Abstract：
BACKGROUND:Classification of optical coherence tomography (OCT) images can be achieved with high accuracy using classical convolution neural networks (CNN), a commonly used deep learning network for computer-aided diagnosis. Classical CNN has often been criticized for suppressing positional relations in a pooling layer. Therefore, because capsule networks can learn positional information from images, we attempted application of a capsule network to OCT images to overcome that shortcoming. This study is our attempt to improve classification accuracy by replacing CNN with a capsule network. METHODS:From an OCT dataset, we produced a training dataset of 83,484 images and a test dataset of 1000 images. For training, the dataset comprises 37,205 images with choroidal neovascularization (CNV), 11,348 with diabetic macular edema (DME), 8616 with drusen, and 26,315 normal images. The test dataset has 250 images from each category. The proposed model was constructed based on a capsule network for improving classification accuracy. It was trained using the training dataset. Subsequently, the test dataset was used to evaluate the trained model. RESULTS:Classification of OCT images using our method achieved accuracy of 99.6%, which is 3.2 percentage points higher than that of other methods described in the literature. CONCLUSION:The proposed method achieved classification accuracy results equivalent to those reported for other methods for CNV, DME, drusen, and normal images.
journal_name
BMC Ophthalmoljournal_title
BMC ophthalmologyauthors
Tsuji T,Hirose Y,Fujimori K,Hirose T,Oyama A,Saikawa Y,Mimura T,Shiraishi K,Kobayashi T,Mizota A,Kotoku Jdoi
10.1186/s12886-020-01382-4subject
Has Abstractpub_date
2020-03-19 00:00:00pages
114issue
1issn
1471-2415pii
10.1186/s12886-020-01382-4journal_volume
20pub_type
杂志文章abstract：BACKGROUND:Surgeons may be unaware of the ability of plant toxins to cause corneal damage. Therefore, corneal damage following intraocular surgery due to plant toxins may be misdiagnosed as postoperative infection. CASE PRESENTATION:A 74-year-old man presented with hyperemia and reduced visual acuity in both eyes 6 we...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-017-0400-z
更新日期：2017-01-18 00:00:00
abstract：BACKGROUND:This paper presents and tests a comprehensive computerised system of analysis of digital images of posterior capsule opacification (PCO). It updates and expands significantly on a previous presentation to include facilities for selecting user defined central areas and for registering and subsequent merging o...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-6-30
更新日期：2006-08-23 00:00:00
abstract：BACKGROUND:To evaluate the structural changes associated with visual acuity (VA) in patients with idiopathic macular telangiectasia (MT) type 1 using multimodal imaging modalities. METHODS:A retrospective study of 14 patients with MT type 1 and of 10 eyes from 10 healthy individuals as age-matched controls was conduct...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0737-y
更新日期：2018-03-05 00:00:00
abstract：BACKGROUND:The tear film breakup time (tBUT) is a clinical evaluation of evaporative dry eye disease assessed by instilling topical fluorescein into the eyes. In the present study, we introduce a new diagnostic test, blinking tolerance time (BTT), for self-evaluation of tear-film stability. We compared the results with...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01686-5
更新日期：2020-11-04 00:00:00
abstract：BACKGROUND:Retinal detachment is a disorder of the eye in which sensory retina separates from the retinal pigment epithelium (RPE) due to accumulation of fluid in subretinal space. Pharmacological stimulation of fluid reabsorption from subretinal space to choroid across the RPE has been suggested as a treatment strateg...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-11-33
更新日期：2011-11-15 00:00:00
abstract：BACKGROUND:This multicentre, retro-prospective real-world study evaluated the visual, refractive and safety outcomes of a monofocal lens 1 year after implantation in cataract patients with or without pre-existing ocular pathologies. METHODS:Records from 4 centres in Germany and Sweden were reviewed to select eyes with...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01493-y
更新日期：2020-06-11 00:00:00
abstract：BACKGROUND:Raised intraocular pressure (IOP) is the only causal risk factor for glaucoma that can be therapeutically manipulated to change the course of the disease process. Though Goldman applanation tonometry (GAT) is the "gold standard" for IOP measurement, readings of IOP with GAT are affected by central corneal th...
journal_title：BMC ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1186/1471-2415-12-58
更新日期：2012-11-27 00:00:00
abstract：BACKGROUND:To determine the accuracy of the T2 formula as applied to highly myopic eyes, to compare the T2 formula to the SRK/T and Holladay 1 formulas, and to describe possible ways to improve the estimation of corneal height and prediction error in two settings, the Hadassah Hospital, Ophthalmology Department, Jerusa...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-019-1226-7
更新日期：2019-11-12 00:00:00
abstract：:Conjunctival and subconjunctival fibrogenesis and inflammation are sight compromising side effects that can occur subsequent to glaucoma filtration surgery. Despite initial declines in intraocular pressure resulting from increasing aqueous outflow, one of the activated responses includes marshalling of proinflammatory...
journal_title：BMC ophthalmology
pub_type： 杂志文章,评审
doi：10.1186/s12886-015-0134-8
更新日期：2015-12-17 00:00:00
abstract：BACKGROUND:The purpose of this study was to identify the genetic cause and describe the clinical phenotype of Schnyder corneal dystrophy (SCD) in six unrelated probands. METHODS:We identified two white Czech, two white British and two South Asian families with a clinical diagnosis of SCD. Ophthalmic assessment include...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0918-8
更新日期：2018-09-17 00:00:00
abstract：BACKGROUND:A 23 year old white male with a history of social and behavioural problems attempted to blind himself chemically, with alcohol, and mechanically, with a razor blade. METHODS:Observational case report of a patient who self-inflicted bilateral scleral lacerations with a razor blade, after losing his job. RES...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-9-14
更新日期：2009-12-10 00:00:00
abstract：:Ophthalmologists and researchers in ophthalmology understand what a rapidly evolving field ophthalmology is, and that to conduct good research it is essential to use the latest and best methods. In outcomes research, one modern initiative has been to conduct holistic measurement of outcomes inclusive of the patient's ...
journal_title：BMC ophthalmology
pub_type： 社论,评审
doi：10.1186/1471-2415-6-25
更新日期：2006-06-15 00:00:00
abstract：BACKGROUND:Retinal dystrophies display a considerably wide range of phenotypic variability, which can make diagnosis and clinical staging difficult. The aim of the study is to analyze the contribution of retro-mode imaging (RMI) and fundus autofluorescence (FAF) to the characterization of retinal dystrophies. METHODS:...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-12-8
更新日期：2012-05-15 00:00:00
abstract：BACKGROUND:To evaluate the effects of anterior capsular opening size on deviation from predicted refraction and the effective position of the intraocular lens (ELP) in cataract surgery. METHODS:Nonrandomized clinical trial. Eighty patients (80 eyes) with simple age-related cataracts were treated from May 2018 to Septe...
journal_title：BMC ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1186/s12886-019-1068-3
更新日期：2019-02-21 00:00:00
abstract：BACKGROUND:The ocular presentation of Castleman's disease (CD)-associated paraneoplastic pemphigus (PNP) has rarely been reported. In this report, we describe a young patient with CD-associated PNP who had recurrent corneal ulceration in addition to cicatrizing conjunctivitis. CASE PRESENTATION:We describe a case of 2...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-016-0280-7
更新日期：2016-07-12 00:00:00
abstract：BACKGROUND:Older drivers aged ≥70 years old have among the highest rates of motor vehicle collisions (MVC) compared to other age groups. Driving is a highly visual task, and older adults have a high prevalence of vision impairment compared to other ages. Most studies addressing visual risk factors for MVCs by older dri...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0686-5
更新日期：2018-02-07 00:00:00
abstract：BACKGROUND:An increase in macular thickness due to fluid accumulation in the macula in patients with diabetes mellitus. Optical coherence tomography (OCT) has been shown to be highly reproducible in measuring macular thickness in normal individuals and diabetic patients. OCT can detect subtle changes of macular thickne...
journal_title：BMC ophthalmology
pub_type： 杂志文章,收录出版
doi：10.1186/1471-2415-13-11
更新日期：2013-04-09 00:00:00
abstract：BACKGROUND:The ability to image wide fundus fields and to conduct swift, non-invasive examinations is increasingly important with the escalation in patients with diabetic retinopathy (DR). METHODS:Fifty eyes of 28 consecutive patients with DR were examined in this prospective observational study. A total of 46 eyes, 2...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-1011-z
更新日期：2018-12-20 00:00:00
abstract：BACKGROUND:The aim of this study was to determine the interocular differences in the peripapillary retinal nerve fibre layer (RNFL), peripapillary choroidal thickness (PCT) and subfoveal choroidal thickness (SFCT) in healthy adults with isometropia, using enhanced depth imaging optical coherence tomography (EDI SD-OCT)...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-016-0361-7
更新日期：2016-10-19 00:00:00
abstract：BACKGROUND:This objective of the review and analysis is to demonstrate that acyclovir (ACV) 3% ophthalmic ointment is superior to idoxuridine (IDU) in treating herpetic keratitis (HK) presenting as dendritic and geographic ulcer sub-types. METHODS: DATA SOURCES:Publications in human subjects were identified by search...
journal_title：BMC ophthalmology
pub_type： 杂志文章,meta分析,评审
doi：10.1186/s12886-015-0022-2
更新日期：2015-04-17 00:00:00
abstract：BACKGROUND:Proliferative retinopathy is an uncommon feature of Vogt Koyanagi Harada (VKH) disease which might indicate poor uveitis control in these patients. We aim to describe the clinical features and outcome of management of proliferative retinopathy in 2 patients with VKH. CASE PRESENTATION:19 and 33 years old fe...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01736-y
更新日期：2020-12-01 00:00:00
abstract：BACKGROUND:To report patients with age-related macular degeneration and atypical central retinal pigment epithelium (RPE) defects not attributable to geographic atrophy (GA) or RPE-tears with overlying preserved photoreceptor layers. METHODS:Multimodal imaging case-series evaluating the course of atypical RPE- defects...
journal_title：BMC ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1186/s12886-017-0452-0
更新日期：2017-05-15 00:00:00
abstract：BACKGROUND:we conducted our meta-analysis of published studies to assess existing evidence about the efficacy and safety of vitrectomy with ILM peeling vs. that of vitrectomy with no ILM peeling for Macular hole-induced retinal detachment. METHODS:Databases, including Pubmed, Cochrane Library, Ovid, Web of Science, Wa...
journal_title：BMC ophthalmology
pub_type： 杂志文章,meta分析
doi：10.1186/s12886-015-0048-5
更新日期：2015-06-20 00:00:00
abstract：BACKGROUND:The primary aim was to estimate the incidence of primary and secondary childhood glaucoma in Scotland over a 2-year period. The secondary aim was to gauge the confidence and experience of ophthalmologists in Scotland in managing these patients. METHODS:A 7 question electronic survey was distributed to all c...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01347-7
更新日期：2020-02-27 00:00:00
abstract：BACKGROUND:To analyze the clinical characteristics, treatment and prognosis of children with unilateral retinoblastoma (RB) and intracranial segment of retrobulbar optic nerve invasion. METHODS:A total of 14 children with unilateral RB and intracranial segment of retrobulbar optic nerve invasion were enrolled in this ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-020-01768-4
更新日期：2021-01-14 00:00:00
abstract：BACKGROUND:To describe the superiority of ocular ultrasound in the diagnostic management of extrascleral extension in choroidal melanoma. CASE PRESENTATION:We present a case of a 94-year-old male with choroidal melanoma of the right eye imaged with MRI and ocular ultrasound to aid in the detection of extrascleral exte...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/s12886-018-0990-0
更新日期：2018-12-12 00:00:00
abstract：BACKGROUND:Retinal artery occlusion caused by myxoma is relatively rare. There are several points that should be taken into consideration to avoid overlooking this disorder. CASE PRESENTATION:This case report describes a 43-year-old woman with sudden vision loss in her left eye for 20 days after single sudden syncope....
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-14-164
更新日期：2014-12-23 00:00:00
abstract：BACKGROUND:This case report describes a patient with chronic unilateral chemosis, likely due to treatment with amlodipine besylate. CASE PRESENTATION:A 52-year-old man visited the clinic with symptoms of foreign body sensation and puffiness in his right eye, which had persisted for 4 months. There were no other sympto...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-14-124
更新日期：2014-10-21 00:00:00
abstract：BACKGROUND:With age, the human lens accumulates variety of substances that absorbs and fluorescence, which explains the color of yellow, brunescent and nigrescent cataract in terms of aging. The aim of this study was to assess lens fluorophores with properties comparable to those of advanced glycated end products (AGEs...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-6-10
更新日期：2006-03-06 00:00:00
abstract：BACKGROUND:Blank cartridge guns are generally regarded as being harmless and relative safe. However recent published articles demonstrated that the gas pressure from the exploding propellant of blank cartridge is powerful enough to penetrate the thoracic wall, abdominal muscle, small intestine and the skull. And there ...
journal_title：BMC ophthalmology
pub_type： 杂志文章
doi：10.1186/1471-2415-14-23
更新日期：2014-03-03 00:00:00
