Abstract:
:Endurance exercise training can increase intestinal permeability which may contribute to the development of gastrointestinal symptoms in some athletes. Bovine colostrum (BC) supplementation reduces intestinal permeability induced by non-steroidal anti-inflammatory drugs. This study aimed to determine whether BC could also reduce intestinal permeability induced by endurance exercise. Thirty healthy adult males (25.0 ± 4.7 yr; mean ± SD) completed eight weeks of running three times per week for 45 minutes at their lactate threshold while consuming 60 g/day of BC, whey protein (WP) or control (CON). Intestinal permeability was assessed at baseline and after eight weeks by measuring the ratio of urinary lactulose (L) and rhamnose (R) excretion. After eight weeks the L/R ratio increased significantly more in volunteers consuming BC (251 ± 140%) compared with WP (21 ± 35%, P < 0.05) and CON (-7 ± 13%, P < 0.02). The increase in intestinal permeability with BC may have been due to BC inducing greater leakiness of tight junctions between enterocytes or by increasing macromolecular transport as it does in neonatal gut. Further research should investigate the potential for BC to increase intestinal macromolecular transport in adults.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Buckley JD,Butler RN,Southcott E,Brinkworth GDdoi
10.3390/nu1020224subject
Has Abstractpub_date
2009-02-01 00:00:00pages
224-34issue
2issn
2072-6643pii
nu1020224journal_volume
1pub_type
杂志文章,随机对照试验相关文献
Nutrients文献大全abstract::Anthracycline anticancer drugs, such as doxorubicin (DOX), can induce cardiotoxicity supposed to be related to mitochondrial damage. We have recently demonstrated that a branched-chain amino acid (BCAA)-enriched mixture (BCAAem), supplemented with drinking water to middle-aged mice, was able to promote mitochondrial b...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12020282
更新日期:2020-01-21 00:00:00
abstract::This study aimed to compare calculated nutrient intakes from two different food composition databases using data from the European prospective investigation into cancer and nutrition (EPIC) cohort. Dietary intake data of the EPIC cohort was recently matched to 150 food components from the U.S. nutrient database (USNDB...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12102906
更新日期:2020-09-23 00:00:00
abstract::Hyperhomocysteinemia (HHcy) is a risk factor for atherosclerosis through mechanisms which are still incompletely defined. One possible mechanism involves the hypomethylation of the nuclear histone proteins to favor the progression of atherosclerosis. In previous cell studies, hypomethylating stress decreased a specifi...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12082182
更新日期:2020-07-23 00:00:00
abstract::The enzyme transglutaminase 2 (TG2) plays a crucial role in the initiation of celiac disease by catalyzing the deamidation of gluten peptides. In susceptible individuals, the deamidated peptides initiate an immune response leading to celiac disease. Several studies have addressed lactic fermentation plus addition of e...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu7042134
更新日期:2015-03-25 00:00:00
abstract::Effects of meal frequency on blood glucose levels and glucose metabolism were evaluated over 3 days in adult males with normal glucose tolerance (NGT, n = 9) or impaired fasting glucose (IFG, n = 9) in a randomized, crossover comparison study. Subjects were provided with an isocaloric diet 3 times daily (3M) or 9 time...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11092126
更新日期:2019-09-06 00:00:00
abstract::Ongoing dietary transitions in the Solomon Islands has resulted in an over-reliance on commercially sourced foods, leading to food insecurity, and a subsequent rise in multiple forms of malnutrition. The aim of this study was to investigate the individual dietary diversity and food preferences of the adult population ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11071622
更新日期:2019-07-17 00:00:00
abstract::Polygonatum sibiricum (PS) rhizome, which contains glyceryl-1-monolinoleate as its primary active component, has been shown to improve insomnia in animal models. Based on these findings, we aimed to investigate the safety and efficacy of PS rhizome extract in improving sleep quality in individuals with mild insomnia. ...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11081719
更新日期:2019-07-25 00:00:00
abstract::Athletes competing in ultra-endurance sports should manage nutritional issues, especially with regards to energy and fluid balance. An ultra-endurance race, considered a duration of at least 6 h, might induce the energy balance (i.e., energy deficit) in levels that could reach up to ~7000 kcal per day. Such a negative...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu10121995
更新日期:2018-12-16 00:00:00
abstract::Efforts to shape the food environment are aimed at reducing diet-related co-morbidities. Front-of-package labeling (FOPL) may support the consumers to make an informed decision at the point of purchase and encourage industry to reformulate food products. The Israeli Ministry of Health (MOH) implemented a unique FOPL s...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12061875
更新日期:2020-06-23 00:00:00
abstract::Celiac disease (CD) is a chronic immune-mediated disorder, characterized by enhanced paracellular permeability across the intestinal epithelium. The complex system of intercellular junctions, including tight junctions (TJs) and adherens junctions (AJs), seals together the epithelial cells to form a continuous layer. T...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10111698
更新日期:2018-11-07 00:00:00
abstract::Long-chain (LC) omega-3 PUFA derived from marine sources may play an important role in cognitive performance throughout all life stages. Docosahexaenoic acid (DHA), the dominant omega-3 in the brain, is a major component of neuronal cell membranes and affects various neurological pathways and processess. Despite its c...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu6072730
更新日期:2014-07-22 00:00:00
abstract::Chicken extract, which is rich in anserine and carnosine, has been widely taken in Asian countries as a traditional remedy with various aims, including attenuation of psychological fatigue. The effects of consuming BRAND'S Essence of Chicken (EOC) or a placebo on 46 young adults' responses to a standard psychological ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu7020887
更新日期:2015-01-29 00:00:00
abstract::Calcium is the main mineral in the body [...]. ...
journal_title:Nutrients
pub_type: 社论
doi:10.3390/nu12020416
更新日期:2020-02-06 00:00:00
abstract::Previous psychological studies have shown that images of food elicit hedonic responses, either consciously or unconsciously, and that participants' cultural experiences moderate conscious hedonic ratings of food. However, whether cultural factors moderate unconscious hedonic responses to food remains unknown. We inves...
journal_title:Nutrients
pub_type: 杂志文章,多中心研究
doi:10.3390/nu11112832
更新日期:2019-11-19 00:00:00
abstract::The current performance indicator for universal salt iodisation (USI) is the percentage of households using adequately iodised salt. However, the proportion of dietary salt from household salt is decreasing with the increase in consumption of processed foods and condiments globally. This paper reports on case studies ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9080797
更新日期:2017-07-26 00:00:00
abstract::Hand osteoarthritis (OA) is a degenerative joint disease which leads to pain and disability. Recent studies focus on the role of obesity and metabolic syndrome in inducing or worsening joint damage in hand OA patients, suggesting that chronic low-grade systemic inflammation may represent a possible linking factor. The...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12113469
更新日期:2020-11-12 00:00:00
abstract::Stimulation of the ubiquitin-proteasome pathway-especially E3 ubiquitin ligases Atrogin-1 and MuRF1-is associated with muscle loss in diabetes. Elevated lipid metabolites impair myogenesis. Oligonol, a low molecular weight polyphenol derived from lychee, exhibited anti-diabetic and anti-obesity properties, suggesting ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9091040
更新日期:2017-09-20 00:00:00
abstract::Iron is an essential micronutrient that is involved in many functions in humans, as it plays a critical role in the growth and development of the central nervous system, among others. Premature and low birth weight infants have higher iron requirements due to increased postnatal growth compared to that of term infants...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11051090
更新日期:2019-05-16 00:00:00
abstract::Fermented foods represent a significant fraction of human diets. Although their impact on health is positively perceived, an objective evaluation is still missing. We have, therefore, reviewed meta-analyses of randomized controlled trials (RCT) investigating the relationship between fermented foods and non-transmissib...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu10040448
更新日期:2018-04-04 00:00:00
abstract::Many Americans are attempting to lose weight with the help of healthcare professionals. Clinicians can improve weight loss results by using technology. Accurate dietary assessment is crucial to effective weight loss. The aim of this study was to validate a computer-led dietary assessment method in overweight/obese wom...
journal_title:Nutrients
pub_type: 临床试验,杂志文章
doi:10.3390/nu9030218
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Oral supplementation of anserine/carnosine helps preserve cognitive functions in healthy older adults. Mild cognitive impairment (MCI) is a transition between cognitive-normal and dementia. Therefore, it needs to investigate whether anserine/carnosine supplementation (ACS) has effects on subjects with MCI. ...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11071626
更新日期:2019-07-17 00:00:00
abstract::Susceptibility to develop hypertension may be established during early stages of life that include the intrauterine period, infancy and childhood. We recently showed that blood pressure increased when rats reached adulthood when sucrose was ingested for a short-term critical window from postnatal day 12 to 28 in the r...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11020309
更新日期:2019-02-01 00:00:00
abstract::In this study, we investigated the beneficial effects of milk biofortified with antioxidants on the health of children. Two experiments were conducted: experiment one evaluated the milk of 24 Jersey dairy cows (450 ± 25 kg of body weight (BW); 60 ± 30 days in milk dry matter intake (DIM)) given different diet treatmen...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11061218
更新日期:2019-05-29 00:00:00
abstract::Trimethylamine-N-oxide (TMAO) is a small organic molecule, derived from the intestinal and hepatic metabolism of dietary choline and carnitine. Although the involvement of TMAO in the framework of many chronic diseases has been recently described, no evidence on its putative role in the central nervous system has been...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9101053
更新日期:2017-09-22 00:00:00
abstract::Early meal timing and chronotype are associated with lower BMI, but their impact on appetite is poorly understood. We examined the impact of meal timing and chronotype on appetite and food reward. Forty-four adults were divided into early (EC; Morningness-Eveningness Questionnaire (MEQ) score = 55 ± 5) or late chronot...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12051506
更新日期:2020-05-22 00:00:00
abstract::The objective of this cross-sectional study was to evaluate the relationship between micronutrient status and obesity, lipids, insulin resistance and chronic inflammation in children. Weight, height, waist circumference and body composition (dual-energy X-ray absorptiometry (DEXA)) were determined in 197 school-aged c...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu5125012
更新日期:2013-12-10 00:00:00
abstract:BACKGROUND:The C57BL/6 mouse fed a high fat diet is a common and valuable model in experimental studies of obesity and type 2 diabetes (T2D). Different high fat diets are used and in order to determine which diet produces a model most accurately resembling human T2D, they need to be compared head-to-head. METHODS:Four...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu4101367
更新日期:2012-09-28 00:00:00
abstract::A growing literature is dedicated to the understanding of carotenoid beneficial health effects. However, the absorption process of this broad family of molecules is still poorly understood. These highly lipophilic plant metabolites are usually weakly absorbed. It was long believed that β-carotene absorption (the princ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11040838
更新日期:2019-04-13 00:00:00
abstract::Dietary polyphenols are multi-target compounds that have been considered promising candidates in strategies for the mitigation of neurological diseases, acting particularly through reduction of microglia-driven neuroinflammation. In this study, an anthocyanin-rich extract obtained from Portuguese blueberries was subje...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12123670
更新日期:2020-11-28 00:00:00
abstract::Anthropometry (from the Greek anthropos: human, and metron: measure) refers to the systematic collection and correlation of measurements of human individuals, including the systematic measurement of the physical characteristics of the human body, primarily body weight, body size, and shape [...]. ...
journal_title:Nutrients
pub_type: 社论
doi:10.3390/nu11081891
更新日期:2019-08-14 00:00:00