The role of TLR2 in the host response to pneumococcal pneumonia in absence of the spleen.

abstract：BACKGROUND:China faces a serious HIV epidemic among men who have sex with men (MSM), and a large proportion of new infections are attributed to their regular male sex partners (RP). The objective of this study was to investigate the association between intimate relationship characteristics and HIV-related behaviors amo...

journal_title：BMC infectious diseases

authors： He J,Xu HF,Cheng WB,Zhang SJ,Gu J,Hao YT,Hao C

更新日期：2018-04-02 00:00:00

abstract：BACKGROUND:Legionnaire's disease is one of the major causes of community-acquired pneumonia and is occasionally complicated by neurological symptoms. However, reports of ocular lesions due to Legionnaire's disease are limited. CASE PRESENTATION:We report the case of a patient with Legionnaire's disease presenting as b...

journal_title：BMC infectious diseases

authors： Yamada S,Kitajima T,Marumo S,Fukui M

更新日期：2021-01-07 00:00:00

abstract：BACKGROUND:Injecting drug use is a key risk factor, for several infections of public health importance, especially hepatitis B (HBV) and hepatitis C (HCV). In England and Wales, where less than 1% of the population are likely to be injecting drug users (IDUs), approximately 38% of laboratory reports of HBV, and 95% of ...

journal_title：BMC infectious diseases

authors： Sutton AJ,Gay NJ,Edmunds WJ,Hope VD,Gill ON,Hickman M

更新日期：2006-06-08 00:00:00

abstract：BACKGROUND:Pandemic influenza vaccine manufacturing capacity and distribution agility is enhanced through the availability of equivalent antigen-sparing vaccines. We evaluated equivalence in terms of immunogenicity between GlaxoSmithKline Vaccines' A/California/7/2009 (H1N1)v-like-AS03 vaccines manufactured in Dresden ...

journal_title：BMC infectious diseases

authors： Launay O,Duval X,Fitoussi S,Jilg W,Kerdpanich A,Montellano M,Schwarz TF,Watanveerade V,Wenzel JJ,Zalcman G,Bambure V,Li P,Caplanusi A,Madan A,Gillard P,Vaughn DW

更新日期：2013-09-16 00:00:00

abstract：BACKGROUND:Enterovirus 71 (EV-A71) shows a potential of rapid death, but the natural history of the infection is poorly known. This study aimed to examine the natural history of EV-A71 infection. METHODS:This was a prospective longitudinal observational study performed between January 1st and October 31st, 2012, at th...

journal_title：BMC infectious diseases

authors： Yang SD,Li PQ,Li YM,Li W,Lai WY,Zhu CP,Tao JP,Deng L,Liu HS,Ma WC,Lu JM,Hong Y,Liang YT,Shen J,Hu DD,Gao YY,Zhou Y,Situ MX,Chen YL

更新日期：2017-02-17 00:00:00

abstract：BACKGROUND:A cost effective and efficient diagnostic tool for COVID-19 as near to the point of care (PoC) as possible would be a game changer in the current pandemic. We tested reverse transcription loop mediated isothermal amplification (RT-LAMP), a method which can produce results in under 30 min, alongside standard ...

journal_title：BMC infectious diseases

authors： Österdahl MF,Lee KA,Lochlainn MN,Wilson S,Douthwaite S,Horsfall R,Sheedy A,Goldenberg SD,Stanley CJ,Spector TD,Steves CJ

更新日期：2020-10-20 00:00:00

abstract：BACKGROUND:Cytopenias are the most common HIV-associated hematological abnormality. Cytopenias have been associated with several factors including sex, race/ethnicity, geographical location and comorbidities such as tuberculosis, hepatitis B infection, fever and oral candidiasis. Cytopenias become more prevalent as HIV...

journal_title：BMC infectious diseases

authors： Kyeyune R,Saathoff E,Ezeamama AE,Löscher T,Fawzi W,Guwatudde D

更新日期：2014-09-10 00:00:00

abstract：BACKGROUND:Members of Shewanella species are opportunistic pathogens that are found in marine environments. Currently more than sixty species have been identified, whereas the most commonly clinical cases associated with Shewanella species have involved only two species, i.e., S. algae and S. putrefaciens. We present t...

journal_title：BMC infectious diseases

authors： Zhang F,Fang Y,Pang F,Liang S,Lu X,Kan B,Xu J,Zhao J,Du Y,Wang D

更新日期：2018-09-05 00:00:00

abstract：BACKGROUND:The association of Chlamydia pneumoniae with atherosclerosis is controversial. We investigated the presence of C. pneumoniae and other Chlamydia spp. in atheromatous carotid artery tissue. METHODS:Forty elective carotid endarterectomy patients were recruited (27 males, mean age 65 and 13 females mean age 68...

journal_title：BMC infectious diseases

authors： Ong GM,Coyle PV,Barros D'Sa AA,McCluggage WG,Duprex WP,O'Neill HJ,Wyatt DE,Bamford KB,O'Loughlin B,McCaughey C

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Nonencapsulated and nontypeable Haemophilus influenzae (NTHi) is a major cause of human respiratory tract infections. Some strains of NTHi can cause invasive diseases such as septicemia and meningitis, even if H. influenzae is not generally considered to be an intracellular pathogen. There have been very few...

journal_title：BMC infectious diseases

authors： Sekiya Y,Eguchi M,Nakamura M,Ubukata K,Omura S,Matsui H

更新日期：2008-02-07 00:00:00

abstract：BACKGROUND:Achromobacter xylosoxidans (AX) is known for intrinsic resistance to disinfectants. Our laboratory routine surveillance system detected an unexpected rise in AX bloodstream infections in a 2200-bed hospital. An epidemiological investigation was conducted to find the source and disrupt further transmission. ...

journal_title：BMC infectious diseases

authors： Günther F,Merle U,Frank U,Gaida MM,Mutters NT

更新日期：2016-10-19 00:00:00

abstract：BACKGROUND:Mycobacterium abscessus is a rapidly growing mycobacteria involved in severe infections of the lung, skin, or soft tissue. Macrolides such as clarithromycin are the recommended first line drugs for treatment of M. abscessus infections. However, M. abscessus has dual mechanisms of resistance to macrolides, ma...

journal_title：BMC infectious diseases

authors： Sharma MK,La Y,Janella D,Soualhine H

更新日期：2020-12-10 00:00:00

abstract：BACKGROUND:Staphylococcus aureus is associated with human skin and soft tissue infections (SSTIs); however, the involvement of virulence factors in different clinical presentations is unclear. METHODS:We analyzed methicillin-resistant S. aureus (MRSA) and methicillin-sensitive S. aureus (MSSA) strains from Taiwan to d...

journal_title：BMC infectious diseases

authors： Changchien CH,Chen SW,Chen YY,Chu C

更新日期：2016-06-10 00:00:00

abstract：BACKGROUND:How HIV-1 enter into the eyes remains obscure. We postulated that HIV-1 Tat protein can alter the expression of specific tight-junction proteins and disturb the blood retinal barrier, and contributes to HIV trafficking into the eyes. This study is to determine the effects of HIV-1 Tat proteins on the barrier...

journal_title：BMC infectious diseases

authors： Bai L,Zhang Z,Zhang H,Li X,Yu Q,Lin H,Yang W

更新日期：2008-06-06 00:00:00

abstract：BACKGROUND:The existence of a bi-directional relationship between tuberculosis (TB) and insulin resistance (IR)/diabetes has been alluded to in literature. Although diabetes has been linked to increased tuberculosis risk, the relationship between tuberculosis as a causative factor for IR remains unclear. The study aime...

journal_title：BMC infectious diseases

authors： Philips L,Visser J,Nel D,Blaauw R

更新日期：2017-08-15 00:00:00

abstract：BACKGROUND:Viral load (VL) testing is being scaled up in resource-limited settings. However, not all commercially available VL testing methods have been evaluated under field conditions. This study is one of a few to evaluate the Biocentric platform for VL quantification in routine practice in Sub-Saharan Africa. METH...

journal_title：BMC infectious diseases

authors： Kerschberger B,Mpala Q,Uribe PAD,Maphalala G,de la Tour R,Kalombola S,Bekele A,Chawinga T,Mliba M,Ntshalintshali N,Phugwayo N,Kabore SM,Goiri J,Dlamini S,Ciglenecki I,Fajardo E

更新日期：2018-11-14 00:00:00

abstract：BACKGROUND:Bacterial vaginosis (BV) is a common condition, although its aetiology remains unexplained. The aim of this study was to analyse the composition of vaginal microbiota in women from Greenland to provide a quantitative description and improve the understanding of BV. METHODS:Self-collected vaginal smears and ...

journal_title：BMC infectious diseases

authors： Datcu R,Gesink D,Mulvad G,Montgomery-Andersen R,Rink E,Koch A,Ahrens P,Jensen JS

更新日期：2013-10-16 00:00:00

abstract：BACKGROUND:This study aims to investigate the clinical features of invasive community-acquired Staphylococcus aureus (CA-SA) infection in Chinese children and analyze its molecular features. METHODS:Clinical data and invasive CA-SA isolates were prospectively collected. Pediatric risk of mortality (PRISM) score was us...

journal_title：BMC infectious diseases

authors： Qiao Y,Ning X,Chen Q,Zhao R,Song W,Zheng Y,Dong F,Li S,Li J,Wang L,Zeng T,Dong Y,Yao K,Yu S,Yang Y,Shen X

更新日期：2014-11-07 00:00:00

abstract：BACKGROUND:Herpes simplex virus type-2 (HSV-2) is one of the most common sexually transmitted infections that facilitate human immunodeficiency virus (HIV) acquisition by over two fold or more. The development of HSV-2 control methods as a measure to control HIV epidemic in high HSV-2/HIV areas has become a priority. T...

journal_title：BMC infectious diseases

authors： Biswas D,Borkakoty B,Mahanta J,Walia K,Saikia L,Akoijam BS,Jampa L,Kharkongar A,Zomawia E

更新日期：2011-11-23 00:00:00

abstract：BACKGROUND:The parasite Entamoeba histolytica is the causal agent of amoebiasis, a worldwide emerging disease. Amebic brain abscess is a form of invasive amebiasis that is both rare and frequently lethal. This condition always begins with the infection of the colon by E. histolytica trophozoites, which subsequently tra...

journal_title：BMC infectious diseases

authors： Victoria-Hernández JA,Ventura-Saucedo A,López-Morones A,Martínez-Hernández SL,Medina-Rosales MN,Muñoz-Ortega M,Ávila-Blanco ME,Cervantes-García D,Barba-Gallardo LF,Ventura-Juárez J

更新日期：2020-09-14 00:00:00

abstract：BACKGROUND:The most frequent pathogen that causes bacterial meningitis is the Gram-positive bacterium Streptococcus (S.) pneumoniae. CCAAT/enhancer binding protein δ is a transcription factor that has recently been hypothesized to play a detrimental role in outcome of meningitis caused by S. pneumoniae. Here, we studie...

journal_title：BMC infectious diseases

authors： Duitman J,Valls Serón M,Engelen-Lee J,Brouwer MC,Spek CA,van de Beek D

更新日期：2016-11-11 00:00:00

abstract：BACKGROUND:Screening household contacts of active tuberculosis (TB) patients is recommended for TB control. Due to resource constraints this rarely occurs in lower income countries. Demographic and clinical features of index cases may influence the likelihood of onwards TB transmission. It has also been proposed that a...

journal_title：BMC infectious diseases

authors： Hector J,Anderson ST,Banda G,Kamdolozi M,Jefferys LF,Shani D,Garton NJ,Mwale A,Jobe A,Davies GR,Sloan DJ

更新日期：2017-04-11 00:00:00

abstract：BACKGROUND:The China-Myanmar border is a particularly interesting region that has very high prevalence of and considerable diversity of HIV-1 recombinants. Due to the transient nature of their work, long-distance truck drivers (LDTDs) have a comparatively high potential to become infected with HIV-1 and further spread ...

journal_title：BMC infectious diseases

authors： Zhou YH,Liang YB,Pang W,Qin WH,Yao ZH,Chen X,Zhang C,Zheng YT

更新日期：2014-08-26 00:00:00

abstract：BACKGROUND:Various viruses are known to be associated with pneumonia. However, the impact of viral infections on adult pneumonia mortality remains unclear. This study aimed to clarify the effect of virus infection on pneumonia mortality among adults stratified by virus type and patient comorbidities. METHODS:This mult...

journal_title：BMC infectious diseases

authors： Katsurada N,Suzuki M,Aoshima M,Yaegashi M,Ishifuji T,Asoh N,Hamashige N,Abe M,Ariyoshi K,Morimoto K,Adult Pneumonia Study Group-Japan.

更新日期：2017-12-06 00:00:00

abstract：BACKGROUND:The major infectious diseases of hepatitis B has constituted an acute public health challenge in China. An effective and affordable HBV control model is urgently needed. A national project of Community-based Collaborative Innovation HBV (CCI-HBV) demonstration areas has optimized the existing community healt...

journal_title：BMC infectious diseases

authors： Ruan B,Yu Z,Yang S,Xu K,Ren J,Yao J,Wu N,Yu C,Deng M,Xie T,Chen P,Wang C,Li Y,Zhao Y,Sheng J,Hou Y,Wu Z,Jin S,Chen Y,Li M,Zhu F,Tang H,Hao Y,Pang X,Lu L,Yang W,Yuan Z,Xu A,Li Z,Ni M,Yan Y,Zho

更新日期：2019-07-12 00:00:00

abstract：BACKGROUND:Systematic reviews suggest that the incidence of diagnosed tuberculosis is two- to- three times higher in those with diabetes mellitus than in those without. Few studies have previously reported the association between diabetes or hyperglycaemia and the prevalence of active tuberculosis and none in a populat...

journal_title：BMC infectious diseases

authors： Bailey SL,Ayles H,Beyers N,Godfrey-Faussett P,Muyoyeta M,du Toit E,Yudkin JS,Floyd S

更新日期：2016-12-05 00:00:00

abstract：BACKGROUND:Isoniazid (INH) represents the cornerstone for the treatment of cases infected with Mycobacterium tuberculosis (MTB) strains. Several molecular mechanisms have been shown to be the major causes for INH resistance, while the dynamic change of mutations conferring INH resistance among MTB strains during the pa...

journal_title：BMC infectious diseases

authors： Huo F,Lu J,Zong Z,Jing W,Shi J,Ma Y,Dong L,Zhao L,Wang Y,Huang H,Pang Y

更新日期：2019-08-05 00:00:00

abstract：BACKGROUND:Rituximab, a monoclonal antibody directed against CD20, is approved for the treatment of CD20-positive B-cell Non-Hodgkin's lymphoma and rheumatologic disorders. Due to its potent activity in depleting CD20-positive lymphocytes, the influence on opportunistic infections is still under discussion. Thus, we an...

journal_title：BMC infectious diseases

authors： Nissen JC,Hummel M,Brade J,Kruth J,Hofmann WK,Buchheidt D,Reinwald M

更新日期：2014-07-03 00:00:00

abstract：BACKGROUND:Carbapenemase-producing organisms (CPOs) have emerged as antibiotic-resistant bacteria of global concern. Here we assessed the performance of the Carba (beta) assay, a multiplex real-time PCR assay developed by SpeeDx for the detection of key carbapenemase-encoding genes: KPC, NDM, OXA-48-like, IMP-4-like, a...

journal_title：BMC infectious diseases

authors： Bordin A,Trembizki E,Windsor M,Wee R,Tan LY,Buckley C,Syrmis M,Bergh H,Cottrell K,Zowawi HM,Sidjabat HE,Harris PNA,Nimmo GR,Paterson DL,Whiley DM

更新日期：2019-07-02 00:00:00

abstract：BACKGROUND:In Creutzfeldt-Jakob disease (CJD) and other related transmissible spongiform encephalopathies it is critical to understand the various pathways by which the infectious agent spreads to different organs. METHODS:We injected a CJD agent into mice, either intracerebrally (ic) or intraperitoneally (ip) and mon...

journal_title：BMC infectious diseases

authors： Radebold K,Chernyak M,Martin D,Manuelidis L

更新日期：2001-01-01 00:00:00