Abstract：
BACKGROUND:The intestinal epithelium plays a multifactorial role in mucosal defense. In this sense, augmented epithelial cell turnover appears as a potential effector mechanism for the rejection of intestinal-dwelling helminths. METHODS:A BrdU pulse-chase experiment was conducted to investigate the infection-induced alterations on epithelial cell kinetics in hosts of high (mouse) and low (rat) compatibility with the intestinal trematode Echinostoma caproni. RESULTS:High levels of crypt-cell proliferation and tissue hyperplasia were observed in the ileum of infected mice, coinciding with the establishment of chronic infections. In contrast, the cell migration rate was about two times higher in the ileum of infected rats compared with controls, with no changes in tissue structure, indicating that an accelerated cell turnover is associated with worm expulsion. CONCLUSION:Our results indicate that E. caproni infection induces a rapid renewal of the intestinal epithelium in the low compatible host that may impair the establishment of proper, stable host-parasite interactions, facilitating worm clearance.
journal_name
Parasit Vectorsjournal_title
Parasites & vectorsauthors
Cortés A,Muñoz-Antoli C,Martín-Grau C,Esteban JG,Grencis RK,Toledo Rdoi
10.1186/s13071-015-0948-5subject
Has Abstractpub_date
2015-06-18 00:00:00pages
334issn
1756-3305pii
10.1186/s13071-015-0948-5journal_volume
8pub_type
杂志文章abstract：BACKGROUND:The East Route Project (ERP) of the South-to-North Water Diversion Project (SNWDP) stretches across schistosomiasis endemic and non-endemic areas in China, which may lead to the dispersal of Oncomelania hupensis, the intermediate host of Schistosoma japonicum, from permissive areas along the Yangtze River Ba...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-4004-8
更新日期：2020-03-19 00:00:00
abstract：BACKGROUND:Abundance and species composition of sympatric malaria vector species are the important factors governing transmission intensity. A widespread insecticidal bed net coverage may replace endophagic species with exophagic species. However, unique local environments also influence a vector population. This study...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-63
更新日期：2014-02-11 00:00:00
abstract：BACKGROUND:Pyrethroid resistance has been slower to emerge in Anopheles arabiensis than in An. gambiae s.s and An. funestus and, consequently, studies are only just beginning to unravel the genes involved. Permethrin resistance in An. arabiensis in Lower Moshi, Tanzania has been linked to elevated levels of both P450 m...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-274
更新日期：2014-06-19 00:00:00
abstract：BACKGROUND:This laboratory study compared the efficacy of Bravecto™ (fluralaner), formulated as a chewable tablet, with the efficacy of Advocate® (imidacloprid/moxidectin), formulated for topical administration, against naturally acquired generalized demodicosis in dogs. METHODS:Sixteen dogs, all diagnosed with genera...
journal_title：Parasites & vectors
pub_type： 杂志文章,随机对照试验
doi：10.1186/s13071-015-0775-8
更新日期：2015-03-28 00:00:00
abstract：BACKGROUND:The ability of blood-feeding arthropods to successfully acquire and transmit pathogens of medical and veterinary importance has been shown to be interfered with, or enhanced by, the arthropod's native microbiome. Mosquitoes transmit viruses, protozoan and filarial nematodes, the majority of which contribute ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04218-8
更新日期：2020-07-13 00:00:00
abstract：BACKGROUND:Ov16 serology is considered a reference method for Onchocerca volvulus epidemiological mapping. Given the suboptimal sensitivity of this test and the fact that seroconversion takes more than a year after infection, additional serological tests might be needed to guide onchocerciasis elimination programmes. R...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3308-z
更新日期：2019-01-28 00:00:00
abstract：BACKGROUND:Landscape structure can affect pathogen prevalence and persistence with consequences for human and animal health. Few studies have examined how reservoir host species traits may interact with landscape structure to alter pathogen communities and dynamics. Using a landscape of islands and mainland sites we in...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-3200-2
更新日期：2018-12-04 00:00:00
abstract：BACKGROUND:The aim of this study was to determine exposure to vector-borne pathogens (VBPs) in populations of dogs living on Greek islands in the Ionian and Aegean seas. METHODS:In total, 1154 dogs with different lifestyles and of varying ages and breeds were randomly sampled and examined for the presence of clinical ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04153-8
更新日期：2020-06-03 00:00:00
abstract：BACKGROUND:Trypanosomosis is a haemoprotozoan disease, mostly transmitted by the tsetse fly (Glossina spp.), it causes severe disease in humans and animals in Sub-Saharan Africa (SSA). The disease results in loss of livestock and agricultural productivity with severe socio-economic impacts. In Ethiopia, bovine trypanos...
journal_title：Parasites & vectors
pub_type： 杂志文章,meta分析
doi：10.1186/s13071-016-1404-x
更新日期：2016-03-10 00:00:00
abstract：BACKGROUND:Understanding the dispersal dynamics of invasive mosquito species is fundamental to improve vector surveillance and to target control efforts. Aedes albopictus has been deemed a poor flyer as its range of active dispersal is generally assumed to be limited to a few hundred metres, while laboratory studies su...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3837-5
更新日期：2019-12-12 00:00:00
abstract：BACKGROUND:Schistosoma japonicum is a parasitic flatworm that causes human schistosomiasis. Secreted extracellular vesicles (EVs) play a key role in pathogen-host interfaces. Previous studies have shown that S. japonicum adult worms can release microRNA (miRNA)-containing EVs, which can transfer their cargo to mammalia...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1845-2
更新日期：2016-11-08 00:00:00
abstract：BACKGROUND:Culex pipiens L. is the most widespread mosquito vector in temperate regions including North Africa. Cx. pipiens has two recognized forms or biotypes; pipiens and molestus are morphologically indistinguishable with distinct behavior and physiology that may influence their vectorial status. In our study, we p...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-5-83
更新日期：2012-04-27 00:00:00
abstract：BACKGROUND:Multiplicity and genetic diversity of Plasmodium falciparum infection might play a role in determining the clinical outcome of malaria infection and could be a fair reflection of the disease transmission rate. This study investigated the genetic diversity of P. falciparum and multiplicity of infection in rel...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1641-z
更新日期：2016-06-27 00:00:00
abstract：BACKGROUND:Plasmodium falciparum delayed clearance with the use of artemisinin-based combination therapy (ACTs) has been reported in some African countries. Single nucleotide polymorphisms (SNPs) in two genes, P. falciparum adaptor protein complex 2 mu subunit (pfap2mu) and ubiquitin specific protease 1 (pfubp1), have ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-2762-3
更新日期：2018-03-12 00:00:00
abstract：BACKGROUND:In Europe, hard ticks of the subgenus Pholeoixodes (Ixodidae: Ixodes) are usually associated with burrow-dwelling mammals and terrestrial birds. Reports of Pholeoixodes spp. from carnivores are frequently contradictory, and their identification is not based on key diagnostic characters. Therefore, the aims o...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2424-x
更新日期：2017-11-03 00:00:00
abstract：BACKGROUND:Cutaneous Leishmaniasis (CL) is endemic in Sudan. It is caused by Leishmania major parasites and transmitted by Phlebotomus papatasi sandflies. Recently, uncommon clinical manifestations of CL have been reported. Moreover, L. donovani parasites that cause Visceral Leishmaniasis (VL) have been isolated from C...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-5-249
更新日期：2012-11-12 00:00:00
abstract：BACKGROUND:The disease scabies, caused by the ectoparasitic mite, Sarcoptes scabiei, causes significant morbidity in humans and other mammals worldwide. However, there is limited data available regarding the molecular basis of host specificity and host-parasite interactions. Therefore, we sought to produce a draft geno...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-1198-2
更新日期：2015-11-10 00:00:00
abstract：BACKGROUND:Plasmodium vivax uses multiple ligand-receptor interactions for preferential invasion of human reticulocytes. Several of these ligands have been identified by in silico approaches based on the role displayed by their orthologs in other Plasmodium species during initial adhesion or invasion. However, the cell...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2185-6
更新日期：2017-05-18 00:00:00
abstract：: The proteasome inhibitor and anti-cancer drug bortezomib was tested for in vitro activity against bloodstream forms of Trypanosoma brucei. The concentrations of bortezomib required to reduce the growth rate by 50% and to kill all trypanosomes were 3.3 nM and 10 nM, respectively. In addition, bortezomib was 10 times m...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-2-29
更新日期：2009-07-07 00:00:00
abstract：BACKGROUND:Mosquitoes are vectors for diseases such as dengue, malaria and La Crosse virus that significantly impact the human population. When multiple mosquito species are present, the competition between species may alter population dynamics as well as disease spread. Two mosquito species, Aedes albopictus and Aedes...
journal_title：Parasites & vectors
pub_type： 杂志文章
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更新日期：2021-01-25 00:00:00
abstract：BACKGROUND:The prevalence of bovine babesiosis caused by Babesia divergens has been declining during the past decades in northeastern Hungary, and no cases have been observed since 2008. Infections of cattle with B. major and Theileria buffeli were hitherto reported in southern and western Europe. In other parts of the...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-434
更新日期：2014-09-11 00:00:00
abstract：BACKGROUND:In this study for the first time, a Dientamoeba fragilis protein profile by MALDI-TOF MS was created in order to identify specific markers for the application of this technology in the laboratory diagnosis of dientamoebiasis. In particular, one D. fragilis reference strain was used to create a reference spec...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2597-3
更新日期：2018-01-04 00:00:00
abstract：BACKGROUND:Taenia ovis is a tapeworm that is mainly transmitted between dogs and sheep. Although T. ovis infection is not a public health issue, it causes a great financial loss due to condemnation of carcasses. The first outbreak of T. ovis infection in China occurred in 2015. Reassessment of adverse effects of T. ov...
journal_title：Parasites & vectors
pub_type： 信件
doi：10.1186/s13071-016-1700-5
更新日期：2016-07-26 00:00:00
abstract：BACKGROUND:Recent reports have demonstrated the presence of Crimean-Congo hemorrhagic fever virus (CCHFV) genomic material in Hyalomma aegyptium ticks feeding primarily on tortoises belonging to the genus Testudo. This raises the question if these ticks and their hosts play a role in the natural transmission dynamics o...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04074-6
更新日期：2020-04-19 00:00:00
abstract：BACKGROUND:Recent studies demonstrate that insect-specific viruses can influence the ability of their mosquito hosts to become infected with and transmit arboviruses of medical and veterinary importance. The aim of this study was to evaluate the interactions between Anopheles gambiae densovirus (AgDNV) (Parvoviridae) (...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04072-8
更新日期：2020-04-22 00:00:00
abstract：:Mosquito salivary proteins are involved in several biological processes that facilitate their blood feeding and have also been reported to elicit an IgG response in vertebrates. A growing number of studies have focused on this immunological response for its potential use as a biological marker of exposure to arthropod...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-4-33
更新日期：2011-03-08 00:00:00
abstract：BACKGROUND:Equine trypanosomiases are complex infectious diseases with overlapping clinical signs defined by their mode of transmission. Despite their economic impacts, these diseases have been neglected by the scientific community, the veterinary authorities and regulatory organizations. To fill the observed knowledge...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04192-1
更新日期：2020-06-23 00:00:00
abstract：BACKGROUND:The current study shows the results of three years of IRS entomological monitoring (2016, before intervention; 2017 and 2018, after intervention) performed in Alibori and Donga, northern Benin. METHODS:Mosquito collections were performed on a monthly basis using human landing catches and pyrethrum spray cat...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3865-1
更新日期：2019-12-30 00:00:00
abstract：BACKGROUND:Babesia motasi is known as an etiological agent of human and ovine babesiosis. Diagnosis of babesiosis is traditionally performed by microscopy, examining Giemsa-stained thin peripheral blood smears. Rapid detection and accurate identification of species are desirable for clinical care and epidemiological st...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04246-4
更新日期：2020-07-29 00:00:00
abstract：BACKGROUND:Opisthorchiasis and Opisthorchis viverrini-associated bile duct cancer represent major public health threats in Thailand and Laos. The tegument of this food borne fluke plays pivotal roles in parasite metabolism, homeostasis and osmoregulation. Excretory/secretory products also pass from the fluke to the bil...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-224
更新日期：2014-05-14 00:00:00
