The 769G>A variant of the inhibin-alpha gene in Korean patients with preeclampsia.

Abstract:

OBJECTIVE:Increased inhibin A serum and plasma levels in the second trimester are significantly associated with the development of preeclampsia. The measurement of inhibin A during early pregnancies may be helpful to predict those at risk of this disorder. The purpose of this study was to determine whether the 769G>A variant of the inhibin alpha (INHalpha) gene was associated with preeclampsia. PATIENTS AND METHODS:We screened the 769G>A variation in 162 preeclamptic patients and in 202 normal pregnancies. The 769G>A variant of the INHalpha gene was determined by the PCR-based restriction fragment length polymorphism analysis and DNA sequencing. RESULTS:We found no variation between the normal subjects and the preeclamptic patients. CONCLUSION:The 769G>A variant of the INHalpha gene may be rare in Korean patients with preeclampsia.

journal_name

J Endocrinol Invest

authors

Kim SY,Lim JH,Yang JH,Kim MY,Kim MH,Park SY,Ryu HM

doi

10.1007/BF03346418

subject

Has Abstract

pub_date

2008-08-01 00:00:00

pages

700-3

issue

8

eissn

0391-4097

issn

1720-8386

pii

4897

journal_volume

31

pub_type

杂志文章
  • Seasonal variations in vitamin D in relation to growth in short prepubertal children before and during first year growth hormone treatment.

    abstract:PURPOSE:This study investigated the relationship between seasonal variations in 25-hydroxyvitamin D (25(OH)D) levels and growth in prepubertal children during both the pretreatment year and the first year of GH treatment. METHODS:The study included 249 short prepubertal children with a broad range of GH secretion, GH(...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-015-0360-1

    authors: Andersson B,Swolin-Eide D,Kriström B,Gelander L,Magnusson P,Albertsson-Wikland K

    更新日期:2015-12-01 00:00:00

  • The effect of hormone replacement therapy in postmenopausal women on urinary C-telopeptide and N-telopeptide of type I collagen, new markers of bone resorption.

    abstract::To analyze the inhibitory effect of hormone replacement therapy (HRT) on bone resorption, we measured urinary excretion of C-telopeptide (CTX) and N-telopeptide (NTX) of type I collagen as new markers of bone resorption and assessed their correlation with bone mineral density, in comparison with urinary pyridinoline (...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347294

    authors: Taga M,Uemura T,Minaguchi H

    更新日期:1998-03-01 00:00:00

  • Cognitive functions and mood during chronic thyrotropin-suppressive therapy with L-thyroxine in patients with differentiated thyroid carcinoma.

    abstract:BACKGROUND:Subclinical thyroid dysfunctions may cause cognitive deficits and mood disorders. Chronic TSH-suppressive therapy with L-T(4) causing subclinical hyperthyroidism has been widely used in treatment of patients with thyroid differentiated carcinoma. The impact of this therapy on cognitive functions and mood hav...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.3275/8013

    authors: Jaracz J,Kucharska A,Rajewska-Rager A,Lacka K

    更新日期:2012-09-01 00:00:00

  • Thyroid blood flow rate in man. Electromagnetic flowmetry during operation in euthyroid normal gland, nontoxic goiter, and hyperthyroidism.

    abstract::Human thyroid blood flow rate (TBF) was measured during operations by electromagnetic flowmetry in 75 euthyroid patients with normal thyroid tissue, nodular goiter, or solitary adenoma, and in 22 hyperthyroid patients with diffuse or nodular goiter. Blood flow rate was measured in one to four of the thyroid arteries. ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03349454

    authors: Tegler L,Gillquist J,Anderberg B,Lundström B,Johansson H

    更新日期:1981-07-01 00:00:00

  • Endemic goiter in Morocco (Skoura-Toundoute areas in the high atlas).

    abstract::Endemic goiter in Morocco is localized in the Rif and Atlas mountains. In this study, performed in the Skoura-Toundoute areas (high Atlas), we demonstrate that iodine deficiency is the main factor involved in the development of endemic goiter. However it may not constitute the only etiological factor. The median urina...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03345821

    authors: Aquaron R,Zarrouck K,el Jarari M,Ababou R,Talibi A,Ardissone JP

    更新日期:1993-01-01 00:00:00

  • The phosphodiesterase 5 inhibitor sildenafil decreases the proinflammatory chemokine IL-8 in diabetic cardiomyopathy: in vivo and in vitro evidence.

    abstract:PURPOSE:Interleukin (IL)-8 is a proinflammatory C-X-C chemokine involved in inflammation underling cardiac diseases, primary or in comorbid condition, such diabetic cardiomyopathy (DCM). The phosphodiesterase type 5 inhibitor sildenafil can ameliorate cardiac conditions by counteracting inflammation. The study aim is t...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s40618-018-0977-y

    authors: Giannattasio S,Corinaldesi C,Colletti M,Di Luigi L,Antinozzi C,Filardi T,Scolletta S,Basili S,Lenzi A,Morano S,Crescioli C

    更新日期:2019-06-01 00:00:00

  • Presence of cortistatin in the human pancreas.

    abstract::Cortistatin (CST), a 17-amino acid peptide partially homologous to somatostatin (SRIF), has been originally isolated from the cerebral cortex and recently found in monocytes and macrophages of the immune system. CST binds all 5 SRIF receptors, as well the GH secretagogue (GHS)/ghrelin receptors. CST exerts sleep promo...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347348

    authors: Papotti M,Tarabra E,Allia E,Bozzalla-Cassione F,Broglio F,Deghenghi R,Ghigo E,Muccioli G

    更新日期:2003-08-01 00:00:00

  • Hyperprolactinemia affects spermiogenesis in adult male rats.

    abstract::The mechanisms underlying the antifertility effects of hyperprolactinemia have yet to be established in an appropriate experimental model. Hyperprolactinemia is a known side effect of fluphenazine, a broad spectrum, long-acting phenothiazine known to be dopamine type-D2 receptor antagonist. In our earlier study in adu...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03345528

    authors: Aleem M,Choudhari J,Padwal V,Balasinor N,Parte P,Gill-Sharma MK

    更新日期:2005-01-01 00:00:00

  • Identification of genes in thyrocytes regulated by unfolded protein response by using disulfide bond reducing agent of dithiothreitol.

    abstract::Disulfide bonds are formed between the sulfhydryl groups in two cysteine residues of a protein. The formation of these bonds is necessary for the proper folding of a protein into its active three-dimensional form. In this study, the genes associated with disulfide bond formation of proteins from the rat thyroid cell l...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03345141

    authors: Park S,Hwang I,Shong M,Kwon OY

    更新日期:2003-02-01 00:00:00

  • The role of placental iodine storage in the neonatal thyroid stimulating hormone surge: iodine as a driving force to adapt the terrestrial life.

    abstract:PURPOSE:Iodine plays a pivotal role in adaptation during the transition from intrauterine to extrauterine life. Although it is well known that the placenta plays a role in iodine storage, a relationship between the neonatal thyroid stimulating hormone (TSH) peak and placental iodine concentration has not been establish...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-020-01399-y

    authors: Karaoglan M,İşbilen E

    更新日期:2020-08-28 00:00:00

  • Neuroendocrine-thymus interactions. I. In vitro modulation of thymic factor secretion by thyroid hormones.

    abstract::Several in vivo experimental and clinical studies suggest that the production of thymic hormones, such as thymulin (Zn-FTS), is modulated by thyroid hormones. It was not determined in these studies, however whether such modulation is exerted directly on the thymic epithelial cells which synthesize and secrete thymic h...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03349524

    authors: Mocchegiani E,Amadio L,Fabris N

    更新日期:1990-02-01 00:00:00

  • An exception to the rule: ectopic ACTH production from functional neuroendocrine tissue in an ovarian dermoid cyst.

    abstract::Ectopic ACTH production accounts for 15% of Cushing's syndrome presentations and is characterized by the presence of an excess of ACTH precursors. However in the case presented here ectopic ACTH production was from functional pituitary tissue within an ovarian dermoid cyst. Endocrine investigations showed that the pro...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03343930

    authors: Watson J,Taylor M,Pampiglione J,Rasbridge S,Armitage M

    更新日期:2001-11-01 00:00:00

  • A preliminary study: proteomic analysis of exosomes derived from thyroid-stimulating hormone-stimulated HepG2 cells.

    abstract:BACKGROUND:Thyroid-stimulating hormone (TSH) plays an important role in the regulation of lipid metabolism. However, little is known about the role that exosomes play in the process of TSH-induced lipotoxicity in non-alcoholic fatty liver disease (NAFLD). As a preliminary step, the present study set out to investigate ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-020-01210-y

    authors: Ma S,Shao S,Yang C,Yao Z,Gao L,Chen W

    更新日期:2020-09-01 00:00:00

  • Metastatic renal cell carcinoma to the pituitary gland presenting with hypopituitarism.

    abstract::A 57-year-old man with pituitary metastasis from renal cell carcinoma is reported. He underwent right nephrectomy and total pancreatectomy for renal cell carcinoma and its pancreatic metastasis, respectively. Imaging studies showed an intrasellar mass lesion. The examination revealed panhypopituitarism, diabetes insip...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/BF03345815

    authors: Koshiyama H,Ohgaki K,Hida S,Takasu K,Yumitori K,Shimatsu A,Koh T

    更新日期:1992-10-01 00:00:00

  • Somatostatin-related therapeutics in ophthalmology: a review.

    abstract::Somatostatin and its derivatives have been predominantly studied and succesfully used in endocrinological diseases. This article reviews the rationale of the use of somatostatin and its derivatives in ophthalmology based on current understanding of its action in the eye and summarizes previously published controlled s...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:

    authors: Missotten T,Baarsma GS,Kuijpers RW,van den Born LI,van der Loos T,Croxen R,Hofland LJ,van Hagen PM

    更新日期:2005-01-01 00:00:00

  • Cardiovascular aspects of primary hyperparathyroidism.

    abstract::Data concerning the cardiovascular manifestations of primary hyperparathyroidism (PHPT) are inconsistent, which is due, in part, to the decrease in disease severity over the last several decades. In areas where patients tend to be more symptomatic, data support the presence of cardiovascular findings including myocard...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/BF03346443

    authors: Walker MD,Silverberg SJ

    更新日期:2008-10-01 00:00:00

  • An uncommon large deletion in the androgen-receptor gene in a XY female with complete androgen insensitivity syndrome.

    abstract::Androgen insensitivity is a disorder characterized by an abnormal male sexual development, in which the androgen action is impaired due to structural defects in the androgen receptor gene. We report a case of a 46,XY subject with female phenotype (normal breast and external genitalia) lacking sexual hair, affected wit...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03344130

    authors: Moretti C,Odorisio T,Geremia R,Grimaldi P

    更新日期:2006-05-01 00:00:00

  • Estriol affects prolactin and LH secretion in rats.

    abstract::The effects of estriol on serum prolactin (PRL) and LH levels, on the pituitary response to TRH and LHRH and on the synthesis and release of PRL from the anterior pituitary gland were investigated in female rats. The increase of serum PRL levels after estradiol administration was found to be associated with an increas...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03349902

    authors: Diaz MC,Seilicovich A,Duvilanski BH,Siseles N,Lasaga M,Debeljuk L

    更新日期:1989-01-01 00:00:00

  • Intake of seaweed as part of a single sushi meal, iodine excretion and thyroid function in euthyroid subjects: a randomized dinner study.

    abstract:OBJECTIVE:Globalisation has extended to the kitchen and the Asian cuisine has gained international popularity with sushi and seaweed now being widespread. We explored the possible acute adverse effects of an iodine load from a single sushi-and-seaweed meal as seaweed iodine may induce thyroid dysfunction. METHODS:Nine...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s40618-019-01122-6

    authors: Noahsen P,Kleist I,Larsen HM,Andersen S

    更新日期:2020-04-01 00:00:00

  • Prospective, systematically recorded mycophenolate safety data in Graves' orbitopathy.

    abstract:CONTEXT:The antiproliferative mechanism of mycophenolate acid (MPA) suggests a beneficial effect in patients with Graves' orbitopathy (GO). OBJECTIVE:To systematically analyze for the first time adverse events (AEs) during MPA treatment in GO. DESIGN:Prospective longitudinal study. SETTING:Academic tertiary referral...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/s40618-016-0441-9

    authors: Riedl M,Kuhn A,Krämer I,Kolbe E,Kahaly GJ

    更新日期:2016-06-01 00:00:00

  • Markers of activation of coagulation and fibrinolysis in patients with Cushing's syndrome.

    abstract::Patients with active Cushing's syndrome have an increased thrombotic tendency. We chose to reassess the mechanism underlying the thrombophilic state associated with this clinical condition using sensitive markers of coagulation and fibrinolysis activation in 17 patients with active disease. The results were compared w...

    journal_title:Journal of endocrinological investigation

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF03343697

    authors: Fatti LM,Bottasso B,Invitti C,Coppola R,Cavagnini F,Mannucci PM

    更新日期:2000-03-01 00:00:00

  • A study on the hyperinsulinism of late pregnancy.

    abstract::Much research has demonstrated that in late pregnancy glucose administration causes a marked increase of peripheral insulin levels. To ascertain whether this particular increase is due to increased insulin secretion and/or to reduced hepatic insulin removal, we measured blood glucose, plasma C-peptide and plasma insul...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347933

    authors: Piva I,Erle G,Thiella M,Lora L,Strazzabosco M,Sicolo N,Federspil G

    更新日期:1991-11-01 00:00:00

  • Intracranial volume receptors: possible role on ADH homeostatic control.

    abstract::Volume receptors are situated in many organs and are capable of modulating ADH secretion. We have evaluated the variation of plasma ADH concentration after an experimentally induced increase of cerebrospinal fluid (CSF) pressure (PCSF). The experiment was performed in controlled environmental conditions to avoid pain ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03349891

    authors: Satta A,Palomba D,Demontis MP,Varoni MV,Faedda R,Ginanni A,Anania V

    更新日期:1996-07-01 00:00:00

  • Impact of overweight and obesity on obstetric outcomes.

    abstract::Abnormal nutritional status is an increasingly common complication in developed countries and, as reproductive age women are a part of this trend, the effect of maternal obesity on the pregnancy and neonate must be investigated. Pregestational obesity or overweight condition or an excessive gestational weight gain can...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:10.1007/s40618-014-0058-9

    authors: Triunfo S,Lanzone A

    更新日期:2014-04-01 00:00:00

  • Perindopril attenuates renal tubulointerstitium injury by inhibiting scavenger receptor A over-expression in diabetic rats.

    abstract::Scavenger receptor A (SR-A) is the main receptor through which oxidized LDL (oxLDL) and advanced glycation end products get into the cells. The aim of the present study was to investigate the effect of an ACE inhibitor, perindopril, on the expression of SR-A in renal tubulointerstitium of diabetic rats. Diabetes was i...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.3275/7867

    authors: Sun L,Wen JH,Sun HL,Shu XC,Hu F,Yin DC,Yang Q,Zeng YJ,Sun Y,Liu L

    更新日期:2012-05-01 00:00:00

  • Positive association of serum interleukin-1beta and CRH levels in women with pre-term labor.

    abstract:OBJECTIVE:The aim of this study was to investigate the hypothesis that interleukin-1beta (IL-1beta) might be involved in the increase of the circulating levels of placental-derived CRH leading to the initiation of pre-term labor. SUBJECTS AND METHODS:Forty-eight primigravidae with a singleton viable pregnancy between ...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03347393

    authors: Vitoratos N,Mastorakos G,Kountouris A,Papadias K,Creatsas G

    更新日期:2007-01-01 00:00:00

  • Effects of hypothyroidism and endocrine disruptor-dependent non-thyroidal illness syndrome on the GnRH-gonadotroph axis of the adult male rat.

    abstract::Effects of primary hypothyroidism (HYPO) on the male gonadal axis are controversial, with only scanty data on the gonadotroph cell response and no information on GnRH tuberoinfundibular neurons, even in animal models. HYPO has been reported to variably induce hypogonadotropic hypogonadism, a hypergonadotropic state, o...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章,评审

    doi:

    authors: Toni R,Della Casa C,Castorina S,Cocchi D,Celotti F

    更新日期:2005-01-01 00:00:00

  • Adipokine expression in brown and white adipocytes in response to hypoxia.

    abstract:BACKGROUND:Adipose tissue has emerged as an important endocrine regulator by secreting hormones referred to as adipokines. Recent studies showed that adipose tissue considerably responds to hypoxia. Although the impact of white adipose tissue on regulative processes is established, the importance of brown adipose tissu...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.3275/7964

    authors: Wree A,Mayer A,Westphal S,Beilfuss A,Canbay A,Schick RR,Gerken G,Vaupel P

    更新日期:2012-05-01 00:00:00

  • Growth of a microprolactinoma to a macroprolactinoma during estrogen therapy.

    abstract::Following presentation and diagnosis, microprolactinomas usually follow a benign course and rarely progress to macroprolactinomas. However, clinically significant enlargement of prolactinomas during pregnancy, presumably related to estrogen stimulation, has been reported. This report describes a patient with amenorrhe...

    journal_title:Journal of endocrinological investigation

    pub_type: 杂志文章

    doi:10.1007/BF03349744

    authors: Garcia MM,Kapcala LP

    更新日期:1995-06-01 00:00:00

  • Lack of ACTH lowering effect of sodium valproate in patients with ACTH hypersecretion.

    abstract::The effect of an oral dose of 200 or 400 mg sodium valproate (DPA) on ACTH and cortisol secretion was assessed in 11 patients with Cushing's disease (3 bilaterally adrenalectomized), 3 patients with Nelson's syndrome and 6 patients with Addison's disease. In none of the patients examined DPA induced changes in ACTH (a...

    journal_title:Journal of endocrinological investigation

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF03348396

    authors: Loli P,Berselli ME,Frascatani F,Muratori F,Tagliaferri M

    更新日期:1984-04-01 00:00:00