当前位置： SCI文献检索 > JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION期刊下所有文献 > Partial recovery of adrenal function in a patient with autoimmune Addison's disease.

Partial recovery of adrenal function in a patient with autoimmune Addison's disease.

Abstract：

OBJECTIVE:To our knowledge, no case of remission in autoimmune Addison's disease has previously been reported. We describe a patient with primary adrenal insufficiency caused by autoimmune adrenalitis in whom partial remission was observed after 7 yr. CASE:A 39-yr-old male was referred because of extreme fatigue, weight loss, anorexia, nausea, and bouts of fever. During physical examination hyperpigmentation was seen. Laboratory tests showed a plasma cortisol of 0.02 micromol/l (08:30 h). Cortisol failed to increase during the ACTH stimulation test (0.02 to 0.03 micromol/l) and ACTH was markedly elevated (920 pmol/l). Adrenal auto-antibodies were weakly positive. A CT-scan showed no evidence of calcifications or other abnormalities of the adrenal glands. The diagnosis of autoimmune Addison's disease was made and replacement therapy with hydrocortisone and fludrocortisone was started. During the following years the dose of hydrocortisone was gradually decreased. Eventually, the patient decided to stop his medication completely. A repeated ACTH-stimulation test revealed a basal cortisol of 0.25 micromol/l and a peak cortisol of 0.30 micromol/l with a basal ACTH of 178 pmol/l. The patient did not have any complaints. CONCLUSION:Recovery of adrenal insufficiency, due to causes other than autoimmune adrenalitis, has been reported in the past. If our case of partial recovery of autoimmune adrenalitis is not unique this could have profound effects on treatment and follow-up of Addison's disease.

journal_name

J Endocrinol Invest

journal_title

Journal of endocrinological investigation

authors

Smans LC,Zelissen PM

doi

10.1007/BF03345623

subject

Has Abstract

pub_date

2008-07-01 00:00:00

pages

672-4

issue

7

eissn

0391-4097

issn

1720-8386

pii

4751

journal_volume

31

pub_type

杂志文章

相关文献

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION文献大全
  • Chronic stress causes neuroendocrine-immune disturbances without affecting renal vitamin D metabolism in rats.

    abstract：INTRODUCTION:Vitamin D (VD) insufficiency has been repeatedly observed in the medical conditions associated with inflammation, such as cardiovascular disease, diabetes and depression. However, contrasting to the observational evidence, randomized trials of VD supplementation failed to demonstrate such link. Given the r...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-014-0191-5

    authors： Jiang P,Zhang L,Zhu W,Li H,Dang R,Tang M

    更新日期：2014-11-01 00:00:00

  • The effect of hormone replacement therapy in postmenopausal women on urinary C-telopeptide and N-telopeptide of type I collagen, new markers of bone resorption.

    abstract：:To analyze the inhibitory effect of hormone replacement therapy (HRT) on bone resorption, we measured urinary excretion of C-telopeptide (CTX) and N-telopeptide (NTX) of type I collagen as new markers of bone resorption and assessed their correlation with bone mineral density, in comparison with urinary pyridinoline (...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03347294

    authors： Taga M,Uemura T,Minaguchi H

    更新日期：1998-03-01 00:00:00

  • Coexisting hyperparathyroidism with thyrotoxicosis.

    abstract：:The coexistence of hyperparathyroidism complicating thyrotoxicosis is quite rare. We report the case of one patient who presented with thyrotoxicosis, (total thyroxine of 15.1 micrograms/dl (5-13), free thyroxine index of 18 (4-15) and triiodothyronine by RIA of 305 ng/dl (70-230) and asymptomatic hypercalcemia of 15 ...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章,评审

    doi：10.1007/BF03346819

    authors： McGowan DM,Vaswani A,Shperling I

    更新日期：1991-04-01 00:00:00

  • Chronic stress inhibits hypothalamus-pituitary-thyroid axis and brown adipose tissue responses to acute cold exposure in male rats.

    abstract：PURPOSE:Cold exposure activates the hypothalamus-pituitary-thyroid (HPT) axis, response blunted by previous acute stress or corticosterone administration. Chronic stressors can decrease serum T3 concentration, and thyrotropin-releasing hormone (Trh) expression in the paraventricular nucleus (PVN), but impact on the res...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-020-01328-z

    authors： Castillo-Campos A,Gutiérrez-Mata A,Charli JL,Joseph-Bravo P

    更新日期：2020-07-30 00:00:00

  • Serum leptin levels in males with delayed puberty during short-term pulsatile GnRH administration.

    abstract：:Leptin may be a possible trigger for puberty. In normal males, it has been shown that leptin increases from the pre-pubertal to the early pubertal stage, and then declines in the late pubertal stage. We examined leptin levels in six male adolescents (mean age 16.3+/-0.6 yr; range 14.2-17.6 yr) with delayed puberty (co...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03345471

    authors： Giusti M,Guido R,Valenti S,Giordano G

    更新日期：1999-01-01 00:00:00

  • Thyroid nodules in recurrent multinodular goiters are predominantly polyclonal.

    abstract：:Not only thyroid adenomas and carcinomas, but also the majority of single and well delimited goiter nodules, even if morphologically heterogeneous, are of clonal origin. However, it is still unknown whether the nodules of rapidly growing, recurrent goiters are clonal or polyclonal. We investigated by PCR-based analysi...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03350774

    authors： Harrer P,Broecker M,Zint A,Schatz H,Zumtobel V,Derwahl M

    更新日期：1998-06-01 00:00:00

  • Psychobiology of facial attractiveness.

    abstract：:The last decade has witnessed an upsurge of interest in the research on facial attractiveness. The development of computer graphics has allowed to objectively investigate the conserved features of attractive faces. Averageness, symmetry and sex-specific traits have been associated with attractiveness. The effect of av...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章,评审

    doi：

    authors： Cellerino A

    更新日期：2003-01-01 00:00:00

  • The effect of short-term growth hormone or low-dose oxandrolone treatment in boys with constitutional growth delay.

    abstract：:We evaluated the effect of six-month treatment with growth hormone (GH) or low-dose oxandrolone in a group of boys with constitutional growth delay (CGD). Sixteen boys were randomly assigned to two treatment groups. Group 1 received GH (0.6 U/kg/week sc 5-6 times/week) and Group 2 received oxandrolone (0.07 mg/kg po)....

    journal_title：Journal of endocrinological investigation

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/BF03347908

    authors： Loche S,Pintor C,Cambiaso P,Lampis A,Carta D,Corda R,Cappa M

    更新日期：1991-10-01 00:00:00

  • Impact of short-term treatment with benzodiazepines and imidazopyridines on glucose metabolism in healthy subjects.

    abstract：AIM:In the last years there has been a progressive reduction of the average duration of sleep and an increase in the incidence of sleep disturbances. At the same time, an increase of the incidence of the metabolic syndrome has been described, partly attributable to the progressive worsening of dietary habits and the in...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s40618-013-0016-y

    authors： Gramaglia E,Ramella Gigliardi V,Olivetti I,Tomelini M,Belcastro S,Calvi E,Dotta A,Ghigo E,Benso A,Broglio F

    更新日期：2014-02-01 00:00:00

  • Principles and clinical applications of liquid chromatography - tandem mass spectrometry for the determination of adrenal and gonadal steroid hormones.

    abstract：:Liquid-chromatography - tandem mass spectrometry (LC-MS/MS) is becoming the method of choice for clinical steroid analysis. In most instances, it has the advantage of higher sensitivity, better reproducibility and greater specificity than commercial immunoassay techniques. The method requires only minimal sample prepa...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章,评审

    doi：10.3275/7843

    authors： Kulle AE,Welzel M,Holterhus PM,Riepe FG

    更新日期：2011-10-01 00:00:00

  • Diagnosis of normocalcemic hyperparathyroidism by oral calcium loading test.

    abstract：:We evaluated the oral calcium-loading test (OCLT) in diagnosing normocalcemic primary hyperparathyroidism. Calcium and PTH levels were measured before, 60, 120 and 180 min after oral 1 g of calcium gluconolactate administration in 102 consecutive females with high circulating PTH levels, and 25 controls. Patients were...

    journal_title：Journal of endocrinological investigation

    pub_type： 临床试验,杂志文章

    doi：10.1007/BF03345180

    authors： Hagag P,Revet-Zak I,Hod N,Horne T,Rapoport MJ,Weiss M

    更新日期：2003-04-01 00:00:00

  • Percutaneous intranodular ethanol injection: a new treatment for autonomous thyroid adenoma.

    abstract：:Established methods for definitive ablation of autonomous thyroid nodules are surgery and radioiodine. Since it has been demonstrated that percutaneous ethanol injection can inactivate parathyroid adenomas and small hepatocellular carcinomas, we started a trial of this treatment in patients with autonomous thyroid nod...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03348753

    authors： Paracchi A,Ferrari C,Livraghi T,Reschini E,Macchi RM,Bergonzi M,Raineri P

    更新日期：1992-05-01 00:00:00

  • Growth hormone treatment in non-growth hormone-deficient short children.

    abstract：:The unlimited availability of GH obtained by recombinant DNA technology has allowed optimization of treatment in GH-deficient (GHD) children. At the same time it has prompted a number of studies in conditions not characterized by GHD such as Turner syndrome, intrauterine growth retardation, chronic renal failure and o...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章,评审

    doi：10.1007/BF03345367

    authors： Loche S,Casini MR,Ubertini GM,Cappa M

    更新日期：2005-02-01 00:00:00

  • Hypokalemic thyrotoxic periodic paralysis in a Caucasian male with Graves' disease.

    abstract：:The case of a 34-yr-old Caucasian male with Graves' disease presenting with a flaccid quadriplegia and severe hypokalemia is reported. The weakness was prevalent at the lower extremities and began during nocturnal sleep, after a strenuous physical exertion performed during the day. Correction of hypokalemia promptly r...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03347807

    authors： Celani MF,Bonati ME,Cavalli M

    更新日期：1995-03-01 00:00:00

  • Biochemical short-term changes produced by hormonal replacement therapy.

    abstract：:Seventy-one white women within 6 months to 6 years postmenopause were randomly assigned to three treatment groups: (a) placebo, (b) calcium, (c) cyclic estrogen-progestin plus calcium. Calcium was given as calcium carbonate with meals to attain an intake of 1,700 mg daily in the latter two groups. All women received 4...

    journal_title：Journal of endocrinological investigation

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/BF03347118

    authors： Aloia JF,Vaswani A,Yeh JK,McGowan DM,Ross P

    更新日期：1991-12-01 00:00:00

  • Cardiovascular outcome trials and major cardiovascular events: does glucose matter? A systematic review with meta-analysis.

    abstract：PURPOSE:We did a meta-analysis with meta-regression to evaluate the relationship between hemoglobin A1c (A1C) reduction and the primary CV outcome of cardiovascular outcome trials (CVOTs). METHODS:We used a random effects meta-analysis of the 12 CVOTs to quantify the effect of A1C reduction on major cardiovascular eve...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章,meta分析

    doi：10.1007/s40618-019-01047-0

    authors： Giugliano D,Chiodini P,Maiorino MI,Bellastella G,Esposito K

    更新日期：2019-10-01 00:00:00

  • Primary hyperparathyroidism in pregnancy: observations from the Indian PHPT registry.

    abstract：PURPOSE:To present the data on primary hyperparathyroidism (PHPT) in pregnancy from India obtained from a large database maintained over 15 years. METHODS:We retrieved data of all women with gestational PHPT from the Indian PHPT registry between July 2005 and January 2020, and compared their clinical, biochemical, and...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-020-01441-z

    authors： Pal R,Bhadada SK,Gupta N,Behera A,Aggarwal N,Aggarwal A,Raviteja KV,Saikia UN,Kaur G,Arvindbhai SM,Walia R

    更新日期：2020-10-09 00:00:00

  • Apparent mineralocorticoid excess syndromes.

    abstract：:Apparent mineralocorticoid excess (AME) is a syndrome attributable to congenital deficiency of the enzyme 11 beta-dehydrogenase (11 beta-OHSD) which converts active glucocorticoid cortisol to inactive cortisone. When 11 beta-OHSD activity is impaired, cortisol acts as a potent mineralocorticoid and causes hypertension...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章,评审

    doi：10.1007/BF03349763

    authors： Shimojo M,Stewart PM

    更新日期：1995-07-01 00:00:00

  • Pre-operative micronutrient deficiencies in patients with severe obesity candidates for bariatric surgery.

    abstract：PURPOSE:In patients with obesity, micronutrient deficiencies have been reported both before and after bariatric surgery (BS). Obesity is a chronic pro-inflammatory status, and inflammation increases the risk of micronutrient malnutrition. Our objective was to assess in pre-BS patients the prevalence of micronutrient de...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-020-01439-7

    authors： Pellegrini M,Rahimi F,Boschetti S,Devecchi A,De Francesco A,Mancino MV,Toppino M,Morino M,Fanni G,Ponzo V,Marzola E,Abbate Daga G,Broglio F,Ghigo E,Bo S

    更新日期：2020-10-07 00:00:00

  • Effects of metabolic abnormalities, hyperandrogenemia and clomiphene on liver function parameters among Chinese women with polycystic ovary syndrome: results from a randomized controlled trial.

    abstract：PURPOSE:To investigate the effects of metabolic abnormalities, hyperandrogenemia and ovulation induction by clomiphene/acupuncture on liver function parameters among women with polycystic ovary syndrome (PCOS). METHODS:This is a secondary analysis of a randomized controlled trial. All 1000 subjects were diagnosed as P...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-018-0953-6

    authors： Cai WY,Gao JS,Luo X,Ma HL,Ge H,Liu N,Xia Q,Wang Y,Han BW,Wu XK

    更新日期：2019-05-01 00:00:00

  • The role of central serotoninergic and noradrenergic neurons in the regulation of nyctohemeral rhythm of plasma thyrotropin.

    abstract：:A possible participation of central serotoninergic or noradrenergic neurons on nyctohemeral periodicity of plasma TSH concentration was studied in the rat. Control rats exhibited normal nyctohemeral fluctuations of plasma TSH characterized by high AM (09:30) and low PM (18:30) values (397 +/- 45 vs. 207 +/- 28 ng/ml, ...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03348270

    authors： Fukuda H,Mori M,Ohshima K,Kobayashi I

    更新日期：1980-07-01 00:00:00

  • Presence of endothelin-1 in the normal and pathological human thyroid.

    abstract：:An immunohistochemical study with two rabbit polyclonal antibodies I-AR76 and CA-08-351 against Endothelin-1 (ET-1) was performed in 133 human thyroid specimens: 5 normal thyroids, 30 multinodular goiters (15 toxic and 15 nontoxic), 20 Graves' diseases, 5 Hashimoto's thyroiditis, 26 adenomas (6 Hürthle cell, 16 toxic ...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03347834

    authors： Lenziardi M,Viacava P,Fiorini I,Castagna M,Nardini V,Pollina L,De Negri F,Goletti O,Di Coscio G,Bevilacqua G

    更新日期：1995-05-01 00:00:00

  • Cyclical Cushing's disease: report of a case cured by conventional cobaltotherapy.

    abstract：:Preliminary hormonal studies in a 18-y old man with the clinical features of Cushing's syndrome showed inconclusive and conflicting results both in basal conditions and after metyrapone and dexamethasone administration. Therefore the possibility of a cyclical or acyclical fluctuation of adrenal hypersecretion was susp...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03347163

    authors： De Feo ML,Bonfanti L,Romano S,Fusi S,Giusti G,Messeri G,Forti G

    更新日期：1987-02-01 00:00:00

  • Is elevated urotensin II level a predictor for increased cardiovascular risk in subjects with acromegaly?

    abstract：PURPOSE:Acromegaly is a rare disorder existed in the result of overproduction of growth hormone (GH). The disorder is associated with increased cardiovascular risk factors and metabolic abnormalities. Urotensin II (UII), a secreted vasoactive peptide hormone, belonging somatostatin superfamily, plays an essential role ...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-018-0905-1

    authors： Demirpence M,Guler A,Yilmaz H,Sayin A,Pekcevik Y,Turkon H,Colak A,Ari EM,Aslanipour B,Kocabas GU,Calan M

    更新日期：2019-02-01 00:00:00

  • The effects of bed-rest and countermeasure exercise on the endocrine system in male adults: evidence for immobilization-induced reduction in sex hormone-binding globulin levels.

    abstract：BACKGROUND AND AIM:There is limited data on the effects of inactivity (prolonged bed-rest) on parameters of endocrine and metabolic function; we therefore aimed to examine changes in these systems during and after prolonged (56- day) bed-rest in male adults. SUBJECTS AND METHODS:Twenty healthy male subjects underwent ...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章,随机对照试验

    doi：10.3275/7606

    authors： Belavý DL,Seibel MJ,Roth HJ,Armbrecht G,Rittweger J,Felsenberg D

    更新日期：2012-01-01 00:00:00

  • Serum nesfatin-1 and leptin levels in non-obese girls with premature thelarche.

    abstract：AIM:We aimed to investigate serum nesfatin-1 level in girls with premature thelarche (PT) and its relationship with anthropometric parameters and leptin, which are involved in the initiation of pubertal process. SUBJECTS-METHODS:Non-obese girls who presented with the complaint of early (2-8 years) and isolated breast ...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-015-0277-8

    authors： Çatlı G,Anık A,Küme T,Çalan ÖG,Dündar BN,Böber E,Abacı A

    更新日期：2015-08-01 00:00:00

  • Actions of calcium ions and a calcium-influx blocker on basal and TRH- and GnRH-stimulated hormone release in patients with pituitary adenomas.

    abstract：:We investigated the influence of calcium ions on the secretion of anterior pituitary hormones basally and in response to exogenous hypothalamic releasing factors in 6 men with pituitary tumors. To this end, concentrations of LH, FSH, TSH, growth hormone and prolactin were measured in blood collected at 10-min interval...

    journal_title：Journal of endocrinological investigation

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/BF03348164

    authors： Davis M,Nassberg B,Borges JL,Iranmanesh A,Lizzaralde G,Santen RJ,Drake C,Rogol AD,Kaiser DL,Thorner MO

    更新日期：1987-10-01 00:00:00

  • Effects of somatostatin in a case of severe hypoglycemia due to nesidioblastosis.

    abstract：:The Authors have studied the effects of somatostatin (SRIF) treatment in an infant affected by hypoglycemia due to nesidioblastosis. During iv infusion with SRIF we observed a marked increase of blood glucose levels; concomitantly insulin secretion was almost completely suppressed. In contrast, during treatment with p...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03350454

    authors： Roti E,Ghinelli C,Bandini P,Del Rossi C,Emanuele R,Robuschi G,Gnudi A

    更新日期：1981-04-01 00:00:00

  • Subclinical hypothyroidism: the state of the art.

    abstract：:Subclinical hypothyroidism (SH) is a common clinical problem, particularly in adulthood and the elderly. Its prevalence is conditioned by several etiological and risk factors. The highest age- and sex-specific rates are in women over 60. SH may be associated with manifestations of mild thyroid failure, which may rever...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章,评审

    doi：10.1007/BF03345571

    authors： Arrigo T,Wasniewska M,Crisafulli G,Lombardo F,Messina MF,Rulli I,Salzano G,Valenzise M,Zirilli G,De Luca F

    更新日期：2008-01-01 00:00:00

  • Diabetes insipidus with spontaneous remission.

    abstract：:Pathogenesis of idiopathic diabetes insipidus is unknown and the clinical course of the disease is permanent. However, we observed one patient who was diagnosed of idiopathic diabetes insipidus spontaneously reverted after approximately 13 months. The cause and pathogenesis of the disease were not evident. However, so...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03350038

    authors： Ohshima K,Okada S,Onai T,Umahara M,Mori M,Kobayashi I,Kobayashi S,Katakai S

    更新日期：1989-11-01 00:00:00