Atypical Herpes simplex keratitis (HSK) presenting as a perforated corneal ulcer with a large infiltrate in a contact lens wearer: multinucleated giant cells in the Giemsa smear offered a clue to the diagnosis.

Abstract:

PURPOSE:To report a case of atypical herpes simplex keratitis initially diagnosed as bacterial keratitis, in a contact lens wearer. RESULTS:Case report of an 18-year-old woman using contact lenses who presented with pain, redness and gradual decrease in vision in the right eye. Examination revealed a paracentral large stromal infiltrate with a central 2-mm perforation. Corneal and conjunctival scrapings were collected for microbiological investigations. Corneal tissue was obtained following penetrating keratoplasty. Corneal scraping revealed no microorganisms. Giemsa stained smear showed multinucleated giant cells. Conjunctival, corneal scrapings and tissue were positive for herpes simplex virus - 1 (HSV) antigen. Corneal tissue was positive for HSV DNA by PCR. CONCLUSIONS:Atypical HSV keratitis can occur in contact lens wearers. A simple investigation like Giemsa stain may offer a clue to the diagnosis.

journal_name

BMC Ophthalmol

journal_title

BMC ophthalmology

authors

Athmanathan S,Pranesh VM,Pasricha G,Garg P,Vemuganti GK,Sharma S

doi

10.1186/1471-2415-1-1

keywords:

subject

Has Abstract

pub_date

2001-01-01 00:00:00

pages

1

issn

1471-2415

journal_volume

1

pub_type

杂志文章
  • The effects of oral and topical corticosteroid in rabbit corneas.

    abstract:BACKGROUND:To determine the most effective route of administration of corticosteroids in the treatment of ocular surface disease, by characterizing the difference between oral prednisolone and topical dexamethasone administration using an animal model. METHODS:Pharmacokinetic analyses determined the corticosteroid con...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-016-0339-5

    authors: Araki-Sasaki K,Katsuta O,Mano H,Nagano T,Nakamura M

    更新日期:2016-09-05 00:00:00

  • A real-world study of effectiveness of intravitreal bevacizumab and ranibizumab injection for treating retinal diseases in Thailand.

    abstract:BACKGROUND:To evaluate the effectiveness of intravitreal bevacizumab (IVB) and intravitreal ranibizumab (IVR) in actual practice for treating patients with retinal diseases in Thailand. METHODS:A prospective, multi-centre, observational study was conducted among eight hospitals in their ophthalmology outpatient depart...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s12886-019-1086-1

    authors: Kumluang S,Ingsrisawang L,Sangroongruangsri S,Chaikledkaew U,Ratanapakorn T,Ruamviboonsuk P,Taweebanjongsin W,Choovuthayakorn J,Thoongsuwan S,Hanutsaha P,Kulvichit K,Ratanapojnard T,Wongsawad W,Leelahavarong P,Teerawattananon

    更新日期:2019-03-29 00:00:00

  • Hyperreflective foci in OCT image as a biomarker of poor prognosis in diabetic macular edema patients treating with Conbercept in China.

    abstract:PURPOSE:To investigate the dynamic changes of hyperreflective foci (HF) in diabetic macular edema (DME) patients during the intravitreal Conbercept treatment in China. METHODS:DME Patients receiving intravitreal Conbercept (IVC) injections during the year 2016-2017 were retrospectively investigated. Thirteen patients ...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-019-1168-0

    authors: Liu S,Wang D,Chen F,Zhang X

    更新日期:2019-07-23 00:00:00

  • Ratios for double silicone oil Endotamponade - in vitro observations may assist with ratio selection.

    abstract:BACKGROUND:Silicone oil tamponade is more frequently reserved for cases of complex retinal detachment. We describe the effects of different variations in oil ratios with the relatively unknown technique of double oil tamponade. METHODS:Retrospective case note review of nine patients with complex rhegmatogenous retinal...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-017-0660-7

    authors: MacGregor C,Jonas A,Hanifudin A,Lochhead J

    更新日期:2017-12-28 00:00:00

  • Dolosigranulum pigrum keratitis: a three-case series.

    abstract:BACKGROUND:Dolosigranulum pigrum is a commensal inhabitant of the upper respiratory tract suspected to be responsible for ocular infections but no well-described case of D. pigrum corneal infection has been reported. Herein culture and PCR-sequencing-based investigations of corneal scraping specimens confirmed D. pigru...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/1471-2415-13-31

    authors: Sampo M,Ghazouani O,Cadiou D,Trichet E,Hoffart L,Drancourt M

    更新日期:2013-07-10 00:00:00

  • A novel approach to glaucoma screening and education in Nepal.

    abstract:BACKGROUND:Glaucoma is a major cause of blindness worldwide and an increasingly significant global health problem. Glaucoma prevention and management efforts have been challenging due to inherent difficulty in developing a simple and cost-effective screening plan, limited access to health care and educational resources...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/1471-2415-8-21

    authors: Thapa SS,Kelley KH,Rens GV,Paudyal I,Chang L

    更新日期:2008-10-26 00:00:00

  • The healing effect of the collagen-glycosaminoglycan copolymer on corneal thinning.

    abstract:BACKGROUND:To study the healing processes of partial thickness wounds in the adult rabbit cornea after grafting a porous collagen-glycosaminoglycan copolymer matrix (CG). METHODS:In this study, the regeneration of surgically-induced rabbit corneal defect implanted with CG was investigated. The corneal partial thicknes...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-018-0947-3

    authors: Wu SY,Pan CY,Shen EP,Tzeng IS,Hsu WC

    更新日期:2018-10-25 00:00:00

  • Low vision due to cerebral visual impairment: differentiating between acquired and genetic causes.

    abstract:BACKGROUND:To gain more insight into genetic causes of cerebral visual impairment (CVI) in children and to compare ophthalmological findings between genetic and acquired forms of CVI. METHODS:The clinical data of 309 individuals (mainly children) with CVI, and a visual acuity ≤ 0.3 were analyzed for etiology and ocula...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/1471-2415-14-59

    authors: Bosch DG,Boonstra FN,Willemsen MA,Cremers FP,de Vries BB

    更新日期:2014-05-01 00:00:00

  • Incidence of new coding for dry eye and ocular infection in open-angle glaucoma and ocular hypertension patients treated with prostaglandin analogs: retrospective analysis of three medical/pharmacy claims databases.

    abstract:BACKGROUND:To investigate the clinical relevance of two different preservative formulations, we compared 1-year incidence rates of additional coding of dry eye, ocular infection, or ocular surface disease (either dry eye or ocular infection) in open-angle glaucoma and ocular hypertension patients newly treated with lat...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/1471-2415-11-14

    authors: Schwartz GF,Kotak S,Mardekian J,Fain JM

    更新日期:2011-06-14 00:00:00

  • Influence of virtual reality on visual parameters: immersive versus non-immersive mode.

    abstract:BACKGROUND:To investigate the differences in refraction, accommodative factors, visual parameters, and subjective symptoms after using two types of virtual reality (VR) content with different depths of perception. METHODS:Twenty-three volunteers, who played VR games in two modes (immersive and non-immersive) for 30 mi...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-020-01471-4

    authors: Yoon HJ,Kim J,Park SW,Heo H

    更新日期:2020-05-24 00:00:00

  • A comparative study of glaucoma referrals in Southeast Scotland: effect of the new general ophthalmic service contract, Eyecare integration pilot programme and NICE guidelines.

    abstract:BACKGROUND:Glaucoma is a progressive disease responsible for the second commonest cause of blindness in the UK. Identifying appropriate patients for hospital care remains an ongoing challenge for all UK hospital glaucoma services. The purpose of our study is to evaluate accuracy and outcome of community optometry refer...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-015-0161-5

    authors: El-Assal K,Foulds J,Dobson S,Sanders R

    更新日期:2015-12-07 00:00:00

  • Factors associated with the occurrence of a fall in subjects with primary open-angle glaucoma.

    abstract:BACKGROUND:The aim of the study is to investigate risk factors for future falls in subject with primary open angle glaucoma (POAG). METHODS:All participants answered the following question at their baseline ophthalmic examination: Have you had any falls in the last year? (Yes/No). All study participants answered the s...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-017-0613-1

    authors: Adachi S,Yuki K,Awano-Tanabe S,Ono T,Murata H,Asaoka R,Tsubota K

    更新日期:2017-11-25 00:00:00

  • Correction to: Lhasa childhood eye study: the rationale, methodology, and baseline data of a 5 year follow-up of school-based cohort study in the Tibetan plateau region of Southwest China.

    abstract::An amendment to this paper has been published and can be accessed via the original article. ...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章,已发布勘误

    doi:10.1186/s12886-020-01572-0

    authors: Chen W,Fu J,Meng Z,Li L,Su H,Dai W,Yao Y

    更新日期:2020-07-31 00:00:00

  • Protection of retinal function and morphology in MNU-induced retinitis pigmentosa rats by ALDH2: an in-vivo study.

    abstract:BACKGROUND:Retinitis pigmentosa (RP) is a kind of inherited retinal degenerative diseases characterized by the progressive loss of photoreceptors. RP has been a conundrum without satisfactory countermeasures in clinic until now. Acetaldehyde dehydrogenase 2 (ALDH2), a major enzyme involved in aldehyde detoxification, h...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-020-1330-8

    authors: Yan W,Long P,Wei D,Yan W,Zheng X,Chen G,Wang J,Zhang Z,Chen T,Chen M

    更新日期:2020-02-18 00:00:00

  • Association of lifestyle and body structure to ocular axial length in Japanese elementary school children.

    abstract:BACKGROUND:The purpose of this study is to determine whether the lifestyle and body stature are significantly associated with the axial length (AL) of the eyes of Japanese third grade students. METHODS:A prospective, cross sectional, observational study was performed on 122 third grade students consisting of 61 boys a...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-017-0519-y

    authors: Terasaki H,Yamashita T,Yoshihara N,Kii Y,Sakamoto T

    更新日期:2017-07-12 00:00:00

  • Injections frequency and health care costs in patients treated with aflibercept compared to ranibizumab: new real-life evidence from Switzerland.

    abstract:BACKGROUND:Previous analyses of real-life data indicated that injection frequency and health care costs did not differ for anti-VEGF treatment with aflibercept and ranibizumab. The objective of this study was to investigate whether this finding persisted when analysing a longer time period after licensing. METHODS:Ret...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-017-0617-x

    authors: Reich O,Schmid MK,Rapold R,Bachmann LM,Blozik E

    更新日期:2017-12-04 00:00:00

  • Clinical characteristics, treatment and prognosis of children with unilateral retinoblastoma and intracranial segment of Retrobulbar optic nerve invasion.

    abstract:BACKGROUND:To analyze the clinical characteristics, treatment and prognosis of children with unilateral retinoblastoma (RB) and intracranial segment of retrobulbar optic nerve invasion. METHODS:A total of 14 children with unilateral RB and intracranial segment of retrobulbar optic nerve invasion were enrolled in this ...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-020-01768-4

    authors: Wang YZ,Zhang Y,Huang DS,Shi JT,Ma JM,Li B,Xu XL,Zhou Y,Gu HL

    更新日期:2021-01-14 00:00:00

  • Longitudinal study on visual outcome and spectacle use after intracapsular cataract extraction in northern India.

    abstract:PURPOSE:More than 3 million cataract extractions are undertaken in India annually. Almost 60% of these operations are intracapsular Cataract Extractions. The subsequent optical correction is provided by aphakic spectacles. The aim of this study is to assess visual outcome and perceived benefits of post-operative use of...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/1471-2415-3-9

    authors: Gupta SK,Murthy GV,Sharma N

    更新日期:2003-07-28 00:00:00

  • Analysis of intraocular positions of posterior implantable collamer lens by full-scale ultrasound biomicroscopy.

    abstract:BACKGROUND:To analyze the positions of intraocular posterior Implantable Collamer Lens (ICL) and its possible relationship with vault. METHODS:This cross-sectional study included 72 patients with high myopia (134 eyes) who were followed up after phakic intraocular lens implantation. The postoperative time ranged from ...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-018-0783-5

    authors: Zhang X,Chen X,Wang X,Yuan F,Zhou X

    更新日期:2018-05-09 00:00:00

  • Ocular abnormalities in a large patient cohort with retinitis pigmentosa in Western China.

    abstract:BACKGROUND:To report the prevalence of ocular abnormalities and investigate visual acuity in a large cohort of retinitis pigmentosa (RP) patients in Western China. METHODS:The medical records and ophthalmic examination reports of 2127 eyes of 1065 RP patients at one eye hospital were retrospectively reviewed to determ...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-020-01797-z

    authors: Tan L,Long Y,Li Z,Ying X,Ren J,Sun C,Meng X,Li S

    更新日期:2021-01-18 00:00:00

  • Reconstruction strategy in isolated complete Cryptophthalmos: a case series.

    abstract:BACKGROUND:The present study sought to introduce clinical characteristics and stepwise surgical strategies of isolated complete cryptophthalmos, a rare, congenital ocular anomaly. CASE PRESENTATION:Retrospective, noncomparative, clinical study. Six patients with isolated complete cryptophthalmos were diagnosed at the ...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-019-1170-6

    authors: Liu Z,Xie B,Li Y,Ding J,Li D

    更新日期:2019-07-31 00:00:00

  • A 8-year retrospective clinical analysis of 272 patients of epidemic Keratoconjunctivitis in Beijing, China.

    abstract:BACKGROUND:Epidemic keratoconjunctivitis (EKC) is one of the most common eye infections worldwide. The analysis of clinical manifestations in different age groups help better know the disease. This study aims to provide more detailed analysis of 272 cases of EKC in 8 years, describe the differences of the clinical feat...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-019-1266-z

    authors: Hou W,Sun X,Feng J,Zhang Y,Wang Z

    更新日期:2019-12-19 00:00:00

  • Comparing the effectiveness and costs of Bevacizumab to Ranibizumab in patients with Diabetic Macular Edema: a randomized clinical trial (the BRDME study).

    abstract:BACKGROUND:The effectiveness of ranibizumab in the treatment of diabetic macular edema has been proven with large clinical trials. For bevacizumab only two clinical trials have been published and a head-to-head comparison is lacking to date. However, if proved non-inferior to ranibizumab, use of the off-label bevacizum...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1186/s12886-015-0043-x

    authors: Schauwvlieghe AM,Dijkman G,Hooymans JM,Verbraak FD,Hoyng CB,Dijkgraaf MG,Van Leeuwen R,Vingerling JR,Moll AC,Schlingemann RO

    更新日期:2015-07-07 00:00:00

  • Extensive bilateral corneal edema 6 weeks after cataract surgery: Keratopathy due to Asclepias physocarpa: a case report.

    abstract:BACKGROUND:Surgeons may be unaware of the ability of plant toxins to cause corneal damage. Therefore, corneal damage following intraocular surgery due to plant toxins may be misdiagnosed as postoperative infection. CASE PRESENTATION:A 74-year-old man presented with hyperemia and reduced visual acuity in both eyes 6 we...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-017-0400-z

    authors: Matsuura K,Hatta S,Terasaka Y,Inoue Y

    更新日期:2017-01-18 00:00:00

  • Amblyopia treatment of adults with dichoptic training using the virtual reality oculus rift head mounted display: preliminary results.

    abstract:BACKGROUND:The gold standard treatments in amblyopia are penalizing therapies, such as patching or blurring vision with atropine that are aimed at forcing the use of the amblyopic eye. However, in the last years, new therapies are being developed and validated, such as dichoptic visual training, aimed at stimulating th...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-017-0501-8

    authors: Žiak P,Holm A,Halička J,Mojžiš P,Piñero DP

    更新日期:2017-06-28 00:00:00

  • Systematic review of the incidence of post-operative trichiasis in Africa.

    abstract:BACKGROUND:Surgery for trichiasis is one of the pillars of the World Health Organization's strategy for global elimination of trachoma as a public health problem. A high incidence of post-operative trichiasis or other poor surgical outcomes could jeopardize these efforts. In this review, we aimed to summarize the repor...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-020-01564-0

    authors: Mwangi G,Courtright P,Solomon AW

    更新日期:2020-11-17 00:00:00

  • Atypical features of nanophthalmic macula--a spectral domain OCT study.

    abstract:BACKGROUND:To report atypical features on Spectral domain optical coherence tomography (SD-OCT) in a case of non-familial pure adult nanophthalmos. CASE PRESENTATION:A 39 year old male hyperope was found to have biometric and fundus findings typical of nanophthalmos. The additional atypical features included serous pi...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/1471-2415-12-12

    authors: Rao A,Padhi TR,Jena S,Mandal S,Das T

    更新日期:2012-06-06 00:00:00

  • Characterization of ex vivo cultured neuronal- and glial- like cells from human idiopathic epiretinal membranes.

    abstract:BACKGROUND:Characterization of the neuro-glial profile of cells growing out of human idiopathic epiretinal membranes (iERMs) and testing their proliferative and pluripotent properties ex vivo is needed to better understand the pathogenesis of their formation. METHODS:iERMs obtained during uneventful vitrectomies were ...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/1471-2415-14-165

    authors: Andjelić S,Lumi X,Yan X,Graw J,Moe MC,Facskó A,Hawlina M,Petrovski G

    更新日期:2014-12-23 00:00:00

  • Predictive multi-imaging biomarkers relevant for visual acuity in idiopathic macular telangiectasis type 1.

    abstract:BACKGROUND:To evaluate the structural changes associated with visual acuity (VA) in patients with idiopathic macular telangiectasia (MT) type 1 using multimodal imaging modalities. METHODS:A retrospective study of 14 patients with MT type 1 and of 10 eyes from 10 healthy individuals as age-matched controls was conduct...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-018-0737-y

    authors: Guo J,Tang W,Ye X,Wu H,Xu G,Liu W,Zhang Y

    更新日期:2018-03-05 00:00:00

  • Recurrent corneal melting in the paraneoplastic pemphigus associated with Castleman's disease.

    abstract:BACKGROUND:The ocular presentation of Castleman's disease (CD)-associated paraneoplastic pemphigus (PNP) has rarely been reported. In this report, we describe a young patient with CD-associated PNP who had recurrent corneal ulceration in addition to cicatrizing conjunctivitis. CASE PRESENTATION:We describe a case of 2...

    journal_title:BMC ophthalmology

    pub_type: 杂志文章

    doi:10.1186/s12886-016-0280-7

    authors: Gong H,Zhou S,Hu Y,Lan Y,Zeng H,Wang L,Liu Q,Wang M

    更新日期:2016-07-12 00:00:00