当前位置： SCI文献检索 > Nutrients期刊下所有文献 > Effect of Short-Term Increase in Meal Frequency on Glucose Metabolism in Individuals with Normal Glucose Tolerance or Impaired Fasting Glucose: A Randomized Crossover Clinical Trial.

Effect of Short-Term Increase in Meal Frequency on Glucose Metabolism in Individuals with Normal Glucose Tolerance or Impaired Fasting Glucose: A Randomized Crossover Clinical Trial.

Abstract：

:Effects of meal frequency on blood glucose levels and glucose metabolism were evaluated over 3 days in adult males with normal glucose tolerance (NGT, n = 9) or impaired fasting glucose (IFG, n = 9) in a randomized, crossover comparison study. Subjects were provided with an isocaloric diet 3 times daily (3M) or 9 times daily (9M). Blood glucose was monitored on Day 3 using a continuous glucose monitoring system, and subjects underwent a 75-g oral glucose tolerance test (OGTT) on Day 4. Daytime maximum blood glucose, glucose range, duration of glucose ≥180 mg/dL, and nighttime maximum glucose were significantly lower in the NGT/9M condition than in the NGT/3M condition. Similar findings were observed in the IFG subjects, with a lower daytime and nighttime maximum glucose and glucose range, and a significantly higher daytime minimum glucose in the 9M condition than in the 3M condition. The OGTT results did not differ significantly between NGT/3M and NGT/9M conditions. In contrast, the incremental area under the curve tended to be lower and the maximum plasma glucose concentration was significantly lower in the IFG/9M condition than in the IFG/3M condition. In IFG subjects, the 9M condition significantly improved glucose metabolism compared with the 3M condition. Higher meal frequency may increase glucagon-like peptide 1 secretion and improve insulin secretion.

journal_name

Nutrients

journal_title

Nutrients

authors

Hibi M,Hari S,Yamaguchi T,Mitsui Y,Kondo S,Katashima M

doi

10.3390/nu11092126

subject

Has Abstract

pub_date

2019-09-06 00:00:00

issue

9

issn

2072-6643

pii

nu11092126

journal_volume

11

pub_type

杂志文章,随机对照试验

相关文献

Nutrients文献大全
  • The Usefulness of Anthropometric Indices to Identify the Risk of Metabolic Syndrome.

    abstract：:Despite several papers having been published on the association between adiposity and the risk of metabolic syndrome (MetS), it is still difficult to determine unambiguously which of the indices of nutritional status is the best to identify MetS. The aim of this study was to analyze the ability of six anthropometric i...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu11112598

    authors： Suliga E,Ciesla E,Głuszek-Osuch M,Rogula T,Głuszek S,Kozieł D

    更新日期：2019-10-29 00:00:00

  • Does vitamin C deficiency affect cognitive development and function?

    abstract：:Vitamin C is a pivotal antioxidant in the brain and has been reported to have numerous functions, including reactive oxygen species scavenging, neuromodulation, and involvement in angiogenesis. Absence of vitamin C in the brain has been shown to be detrimental to survival in newborn SVCT2(-/-) mice and perinatal defic...

    journal_title：Nutrients

    pub_type： 杂志文章,评审

    doi：10.3390/nu6093818

    authors： Hansen SN,Tveden-Nyborg P,Lykkesfeldt J

    更新日期：2014-09-19 00:00:00

  • Cyanidin Stimulates Insulin Secretion and Pancreatic β-Cell Gene Expression through Activation of l-type Voltage-Dependent Ca2+ Channels.

    abstract：:Cyanidin is a natural anthocyanidin present in fruits and vegetables with anti-diabetic properties including stimulation of insulin secretion. However, its mechanism of action remains unknown. In this study, we elucidated the mechanisms of cyanidin for stimulatory insulin secretion from pancreatic β-cells. Rat pancrea...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu9080814

    authors： Suantawee T,Elazab ST,Hsu WH,Yao S,Cheng H,Adisakwattana S

    更新日期：2017-07-28 00:00:00

  • Micronutrient Status of Recreational Runners with Vegetarian or Non-Vegetarian Dietary Patterns.

    abstract：:Vegetarian diets have gained popularity in sports. However, few data exist on the status of micronutrients and related biomarkers for vegetarian and vegan athletes. The aim of this cross-sectional study was to compare the micronutrient status of omnivorous (OMN, n = 27), lacto-ovo-vegetarian (LOV, n = 26), and vegan (...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu11051146

    authors： Nebl J,Schuchardt JP,Ströhle A,Wasserfurth P,Haufe S,Eigendorf J,Tegtbur U,Hahn A

    更新日期：2019-05-22 00:00:00

  • Gut Microbiota Modulation by Dietary Barley Malt Melanoidins.

    abstract：:Melanoidins are the final Maillard reaction products (protein-carbohydrate complexes) produced in food by prolonged and intense heating. We assessed the impact of the consumption of melanoidins from barley malts on gut microbiota. Seventy-five mice were assigned into five groups, where the control group consumed a non...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu12010241

    authors： Aljahdali N,Gadonna-Widehem P,Anton PM,Carbonero F

    更新日期：2020-01-17 00:00:00

  • Diet Quality and Nutrient Intake of Urban Overweight and Obese Primarily African American Older Adults with Osteoarthritis.

    abstract：:Diet quality may be a unique target for preventing and managing obesity-related osteoarthritis (OA). Using the Healthy Eating Index-2010 (HEI-2010), this study examined the nutrient intake and diet quality of 400 urban overweight and obese primarily African American older adults with self-reported lower extremity OA. ...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu10040485

    authors： Vergis S,Schiffer L,White T,McLeod A,Khudeira N,Demott A,Fitzgibbon M,Hughes S,Tussing-Humphreys L

    更新日期：2018-04-13 00:00:00

  • Study on the Prevalence of Severe Anemia among Non-Pregnant Women of Reproductive Age in Rural China: A Large Population-Based Cross-Sectional Study.

    abstract：:Globally, severe anemia impacts millions of non-pregnant women. However, studies on the prevalence of severe anemia through large epidemiologic surveys among non-pregnant women have been scarce in China. In this study, we aimed to study the prevalence of severe anemia and its determinants among non-pregnant women livi...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu9121298

    authors： Ma Q,Zhang S,Liu J,Wang Q,Shen H,Zhang Y,Liu M

    更新日期：2017-11-28 00:00:00

  • Parents' Perception of Food Insecurity and of Its Effects on Their Children in Italy Six Months after the COVID-19 Pandemic Outbreak.

    abstract：:The Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) pandemic and subsequent containment measures are causing an increase in food insecurity (FI) worldwide, with direct consequences on children's nutrition. We aimed to investigate the effects of the lockdown imposed in Italy on FI and changes in eating hab...

    journal_title：Nutrients

    pub_type： 临床试验,杂志文章

    doi：10.3390/nu13010121

    authors： Dondi A,Candela E,Morigi F,Lenzi J,Pierantoni L,Lanari M

    更新日期：2020-12-31 00:00:00

  • Impact of Coffee, Wine, and Chocolate Consumption on Cognitive Outcome and MRI Parameters in Old Age.

    abstract：:Coffee, wine and chocolate are three frequently consumed substances with a significant impact on cognition. In order to define the structural and cerebral blood flow correlates of self-reported consumption of coffee, wine and chocolate in old age, we assessed cognition and brain MRI measures in 145 community-based eld...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu10101391

    authors： Haller S,Montandon ML,Rodriguez C,Herrmann FR,Giannakopoulos P

    更新日期：2018-10-01 00:00:00

  • Potential of phytase-mediated iron release from cereal-based foods: a quantitative view.

    abstract：:The major part of iron present in plant foods such as cereals is largely unavailable for direct absorption in humans due to complexation with the negatively charged phosphate groups of phytate (myo-inositol (1,2,3,4,5,6)-hexakisphosphate). Human biology has not evolved an efficient mechanism to naturally release iron ...

    journal_title：Nutrients

    pub_type： 杂志文章,评审

    doi：10.3390/nu5083074

    authors： Nielsen AV,Tetens I,Meyer AS

    更新日期：2013-08-02 00:00:00

  • Esophageal, Gastric, and Duodenal Histologic Findings in Patients with Feeding Difficulties.

    abstract：:Currently, there are inconsistencies in the recommendations of when to obtain an esophagogastroduodenoscopy (EGD) in children with feeding difficulties. The aim of our study was to identify EGD findings in patients presenting to a large, outpatient feeding program. Additionally, we investigated the presence of any rel...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu12092822

    authors： Edwards J,Friesen C,Issa A,Edwards S

    更新日期：2020-09-15 00:00:00

  • Serum Amyloid A Production Is Triggered by Sleep Deprivation in Mice and Humans: Is That the Link between Sleep Loss and Associated Comorbidities?

    abstract：:Serum amyloid A (SAA) was recently associated with metabolic endotoxemia, obesity and insulin resistance. Concurrently, insufficient sleep adversely affects metabolic health and is an independent predisposing factor for obesity and insulin resistance. In this study we investigated whether sleep loss modulates SAA prod...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu9030311

    authors： de Oliveira EM,Visniauskas B,Tufik S,Andersen ML,Chagas JR,Campa A

    更新日期：2017-03-21 00:00:00

  • Fructose Consumption by Adult Rats Exposed to Dexamethasone In Utero Changes the Phenotype of Intestinal Epithelial Cells and Exacerbates Intestinal Gluconeogenesis.

    abstract：:Fructose consumption by rodents modulates both hepatic and intestinal lipid metabolism and gluconeogenesis. We have previously demonstrated that in utero exposure to dexamethasone (DEX) interacts with fructose consumption during adult life to exacerbate hepatic steatosis in rats. The aim of this study was to clarify i...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu12103062

    authors： Pereira GA,Sodré FS,Murata GM,Amaral AG,Payolla TB,Campos CV,Sato FT,Anhê GF,Bordin S

    更新日期：2020-10-07 00:00:00

  • DHA in Pregnant and Lactating Women from Coastland, Lakeland, and Inland Areas of China: Results of a DHA Evaluation in Women (DEW) Study.

    abstract：:Few studies have examined docosahexaenoic acid (DHA) in pregnant and lactating women in developing countries like China, where DHA-enriched supplements are increasingly popular. We aimed to assess the DHA status among Chinese pregnant and lactating women residing areas differing in the availability of aquatic products...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu7105428

    authors： Li Y,Li HT,Trasande L,Ge H,Yu LX,Xu GS,Bai MX,Liu JM

    更新日期：2015-10-21 00:00:00

  • Vitamin B6, Inflammation, and Cardiovascular Outcome in a Population-Based Cohort: The Prevention of Renal and Vascular End-Stage Disease (PREVEND) Study.

    abstract：BACKGROUND:a large number of studies have linked vitamin B6 to inflammation and cardiovascular disease in the general population. However, it remains uncertain whether vitamin B6 is associated with cardiovascular outcome independent of inflammation. METHODS:we measured plasma pyridoxal 5'-phosphate (PLP), as an indica...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu12092711

    authors： Minović I,Kieneker LM,Gansevoort RT,Eggersdorfer M,Touw DJ,Voerman AJ,Connelly MA,Boer RA,Hak E,Bos J,Dullaart RPF,Kema IP,Bakker SJL

    更新日期：2020-09-04 00:00:00

  • Selected vitamins and essential elements in meat from semi-domesticated reindeer (Rangifer tarandus tarandus L.) in mid- and northern Norway: geographical variations and effect of animal population density.

    abstract：:Meat samples (n = 100) were collected from semi-domesticated reindeer originating from 10 grazing districts in Norway. We aimed at studying concentrations, correlations, geographical variations and the effect of animal population density on vitamins A, B3, B7, B12 and E, and calcium, iron, zinc, selenium, chromium and...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu4070724

    authors： Hassan AA,Sandanger TM,Brustad M

    更新日期：2012-07-01 00:00:00

  • The Association between Seafood Intake and Fecundability: Analysis from Two Prospective Studies.

    abstract：BACKGROUND:Seafood is an important source of omega-3 fatty acids, which have been associated with improved oocyte quality and embryo morphology in some studies. However, seafood is also a source of persistent organic pollutants and heavy metals, which may adversely affect fecundity. Previous studies of seafood intake a...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu12082276

    authors： Wise LA,Willis SK,Mikkelsen EM,Wesselink AK,Sørensen HT,Rothman KJ,Tucker KL,Trolle E,Vinceti M,Hatch EE

    更新日期：2020-07-29 00:00:00

  • Association between polymorphisms in the fatty acid desaturase gene cluster and the plasma triacylglycerol response to an n-3 PUFA supplementation.

    abstract：:Eicosapentaenoic and docosahexaenoic acids have been reported to have a variety of beneficial effects on cardiovascular disease risk factors. However, a large inter-individual variability in the plasma lipid response to an omega-3 (n-3) polyunsaturated fatty acid (PUFA) supplementation is observed in different studies...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu4081026

    authors： Cormier H,Rudkowska I,Paradis AM,Thifault E,Garneau V,Lemieux S,Couture P,Vohl MC

    更新日期：2012-08-01 00:00:00

  • The Role of Succinate in the Regulation of Intestinal Inflammation.

    abstract：:Succinate is a metabolic intermediate of the tricarboxylic acid (TCA) cycle within host cells. Succinate is also produced in large amounts during bacterial fermentation of dietary fiber. Elevated succinate levels within the gut lumen have been reported in association with microbiome disturbances (dysbiosis), as well a...

    journal_title：Nutrients

    pub_type： 杂志文章,评审

    doi：10.3390/nu11010025

    authors： Connors J,Dawe N,Van Limbergen J

    更新日期：2018-12-22 00:00:00

  • Sodium and Potassium Intake and Cardiovascular Disease in Older People: A Systematic Review.

    abstract：:This review aims to examine the relationship of sodium and potassium intake and cardiovascular disease (CVD) among older people. METHODS:We performed a literature search using PubMed and Web of Science (January 2015 to July 2020) without language restriction. Observational and experimental studies that reported the r...

    journal_title：Nutrients

    pub_type： 杂志文章,评审

    doi：10.3390/nu12113447

    authors： Gonçalves C,Abreu S

    更新日期：2020-11-10 00:00:00

  • Exploration of the Association between Dietary Fiber Intake and Hypertension among U.S. Adults Using 2017 American College of Cardiology/American Heart Association Blood Pressure Guidelines: NHANES 2007⁻2014.

    abstract：:This study aimed to explore the association between dietary fiber intake and hypertension risk using 2017 American College of Cardiology/American Heart Association Blood Pressure Guidelines. Data from the National Health and Nutrition Examination Survey 2007⁻2014 were used in this study. Dietary fiber data were obtain...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu10081091

    authors： Sun B,Shi X,Wang T,Zhang D

    更新日期：2018-08-15 00:00:00

  • Variation in the TAS2R38 Bitterness Receptor Gene Was Associated with Food Consumption and Obesity Risk in Koreans.

    abstract：:Bitterness-sensing protein taste receptor type-2 member 38 (TAS2R38, T2R38) mediates taste perception and various physiological responses, including energy- and adiposity-related mechanisms. This study examined whether the genetic variant rs10246939 C > T in TAS2R38 was associated with food intake and body size as wel...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu11091973

    authors： Choi JH

    更新日期：2019-08-21 00:00:00

  • The Benefits of Flavonoids in Diabetic Retinopathy.

    abstract：:Diabetic retinopathy (DR), one of the most common complications of diabetes, is the leading cause of legal blindness among adults of working age in developed countries. After 20 years of diabetes, almost all patients suffering from type I diabetes mellitus and about 60% of type II diabetics have DR. Several studies ha...

    journal_title：Nutrients

    pub_type： 杂志文章,评审

    doi：10.3390/nu12103169

    authors： Matos AL,Bruno DF,Ambrósio AF,Santos PF

    更新日期：2020-10-16 00:00:00

  • Risk of Kidney Stones: Influence of Dietary Factors, Dietary Patterns, and Vegetarian-Vegan Diets.

    abstract：:Nephrolithiasis is a common medical condition influenced by multiple environmental factors, including diet. Since nutritional habits play a relevant role in the genesis and recurrence of kidney stones disease, dietary manipulation has become a fundamental tool for the medical management of nephrolithiasis. Dietary adv...

    journal_title：Nutrients

    pub_type： 杂志文章,评审

    doi：10.3390/nu12030779

    authors： Ferraro PM,Bargagli M,Trinchieri A,Gambaro G

    更新日期：2020-03-15 00:00:00

  • Triple Adaptation of the Mediterranean Diet: Design of A Meal Plan for Older People with Oropharyngeal Dysphagia Based on Home Cooking.

    abstract：BACKGROUND:Oropharyngeal dysphagia (OD) and malnutrition are highly prevalent in older patients that are discharged from general hospitals (47% and 30%, respectively). AIMS:To develop a nutritional plan for these patients involving a triple adaptation of their traditional diet: (a) rheological adaptation (texture and ...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu11020425

    authors： Costa A,Carrión S,Puig-Pey M,Juárez F,Clavé P

    更新日期：2019-02-18 00:00:00

  • A Novel Micronutrient Blend Mimics Calorie Restriction Transcriptomics in Multiple Tissues of Mice and Increases Lifespan and Mobility in C. elegans.

    abstract：BACKGROUND:We previously described a novel micronutrient blend that behaves like a putative calorie restriction mimetic. The aim of this paper was to analyze the beneficial effects of our micronutrient blend in mice and C. elegans, and compare them with calorie restriction. METHODS:Whole transcriptomic analysis was pe...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu12020486

    authors： Serna E,Mastaloudis A,Martorell P,Wood SM,Hester SN,Bartlett M,Prolla TA,Viña J

    更新日期：2020-02-14 00:00:00

  • Influence of Maternal Fish Intake on the Anthropometric Indices of Children in the Western Amazon.

    abstract：:We studied trends in fish intake among pregnant women living in the Madeira River Basin in Rondônia State, Brazil, to investigate the influence of maternal fish intake on anthropometric indices of children followed up to 5 years. Maternal fish intake was assessed using hair mercury concentrations of mothers and childr...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu10091146

    authors： Cunha MPL,Marques RC,Dórea JG

    更新日期：2018-08-23 00:00:00

  • Spices and Atherosclerosis.

    abstract：:Cardiovascular disease is one of the leading causes of death and disability in the world. Atherosclerosis, characterized by lipid accumulation and chronic inflammation in the vessel wall, is the main feature of cardiovascular disease. Although the amounts of fruits and vegetables present in the diets vary by country, ...

    journal_title：Nutrients

    pub_type： 杂志文章,评审

    doi：10.3390/nu10111724

    authors： Tsui PF,Lin CS,Ho LJ,Lai JH

    更新日期：2018-11-10 00:00:00

  • Taste Receptors in Upper Airway Innate Immunity.

    abstract：:Taste receptors, first identified on the tongue, are best known for their role in guiding our dietary preferences. The expression of taste receptors for umami, sweet, and bitter have been demonstrated in tissues outside of the oral cavity, including in the airway, brain, gastrointestinal tract, and reproductive organs...

    journal_title：Nutrients

    pub_type： 杂志文章,评审

    doi：10.3390/nu11092017

    authors： Carey RM,Lee RJ

    更新日期：2019-08-28 00:00:00

  • Agrp-Specific Ablation of Scly Protects against Diet-Induced Obesity and Leptin Resistance.

    abstract：:Selenium, an essential trace element known mainly for its antioxidant properties, is critical for proper brain function and regulation of energy metabolism. Whole-body knockout of the selenium recycling enzyme, selenocysteine lyase (Scly), increases susceptibility to metabolic syndrome and diet-induced obesity in mice...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu11071693

    authors： Torres DJ,Pitts MW,Hashimoto AC,Berry MJ

    更新日期：2019-07-23 00:00:00