Abstract：
BACKGROUND:As resistance to insecticides increases in disease vectors, it has become exceedingly important to monitor populations for susceptibility. Most studies of field populations of Aedes aegypti have largely characterized resistance patterns at the spatial scale of the city or country, which may not be completely informative given that insecticide application occurs at the scale of the house or city block. Phenotypic resistance to pyrethroids dominates in Ae. aegypti, and it has been partially explained by mutations in the voltage-gated sodium channel gene. Here, we assess community-level patterns of four knockdown resistance (kdr) haplotypes (C1534/I1016, F1534/I1016, C1534/V1016 and F1534/V1016) in Ae. aegypti in 24 randomly chosen city blocks from a city in Yucatán State, Mexico, during both the dry and wet season and over two years. RESULTS:Three of the four haplotypes, C1534/I1016, C1534/V1016 and F1534/V1016 were heterogeneous between city blocks at all four sampling time points, and the double mutant haplotype, C1534/I1016, showed a significant increase following the wet season. The F1534/I1016 haplotype was rarely detected, similar to other studies. However, when haplotype frequencies were aggregated to a coarser spatial scale, the differences in space and time were obscured. CONCLUSIONS:Our results provide empirical evidence that the selection of kdr alleles is occurring at fine spatial scales, indicating that future studies should include this scale to better understand evolutionary processes of resistance in natural populations.
journal_name
Parasit Vectorsjournal_title
Parasites & vectorsauthors
Grossman MK,Rodriguez J,Barreiro AM,Lenhart A,Manrique-Saide P,Vazquez-Prokopec GMdoi
10.1186/s13071-018-3275-9subject
Has Abstractpub_date
2019-01-09 00:00:00pages
20issue
1issn
1756-3305pii
10.1186/s13071-018-3275-9journal_volume
12pub_type
杂志文章abstract：BACKGROUND:Intestinal schistosomiasis due to Schistosoma mansoni was mapped in Cameroon in the 1990s and preventive chemotherapy launched since 2005. A situation analysis conducted in 2011 revealed an increase in schistosomiasis transmission, especially in the equatorial part of the country, despite the fact that Biomp...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-2763-2
更新日期：2018-03-13 00:00:00
abstract：BACKGROUND:Arthropod-borne diseases are some of the most rapidly spreading diseases. Reducing the vector population is currently the only effective way to reduce case numbers. Central metabolic pathways are potential targets to control vector populations, but have not been well explored to this aim. The information ava...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1391-y
更新日期：2016-02-25 00:00:00
abstract：BACKGROUND:Schistosomiasis remains prevalent in Africa, Asia and South America with an estimated burden of 1.9 million disability-adjusted life years in 2016. Targeting snails as a key to success for schistosomiasis control has been widely approved, but the long-term quantitative effects of interventions on snail contr...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04273-1
更新日期：2020-08-05 00:00:00
abstract：BACKGROUND:Schistosoma mansoni venom allergen-like protein (SmVAL) is a gene family composed of 29 members divided into group 1 encoding proteins potentially secreted, and group 2 encoding intracellular components. Some members were found to be upregulated in the transition of germ ball - cercariae - day 3 schistosomul...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2144-2
更新日期：2017-05-08 00:00:00
abstract：BACKGROUND:Pathogenic intestinal protozoa infections are common in school-aged children in the developing world and they are frequently associated with malabsorption syndromes and gastrointestinal morbidity. Since diagnosis of these parasites is difficult, prevalence data on intestinal protozoa is scarce. METHODS:We c...
journal_title：Parasites & vectors
pub_type： 杂志文章,随机对照试验
doi：10.1186/1756-3305-6-3
更新日期：2013-01-04 00:00:00
abstract：BACKGROUND:Aedes albopictus, the Asian tiger mosquito, is an exotic invasive species in Europe. It has substantial public health relevance due to its potential role in transmitting several human pathogens. Out of the European countries, Spain has one of the highest risk levels of autochthonous arbovirus transmission du...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3359-1
更新日期：2019-03-29 00:00:00
abstract：BACKGROUND:Pyrenean chamois (Rupicapra pyrenaica pyrenaica) is a nearly monomorphic mountain ungulate with an unbiased sex-specific overwinter adult survival. Few differences in gastrointestinal parasitism have been reported by coprology as yet. This study aims to assess diversity, prevalence, intensity of infection an...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0774-9
更新日期：2015-03-18 00:00:00
abstract：BACKGROUND:Trypanosoma rangeli is a protozoan that infects a variety of mammalian hosts, including humans. Its main insect vector is Rhodnius prolixus and is found in several Latin American countries. The R. prolixus vector competence depends on the T. rangeli strain and the molecular interactions, as well as the insec...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-0736-2
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND:A plethora of evidence shows that activated microglia play a critical role in the pathogenesis of the central nervous system (CNS). Toxoplasmic encephalitis (TE) frequently occurs in HIV/AIDS patients. However, knowledge remains limited on the contributions of activated microglia to the pathogenesis of TE. ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-372
更新日期：2014-08-15 00:00:00
abstract：BACKGROUND:The invasive temperate mosquito Aedes japonicus japonicus is a potential vector for various infectious diseases and therefore a target of vector control measures. Even though established in Germany, it is unclear whether the species has already reached its full distribution potential. The possible range of t...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3366-2
更新日期：2019-03-25 00:00:00
abstract：BACKGROUND:The genus Marshallagia (Family Haemonchidae, subfamily Ostertagiinae) contains multiple species of nematodes parasitising the abomasum (or duodenum) of ruminants, in particular of Caprinae. Male specimens have been described to be polymorphic with the frequent/major morphotype initially described in the genu...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04265-1
更新日期：2020-08-12 00:00:00
abstract：BACKGROUND:Multiplicity and genetic diversity of Plasmodium falciparum infection might play a role in determining the clinical outcome of malaria infection and could be a fair reflection of the disease transmission rate. This study investigated the genetic diversity of P. falciparum and multiplicity of infection in rel...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1641-z
更新日期：2016-06-27 00:00:00
abstract：:Companion vector-borne diseases (CVBDs) are an important threat for pet life, but may also have an impact on human health, due to their often zoonotic character. The importance and awareness of CVBDs continuously increased during the last years. However, information on their occurrence is often limited in several part...
journal_title：Parasites & vectors
pub_type： 杂志文章,评审
doi：10.1186/s13071-019-3407-x
更新日期：2019-03-28 00:00:00
abstract：BACKGROUND:The common cockle Cerastoderma edule plays an important ecological role in the marine ecosystem both as an infaunal engineer (reef forming and bioturbation) and a food source for protected bird species in its European range. Cockle beds are found in close proximity to aquaculture and fisheries operations, wh...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04373-y
更新日期：2020-10-01 00:00:00
abstract：BACKGROUND:Understanding the variation in prevalence of Borrelia burgdorferi sensu lato (Lyme Borreliosis Spirochaetes, LBS) and Anaplasma phagocytophilum (causing tick-borne fever in ruminants and human granulocytic ehrlichiosis) in ticks is vital from both a human and an animal disease perspective to target the most ...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-6-187
更新日期：2013-06-20 00:00:00
abstract：BACKGROUND:Landscape structure can affect pathogen prevalence and persistence with consequences for human and animal health. Few studies have examined how reservoir host species traits may interact with landscape structure to alter pathogen communities and dynamics. Using a landscape of islands and mainland sites we in...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-3200-2
更新日期：2018-12-04 00:00:00
abstract：BACKGROUND:Digenean trematodes are parasitic platyhelminths that use several hosts in their life cycles and are thereby embedded in various ecosystems affected by local environmental conditions. Their presence in a habitat will reflect the presence of different host species and, as such, they can serve as ecological in...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04536-x
更新日期：2021-01-12 00:00:00
abstract：BACKGROUND:Rickettsiae are emerging pathogens causing public health problems in many countries around the world. Rickettsia spp. are found in association with a wide range of arthropods which feed on different species of animals. However, the distribution and natural cycle of Rickettsia species and their association wi...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-018-2947-9
更新日期：2018-06-28 00:00:00
abstract：BACKGROUND:The myxosporean parasite Parvicapsula pseudobranchicola commonly infects farmed Atlantic salmon in northern Norway. Heavy infections are associated with pseudobranch lesions, runting and mortality in the salmon populations. The life-cycle of the parasite is unknown, preventing controlled challenge experiment...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2583-9
更新日期：2018-01-06 00:00:00
abstract：BACKGROUND:Dengue is a serious public health problem worldwide, including in Selangor, Malaysia. Being an important vector of dengue virus, Aedes aegypti are subjected to control measures which rely heavily on the usage of insecticides. Evidently, insecticide resistance in Ae. aegypti, which arise from several differen...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3472-1
更新日期：2019-05-16 00:00:00
abstract：BACKGROUND:The disease scabies, caused by the ectoparasitic mite, Sarcoptes scabiei, causes significant morbidity in humans and other mammals worldwide. However, there is limited data available regarding the molecular basis of host specificity and host-parasite interactions. Therefore, we sought to produce a draft geno...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-1198-2
更新日期：2015-11-10 00:00:00
abstract：BACKGROUND:Equine trypanosomiases are complex infectious diseases with overlapping clinical signs defined by their mode of transmission. Despite their economic impacts, these diseases have been neglected by the scientific community, the veterinary authorities and regulatory organizations. To fill the observed knowledge...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-04192-1
更新日期：2020-06-23 00:00:00
abstract：BACKGROUND:Understanding the dispersal dynamics of invasive mosquito species is fundamental to improve vector surveillance and to target control efforts. Aedes albopictus has been deemed a poor flyer as its range of active dispersal is generally assumed to be limited to a few hundred metres, while laboratory studies su...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-019-3837-5
更新日期：2019-12-12 00:00:00
abstract：BACKGROUND:Knowledge of insecticide resistance status in the main malaria vectors is an essential component of effective malaria vector control. This study presents the first evaluation of the status of insecticide resistance in Anopheles gambiae populations from Bangui, the Central African Republic. METHODS:Anopheles...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-016-1965-8
更新日期：2017-01-13 00:00:00
abstract：BACKGROUND:Dirofilaria immitis is a mosquito-borne pathogen that is spreading worldwide, and the associated infection (i.e. dirofilariosis) is becoming a threat to animals and humans living in endemic areas. Little is known about the occurrence and risk of infection of D. immitis in pinnipeds. Here we report dirofilari...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2073-0
更新日期：2017-03-13 00:00:00
abstract：BACKGROUND:Schistosomiasis, caused by schistosomes, is one of the most prevalent and serious parasitic diseases in tropical and subtropical countries. This pathogen has a complex life cycle and harbors a unique repertoire of genes expressed at different life-stages. Understanding the gene regulation of schistosomes wil...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-015-1203-9
更新日期：2015-11-14 00:00:00
abstract：BACKGROUND:The population dynamics of vector-borne pathogens inside the arthropod vector can have important consequences for vector-to-host transmission. Tick-borne spirochete bacteria of the Borrelia burgdorferi (sensu lato) species complex cause Lyme borreliosis in humans and spend long periods of time (>12 months) i...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-017-2187-4
更新日期：2017-05-25 00:00:00
abstract：BACKGROUND:The role of endemic murid rodents as hosts of arthropod vectors of diseases of medical and veterinary significance is well established in the northern hemisphere. In contrast, endemic murids are comparatively understudied as vector hosts in Africa, particularly in South Africa. Considering the great rodent d...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-7-366
更新日期：2014-08-15 00:00:00
abstract：BACKGROUND:Trichinella nematodes are globally distributed food-borne pathogens, in which Trichinella spiralis is the most common species in China. Microsatellites are a powerful tool in population genetics and phylogeographic analysis. However, only a few microsatellite markers were reported in T. spiralis. Thus, there...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/s13071-020-3929-2
更新日期：2020-02-11 00:00:00
abstract：BACKGROUND:One of the major issues concerning disease ecology and conservation is knowledge of the factors that influence the distribution of parasites and consequently disease outbreaks. This study aimed to investigate avian haemosporidian composition and the distribution of these parasites in three altitudinally sepa...
journal_title：Parasites & vectors
pub_type： 杂志文章
doi：10.1186/1756-3305-6-139
更新日期：2013-05-07 00:00:00
