Abstract:
BACKGROUND:Leishmaniasis represents an important public health problem in Brazil. The continuous process of urbanization and expansion of human activities in forest areas impacts natural habitats, modifying the ecology of some species of Leishmania, as well as its vectors and reservoirs and, consequently, changes the epidemiological pattern that contributes to the expansion of American cutaneous leishmaniasis in Brazil. Here, we discuss Lutzomyia (Nyssomyia) whitmani, the main vector of ACL, transmitting two dermotropic Leishmania species including Leishmania (Viannia) braziliensis and Leishmania (V.) shawi. METHODS:We used the maximum entropy niche modelling approach (MaxEnt) to evaluate the environmental suitability of L. (N.) whitmani and the transmission of ACL in Brazil, in addition to designing models for a future scenario of climate change. MaxEnt was used under the "auto-features" mode and the default settings, with 100-fold repetition (bootstrap). The logistic output was used with higher values in the habitat suitability map, representing more favourable conditions for the occurrence of L. (N.) whitmani and human cases of ACL. RESULTS:Two models were developed: the Lutzomyia (N.) whitmani model (LWM) and the American cutaneous leishmaniasis model (ACLM). LWM identified the species "preferential habitat" included regions with moderate annual precipitation (AP) between 1000-1600 mm, intermediate vegetation density (NDVI) values, mean temperature of the coldest quarter (MTCQ), between 15-21 °C, and annual mean temperature (AMT), between 19-24 °C. ACLM indicates that ACL is strongly associated with areas of intermediate density vegetation, areas with AP between 800-1200 mm, MTCQ above 16 °C and AMT below 23 °C. CONCLUSIONS:The models generated for L. (N.) whitmani and ACL indicated a satisfactory predictive capacity. Future projections of LWM indicate an expansion of climatic suitability for L. (N.) whitmani for the northern and southern regions of Brazil. Future projections of ACL indicate the ongoing process of disease expansion in the face of the predicted climatic changes and reinforce the broad geographical expanse of this disease in Brazil. The models were able to identify that a continuous process of environmental degradation favours the establishment of L. (N.) whitmani and the occurrence of ACL by a strong association of the vector(s) and ACL to areas of intermediate vegetation cover density.
journal_name
Parasit Vectorsjournal_title
Parasites & vectorsauthors
da Costa SM,Cordeiro JLP,Rangel EFdoi
10.1186/s13071-018-2742-7subject
Has Abstractpub_date
2018-03-07 00:00:00pages
155issue
1issn
1756-3305pii
10.1186/s13071-018-2742-7journal_volume
11pub_type
杂志文章abstract:BACKGROUND:Rhipicephalus microplus is an efficient biological vector of Babesia bovis, a causative agent of bovine babesiosis. Babesia bovis is passed transovarially to the next generation of ticks, which then transmit the parasite to naïve animals. Due to the importance of the R. microplus ovary for tick reproduction ...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-018-3270-1
更新日期:2019-01-05 00:00:00
abstract:BACKGROUND:With the rapid spread of pyrethroid resistance in the main malaria vectors from Benin and the various resistance mechanisms involved (metabolic resistance and knock-down resistance (kdr), it is important to foresee effective resistance management strategies. Thus, the knowledge of the insensitive acetylcholi...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-6-274
更新日期:2013-09-21 00:00:00
abstract:BACKGROUND:Chagas disease transmission risk is a function of the presence of triatomines in domestic habitats. Rhodnius ecuadoriensis is one of the main vectors implicated in transmission of Trypanosoma cruzi in Ecuador. This triatomine species is present in domestic, peridomestic and sylvatic habitats in the country. ...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-5-17
更新日期:2012-01-13 00:00:00
abstract:BACKGROUND:Animal African trypanosomiasis (AAT) greatly affects livestock production in sub-Saharan Africa. In Ghana prevalence of AAT is estimated to range between 5 and 50%. Studies have reported serum biochemical aberrations and variability in cytokine profiles in animals during infection. However, information regar...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-017-2255-9
更新日期:2017-06-27 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1405-9
更新日期:2016-02-29 00:00:00
abstract:BACKGROUND:With field releases starting in Brazil, particular interest must be given to understanding how the endosymbiotic bacterium Wolbachia pipientis affects Aedes aegypti mosquitoes with a Brazilian genetic background. Currently, there is limited information on how the bacterium affects phenotypic traits such as l...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1559-5
更新日期:2016-05-16 00:00:00
abstract:BACKGROUND:NOD-like receptor protein 3 (NLRP3) inflammasome was reported as expressed in schistosomiasis-induced liver fibrosis (SSLF). We used an NLRP3 inflammasome inhibitor, MCC950, to investigate whether it inhibited liver fibrosis, and explored the preliminary molecular mechanism. METHODS:BALB/c mice were infecte...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-018-3223-8
更新日期:2019-01-11 00:00:00
abstract:BACKGROUND:Mutation of the voltage-gated sodium channel (VGSC) gene, or knockdown resistance (kdr) gene, is an important resistance mechanism against DDT and pyrethroids for dengue vector Aedes albopictus. A phenylalanine to serine (F1534S), leucine (F1534L) and cysteine (F1534C) substitution were detected in many Ae. ...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-019-3829-5
更新日期:2019-12-26 00:00:00
abstract:BACKGROUND:Prior work has shown that the levels of moxidectin in dogs treated with Advantage Multi® for Dogs (Bayer Animal Health) remain at a high plasma concentration for the full month after application. The objective of this study was to demonstrate the efficacy of 10% imidacloprid + 2.5% moxidectin topical solutio...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-017-2432-x
更新日期:2017-11-09 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-018-2815-7
更新日期:2018-04-13 00:00:00
abstract:BACKGROUND:Cyclospora is a protistan parasite that causes enteritis in several species of animals including humans. The aim of this study was to investigate the presence of Cyclospora in captive non-human primates. METHODS:A total of 119 faecal samples from Pan troglodytes, Macaca sylvanus, Cercopithecus cephus, Eryth...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-015-0872-8
更新日期:2015-05-15 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-015-0948-5
更新日期:2015-06-18 00:00:00
abstract::We report a Trichinella britovi outbreak investigated during February-March 2016 in southern Italy. The source of infection was meat from infected wild boars that were illegally hunted and, hence, not submitted to post-mortem veterinary inspection. Thirty persons reported having eaten raw dried homemade sausages; five...
journal_title:Parasites & vectors
pub_type: 信件
doi:10.1186/s13071-017-2052-5
更新日期:2017-02-28 00:00:00
abstract:BACKGROUND:Rhipicephalus sanguineus (sensu lato) is a vector of canine babesiosis, anaplasmosis and ehrlichiosis. In order to reduce the chance of transmission of these diseases, an ectoparasiticide should rapidly repel or kill new infestations with this tick. The primary objective of the present study was to evaluate ...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1561-y
更新日期:2016-05-16 00:00:00
abstract:BACKGROUND:Small ruminants are important hosts for various tick species and tick-associated organisms, many of which are zoonotic. The aim of the present study was to determine the presence of tick-borne protozoans and bacteria of public health and veterinary significance in goats and wild Siberian roe deer (Capreolus ...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-019-3553-1
更新日期:2019-06-13 00:00:00
abstract:BACKGROUND:We have previously reported that progesterone (P4) has a direct in vitro effect on the scolex evagination and growth of Taenia solium cysticerci. Here, we explored the hypothesis that the P4 direct effect on T. solium might be mediated by a novel steroid-binding parasite protein. METHODS:By way of using imm...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-018-2703-1
更新日期:2018-03-09 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-4-24
更新日期:2011-02-26 00:00:00
abstract:BACKGROUND:Knowledge on the capacity of Australian ticks to carry Borrelia species is currently limited or missing. To evaluate the potential of ticks to carry bacterial pathogens and their DNA, it is imperative to have a robust workflow that maximises recovery of bacterial DNA within ticks in order to enable accurate ...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-017-2579-5
更新日期:2017-12-20 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1778-9
更新日期:2016-09-29 00:00:00
abstract:BACKGROUND:In 2011, we reported occurrence of natural human infections with Brugia pahangi, a filarial worm of dogs and cats, in a surburb of Kuala Lumpur, the capital city of Malaysia. Our preliminary entomological survey at that time suggested the mosquito species Armigeres subalbatus as the vector of the zoonotic in...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-6-219
更新日期:2013-07-30 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-020-4005-7
更新日期:2020-03-14 00:00:00
abstract:BACKGROUND:Cattle persistently infected with Babesia bovis are reservoirs for intra- and inter-herd transmission. Since B. bovis is considered a persistent infection, developing a reliable, high-throughput assay that detects antibody during all stages of the infection could be pivotal for establishing better control pr...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-017-2016-9
更新日期:2017-02-13 00:00:00
abstract::Schistosomiasis is a major disease of public health importance in humans occurring in 76 countries of the tropics and sub-tropics. In China, schistosomiasis japonica is one of the highest priorities in communicable disease control defined by the central government. Since 1970s, the habitats of Biomphalaria straminea, ...
journal_title:Parasites & vectors
pub_type: 杂志文章,评审
doi:10.1186/1756-3305-6-249
更新日期:2013-08-28 00:00:00
abstract:BACKGROUND:A plethora of evidence shows that activated microglia play a critical role in the pathogenesis of the central nervous system (CNS). Toxoplasmic encephalitis (TE) frequently occurs in HIV/AIDS patients. However, knowledge remains limited on the contributions of activated microglia to the pathogenesis of TE. ...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-7-372
更新日期:2014-08-15 00:00:00
abstract:BACKGROUND:Schistosoma japonicum is a parasitic flatworm that causes human schistosomiasis. Secreted extracellular vesicles (EVs) play a key role in pathogen-host interfaces. Previous studies have shown that S. japonicum adult worms can release microRNA (miRNA)-containing EVs, which can transfer their cargo to mammalia...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1845-2
更新日期:2016-11-08 00:00:00
abstract:BACKGROUND:The trypanosome diversity of the Brush-tailed Bettong (Bettongia penicillata), known locally as the woylie, has been further investigated. At a species level, woylies are critically endangered and have declined by 90% since 1999. The predation of individuals made more vulnerable by disease is thought to be t...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-6-121
更新日期:2013-04-26 00:00:00
abstract:BACKGROUND:Understanding local Anopheles species compositions and bionomic traits are vital for an effective malaria vector intervention strategy. Though eight malaria vectors, including species complexes, have been documented across the island of Sulawesi, Indonesia, a comprehensive survey linking morphological and mo...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-020-04252-6
更新日期:2020-07-29 00:00:00
abstract:BACKGROUND:Bluetongue virus (BTV) is transmitted by Culicoides biting midges and causes bluetongue (BT), a clinical disease observed primarily in sheep. BT has a detrimental effect on subsistence farmers in India, where hyperendemic outbreaks impact on smallholdings in the southern states of the country. In this study,...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-017-1992-0
更新日期:2017-01-31 00:00:00
abstract:BACKGROUND:The studies reported here were conducted to ascertain the efficacy of imidacloprid/flumethrin incorporated in a slow-release matrix collar, against infestations of dogs by fleas, ticks, mites and lice. Efficacy was evaluated against the flea Ctenocephalides felis felis, the ticks Rhipicephalus sanguineus, Ix...
journal_title:Parasites & vectors
pub_type: 杂志文章,随机对照试验
doi:10.1186/1756-3305-5-102
更新日期:2012-05-30 00:00:00
abstract:BACKGROUND:Schistosomiasis is a neglected tropical disease and drug-repurposing is a useful strategy to fill its exhausted drug development pipeline. The ferrocenyl analogue of chloroquine, ferroquine, is an antimalarial in late-stage drug development. The aim of the present work was to study the antischistosomal activ...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-7-424
更新日期:2014-09-04 00:00:00