Abstract:
:This study was performed to determine whether phenotypically healthy sisters of women with polycystic ovary syndrome (PCOS) have evidence of insulin resistance. We studied 54 women: 17 with PCOS, 17 sisters of these probands and 20 control women with similar age, body mass index (BMI) and waist-to-hip ratio (WHR). The PCOS sisters had neither clinical nor laboratory evidence of hyperandrogenism. However, estimated insulin resistance indices indicated decreased insulin sensitivity in PCOS sisters compared with the controls. No difference of insulin resistance indices was detected between the PCOS and their sisters. This finding provides additional evidence that there is a hereditary trait regarding insulin resistance in the PCOS families.
journal_name
J Endocrinol Investjournal_title
Journal of endocrinological investigationauthors
Diamanti-Kandarakis E,Alexandraki K,Bergiele A,Kandarakis H,Mastorakos G,Aessopos Adoi
10.1007/BF03347535keywords:
subject
Has Abstractpub_date
2004-11-01 00:00:00pages
931-6issue
10eissn
0391-4097issn
1720-8386pii
5164journal_volume
27pub_type
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journal_title:Journal of endocrinological investigation
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journal_title:Journal of endocrinological investigation
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journal_title:Journal of endocrinological investigation
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journal_title:Journal of endocrinological investigation
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journal_title:Journal of endocrinological investigation
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journal_title:Journal of endocrinological investigation
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journal_title:Journal of endocrinological investigation
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更新日期:1995-04-01 00:00:00
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journal_title:Journal of endocrinological investigation
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journal_title:Journal of endocrinological investigation
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journal_title:Journal of endocrinological investigation
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journal_title:Journal of endocrinological investigation
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