Atypical Herpes simplex keratitis (HSK) presenting as a perforated corneal ulcer with a large infiltrate in a contact lens wearer: multinucleated giant cells in the Giemsa smear offered a clue to the diagnosis.

abstract：BACKGROUND:To study the therapeutic effect of bone marrow-derived mesenchymal stem cells (BMSC) against retinal neovascularization and to compare with anti-vascular endothelial growth factor (VEGF) therapy. METHODS:Neonatal C57BL/6 mice were exposed in hyperoxygen and returned to room air to develop oxygen-induced ret...

journal_title：BMC ophthalmology

authors： Xu W,Cheng W,Cui X,Xu G

更新日期：2020-01-06 00:00:00

abstract：BACKGROUND:To assess the reliability of the measurements obtained with the PalmScan, when compared with another standardized A-mode ultrasound device, and assess the consistency and correlation between the two methods. METHODS:Transversal, descriptive, and comparative study. We recorded the axial length (AL), anterior...

journal_title：BMC ophthalmology

authors： Velez-Montoya R,Shusterman EM,López-Miranda MJ,Mayorquin-Ruiz M,Salcedo-Villanueva G,Quiroz-Mercado H,Morales-Cantón V

更新日期：2010-03-24 00:00:00

abstract：BACKGROUND:Classification of optical coherence tomography (OCT) images can be achieved with high accuracy using classical convolution neural networks (CNN), a commonly used deep learning network for computer-aided diagnosis. Classical CNN has often been criticized for suppressing positional relations in a pooling layer...

journal_title：BMC ophthalmology

authors： Tsuji T,Hirose Y,Fujimori K,Hirose T,Oyama A,Saikawa Y,Mimura T,Shiraishi K,Kobayashi T,Mizota A,Kotoku J

更新日期：2020-03-19 00:00:00

abstract：BACKGROUND:Refraction change of silicone oil (SO) tamponade in phakic and aphakic eye has been studied thoroughly; however, it is rarely studied in pseudophakic eye. In this paper we aimed to deduce a theoretical formula predicting refractive shift of silicone oil tamponade in pseudophakic eye and compared it with clin...

journal_title：BMC ophthalmology

authors： Fang W,Li J,Jin X,Zhai J,Dai Y,Li Y

更新日期：2016-08-16 00:00:00

abstract：BACKGROUND:Fungal keratitis is difficult to treat that can result in corneal blindness requiring penetrating keratoplasty and in fungal endothalmitis. We report a case of fungal keratitis and onychomycosis simultaneously infected by Trichophyton. CASE PRESENTATION:A 77-year old male presented with ocular pain, conjunc...

journal_title：BMC ophthalmology

authors： Jin KW,Jeon HS,Hyon JY,Wee WR,Suh W,Shin YJ

更新日期：2014-07-11 00:00:00

abstract：BACKGROUND:Recently, instruments for the measurement of wavefront aberration in the living human eye have been widely available for clinical applications. Despite the extensive background experience on wavefront sensing for research purposes, the information derived from such instrumentation in a clinical setting shoul...

journal_title：BMC ophthalmology

authors： Ginis HS,Plainis S,Pallikaris A

更新日期：2004-02-11 00:00:00

abstract：BACKGROUND:To present the follow-up outcomes of a modified technique of transscleral suture fixation of posterior chamber intraocular lens (PCIOL) in eyes with inadequate capsule support. METHODS:A retrospective chart review of 21 patients underwent transscleral suture fixation of a foldable 3-looped haptics one-piece...

journal_title：BMC ophthalmology

authors： Ni S,Wang W,Chen X,Wu X,He S,Ma Y,Xu W

更新日期：2019-05-09 00:00:00

abstract：BACKGROUND:The performance of glaucoma diagnostic systems could be conceivably improved by the integration of functional and structural test measurements that provide relevant and complementary information for reaching a diagnosis. The purpose of this study was to investigate the performance of data fusion methods and ...

journal_title：BMC ophthalmology

authors： Bizios D,Heijl A,Bengtsson B

更新日期：2011-08-04 00:00:00

abstract：BACKGROUND:To investigate the expression and significance of mechanistic target of rapamycin complex 1(mTORC1) in diabetic retinopathy (DR), and to find new targets and new methods for the treatment of DR. METHODS:A DR rat model was prepared by general feeding combined with intraperitoneal injection of 10% streptozoto...

journal_title：BMC ophthalmology

authors： Liu Y,Zheng Y,Zhou Y,Liu Y,Xie M,Meng W,An M

更新日期：2020-07-20 00:00:00

abstract：BACKGROUND:Although the association between metabolic syndrome and intraocular pressure is well known, the relationship between the intraocular pressure and different combination of the components of metabolic syndrome has not been actively researched yet. The study aimed to investigate the relationship between the int...

journal_title：BMC ophthalmology

authors： Son J,Koh H,Son J

更新日期：2016-06-06 00:00:00

abstract：BACKGROUND:To describe the characteristics of patients with syphilitic uveitis in northern China. METHODS:A case series of 21 patients (33 eyes) diagnosed with syphilitic uveitis from 2011 to 2016 at a tertiary center in northern China was retrospectively analyzed. RESULTS:Twenty-one patients (33 eyes) were diagnosed...

journal_title：BMC ophthalmology

authors： Zhang X,Du Q,Ma F,Lu Y,Wang M,Li X

更新日期：2017-06-19 00:00:00

abstract：BACKGROUND:Immunoglobulin G4-related disease (IgG4-rd) is characterized by lymphoplasmacytic infiltration and tissue fibrosis. Orbital manifestations of IgG4-rd may include unilateral or bilateral proptosis, cicatricial extraocular muscle myopathy, orbital inflammation and pain which may mimic ophthalmic Graves' diseas...

journal_title：BMC ophthalmology

authors： Erdei A,Steiber Z,Molnar C,Berenyi E,Nagy EV

更新日期：2018-01-12 00:00:00

abstract：BACKGROUND:Adolescent KC is a special segment of the general KC population because an adolescents's eyes are still susceptible to blurred vision and optical defocus during the sensitive period of ocular and visual development. In the present study, we evaluated the ocular dimensions of 53 KC adolescents. METHODS:One h...

journal_title：BMC ophthalmology

authors： Jian W,Shen Y,Chen Y,Tian M,Zhou X

更新日期：2018-02-13 00:00:00

abstract：BACKGROUND:Numerous studies have suggested that the integrity of the cone interdigitation zone (IZ) could be considered to be a marker of photoreceptor damage and its recovery. However, little is known about the IZ in healthy eyes. Our present study was to measure the cone IZ area by optical coherence tomography (OCT),...

journal_title：BMC ophthalmology

authors： Gu R,Deng G,Jiang Y,Jiang C,Xu G

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The current study compared optical quality before and after implantation of a posterior chamber phakic intraocular lens with a central hole [V4c implantable collamer lens (ICL)] under bright and dark lighting conditions by means of the Optical Quality Analysis System™ (OQAS; Visiometrics, Terrassa, Spain). ...

journal_title：BMC ophthalmology

authors： He T,Zhu Y,Zhou J

更新日期：2020-03-04 00:00:00

abstract：BACKGROUND:To evaluate the retinal function before and soon after an intravitreal injection of an anti-vascular endothelial growth factor (anti-VEGF) agents. METHODS:Seventy-nine eyes of 79 patients that were treated by an intravitreal injection of an anti-VEGF agent for age-related macular degeneration (AMD), diabeti...

journal_title：BMC ophthalmology

authors： Terauchi G,Shinoda K,Sakai H,Kawashima M,Matsumoto CS,Mizota A,Miyake Y

更新日期：2019-06-17 00:00:00

abstract：BACKGROUND:A cyclodialysis cleft often leads to direct communication between the anterior chamber and the suprachoroidal space. It is a rare condition that is encountered with blunt trauma, and less commonly, after surgery. Hypotony is the major sequelae that may lead to hypotonous maculopathy, optic disc edema, cornea...

journal_title：BMC ophthalmology

authors： Bair H,Lin CJ,Lai CT,Hsia NY,Tsai YY

更新日期：2020-03-23 00:00:00

abstract：BACKGROUND:There is no generally accepted medical or surgical treatment to stop the progressive course of retinitis pigmentosa. Previous studies have suggested lutein as a potential treatment with positive effects on macular pigment density. The objective of this study was to examine the effect of lutein supplementatio...

journal_title：BMC ophthalmology

authors： Bahrami H,Melia M,Dagnelie G

更新日期：2006-06-07 00:00:00

abstract：BACKGROUND:Congenital cataract is the most frequent cause of blindness during infancy or early childhood. To date, more than 40 loci associated with congenital cataract have been identified, including at least 26 genes on different chromosomes associated with inherited cataract. This present study aimed to identify the...

journal_title：BMC ophthalmology

authors： Shen C,Wang J,Wu X,Wang F,Liu Y,Guo X,Zhang L,Cao Y,Cao X,Ma H

更新日期：2017-05-19 00:00:00

abstract：BACKGROUND:To investigate the ability of characterizing neonatal retinal hemorrhage (RH) using RetCam in healthy newborns and the systemic effects during the procedure. METHODS:This prospective study enrolled 68 healthy newborns aged 2 to 4 days old. The RH was imaged and classified according to the location and numbe...

journal_title：BMC ophthalmology

authors： Chen F,Cheng D,Pan J,Huang C,Cai X,Tian Z,Lu F,Shen L

更新日期：2018-08-20 00:00:00

abstract：BACKGROUND:To analyze the clinical characteristics, treatment and prognosis of children with unilateral retinoblastoma (RB) and intracranial segment of retrobulbar optic nerve invasion. METHODS:A total of 14 children with unilateral RB and intracranial segment of retrobulbar optic nerve invasion were enrolled in this ...

journal_title：BMC ophthalmology

authors： Wang YZ,Zhang Y,Huang DS,Shi JT,Ma JM,Li B,Xu XL,Zhou Y,Gu HL

更新日期：2021-01-14 00:00:00

abstract：BACKGROUND:Retinoblastoma (RB) is the most frequent pediatric retinal tumor. In the present study, to elucidate chemoresistance mechanisms and identify potential biomarkers in RB, we utilized RNA sequencing (RNAseq) technological platforms to reveal transcriptome profiles and identify any differentially expressed genes...

journal_title：BMC ophthalmology

authors： Song WP,Zheng S,Yao HJ,Zhou XF,Li R,Zhang CY,Zhao JY,Wang LW,Shao RG,Li L

更新日期：2020-03-06 00:00:00

abstract：BACKGROUND:A patient's health literacy is fundamental for navigating the health system and managing disease. This study aimed to compare the health literacy levels of patients with chronic retinal disease in Denmark. METHODS:This cross-sectional questionnaire study used the validated HLS-EU-Q16 questionnaire to determ...

journal_title：BMC ophthalmology

authors： Jandorf S,Krogh Nielsen M,Sørensen K,Sørensen TL

更新日期：2019-08-08 00:00:00

abstract：BACKGROUND:Thrombotic thrombocytopenic purpura (TTP) is a life-threatening hematological condition associated with deficiency in ADAMTS13. Ocular manifestations associated with TTP are uncommon. CASE PRESENTATION:Here we report a case where a 44 year old female patient with a history of symptomatic anemia and cotton w...

journal_title：BMC ophthalmology

authors： Bandara AGNMK,Matthias AT

更新日期：2020-11-19 00:00:00

abstract：BACKGROUND:Glaucoma is a progressive disease responsible for the second commonest cause of blindness in the UK. Identifying appropriate patients for hospital care remains an ongoing challenge for all UK hospital glaucoma services. The purpose of our study is to evaluate accuracy and outcome of community optometry refer...

journal_title：BMC ophthalmology

authors： El-Assal K,Foulds J,Dobson S,Sanders R

更新日期：2015-12-07 00:00:00

abstract：BACKGROUND:This study compared the postoperative outcomes of 27-gauge (G) and 25-G vitrectomy performed for the treatment of idiopathic epiretinal membrane (ERM). METHODS:The study design was single center, retrospective, interventional case series. Two hundred consecutive eyes that underwent primary vitrectomy for ER...

journal_title：BMC ophthalmology

authors： Naruse S,Shimada H,Mori R

更新日期：2017-10-10 00:00:00

abstract：BACKGROUND:To determine the rate of glaucoma following congenital cataract surgery at Moorfields Eye Hospital (MEH), and to investigate potential risk factors for glaucoma in our case series. METHODS:A retrospective case notes review was undertaken of all congenital cataract lensectomies performed at MEH between 1994 ...

journal_title：BMC ophthalmology

authors： Michaelides M,Bunce C,Adams GG

更新日期：2007-09-11 00:00:00

abstract：BACKGROUND:The use of capsular tension ring (CTR) implantation to treat cataract patients with weak zonules is still controversial. The aim of this study was to examine the effects of CTR implantation on capsular stability after phacoemulsification in patients with weak zonules, especially patients who have undergone p...

journal_title：BMC ophthalmology

authors： Yang S,Jiang H,Nie K,Feng L,Fan W

更新日期：2021-01-07 00:00:00

abstract：BACKGROUND:To evaluate the correlation between visual acuity improvement and vision-related QOL after ranibizumab treatment in Japanese patients with AMD. METHODS:In this one-year prospective, interventional, open-label, multicenter study involving four sites, patients with neovascular AMD were enrolled and observed f...

journal_title：BMC ophthalmology

authors： Oshima Y,Ishibashi Y,Umeda N,Nagata T,Yoshida S,Uchio E,Kondo H,Sonoda KH,Ishibashi T

更新日期：2021-01-23 00:00:00

abstract：BACKGROUND:Perfluorocarbon liquid (PFCL) is widely used as an intraoperative heavy tamponade to flatten the retina and is replaced with silicone oil (SO) at the end of the surgery. Due to the long tamponade period, the SO is known to remain attached to the retina at the time of removal, and is commonly termed "sticky o...

journal_title：BMC ophthalmology

authors： Fukumoto M,Nishida Y,Kida T,Sato T,Kobayashi T,Ikeda T

更新日期：2018-03-27 00:00:00