Abstract：
:Onchocerciasis (river blindness) is a blinding parasitic disease that threatens the health of approximately 120 million people worldwide. While 99% of the population at-risk for infection from onchocerciasis live in Africa, some 500,000 people in the Americas are also threatened by infection. A relatively recent arrival to the western hemisphere, onchocerciasis was brought to the New World through the slave trade and spread through migration. The centuries since its arrival have seen advances in diagnosing, mapping and treating the disease. Once endemic to six countries in the Americas (Brazil, Colombia, Ecuador, Guatemala, Mexico and Venezuela), onchocerciasis is on track for interruption of transmission in the Americas by 2012, in line with Pan American Health Organization resolution CD48.R12. The success of this public health program is due to a robust public-private partnership involving national governments, local communities, donor organizations, intergovernmental bodies, academic institutions, non-profit organizations and the pharmaceutical industry. The lessons learned through the efforts in the Americas are in turn informing the program to control and eliminate onchocerciasis in Africa. However, continued support and investment are needed for program implementation and post-treatment surveillance to protect the gains to-date and ensure complete elimination is achieved and treatment can be safely stopped within all 13 regional foci.
journal_name
Parasit Vectorsjournal_title
Parasites & vectorsauthors
Gustavsen K,Hopkins A,Sauerbrey Mdoi
10.1186/1756-3305-4-205subject
Has Abstractpub_date
2011-10-25 00:00:00pages
205issn
1756-3305pii
1756-3305-4-205journal_volume
4pub_type
杂志文章,评审abstract：BACKGROUND:Alternative splicing (AS) of mRNA is a vital mechanism for enhancing genomic complexity in eukaryotes. Spliced isoforms of the same gene can have diverse molecular and biological functions and are often differentially expressed across various tissues, times, and conditions. Thus, AS has important implication...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-151
更新日期：2014-04-01 00:00:00
abstract：BACKGROUND:Whipworms (Nematoda: Trichuridae), among the most common soil-transmitted helminths (STHs), can cause the socioeconomically important disease trichuriasis in various mammalian hosts including humans and non-human primates. For many years, Trichuris from non-human primates has been assigned to the same specie...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-3100-5
更新日期：2018-09-20 00:00:00
abstract：BACKGROUND:Prior work has shown that the levels of moxidectin in dogs treated with Advantage Multi® for Dogs (Bayer Animal Health) remain at a high plasma concentration for the full month after application. The objective of this study was to demonstrate the efficacy of 10% imidacloprid + 2.5% moxidectin topical solutio...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2432-x
更新日期：2017-11-09 00:00:00
abstract：BACKGROUND:Libyostrongylus douglassii, Libyostrongylus dentatus and Libyostrongylus magnus are nematodes that infect ostriches. The first species has been identified in ostriches from Africa, Europe, Americas and Oceania. Although the natural range of ostriches is Africa, L. dentatus was first described in birds from t...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-2815-7
更新日期：2018-04-13 00:00:00
abstract：BACKGROUND:The intestinal epithelium plays a multifactorial role in mucosal defense. In this sense, augmented epithelial cell turnover appears as a potential effector mechanism for the rejection of intestinal-dwelling helminths. METHODS:A BrdU pulse-chase experiment was conducted to investigate the infection-induced a...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0948-5
更新日期：2015-06-18 00:00:00
abstract：BACKGROUND:Fluralaner is a novel isoxazoline eliciting both acaricidal and insecticidal activity through potent blockage of GABA- and glutamate-gated chloride channels. The aim of the study was to investigate the susceptibility of juvenile stages of common tick species exposed to fluralaner through either contact (Rhip...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0704-x
更新日期：2015-02-08 00:00:00
abstract：BACKGROUND:Mosquito fitness is determined largely by body size and nutritional reserves. Plasmodium infections in the mosquito and resultant transmission of malaria parasites might be compromised by the vector's nutritional status. We studied the effects of nutritional stress and malaria parasite infections on transmis...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-6-345
更新日期：2013-12-10 00:00:00
abstract：BACKGROUND:Low-density asymptomatic infections of Plasmodium spp. are common in low endemicity areas worldwide, but outside Africa, their contribution to malaria transmission is poorly understood. Community-based studies with highly sensitive molecular diagnostics are needed to quantify the asymptomatic reservoir of Pl...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2407-y
更新日期：2017-10-24 00:00:00
abstract：BACKGROUND:Opisthorchiasis and Opisthorchis viverrini-associated bile duct cancer represent major public health threats in Thailand and Laos. The tegument of this food borne fluke plays pivotal roles in parasite metabolism, homeostasis and osmoregulation. Excretory/secretory products also pass from the fluke to the bil...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-224
更新日期：2014-05-14 00:00:00
abstract：BACKGROUND:Parasitic flatworms (Trematoda: Digenea) represent one of the most remarkable examples of drastic morphological diversity among the stages within a life cycle. Which genes are responsible for extreme differences in anatomy, physiology, behavior, and ecology among the stages? Here we report a comparative tran...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04424-4
更新日期：2020-11-10 00:00:00
abstract：BACKGROUND:Anopheles barbirostris sensu lato belongs to the Barbirostris subgroup of the subgenus Anopheles that is distributed in Southeast Asia. Different molecular forms have been identified based on the rDNA-ITS2 and mtDNA-COI sequences. Anopheles barbirostris occurs in China. The species status was uncertain due t...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-014-0592-5
更新日期：2014-12-16 00:00:00
abstract：BACKGROUND:Recent studies demonstrate that insect-specific viruses can influence the ability of their mosquito hosts to become infected with and transmit arboviruses of medical and veterinary importance. The aim of this study was to evaluate the interactions between Anopheles gambiae densovirus (AgDNV) (Parvoviridae) (...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04072-8
更新日期：2020-04-22 00:00:00
abstract：BACKGROUND:An accurate diagnosis of soil-transmitted helminthiasis is important for individual patient management, for drug efficacy evaluation and for monitoring control programmes. The Kato-Katz technique is the most widely used method detecting soil-transmitted helminth eggs in faecal samples. However, detailed anal...
journal_title：Parasites & vectors
pub_type： 杂志文章,随机对照试验
doi：10.1186/s13071-015-0702-z
更新日期：2015-02-05 00:00:00
abstract：BACKGROUND:Dengue has become the subject of public health programs worldwide. The lack of a vaccine and the high environmental risk of synthetic insecticides, arouse the interest in natural products against this vector. This study aimed to determine the chemical composition of the essential oil of ripe fruits and seeds...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0746-0
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND:Cutaneous Leishmaniasis (CL) is endemic in Sudan. It is caused by Leishmania major parasites and transmitted by Phlebotomus papatasi sandflies. Recently, uncommon clinical manifestations of CL have been reported. Moreover, L. donovani parasites that cause Visceral Leishmaniasis (VL) have been isolated from C...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-5-249
更新日期：2012-11-12 00:00:00
abstract：BACKGROUND:Carboxylesterase overproduction is a frequently observed resistance mechanism of insects to organophosphate insecticides. As a major transmitter of human diseases, mosquitoes in the Culex pipiens complex have evolved 13 carboxylesterase alleles (Ester) that confer organophosphate resistance. Six alleles, Est...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-5-209
更新日期：2012-09-24 00:00:00
abstract：BACKGROUND:The survival of adult female Aedes mosquitoes is a critical component of their ability to transmit pathogens such as dengue viruses. One of the principal determinants of Aedes survival is temperature, which has been associated with seasonal changes in Aedes populations and limits their geographical distribut...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-6-351
更新日期：2013-12-12 00:00:00
abstract：BACKGROUND:Fleas (Siphonaptera) are the most clinically important ectoparasites of dogs and cats worldwide. Rising levels of pet ownership, climate change and globalisation are increasing the importance of a detailed understanding of the endemicity and prevalence of flea-borne pathogens. This requires continued surveil...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3326-x
更新日期：2019-02-06 00:00:00
abstract：BACKGROUND:Many cases of cutaneous leishmaniasis (CL) have been recorded in the Jenin District based on their clinical appearance. Here, their parasites have been characterized in depth. METHODS:Leishmanial parasites isolated from 12 human cases of CL from the Jenin District were cultured as promastigotes, whose DNA w...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-5-121
更新日期：2012-06-18 00:00:00
abstract：BACKGROUND:Reliable maps of the geographical distribution, number of infected individuals and burden estimates of schistosomiasis are essential tools to plan, monitor and evaluate control programmes. Large-scale disease mapping and prediction efforts rely on compiled historical survey data obtained from the peer-review...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-4-142
更新日期：2011-07-20 00:00:00
abstract：BACKGROUND:Rhipicephalus sanguineus is a ubiquitous tick responsible for transmitting Ehrlichia canis and most likely Anaplasma platys to dogs, as either single or co-infections. The objective of this study was to assess the effects of either simultaneous or sequential experimental infections with E. canis and A. platy...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-3-33
更新日期：2010-04-08 00:00:00
abstract：BACKGROUND:Environmental changes caused by urbanization can cause alterations in the ecology and behavior of sandflies and in the epidemiology of leishmaniasis. Geotechnological tools allow the analysis and recognition of spatiotemporal patterns by monitoring and mapping risk areas of this vector-borne disease. This st...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-364
更新日期：2014-08-15 00:00:00
abstract：BACKGROUND:Triatomines are blood-sucking vectors of Trypanosoma cruzi, the causative agent of Chagas disease. During feeding, triatomines surpass the skin host response through biomolecules present in their saliva. Dendritic cells (DCs) play a crucial role in the induction of the protection to aggressive agents, includ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1890-x
更新日期：2016-12-09 00:00:00
abstract：: The disinfectants TriGene, bleach, ethanol and liquid hand soap, and water and temperature were tested for their ability to kill bloodstream forms of Trypanosoma brucei, epimastigotes of Trypanosoma rangeli and promastigotes of Leishmania major. A 5-min exposure to 0.2% TriGene, 0.1% liquid hand soap and 0.05% bleach...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-1-35
更新日期：2008-09-22 00:00:00
abstract：BACKGROUND:Leishmaniasis represents an important public health problem in Brazil. The continuous process of urbanization and expansion of human activities in forest areas impacts natural habitats, modifying the ecology of some species of Leishmania, as well as its vectors and reservoirs and, consequently, changes the e...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-2742-7
更新日期：2018-03-07 00:00:00
abstract：BACKGROUND:The low prevalence of blood parasites in some bird species may be related to the habitats they frequent, the inexistence of the right host-parasite assemblage or the immunological capacity of the host. Here, we assess the parasite load of breeding populations of Eleonora's falcon (Falco eleonorae), a medium-...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0802-9
更新日期：2015-03-31 00:00:00
abstract：BACKGROUND:Fluralaner is a novel systemic ectoparasiticide for dogs and cats providing immediate and persistent flea- and tick-control after a single topical dose. Prescribing directions recommend waiting 72 h following topical administration before immersing dogs in water. The objective of this study was to determine ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2389-9
更新日期：2017-09-25 00:00:00
abstract：BACKGROUND:Polovodova method based on counting follicular dilatations estimates the number of egg-laying in mosquitoes. However, some researchers doubt the reliability of this method because of the absence of multiple dilatations in vectors after many gonotrophic cycles. It is in this context of controversy that our st...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0731-7
更新日期：2015-02-22 00:00:00
abstract：BACKGROUND:Schistosoma mansoni cercariae penetrate the skin by releasing excretory/secretory (E/S) products known as 0-3hRP, which are associated with immune modulation through Toll like receptor (TLR) signalling. Furthermore, these secretions contain Sm16, which when given to cells as a recombinant protein inhibits hu...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-014-0608-1
更新日期：2015-01-06 00:00:00
abstract：BACKGROUND:Aedes albopictus, the Asian tiger mosquito, is an exotic invasive species in Europe. It has substantial public health relevance due to its potential role in transmitting several human pathogens. Out of the European countries, Spain has one of the highest risk levels of autochthonous arbovirus transmission du...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3359-1
更新日期：2019-03-29 00:00:00
