Abstract:
BACKGROUND:Low-density asymptomatic infections of Plasmodium spp. are common in low endemicity areas worldwide, but outside Africa, their contribution to malaria transmission is poorly understood. Community-based studies with highly sensitive molecular diagnostics are needed to quantify the asymptomatic reservoir of Plasmodium falciparum and P. vivax infections in Thai communities. METHODS:A cross-sectional survey of 4309 participants was conducted in three endemic areas in Kanchanaburi and Ratchaburi provinces of Thailand in 2012. The presence of P. falciparum and P. vivax parasites was determined using 18S rRNA qPCR. Gametocytes were also detected by pfs25 / pvs25 qRT-PCRs. RESULTS:A total of 133 individuals were found infected with P. vivax (3.09%), 37 with P. falciparum (0.86%), and 11 with mixed P. vivax/ P. falciparum (0.26%). The clear majority of both P. vivax (91.7%) and P. falciparum (89.8%) infections were not accompanied by any febrile symptoms. Infections with either species were most common in adolescent and adult males. Recent travel to Myanmar was highly associated with P. falciparum (OR = 9.0, P = 0.001) but not P. vivax infections (P = 0.13). A large number of P. vivax (71.5%) and P. falciparum (72.0%) infections were gametocyte positive by pvs25/pfs25 qRT-PCR. Detection of gametocyte-specific pvs25 and pfs25 transcripts was strongly dependent on parasite density. pvs25 transcript numbers, a measure of gametocyte density, were also highly correlated with parasite density (r 2 = 0.82, P < 0.001). CONCLUSIONS:Asymptomatic infections with Plasmodium spp. were common in western Thai communities in 2012. The high prevalence of gametocytes indicates that these infections may contribute substantially to the maintenance of local malaria transmission.
journal_name
Parasit Vectorsjournal_title
Parasites & vectorsauthors
Nguitragool W,Mueller I,Kumpitak C,Saeseu T,Bantuchai S,Yorsaeng R,Yimsamran S,Maneeboonyang W,Sa-Angchai P,Chaimungkun W,Rukmanee P,Puangsa-Art S,Thanyavanich N,Koepfli C,Felger I,Sattabongkot J,Singhasivanon Pdoi
10.1186/s13071-017-2407-ysubject
Has Abstractpub_date
2017-10-24 00:00:00pages
512issue
1issn
1756-3305pii
10.1186/s13071-017-2407-yjournal_volume
10pub_type
杂志文章abstract:BACKGROUND:Infective larvae of the worldwide occurring zoonotic roundworm T. canis exhibit a marked affinity to the nervous tissues of paratenic hosts. In humans, most cases of neurotoxocarosis are considered to be caused by larvae of T. canis as T. cati larvae have rarely been found in the CNS in previous studies. How...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-7-194
更新日期:2014-04-22 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章,评审
doi:10.1186/1756-3305-5-239
更新日期:2012-10-23 00:00:00
abstract:BACKGROUND:The cysteine proteinases in papaya latex have been shown to have potent anthelmintic properties in monogastric hosts such as rodents, pigs and humans, but this has not been demonstrated in ruminants. METHODS:In two experiments, sheep were infected concurrently with 5,000 infective larvae of Haemonchus conto...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-4-36
更新日期:2011-03-15 00:00:00
abstract:BACKGROUND:Malaria mosquitoes spend a considerable part of their life in the aquatic stage, rendering them vulnerable to interventions directed to aquatic habitats. Recent successes of mosquito larval control have been reported using environmental and biological tools. Here, we report the effects of shading by plants a...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-4-130
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-018-2996-0
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1739-3
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1854-1
更新日期:2016-11-02 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-015-0783-8
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-4-119
更新日期:2011-06-27 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
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更新日期:2014-10-12 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
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更新日期:2011-07-20 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-015-1185-7
更新日期:2015-11-14 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-018-3275-9
更新日期:2019-01-09 00:00:00
abstract::Presently, 45% of the total human population of Europe, as well as their domestic and companion animals, are exposed to the risk of vector-borne helminths (VBH) causing diseases. A plethora of intrinsic biological and extrinsic factors affect the relationship among helminths, vectors and animal hosts, in a constantly ...
journal_title:Parasites & vectors
pub_type: 杂志文章,评审
doi:10.1186/1756-3305-6-16
更新日期:2013-01-16 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1662-7
更新日期:2016-07-04 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-4-24
更新日期:2011-02-26 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-3-82
更新日期:2010-09-06 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1659-2
更新日期:2016-07-01 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
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journal_title:Parasites & vectors
pub_type: 杂志文章
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-017-2060-5
更新日期:2017-04-21 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
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更新日期:2020-09-10 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/1756-3305-7-340
更新日期:2014-07-22 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-019-3803-2
更新日期:2019-11-20 00:00:00
abstract:BACKGROUND:Free-living amoebae of the genus Acanthamoeba are cosmopolitan, widely distributed protozoans that cause a severe, vision-threatening corneal infection known as Acanthamoeba keratitis (AK). The majority of the increasing number of AK cases are associated with contact lens use. Appropriate eye hygiene and eff...
journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-020-04453-z
更新日期:2020-12-22 00:00:00
abstract:BACKGROUND:Aedes aegypti is a potential vector of West Nile, Japanese encephalitis, chikungunya, dengue and Zika viruses. Alternative control measurements of the vector are needed to overcome the problems of environmental contamination and chemical resistance. Xenorhabdus and Photorhabdus are symbionts in the intestine...
journal_title:Parasites & vectors
pub_type: 杂志文章
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更新日期:2017-09-21 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-016-1641-z
更新日期:2016-06-27 00:00:00
abstract:BACKGROUND:Porcine cysticercosis is an emerging agricultural problem in sub-Saharan Africa. This has been documented primarily through cross-sectional studies, however detailed knowledge of the transmission dynamics of this disease in sub-Saharan Africa is lacking. This study aims to describe seasonal variations in ser...
journal_title:Parasites & vectors
pub_type: 杂志文章
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更新日期:2014-12-04 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
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更新日期:2018-05-29 00:00:00
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journal_title:Parasites & vectors
pub_type: 杂志文章
doi:10.1186/s13071-019-3491-y
更新日期:2019-05-16 00:00:00