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Growth hormone treatment in non-growth hormone-deficient short children.

Abstract：

:The unlimited availability of GH obtained by recombinant DNA technology has allowed optimization of treatment in GH-deficient (GHD) children. At the same time it has prompted a number of studies in conditions not characterized by GHD such as Turner syndrome, intrauterine growth retardation, chronic renal failure and other chromosomal and genetic abnormalities associated with short stature. Several controlled and uncontrolled studies have now reported the adult height of patients with short stature and normal GH secretion. Critical reviewing of the data shows that some short non-GHD children may benefit from a prolonged treatment with GH. However, further studies are needed in order to be able to identify the subjects for whom treatment is really beneficial.

journal_name

J Endocrinol Invest

journal_title

Journal of endocrinological investigation

authors

Loche S,Casini MR,Ubertini GM,Cappa M

doi

10.1007/BF03345367

keywords:

subject

Has Abstract

pub_date

2005-02-01 00:00:00

pages

193-8

issue

2

eissn

0391-4097

issn

1720-8386

pii

2958

journal_volume

28

pub_type

杂志文章,评审

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