Healthy centenarian subjects: the effect of red wine consumption on liver function tests.

abstract：:Recently, bromocriptine has been successfully introduced as medical therapy for the pituitary hypersecreting syndromes of hyperprolactinemia and acromegaly. Subsequently, an inhibitory effect on ACTH secretion was reported using bromocriptine in Cushing's disease. While most studies have focused on the acute response ...

journal_title：Journal of endocrinological investigation

authors： Kapcala LP,Jackson IM

更新日期：1982-03-01 00:00:00

abstract：:Patients with simple exogenous obesity are characterized by increased B-endorphin (B-EP) plasma levels, despite normal ACTH and B-Lipotropin (B-LPH). To evaluate the origin of such an hyperendorphinemia, 42 obese patients were submitted to a short overnight dexamethasone suppression test (DST: 1 mg at 23:00 h). Blood ...

journal_title：Journal of endocrinological investigation

authors： Facchinetti F,Giovannini C,Petraglia F,Barletta C,Comitini G,Genazzani AR

更新日期：1988-02-01 00:00:00

abstract：INTRODUCTION:Growth hormone resistance defines several genetic (primary) and acquired (secondary) pathologies that result in completely or partially interrupted activity of growth hormone. An archetypal disease of this group is the Laron-type dwarfism caused by mutations in growth hormone receptors. The diagnosis is ba...

journal_title：Journal of endocrinological investigation

authors： Kurtoğlu S,Hatipoglu N

更新日期：2016-01-01 00:00:00

abstract：:We report the case of a 17-year-old girl presenting short stature (height 149 cm, below the 3rd percentile), obesity (weight 83.5 kg, body mass index 37 kg/m2) and secondary amenorrhea, in whom endocrinological evaluation disclosed an absolute lack of GH responsiveness to both suprapituitary challenges and repetitive ...

journal_title：Journal of endocrinological investigation

authors： Scacchi M,Alé G,Silvestri P,Cavagnini F

更新日期：1995-05-01 00:00:00

abstract：:The aim of this study was to investigate the role of multimodality treatment in patients with anaplastic thyroid carcinoma. From 1992 to 1999, 39 consecutive patients with a histologically or cytologically proven anaplastic thyroid carcinoma were referred to the Thyroid Center of Padua General Hospital. There were 28 ...

journal_title：Journal of endocrinological investigation

authors： Busnardo B,Daniele O,Pelizzo MR,Mazzarotto R,Nacamulli D,Devido D,Mian C,Girelli ME

更新日期：2000-12-01 00:00:00

abstract：INTRODUCTION:Since varicocele is often associated with other venous abnormalities, this study was undertaken to evaluate the frequency of dilation of the periprostatic venous plexus (DPVP) in these patients and the effects of this association on sperm parameters before and after varicocelectomy. MATERIALS AND METHODS:...

journal_title：Journal of endocrinological investigation

authors： Condorelli RA,Calogero AE,Mongioi' L,Vicari E,Russo GI,Lanzafame F,La Vignera S

更新日期：2016-05-01 00:00:00

abstract：:Disulfide bonds are formed between the sulfhydryl groups in two cysteine residues of a protein. The formation of these bonds is necessary for the proper folding of a protein into its active three-dimensional form. In this study, the genes associated with disulfide bond formation of proteins from the rat thyroid cell l...

journal_title：Journal of endocrinological investigation

authors： Park S,Hwang I,Shong M,Kwon OY

更新日期：2003-02-01 00:00:00

abstract：:Juvenile Rheumatoid Arthritis (JRA) is frequently associated with osteoporosis. In order to determine if JRA osteoporosis is related to reduced formation or to increased bone resorption or both, serum levels of calcium (Ca), phosphorus (PO4), magnesium (Mg), alkaline phosphatase (ALP), parathormone (PTHi), 25-hydroxyv...

journal_title：Journal of endocrinological investigation

authors： Falcini F,Ermini M,Bagnoli F

更新日期：1998-01-01 00:00:00

abstract：:Erectile dysfunction (ED) has been defined by the National Institute of Health (NIH) as the inability to achieve and/or to maintain an erection for a sufficiently long period of time so as to permit satisfactory sexual intercourse. ED affects millions of men throughout the world and could have a negative influence on ...

journal_title：Journal of endocrinological investigation

authors： Foresta C,Caretta N,Aversa A,Bettocchi C,Corona G,Mariani S,Rossato M

更新日期：2004-01-01 00:00:00

abstract：:Insulin degradation in IM-9 cultured human lymphocytes occurs extracellularly. In the presence of 0.1% bovine serum albumin, insulin degradation products are formed that are soluble in 5% trichloroacetic acid. In the presence of 5% bovine serum albumin, the major products of insulin degradation are insoluble in 5% tri...

journal_title：Journal of endocrinological investigation

authors： Misbin RI,Mehl TD

更新日期：1980-01-01 00:00:00

abstract：:17alpha-hydroxylase deficiency (17alpha-OHDS) results in decreased production of cortisol and sex steroids and hypokalemia secondary to excess mineralocorticoids. It has long been known that glucocorticoid deficiency is associated with impaired urinary dilution and increased secretion of vasopressin (AVP). On the othe...

journal_title：Journal of endocrinological investigation

authors： Leal AM,Elias PC,Moreira AC

更新日期：2002-07-01 00:00:00

abstract：:Prolactin, growth hormone and thyroid stimulating hormone responses to thyrotropin releasing hormone (TRH) and metoclopramide were determined in 12 alcoholic men with biopsy proven liver disease and were compared to those of 8 age matched normal controls. All subjects were challenged with TRH (400 micrograms) and meto...

journal_title：Journal of endocrinological investigation

authors： Van Thiel DH,Gavaler JS,Sanghvi A

更新日期：1982-09-01 00:00:00

abstract：:Pegvisomant, a GH receptor antagonist, is a new pharmaceutical approach to acromegaly. It enables IGF-I levels to return in the age- and sex-reference range in approximately 90% of patients. This new approach is particularly beneficial in those patients who do not experience control of hormone hypersecretion after sur...

journal_title：Journal of endocrinological investigation

authors： Colao A,Pivonello R,Cappabianca P,Auriemma RS,De Martino MC,Ciccarelli A,de Divitiis E,Lombardi G

更新日期：2003-01-01 00:00:00

abstract：:In 1939 Alan Turing, a major scholar in the field of mechanical computation, described a system whose computational power was beyond that of a discrete, finite state machine (Turing Machine). The composition of this system was likely the first example of what is now called an hybrid computational system. Since then, d...

journal_title：Journal of endocrinological investigation

authors： Sandri G

更新日期：2004-01-01 00:00:00

abstract：:The mechanisms underlying the antifertility effects of hyperprolactinemia have yet to be established in an appropriate experimental model. Hyperprolactinemia is a known side effect of fluphenazine, a broad spectrum, long-acting phenothiazine known to be dopamine type-D2 receptor antagonist. In our earlier study in adu...

journal_title：Journal of endocrinological investigation

authors： Aleem M,Choudhari J,Padwal V,Balasinor N,Parte P,Gill-Sharma MK

更新日期：2005-01-01 00:00:00

abstract：:Few data are available on serum free thyroid hormone concentration in patients with T3-toxicosis. In this study total and free T4 and T3 and TBG were evaluated in 35 subjects with T3-toxicosis, including 12 with untreated Graves' disease, 5 Graves' patients on methimazole treatment, 13 with autonomous adenoma, 3 with ...

journal_title：Journal of endocrinological investigation

authors： Ferrari C,Romussi M,Rampini P,Benco R,Boghen M,Paracchi A,Frezzati S

更新日期：1983-02-01 00:00:00

abstract：:Forty-eight morbidly obese patients were placed on a very low calorie (800 kcal) formula diet (OPTIFAST) for a 10-week period with the goal of achieving 10% weight loss within this time. Weekly serum leptin measurements were performed to determine whether changes in this adipose protein would serve as a useful marker ...

journal_title：Journal of endocrinological investigation

authors： Xenachis C,Samojlik E,Raghuwanshi MP,Kirschner MA

更新日期：2001-12-01 00:00:00

abstract：:Pituitary metastases account for about 1% of operated pituitary lesions. Most derive from primaries in the breast or lung. Pituitary metastases from hepatocellular carcinoma (HCC) have rarely been reported. We describe a patient in whom headache and left external ophthalmoplegia were the only presenting signs of a cli...

journal_title：Journal of endocrinological investigation

authors： Hirsch D,Benbassat CA,Drozd T,Okon E,Blum I

更新日期：2005-05-01 00:00:00

abstract：:A 41-year-old male with primary hypothyroidism and a huge TSH-secreting pituitary tumor presented with a bleeding nasal mass that was initially misdiagnosed as a paraganglioma. Other unique features of the case include lack of complaints related to hypothyroidism, an extremely elevated TSH level of 3474 mU/l, and a lo...

journal_title：Journal of endocrinological investigation

authors： Ghannam NN,Hammami MM,Muttair Z,Bakheet SM

更新日期：1999-06-01 00:00:00

abstract：:Peroxisome proliferator activated receptor (PPAR)gamma plays a pivotal role in regulating adipocyte differentiation and metabolism, but also has an antiproliferative effect in several tissues, including colonic mucosa, where it is highly expressed. Loss-of-function mutations have been reported in about 10% of sporadic...

journal_title：Journal of endocrinological investigation

authors： Bogazzi F,Ultimieri F,Raggi F,Russo D,Brogioni S,Cosci C,Gasperi M,Costa A,Viacava P,Mosca F,Bartalena L,Martino E

更新日期：2003-11-01 00:00:00

abstract：:During diabetic ketoacidosis, in 17 adult patients, significant decreases in serum TBG and total T4 levels were observed, without significant alteration of the T4 to TBG binding property. In addition, serum free T4 (FT4) was moderately elevated and the TSH response to TRH was markedly blunted. No correlation, however,...

journal_title：Journal of endocrinological investigation

authors： Glinoer D,Naeije R,Golstein J,Fernandez-Deville M,Vanhaelst L

更新日期：1980-01-01 00:00:00

abstract：AIM:This 3-month study compared the effect on overall glycemic control of adding biphasic insulin aspart 30 (BIAsp30) and premixed human insulin 30/70 (BHI30) to metformin (met) in insulin-naïve, obese patients (30 males/20 females) with Type 2 diabetes (T2DM). MATERIAL/SUBJECTS: At baseline, patients had a mean age of...

journal_title：Journal of endocrinological investigation

authors： Velojic-Golubovic M,Mikic D,Pesic M,Dimic D,Radenkovic S,Antic S

更新日期：2009-01-01 00:00:00

abstract：:In mature female rats the administration of testosterone led to a striking reduction of hepatic alcohol dehydrogenase activity, whereas the hepatic microsomal ethanol oxidizing system as well as catalase were both increased in activity under these experimental conditions. Conversely, estradiol left the activities of a...

journal_title：Journal of endocrinological investigation

authors： Teschke R,Wiese B

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND:Glucagon-like peptide-1 (GLP-1) and its potent analog, exendin-4, are well known to inhibit β- cell apoptosis and promote β-cell proliferation. Meanwhile, cytokines, such as interleukin-1β (IL-1β), stimulate inducible nitric oxide synthase (iNOS) expression and nitric oxide overproduction leading to β-cell d...

journal_title：Journal of endocrinological investigation

authors： Liu XH,Wang YP,Wang LX,Chen Z,Liu XY,Liu LB

更新日期：2013-11-01 00:00:00

abstract：:A strong relationship was previously described between the nocturnal oscillations of plasma renin activity (PRA) and the sleep cycles, with levels of PRA that increase during non rapid eye movement sleep and decrease during rapid eye movement sleep. This study was designed to determine whether ritanserin, a 5-hydroxyt...

journal_title：Journal of endocrinological investigation

authors： Brandenberger G,Luthringer R,Muller G,Gronfier C,Schaltenbrand N,Macher JP,Muzet A,Follenius M

更新日期：1996-09-01 00:00:00

abstract：:The effects of short term administration of 200 MRC U of synthetic salmon calcitonin (sCT) daily on carbohydrate metabolism were investigated in 10 patients with various bone diseases, 3 of whom had type II diabetes mellitus and 3 of whom had impaired glucose tolerance. Blood glucose levels during the nocturnal postab...

journal_title：Journal of endocrinological investigation

authors： Giustina G,Cerudelli B,Cimino A,Rigosa C,Rotondi A,Radaeli E

更新日期：1985-02-01 00:00:00

abstract：:E-cadherin and catenins play a major role in neoplastic cell behavior as a suppressor of invasion and/or metastasis. The aim of this study was to determine E-cadherin, alpha-catenin and beta-catenin expressions in papillary thyroid carcinoma (PTC) and to correlate the results of expression to initial clinicopathologic...

journal_title：Journal of endocrinological investigation

authors： Kapran Y,Ozbey N,Molvalilar S,Sencer E,Dizdaroğlu F,Ozarmağan S

更新日期：2002-07-01 00:00:00

abstract：:The pituitary and peripheral responses to L-T4 and L-T3 therapy were studied in 12 patients with congenital goitrous hypothyroidism, in 10 patients with an ectopic thyroid and onset of hypothyroidism at 3-8 years of age, and in 6 patients with adult-onset hypothyroidism, after they had had their chronic thyroid hormon...

journal_title：Journal of endocrinological investigation

authors： Cavaliere H,Medeiros-Neto GA,Rosner W,Kourides IA

更新日期：1985-12-01 00:00:00

abstract：INTRODUCTION:Phosphodiesterase 5 inhibitors (PDE5i) were developed while investigating novel treatments for coronary artery disease, but their andrological side effects shifted their indication toward the management of erectile dysfunction. Although PDE5i are now also indicated for pulmonary arterial hypertension and t...

journal_title：Journal of endocrinological investigation

authors： Pofi R,Gianfrilli D,Badagliacca R,Di Dato C,Venneri MA,Giannetta E

更新日期：2016-02-01 00:00:00

abstract：:Osteoporosis is a multifactorial chronic disease that may become even more prevalent and more of a public health problem in the decades to come. Recent research has indicated that a number of macro- and micronutrients are involved in the development of bone health. In the past decade it became evident that vitamin K p...

journal_title：Journal of endocrinological investigation

authors： Francucci CM,Rilli S,Fiscaletti P,Boscaro M

更新日期：2007-01-01 00:00:00