Comparison of osteoprotegerin and vascular endothelial growth factor in normoalbuminuric Type 1 diabetic and control subjects.

abstract：:Adolescent girls with a history of premature pubarche have an increased incidence of functional ovarian hyperandrogenism [a form of polycystic ovary syndrome (PCOS)] at adolescence, which is usually associated with hyperinsulinemia and dyslipemia. The hyperinsulinemia and lipid disturbances can often be detected in th...

journal_title：Journal of endocrinological investigation

authors： Ibáñez L,de Zegher F,Potau N

更新日期：1998-10-01 00:00:00

abstract：:This study was performed to determine whether phenotypically healthy sisters of women with polycystic ovary syndrome (PCOS) have evidence of insulin resistance. We studied 54 women: 17 with PCOS, 17 sisters of these probands and 20 control women with similar age, body mass index (BMI) and waist-to-hip ratio (WHR). The...

journal_title：Journal of endocrinological investigation

authors： Diamanti-Kandarakis E,Alexandraki K,Bergiele A,Kandarakis H,Mastorakos G,Aessopos A

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:The Merseburg triad (hyperthyroidism, goiter, and orbitopathy) characterizes classical description of Graves' disease (GD). Aim of this observational, longitudinal study was to evaluate the current clinical features of newly diagnosed GD in Italy. MATERIALS AND METHODS:In two Northern Italy centers (Varese a...

journal_title：Journal of endocrinological investigation

authors： Bartalena L,Masiello E,Magri F,Veronesi G,Bianconi E,Zerbini F,Gaiti M,Spreafico E,Gallo D,Premoli P,Piantanida E,Tanda ML,Ferrario M,Vitti P,Chiovato L

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:To our knowledge, no case of remission in autoimmune Addison's disease has previously been reported. We describe a patient with primary adrenal insufficiency caused by autoimmune adrenalitis in whom partial remission was observed after 7 yr. CASE:A 39-yr-old male was referred because of extreme fatigue, weig...

journal_title：Journal of endocrinological investigation

authors： Smans LC,Zelissen PM

更新日期：2008-07-01 00:00:00

abstract：:Thyroid diseases may lead to endothelial dysfunction; however, the mechanism underlying the endothelial dysfunction in thyroid disease is not clear yet. Asymmetric dimethylarginine (ADMA), a novel inhibitor of endothelial nitric oxide synthase (eNOS), blocks nitric oxide (NO) synthesis from L-arginine. Symmetric dimet...

journal_title：Journal of endocrinological investigation

authors： Arikan E,Karadag CH,Guldiken S

更新日期：2007-03-01 00:00:00

abstract：:The aim of the study was to determine the main metabolic parameters of 11-beta-hydroxy-androstenedione (11 OHAD) in man. Seven normal subjects were investigated at 1-3 months interval by 2 types of isotope dilution techniques using a tritiated tracer: constant infusion and bolus iv injection. 3H-11 OHAD and 3H-11-beta...

journal_title：Journal of endocrinological investigation

authors： Lejeune-Lenain C,Courtois P,Art G,Franckson JR

更新日期：1984-12-01 00:00:00

abstract：:Obesity is associated with a number of serious diseases and with a degree of motor disability, but the extent of the risk and functional derangement within the obese population is not yet completely defined. The study aims to evaluate the combined effect of degree of adiposity, body fat distribution and age on selecte...

journal_title：Journal of endocrinological investigation

authors： Lafortuna CL,Agosti F,Proietti M,Adorni F,Sartorio A

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Neonatal hypothyroidism has serious effects on growth, development, and metabolism. AIM:This study aims to investigate the effects of the neonatal hypothyroidism on carbohydrate metabolism, islet insulin secretion and morphology of the pancreatic islets in adult male offspring. MATERIALS/SUBJECTS AND METHO...

journal_title：Journal of endocrinological investigation

authors： Farahani H,Ghasemi A,Roghani M,Zahediasl S

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:To investigate the effect of testosterone treatment on biomarkers calprotectin, fibroblast growth factor 23 (FGF23), soluble Klotho, phosphate, calcium, parathyroid hormone, creatinine and estimated glomerular filtration rate. DESIGN:Randomized, double-blinded, placebo-controlled study. SETTING:Odense Andr...

journal_title：Journal of endocrinological investigation

authors： Pedersen L,Christensen LL,Pedersen SM,Andersen M

更新日期：2017-05-01 00:00:00

abstract：:Long-acting im bromocriptine was administered to 7 patients with pituitary macroadenomas (4 acromegalics, 1 Nelson's syndrome and 2 prolactinomas), with good tolerance except during the first 24 h. During a 42-day period hormonal, CT-scan and visual field variations were followed. In acromegalics HGH decrease was not ...

journal_title：Journal of endocrinological investigation

authors： Halperin I,Rodriguez MD,Cardenal C,Casamitjana R,Martinez Osaba MJ,Lienas V,Vilardell E

更新日期：1987-06-01 00:00:00

abstract：:Whole-body vibration is reported to increase muscle performance, bone mineral density and stimulate the secretion of lipolytic and protein anabolic hormones, such as GH and testosterone, that might be used for the treatment of obesity. To date, as no controlled trial has examined the effects of vibration exercise on t...

journal_title：Journal of endocrinological investigation

authors： Di Loreto C,Ranchelli A,Lucidi P,Murdolo G,Parlanti N,De Cicco A,Tsarpela O,Annino G,Bosco C,Santeusanio F,Bolli GB,De Feo P

更新日期：2004-04-01 00:00:00

abstract：:Disulfide bonds are formed between the sulfhydryl groups in two cysteine residues of a protein. The formation of these bonds is necessary for the proper folding of a protein into its active three-dimensional form. In this study, the genes associated with disulfide bond formation of proteins from the rat thyroid cell l...

journal_title：Journal of endocrinological investigation

authors： Park S,Hwang I,Shong M,Kwon OY

更新日期：2003-02-01 00:00:00

abstract：:Iodine balance during pregnancy and lactation was investigated by measuring iodine concentration in the urine of 11 pregnant women, born and living in a moderately iodine deficient endemic goiter area in Northeastern Sicily, collected during the last week of pregnancy, and between the 5th and 7th day after delivery, a...

journal_title：Journal of endocrinological investigation

authors： Vermiglio F,Lo Presti VP,Finocchiaro MD,Battiato S,Grasso L,Ardita FV,Mancuso A,Trimarchi F

更新日期：1992-02-01 00:00:00

abstract：:Up to now, the diagnosis of silent corticotroph cell pituitary adenomas has been made only on histopathological basis. In this paper we describe 6 women affected with pituitary adenomas, without evident clinical features of hypercortisolism, in whom retrospective data suggested the possibility of clinically diagnosing...

journal_title：Journal of endocrinological investigation

authors： Ambrosi B,Colombo P,Bochicchio D,Bassetti M,Masini B,Faglia G

更新日期：1992-06-01 00:00:00

abstract：:Aim of the study was to compare urinary galactosyl-hydroxylysine (GHyl), deoxypyridinoline (D-Pyr) and pyridinoline (Pyr) before and after 5 to 9 months of hormone replacement therapy (HRT) in postmenopausal women. The urinary markers were measured by HPLC in the second void of fasting samples and were expressed as ra...

journal_title：Journal of endocrinological investigation

authors： Marabini R,Sirtori P,Chionna R,Barzizza L,Rubinacci A

更新日期：1996-03-01 00:00:00

abstract：:The IGFs are ubiquitous and have pleoitropic effects. They are critical for normal growth and development, and for normal functioning of adult tissues. A liver-specific gene-deletion knockout of the IGF-I gene resulted in a mouse model with reduced circulating IGF-I levels, that led to insulin resistance due to the se...

journal_title：Journal of endocrinological investigation

authors： Yakar S,Pennisi P,Kim CH,Zhao H,Toyoshima Y,Gavrilova O,LeRoith D

更新日期：2005-01-01 00:00:00

abstract：:Recent data seem to suggest that LHRH may be involved in the modulation of PRL secretion. We studied the PRL pattern in 9 males (age range 18-38 yr) with idiopathic hypogonadotropic hypogonadism (IHH) before and during long-term pulsatile LHRH therapy (120-160 ng/kg bw every 120 min sc) in order to evaluate variations...

journal_title：Journal of endocrinological investigation

authors： Giusti M,Traverso L,Cavagnaro P,Torre R,Durante R,Giordano G

更新日期：1989-09-01 00:00:00

abstract：PURPOSE:To report the clinical implications of an initial experience with transoral endoscopic thyroidectomy vestibular approach (TOETVA). METHODS:From March to November 2017, five cases of TOETVA were performed. Data reported include patient demographics, indication for surgery, extent of surgery, operative time, the...

journal_title：Journal of endocrinological investigation

authors： Bakkar S,Al Hyari M,Naghawi M,Corsini C,Miccoli P

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:We designed a single-center retrospective study to assess the QT interval duration and to describe cardio vascular events among patients treated with mitotane for a adrenocortical carcinoma (ACC). DESIGN:We selected 14 patients (6 males and 8 females) that met the following criteria: ACC treated with mitotan...

journal_title：Journal of endocrinological investigation

authors： Ederhy S,Cohen A,Dufaitre G,Chaderevian R,Abbas H,Bertagna X,Libé R

更新日期：2012-11-01 00:00:00

abstract：:E-cadherin and catenins play a major role in neoplastic cell behavior as a suppressor of invasion and/or metastasis. The aim of this study was to determine E-cadherin, alpha-catenin and beta-catenin expressions in papillary thyroid carcinoma (PTC) and to correlate the results of expression to initial clinicopathologic...

journal_title：Journal of endocrinological investigation

authors： Kapran Y,Ozbey N,Molvalilar S,Sencer E,Dizdaroğlu F,Ozarmağan S

更新日期：2002-07-01 00:00:00

abstract：:A case of malignant islet-cell tumor with oncocytic features occurring in a 54-year-old woman with symptoms of organic hypoglycemia is reported. The tumor was composed of ribbons of cells arranged in an endocrine pattern. The cytoplasm of these cells was eosinophilic and finely granular. Ultrastructurally, the cells c...

journal_title：Journal of endocrinological investigation

authors： Sadoul JL,Saint-Paul MC,Hoffman P,Plazza M,Birtwisle Y,Freychet P,Loubiere R

更新日期：1992-03-01 00:00:00

abstract：:Endemic goiter in Morocco is localized in the Rif and Atlas mountains. In this study, performed in the Skoura-Toundoute areas (high Atlas), we demonstrate that iodine deficiency is the main factor involved in the development of endemic goiter. However it may not constitute the only etiological factor. The median urina...

journal_title：Journal of endocrinological investigation

authors： Aquaron R,Zarrouck K,el Jarari M,Ababou R,Talibi A,Ardissone JP

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:In contrast with maximal voluntary resistance exercise, which is allegedly considered a potent GH stimulus in young subjects, evaluation of GH response to whole-body vibrations (WBV) has yielded conflicting results. METHODS:The acute effects of WBV alone (test A), maximal voluntary isometric contractions (M...

journal_title：Journal of endocrinological investigation

authors： Sartorio A,Agosti F,De Col A,Marazzi N,Rastelli F,Chiavaroli S,Lafortuna CL,Cella SG,Rigamonti AE

更新日期：2011-03-01 00:00:00

abstract：:Lipopolysaccharide (LPS)-induced inflammatory stress activates the hypothalamus-pituitary-adrenal (HPA) function. Interleukin-I (IL-1) is one of the key factors during this event; however, the mechanisms mediating IL-1 stimulation of HPA axis are still unclear. The present study evaluated the possible involvement of g...

journal_title：Journal of endocrinological investigation

authors： Guo AL,Petraglia F,Nappi RE,Criscuolo M,Ficarra G,Salvestroni C,Genazzani AD,Trentini GP,Genazzani AR

更新日期：1996-02-01 00:00:00

abstract：:Entering puberty is one of the most important milestones in life. Studies from around the world have shown that age of pubertal changes onset can vary with race and ethnicity, environmental conditions, geographical location and nutrition. In the last century, the onset of puberty progressively shifted back towards you...

journal_title：Journal of endocrinological investigation

authors： Castellino N,Bellone S,Rapa A,Vercellotti A,Binotti M,Petri A,Bona G

更新日期：2005-07-01 00:00:00

abstract：:The AA. studied the glycometabolic activity of prazosin, a hypotensive drug with an adrenergic blocking activity of alpha-1-selective type. Twenty-two moderately hypertensive subjects were studied. Their ages ranged from 37 to 57 years; 10 of the patients had non-insulin dependent diabetes mellitus. After overnight fa...

journal_title：Journal of endocrinological investigation

authors： Ferlito S,Puleo F,Carrà G,Damante G,Di Vincenzo S,Del Campo F

更新日期：1983-06-01 00:00:00

abstract：:A strong relationship was previously described between the nocturnal oscillations of plasma renin activity (PRA) and the sleep cycles, with levels of PRA that increase during non rapid eye movement sleep and decrease during rapid eye movement sleep. This study was designed to determine whether ritanserin, a 5-hydroxyt...

journal_title：Journal of endocrinological investigation

authors： Brandenberger G,Luthringer R,Muller G,Gronfier C,Schaltenbrand N,Macher JP,Muzet A,Follenius M

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVE:Increased inhibin A serum and plasma levels in the second trimester are significantly associated with the development of preeclampsia. The measurement of inhibin A during early pregnancies may be helpful to predict those at risk of this disorder. The purpose of this study was to determine whether the 769G>A v...

journal_title：Journal of endocrinological investigation

authors： Kim SY,Lim JH,Yang JH,Kim MY,Kim MH,Park SY,Ryu HM

更新日期：2008-08-01 00:00:00

abstract：:Liver function is well maintained with increasing age. The aim of our study was to investigate if long-term moderate (

journal_title：Journal of endocrinological investigation

authors： Pinzani P,Petruzzi E,Orlando C,Malentacchi F,Petruzzi I,Pazzagli M,Masotti G

更新日期：2005-01-01 00:00:00

abstract：:Pendred syndrome is an autosomal recessive disorder characterized by congenital sensorineural deafness, goiter, and impaired iodide organification. It is caused by mutations in the PDS gene. Most published mutation studies of Pendred syndrome have dealt with Western populations. In this study, we examined clinical and...

journal_title：Journal of endocrinological investigation

authors： Snabboon T,Plengpanich W,Saengpanich S,Sirisalipoch S,Keelawat S,Sunthornyothin S,Khovidhunkit W,Suwanwalaikorn S,Sridama V,Shotelersuk V

更新日期：2007-12-01 00:00:00