consequence NO-donors could be of special interest for the treatment of deregulated androgen receptor(AR)-signaling...

journal_title：BMC cancer

authors： Laschak M,Spindler KD,Schrader AJ,Hessenauer A,Streicher W,Schrader M,Cronauer MV

更新日期：2012-03-30 00:00:00

abstract：BACKGROUND:Recent reports indicate the existence of breast cancer cells expressing very high levels of the Arylhydrocarbon receptor (AhR), a ubiquitous intracellular receptor best known for mediating toxic action of dioxin and related pollutants. Positive correlation between the degree of AhR overexpression and states ...

journal_title：BMC cancer

authors： Wong PS,Li W,Vogel CF,Matsumura F

更新日期：2009-07-15 00:00:00

abstract：BACKGROUND:Germline mutations in the DNA mismatch repair genes predispose to Lynch syndrome, thus conferring a high relative risk of colorectal and endometrial cancer. The MLH1, MSH2 and MSH6 mutational spectrum reported so far involves minor alterations scattered throughout their coding regions as well as large genomi...

journal_title：BMC cancer

authors： Thodi G,Fostira F,Sandaltzopoulos R,Nasioulas G,Grivas A,Boukovinas I,Mylonaki M,Panopoulos C,Magic MB,Fountzilas G,Yannoukakos D

更新日期：2010-10-11 00:00:00