Proliferative retinopathy as a feature of Vogt Koyanagi Harada Disease: a report of two cases.

Abstract:

BACKGROUND:Proliferative retinopathy is an uncommon feature of Vogt Koyanagi Harada (VKH) disease which might indicate poor uveitis control in these patients. We aim to describe the clinical features and outcome of management of proliferative retinopathy in 2 patients with VKH. CASE PRESENTATION:19 and 33 years old females with VKH presented with unilateral proliferative retinopathy. Both patients had neovascularization of the optic disc (NVDs) and one patient had neovascularizations elsewhere (NVEs) and preretinal hemorrhage. Both patients had exudative retinal detachments (ERD). Systemic steroids and immunomodulatory agents were successfully used to control inflammation and achieve regression. One patient developed fibrous tissue formation at the disc area as well as an epiretinal membrane formation, for which she had pars plana vitrectomy with membrane peeling. Both patients had controlled inflammation with stable vision. CONCLUSIONS:Proliferative retinopathy can present variably in VKH patients and indicates persistent inflammation which is incompletely controlled. Proper uveitis control is sufficient to achieve regression of retinal neovascularization.

journal_name

BMC Ophthalmol

journal_title

BMC ophthalmology

authors

Magliyah MS,Al-Fakhri AS,Al-Dhibi HA

doi

10.1186/s12886-020-01736-y

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

470

issue

1

issn

1471-2415

pii

10.1186/s12886-020-01736-y

journal_volume

20

pub_type

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