A real-time PCR assay for rapid identification of inducible and acquired clarithromycin resistance in Mycobacterium abscessus.

abstract：BACKGROUND:Culturing has long been the gold standard for detecting aetiologic agents in bacterial infections. In some cases, however, culturing fails to detect the infection. To further investigate culture-negative samples, amplification and subsequent sequencing of the 16S rRNA gene is often applied. The aim of the pr...

journal_title：BMC infectious diseases

authors： Stavnsbjerg C,Frimodt-Møller N,Moser C,Bjarnsholt T

更新日期：2017-03-27 00:00:00

abstract：BACKGROUND:Tuberculosis (TB) is a major global health problem and remains the leading cause of morbidity and mortality in developing countries. Routinely used TB diagnostic methods, in most endemic areas, are time-consuming, often less-sensitive, expensive and inaccessible to most patients. Therefore, there is an urgen...

journal_title：BMC infectious diseases

authors： Bentaleb EM,Abid M,El Messaoudi MD,Lakssir B,Ressami EM,Amzazi S,Sefrioui H,Ait Benhassou H

更新日期：2016-09-27 00:00:00

abstract：BACKGROUND:The Belgian HIV epidemic is largely concentrated among men who have sex with men and Sub-Saharan Africans. We studied the continuum of HIV care of those diagnosed with HIV living in Belgium and its associated factors. METHODS:Data on new HIV diagnoses 2007-2010 and HIV-infected patients in care in 2010-2011...

journal_title：BMC infectious diseases

authors： Van Beckhoven D,Florence E,Ruelle J,Deblonde J,Verhofstede C,Callens S,Vancutsem E,Lacor P,Demeester R,Goffard JC,Sasse A,BREACH Belgian Research on AIDS and HIV Consortium.

更新日期：2015-11-03 00:00:00

abstract：BACKGROUND:Although a dramatic decrease in AIDS progression has been observed after Highly Active Anti Retroviral Therapy (HAART) in both low- and high-resource settings, few data support that fact in low-resource settings.This study describes the incidence of AIDS-defining illnesses (ADI) after HAART initiation and an...

journal_title：BMC infectious diseases

authors： De Beaudrap P,Etard JF,Diouf A,Ndiaye I,Ndèye GF,Sow PS,Ndèye KC,Ecochard R,Delaporte E,ANRS 1215 Study Group.

更新日期：2010-06-19 00:00:00

abstract：BACKGROUND:Routine culture-based diagnosis of Pseudomonas aeruginosa lung infection in Cystic Fibrosis (CF) patients can be hampered by the phenotypic variability of the microorganism, including its transition to a Viable But Non-Culturable (VBNC) state. The aim of this study was to validate an ecfX-targeting qPCR prot...

journal_title：BMC infectious diseases

authors： Mangiaterra G,Amiri M,Di Cesare A,Pasquaroli S,Manso E,Cirilli N,Citterio B,Vignaroli C,Biavasco F

更新日期：2018-12-27 00:00:00

abstract：BACKGROUND:Corynebacterium striatum is a member of the non-diphtherial corynebacteria, which are ubiquitous in nature and generally colonize the skin and mucous membranes of humans. Rarely, it causes infective endocarditis (IE). We report a case of rare left atrial bacterial vegetative mass due to C. striatum masquerad...

journal_title：BMC infectious diseases

authors： Xu J,Yang Q,Li J,Zheng X

更新日期：2017-05-26 00:00:00

abstract：BACKGROUND:Evaluating the completeness of tuberculosis (TB) notification data is important for monitoring of TB surveillance systems. We conducted an inventory study to calculate TB underreporting in Germany in 2013-2017. METHODS:Acquisition of two pseudonymized case-based data sources (national TB notification data a...

journal_title：BMC infectious diseases

authors： Domaszewska T,Karo B,Preuss U,Kollan C,Reuss A,Blank HP,Brodhun B,Hauer B,Altmann D,Fiebig L,Haas W,Perumal N

更新日期：2020-10-17 00:00:00

abstract：BACKGROUND:The potential impact of an influenza pandemic can be assessed by calculating a set of transmissibility parameters, the most important being the reproduction number (R), which is defined as the average number of secondary cases generated per typical infectious case. METHODS:We conducted a systematic review t...

journal_title：BMC infectious diseases

authors： Biggerstaff M,Cauchemez S,Reed C,Gambhir M,Finelli L

更新日期：2014-09-04 00:00:00

abstract：BACKGROUND:Tuberculosis remains a serious threat to human health as an infectious disease in China. Henan, a most populated province in China, has a high incidence of tuberculosis (TB). Though the genetic diversity of Mycobacterium tuberculosis (MTB) has been investigated in many regions, there have been only a few stu...

journal_title：BMC infectious diseases

authors： Shi J,Zheng D,Zhu Y,Ma X,Wang S,Li H,Xing J

更新日期：2018-09-03 00:00:00

abstract：BACKGROUND:Antiretroviral therapy (ART) markedly reduces HIV transmission, and testing and treatment programs have been advocated as a method for decreasing transmission at the population level. Little is known, however, about the extent to which sexually transmitted infections (STIs), which increase the HIV infectious...

journal_title：BMC infectious diseases

authors： Champredon D,Bellan SE,Delva W,Hunt S,Shi CF,Smieja M,Dushoff J

更新日期：2015-06-30 00:00:00

abstract：BACKGROUND:In vitro data suggests that suboptimal initial vancomycin exposure may select for heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) infections. However, no clinical studies have evaluated the relationship between initial vancomycin exposure and emergence of hVISA. This pilot study seeks to ...

journal_title：BMC infectious diseases

authors： Martirosov DM,Bidell MR,Pai MP,Scheetz MH,Rosenkranz SL,Faragon C,Malik M,Mendes RE,Jones RN,McNutt LA,Lodise TP

更新日期：2017-08-02 00:00:00

abstract：BACKGROUND:Low absolute humidity (AH) has been associated with increased influenza virus survival and transmissibility and the onset of seasonal influenza outbreaks. Humidification of indoor environments may mitigate viral transmission and may be an important control strategy, particularly in schools where viral transm...

journal_title：BMC infectious diseases

authors： Koep TH,Enders FT,Pierret C,Ekker SC,Krageschmidt D,Neff KL,Lipsitch M,Shaman J,Huskins WC

更新日期：2013-02-05 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis is an inflammatory disorder in which the role of bacteria remains uncertain. While sinus outflow obstruction is often an initiating event, mucosal inflammation and dysbiosis may persist or develop in sinuses with widely patent surgical openings. Understanding of the relationship betwee...

journal_title：BMC infectious diseases

authors： Koutsourelakis I,Halderman A,Khalil S,Hittle LE,Mongodin EF,Lane AP

更新日期：2018-08-30 00:00:00

abstract：BACKGROUND:Members of Shewanella species are opportunistic pathogens that are found in marine environments. Currently more than sixty species have been identified, whereas the most commonly clinical cases associated with Shewanella species have involved only two species, i.e., S. algae and S. putrefaciens. We present t...

journal_title：BMC infectious diseases

authors： Zhang F,Fang Y,Pang F,Liang S,Lu X,Kan B,Xu J,Zhao J,Du Y,Wang D

更新日期：2018-09-05 00:00:00

abstract：BACKGROUND:Miliary tuberculosis (TB) is an uncommon cause of acute respiratory distress syndrome (ARDS) with a high mortality. The aim of the present study was to evaluate the clinical characteristics, predictors and outcome of patients with ARDS caused by miliary TB. METHODS:A retrospective study was conducted among ...

journal_title：BMC infectious diseases

authors： Deng W,Yu M,Ma H,Hu LA,Chen G,Wang Y,Deng J,Li C,Tong J,Wang DX

更新日期：2012-05-20 00:00:00

abstract：BACKGROUND:Brucella abortus is a highly pathogenic zoonotic agent, tempting for the development of a rapid diagnostic method to enable adequate treatment and prevent further spread. Enrichment of the bacteria is often used as a first step in diagnostics to increase the bacterial number above the detection limit of the ...

journal_title：BMC infectious diseases

authors： Kaden R,Ferrari S,Jinnerot T,Lindberg M,Wahab T,Lavander M

更新日期：2018-06-05 00:00:00

abstract：BACKGROUND:Viral central nervous system (CNS) infections are common in countries where malaria is endemic but, due to limited laboratory facilities, few studies have systematically examined the prevalence and clinical consequences of the presence of viruses in cerebrospinal fluid (CSF) from children with suspected CNS ...

journal_title：BMC infectious diseases

authors： Laman M,Hwaiwhanje I,Bona C,Warrel J,Aipit S,Smith D,Noronha J,Siba P,Mueller I,Betuela I,Davis TM,Manning L

更新日期：2014-11-26 00:00:00

abstract：BACKGROUND:This study aims to investigate the clinical features of invasive community-acquired Staphylococcus aureus (CA-SA) infection in Chinese children and analyze its molecular features. METHODS:Clinical data and invasive CA-SA isolates were prospectively collected. Pediatric risk of mortality (PRISM) score was us...

journal_title：BMC infectious diseases

authors： Qiao Y,Ning X,Chen Q,Zhao R,Song W,Zheng Y,Dong F,Li S,Li J,Wang L,Zeng T,Dong Y,Yao K,Yu S,Yang Y,Shen X

更新日期：2014-11-07 00:00:00

abstract：BACKGROUND:The accuracy of a new optical biosensor (OB) point-of-care device for the detection of severe infections is studied. METHODS:The OB emits different wavelengths and outputs information associated with heart rate, pulse oximetry, levels of nitric oxide and kidney function. At the first phase, recordings were ...

journal_title：BMC infectious diseases

authors： Doulou S,Leventogiannis K,Tsilika M,Rodencal M,Katrini K,Antonakos N,Kyprianou M,Karofylakis E,Karageorgos A,Koufargyris P,Christopoulos G,Kassianidis G,Stamatelopoulos K,Newberry R,Giamarellos-Bourboulis EJ

更新日期：2020-11-19 00:00:00

abstract：BACKGROUND:Although breast-feeding accounts for 15-20% of mother-to-child transmission (MTCT) of HIV, it is not prohibited in some developing countries because of the higher mortality associated with not breast-feeding. We assessed the potential impact, on HIV infection and infant mortality, of a recommendation for sho...

journal_title：BMC infectious diseases

authors： Atashili J,Kalilani L,Seksaria V,Sickbert-Bennett EE

更新日期：2008-05-16 00:00:00

abstract：BACKGROUND:Because of the high prevalence and absence of cure for infection, chronic hepatitis B virus (HBV) infection has been acknowledged as a pressing public health issue. Toll-like receptors (TLRs) activate the human innate immune system and the polymorphisms in TLRs may alter their function. The present study aim...

journal_title：BMC infectious diseases

authors： Lin Y,Gao ZX,Shen X,Chen MJ,Li YT,Li SL,Lin HL,Zhao QF,Liu F,Niu JJ

更新日期：2018-01-10 00:00:00

abstract：BACKGROUND:Poor outcomes of invasive candidiasis (IC) are associated with the difficulty in establishing the microbiological diagnosis at an early stage. New scores and laboratory tests have been developed in order to make an early therapeutic intervention in an attempt to reduce the high mortality associated with inva...

journal_title：BMC infectious diseases

authors： Pemán J,Zaragoza R,Quindós G,Alkorta M,Cuétara MS,Camarena JJ,Ramírez P,Giménez MJ,Martín-Mazuelos E,Linares-Sicilia MJ,Pontón J,study group Candida albicans Germ Tube Antibody Detection in Critically Ill Patients.

更新日期：2011-03-09 00:00:00

abstract：BACKGROUND:Tuberculosis (TB) is the major cause of death in Human Immunodeficiency Virus (HIV)-infected individuals. However, diagnosis of TB in HIV remains challenging particularly when HIV infection is advanced. Several gene signatures and serum protein biomarkers have been identified that distinguish active TB from ...

journal_title：BMC infectious diseases

authors： Verma S,Du P,Nakanjako D,Hermans S,Briggs J,Nakiyingi L,Ellner JJ,Manabe YC,Salgame P

更新日期：2018-05-15 00:00:00

abstract：BACKGROUND:Seroreactivity, processes of seroconversion and seroreversion, in the context of HPV infection has been investigated in numerous studies. However, the data resulting from these studies are usually not accounted for in mathematical transmission models of various HPV types due to gaps in our understanding of t...

journal_title：BMC infectious diseases

authors： Korostil IA,Garland SM,Law MG,Regan DG

更新日期：2013-02-13 00:00:00

abstract：BACKGROUND:The different laboratory methods used in the diagnosis of congenital toxoplasmosis have variable sensitivity and specificity. There is no evidence to prove that maternal treatment reduces the risk of fetal infection. The purpose of this study was to assess methods for the confirmation of congenital toxoplasm...

journal_title：BMC infectious diseases

authors： Rodrigues IM,Costa TL,Avelar JB,Amaral WN,Castro AM,Avelino MM

更新日期：2014-06-24 00:00:00

abstract：BACKGROUND:Prion diseases are caused by the accumulation of an aberrantly folded isoform of the prion protein, designated PrPSc. In a cell-based assay, quinacrine inhibits the conversion of normal host prion protein (PrPC) to PrPSc at a half-maximal concentration of 300 nM. While these data suggest that quinacrine may ...

journal_title：BMC infectious diseases

authors： Yung L,Huang Y,Lessard P,Legname G,Lin ET,Baldwin M,Prusiner SB,Ryou C,Guglielmo BJ

更新日期：2004-11-29 00:00:00

abstract：BACKGROUND:Although live-attenuated varicella-zoster virus (VZV) vaccines have been proven to be safe and effective in preventing varicella and real-word evidence shows routine childhood immunization programs are effective in dramatically reducing varicella associated morbidity and mortality, varicella vaccine is not i...

journal_title：BMC infectious diseases

authors： Meszner Z,Molnar Z,Rampakakis E,Yang HK,Kuter BJ,Wolfson LJ

更新日期：2017-07-14 00:00:00

abstract：BACKGROUND:Group B streptococcus (GBS) is reported as the leading cause of neonatal sepsis and meningitis. Newborns from GBS colonized pregnant women are at high risk of infection. METHOD:A Hospital based cross-sectional study was conducted at Hawassa University Comprehensive Specialized Hospital from November 05, 201...

journal_title：BMC infectious diseases

authors： Ali MM,Woldeamanuel Y,Woldetsadik DA,Chaka TE,Fenta DA,Dinberu MT,Weldetensaye EK,Ismael SJ,Tadesse BT

更新日期：2019-04-16 00:00:00

abstract：BACKGROUND:Non-organ-specific autoantibodies are found in a considerable number of anti-HCV positive patients. Previous studies investigated the clinical relevance of these antibodies in patients treated with interferon monotherapy, but not combination therapies. METHODS:Anti-nuclear, anti-smooth muscle, anti-mitochon...

journal_title：BMC infectious diseases

authors： Wasmuth HE,Stolte C,Geier A,Dietrich CG,Gartung C,Lorenzen J,Matern S,Lammert F

更新日期：2004-02-13 00:00:00

abstract：BACKGROUND:Varicella is normally a self-limited childhood disease caused by varicella-zoster virus infection. However, it sometimes causes severe diseases, especially in immunocompromised individuals. We report a case of severe varicella in a young woman. CASE PRESENTATION:A 19-year-old woman presented to the emergenc...

journal_title：BMC infectious diseases

authors： Zhang W,Ruan QL,Yan F,Hu YK

更新日期：2020-01-17 00:00:00