当前位置： SCI文献检索 > Parasites & Vectors期刊下所有文献 > Rhodnius prolixus interaction with Trypanosoma rangeli: modulation of the immune system and microbiota population.

Rhodnius prolixus interaction with Trypanosoma rangeli: modulation of the immune system and microbiota population.

Abstract：

BACKGROUND:Trypanosoma rangeli is a protozoan that infects a variety of mammalian hosts, including humans. Its main insect vector is Rhodnius prolixus and is found in several Latin American countries. The R. prolixus vector competence depends on the T. rangeli strain and the molecular interactions, as well as the insect's immune responses in the gut and haemocoel. This work focuses on the modulation of the humoral immune responses of the midgut of R. prolixus infected with T. rangeli Macias strain, considering the influence of the parasite on the intestinal microbiota. METHODS:The population density of T. rangeli Macias strain was analysed in different R. prolixus midgut compartments in long and short-term experiments. Cultivable and non-cultivable midgut bacteria were investigated by colony forming unit (CFU) assays and by 454 pyrosequencing of the 16S rRNA gene, respectively. The modulation of R. prolixus immune responses was studied by analysis of the antimicrobial activity in vitro against different bacteria using turbidimetric tests, the abundance of mRNAs encoding antimicrobial peptides (AMPs) defensin (DefA, DefB, DefC), prolixicin (Prol) and lysozymes (LysA, LysB) by RT-PCR and analysis of the phenoloxidase (PO) activity. RESULTS:Our results showed that T. rangeli successfully colonized R. prolixus midgut altering the microbiota population and the immune responses as follows: 1 - reduced cultivable midgut bacteria; 2 - decreased the number of sequences of the Enterococcaceae but increased those of the Burkholderiaceae family; the families Nocardiaceae, Enterobacteriaceae and Mycobacteriaceae encountered in control and infected insects remained the same; 3 - enhanced midgut antibacterial activities against Serratia marcescens and Staphylococcus aureus; 4 - down-regulated LysB and Prol mRNA levels; altered DefB, DefC and LysA depending on the infection (short and long-term); 5 - decreased PO activity. CONCLUSION:Our findings suggest that T. rangeli Macias strain modulates R. prolixus immune system and modifies the natural microbiota composition.

journal_name

Parasit Vectors

journal_title

Parasites & vectors

authors

Vieira CS,Mattos DP,Waniek PJ,Santangelo JM,Figueiredo MB,Gumiel M,da Mota FF,Castro DP,Garcia ES,Azambuja P

doi

10.1186/s13071-015-0736-2

subject

Has Abstract

pub_date

2015-03-01 00:00:00

pages

135

issn

1756-3305

pii

10.1186/s13071-015-0736-2

journal_volume

8

pub_type

杂志文章

相关文献

Parasites & Vectors文献大全
  • Ability of near-infrared spectroscopy and chemometrics to predict the age of mosquitoes reared under different conditions.

    abstract：BACKGROUND:Practical, field-ready age-grading tools for mosquito vectors of disease are urgently needed because of the impact that daily survival has on vectorial capacity. Previous studies have shown that near-infrared spectroscopy (NIRS), in combination with chemometrics and predictive modeling, can forecast the age ...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-020-04031-3

    authors： Ong OTW,Kho EA,Esperança PM,Freebairn C,Dowell FE,Devine GJ,Churcher TS

    更新日期：2020-03-30 00:00:00

  • Histological and parasitological distinctive findings in clinically-lesioned and normal-looking skin of dogs with different clinical stages of leishmaniosis.

    abstract：BACKGROUND:Normal-looking skin of dogs with leishmaniosis frequently shows microscopic lesions along with the presence of Leishmania amastigotes. However, histological lesions with or without detection of amastigotes might not occur in less severe clinical cases. In addition, comparative studies between paired clinical...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-017-2051-6

    authors： Ordeix L,Dalmau A,Osso M,Llull J,Montserrat-Sangrà S,Solano-Gallego L

    更新日期：2017-03-13 00:00:00

  • Altitudinal variation in haemosporidian parasite distribution in great tit populations.

    abstract：BACKGROUND:One of the major issues concerning disease ecology and conservation is knowledge of the factors that influence the distribution of parasites and consequently disease outbreaks. This study aimed to investigate avian haemosporidian composition and the distribution of these parasites in three altitudinally sepa...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/1756-3305-6-139

    authors： Rooyen Jv,Lalubin F,Glaizot O,Christe P

    更新日期：2013-05-07 00:00:00

  • Toll-like receptor activation by helminths or helminth products to alleviate inflammatory bowel disease.

    abstract：:Helminth infection may modulate the expression of Toll like receptors (TLR) in dendritic cells (DCs) and modify the responsiveness of DCs to TLR ligands. This may regulate aberrant intestinal inflammation in humans with helminthes and may thus help alleviate inflammation associated with human inflammatory bowel diseas...

    journal_title：Parasites & vectors

    pub_type： 杂志文章,评审

    doi：10.1186/1756-3305-4-186

    authors： Sun S,Wang X,Wu X,Zhao Y,Wang F,Liu X,Song Y,Wu Z,Liu M

    更新日期：2011-09-27 00:00:00

  • Evaluation of an ultraviolet LED trap for catching Anopheles and Culex mosquitoes in south-eastern Tanzania.

    abstract：BACKGROUND:Improved surveillance techniques are required to accelerate efforts against major arthropod-borne diseases such as malaria, dengue, filariasis, Zika and yellow-fever. Light-emitting diodes (LEDs) are increasingly used in mosquito traps because they improve energy efficiency and battery longevity relative to ...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-019-3673-7

    authors： Mwanga EP,Ngowo HS,Mapua SA,Mmbando AS,Kaindoa EW,Kifungo K,Okumu FO

    更新日期：2019-08-27 00:00:00

  • Efficacy of oral fluralaner for the treatment of canine generalized demodicosis: a molecular-level confirmation.

    abstract：BACKGROUND:Canine generalized demodicosis is a common parasitic disease caused by the proliferation of Demodex mites. The introduction of isoxazoline class treatments in veterinary dermatology has resulted in apparently effective treatment of generalized demodicosis. The objective of this study was to evaluate the effe...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-019-3521-9

    authors： Djuric M,Milcic Matic N,Davitkov D,Glavinic U,Davitkov D,Vejnovic B,Stanimirovic Z

    更新日期：2019-05-28 00:00:00

  • Seroprevalence of Toxoplasma gondii infection among horses in Tunisia.

    abstract：BACKGROUND:The present study was conducted to investigate the serological survey of Toxoplasma antibodies in local.horses from three major regions: a neighbourhood of a city in the North (Sidi Thabet), a neighbourhood of a city on the coast (Monastir) and a neighbourhood of a city in the middle (Battan) of Tunisia (Nor...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/1756-3305-4-218

    authors： Boughattas S,Bergaoui R,Essid R,Aoun K,Bouratbine A

    更新日期：2011-11-22 00:00:00

  • Fibrinogen-related proteins in ixodid ticks.

    abstract：BACKGROUND:Fibrinogen-related proteins with lectin activity are believed to be part of the tick innate immune system. Several fibrinogen-related proteins have been described and characterised mainly on the basis of their cDNA sequences while direct biochemical evidence is missing. One of them, the haemolymph lectin Dor...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/1756-3305-4-127

    authors： Sterba J,Dupejova J,Fiser M,Vancova M,Grubhoffer L

    更新日期：2011-07-05 00:00:00

  • Low diversity of Angiostrongylus cantonensis complete mitochondrial DNA sequences from Australia, Hawaii, French Polynesia and the Canary Islands revealed using whole genome next-generation sequencing.

    abstract：BACKGROUND:Rats (Rattus spp.) invaded most of the world as stowaways including some that carried the rat lungworm, Angiostrongylus cantonensis, the cause of eosinophilic meningoencephalitis in humans and other warm-blooded animals. A high genetic diversity of A. cantonensis based on short mitochondrial DNA regions is r...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-019-3491-y

    authors： Červená B,Modrý D,Fecková B,Hrazdilová K,Foronda P,Alonso AM,Lee R,Walker J,Niebuhr CN,Malik R,Šlapeta J

    更新日期：2019-05-16 00:00:00

  • Host-antibody inductivity of virulent Entamoeba histolytica and non-virulent Entamoeba moshkovskii in a mouse model.

    abstract：BACKGROUND:Despite similarities in morphology, gene and protein profiles, Entamoeba histolytica and E. moshkovskii show profound differences in pathogenicity. Entamoeba histolytica infection might result in amoebic dysentery and liver abscess, while E. moshkovskii causes only mild diarrhea. Extensive studies focus on r...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-019-3363-5

    authors： Khomkhum N,Leetachewa S,Pawestri AR,Moonsom S

    更新日期：2019-03-13 00:00:00

  • In vitro activity of fluralaner and commonly used acaricides against Dermanyssus gallinae isolates from Europe and Brazil.

    abstract：BACKGROUND:The poultry red mite Dermanyssus gallinae negatively impacts bird welfare and health, and interferes with egg production and quality, while emerging acaricide resistance limits control options. Fluralaner, a novel miticide for administration in drinking water, is approved for control of D. gallinae infestati...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-018-2956-8

    authors： Thomas E,Zoller H,Liebisch G,Alves LFA,Vettorato L,Chiummo RM,Sigognault-Flochlay A

    更新日期：2018-06-25 00:00:00

  • Onchocerciasis in the Americas: from arrival to (near) elimination.

    abstract：:Onchocerciasis (river blindness) is a blinding parasitic disease that threatens the health of approximately 120 million people worldwide. While 99% of the population at-risk for infection from onchocerciasis live in Africa, some 500,000 people in the Americas are also threatened by infection. A relatively recent arriv...

    journal_title：Parasites & vectors

    pub_type： 杂志文章,评审

    doi：10.1186/1756-3305-4-205

    authors： Gustavsen K,Hopkins A,Sauerbrey M

    更新日期：2011-10-25 00:00:00

  • Use of Multiple Displacement Amplification as Pre-polymerase Chain Reaction (Pre-PCR) to amplify genomic DNA of siphonapterids preserved for long periods in scientific collections.

    abstract：: The recently developed Multiple Displacement Amplification technique (MDA) allows for the production of a large quantity of high quality genomic DNA from low amounts of the original DNA. The goal of this study was to evaluate the performance of the MDA technique to amplify genomic DNA of siphonapterids that have been...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/1756-3305-3-86

    authors： Avelar DM,Linardi PM

    更新日期：2010-09-15 00:00:00

  • IL-33/ST2 axis is involved in disease progression in the spleen during Leishmania donovani infection.

    abstract：BACKGROUND:During infection with Leishmania donovani, parasite control is linked to the systemic Th1 immune response, but in infected organs (liver, spleen and bone marrow), the response differs according to the micro-environment. The pleiomorphic cytokine interleukin-33 (IL-33) exerts various roles during infection, e...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-020-04190-3

    authors： Lamberet A,Rostan O,Dion S,Jan A,Guegan H,Manuel C,Samson M,Gangneux JP,Robert-Gangneux F

    更新日期：2020-06-22 00:00:00

  • Age structure of bed bug (Heteroptera: Cimicidae) aggregations affects the nymphal feeding success.

    abstract：BACKGROUND:Bed bugs (Heteroptera: Cimicidae) are a group of blood-feeding ectoparasites. They mainly specialize on bats and birds, but a few species are important human pests. They exhibit several unique adaptations for their parasitic lifestyle. Among those, bed bug aggregations represent a striking example of a sub-s...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-019-3659-5

    authors： Balvín O,Chajma P,Naylor R

    更新日期：2019-08-13 00:00:00

  • A DAF-3 co-Smad molecule functions in Haemonchus contortus development.

    abstract：BACKGROUND:The Smad proteins function in TGF-β signalling transduction. In the model nematode Caenorhabditis elegans, the co-Smad, DAF-3 mediates R-Smads and performs a central role in DAF-7 signal transduction, regulating dauer formation and reproductive processes. Considering the divergent evolutionary patterns of th...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-019-3855-3

    authors： Di W,Liu L,Zhang T,Li F,He L,Wang C,Ahmad AA,Hassan M,Fang R,Hu M

    更新日期：2019-12-27 00:00:00

  • Prevalence of bovine trypanosomosis in Ethiopia: a meta-analysis.

    abstract：BACKGROUND:Trypanosomosis is a haemoprotozoan disease, mostly transmitted by the tsetse fly (Glossina spp.), it causes severe disease in humans and animals in Sub-Saharan Africa (SSA). The disease results in loss of livestock and agricultural productivity with severe socio-economic impacts. In Ethiopia, bovine trypanos...

    journal_title：Parasites & vectors

    pub_type： 杂志文章,meta分析

    doi：10.1186/s13071-016-1404-x

    authors： Leta S,Alemayehu G,Seyoum Z,Bezie M

    更新日期：2016-03-10 00:00:00

  • Unique PFK regulatory property from some mosquito vectors of disease, and from Drosophila melanogaster.

    abstract：BACKGROUND:Arthropod-borne diseases are some of the most rapidly spreading diseases. Reducing the vector population is currently the only effective way to reduce case numbers. Central metabolic pathways are potential targets to control vector populations, but have not been well explored to this aim. The information ava...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-016-1391-y

    authors： Nunes RD,Romeiro NC,De Carvalho HT,Moreira JR,Sola-Penna M,Silva-Neto MA,Braz GR

    更新日期：2016-02-25 00:00:00

  • Parasite fauna of wild Antillean manatees (Trichechus manatus manatus) of the Andean Region, Colombia.

    abstract：BACKGROUND:Antillean manatees (Trichechus manatus manatus) are large herbivorous aquatic mammals living in limited areas of South, Central and North America. As with other aquatic mammals, Antillean manatees can be infected by a variety of protozoan and metazoan parasites, some of them with zoonotic potential, which af...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-019-3448-1

    authors： Vélez J,Hirzmann J,Arévalo-González K,Lange MK,Seipp A,Gärtner U,Taubert A,Caballero S,Hermosilla C

    更新日期：2019-04-27 00:00:00

  • Controlled efficacy trial confirming toltrazuril resistance in a field isolate of ovine Eimeria spp.

    abstract：BACKGROUND:Coccidiosis due to Eimeria spp. infections in lambs causes increased mortality and substantial production losses, and anticoccidials are important for control of the infection. Anticoccidial resistance has been reported in poultry and swine, and we recently described reduced toltrazuril efficacy in ovine Eim...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-018-2976-4

    authors： Odden A,Enemark HL,Ruiz A,Robertson LJ,Ersdal C,Nes SK,Tømmerberg V,Stuen S

    更新日期：2018-07-05 00:00:00

  • Dissection of the gut microbiota in mothers and children with chronic Trichuris trichiura infection in Pemba Island, Tanzania.

    abstract：BACKGROUND:Soil-transmitted helminthiases are important neglected tropical diseases that result in a notably high number of disability-adjusted life years worldwide. Characterizing the interactions between the human intestinal microbiome and helminths is of interest in the development of alternative treatments that do ...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-021-04580-1

    authors： Chen H,Mozzicafreddo M,Pierella E,Carletti V,Piersanti A,Ali SM,Ame SM,Wang C,Miceli C

    更新日期：2021-01-19 00:00:00

  • Temporal fluctuations in the sero-prevalence of Taenia solium cysticercosis in pigs in Mbeya Region, Tanzania.

    abstract：BACKGROUND:Porcine cysticercosis is an emerging agricultural problem in sub-Saharan Africa. This has been documented primarily through cross-sectional studies, however detailed knowledge of the transmission dynamics of this disease in sub-Saharan Africa is lacking. This study aims to describe seasonal variations in ser...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-014-0574-7

    authors： Braae UC,Magnussen P,Lekule F,Harrison W,Johansen MV

    更新日期：2014-12-04 00:00:00

  • The first detected airline introductions of yellow fever mosquitoes (Aedes aegypti) to Europe, at Schiphol International airport, the Netherlands.

    abstract：BACKGROUND:Air-borne introduction of exotic mosquitoes to Schiphol airport in the Netherlands has been considered plausible based upon findings of mosquitoes in aircraft cabins during 2008, 2010 and 2011. Beginning in 2013, surveillance efforts at Schiphol had focused on promptly detecting accidental introductions at t...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-017-2555-0

    authors： Ibañez-Justicia A,Gloria-Soria A,den Hartog W,Dik M,Jacobs F,Stroo A

    更新日期：2017-12-08 00:00:00

  • Patterns of insecticide resistance and knock down resistance (kdr) in malaria vectors An. arabiensis, An. coluzzii and An. gambiae from sympatric areas in Senegal.

    abstract：BACKGROUND:Malaria vector control in Africa relies on insecticides targeting adult mosquito vectors via insecticide treated nets or indoor residual spraying. Despite the proven efficacy of these strategies, the emergence and rapid rise in insecticide resistance in malaria vectors raises many concerns about their sustai...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-016-1354-3

    authors： Niang el HA,Konaté L,Diallo M,Faye O,Dia I

    更新日期：2016-02-05 00:00:00

  • Neglected aspects of tick-borne rickettsioses.

    abstract：:Rickettsioses are among the oldest known infectious diseases. In spite of this, and of the extensive research carried out, many aspects of the biology and epidemiology of tick-borne rickettsiae are far from being completely understood. Their association with arthropod vectors, the importance of vertebrates as reservoi...

    journal_title：Parasites & vectors

    pub_type： 杂志文章,评审

    doi：10.1186/s13071-018-2856-y

    authors： Tomassone L,Portillo A,Nováková M,de Sousa R,Oteo JA

    更新日期：2018-04-24 00:00:00

  • The phlebotomine sand flies fauna in Parque Estadual do Rio Doce, Minas Gerais, Brazil.

    abstract：BACKGROUND:Phlebotomine sand flies are dipterans of the family Psychodidae. They are very important to veterinary medicine because some species are vectors of infective forms of Leishmania spp., the etiological agents of leishmaniasis. The Parque Estadual do Rio Doce is located in an area with constant reports of cases...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-015-1227-1

    authors： de Souza CF,Brazil RP,Bevilacqua PD,Andrade Filho JD

    更新日期：2015-12-02 00:00:00

  • Rapid on-site diagnosis of canine giardiosis: time versus performance.

    abstract：BACKGROUND:Infections by protozoans of the genus Giardia are a common cause of diarrhea in dogs. Canine giardiosis constitutes a disease with a zoonotic potential; however, it is often underestimated due to its challenging diagnosis. The objective of the study was to assess the diagnostic performance of an immunochroma...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-020-04422-6

    authors： Symeonidou I,Gelasakis AΙ,Miliotou AN,Angelou A,Arsenopoulos KV,Loukeri S,Papadopoulos E

    更新日期：2020-11-02 00:00:00

  • Modelling the impact of larviciding on the population dynamics and biting rates of Simulium damnosum (s.l.): implications for vector control as a complementary strategy for onchocerciasis elimination in Africa.

    abstract：BACKGROUND:In 2012, the World Health Organization set goals for the elimination of onchocerciasis transmission by 2020 in selected African countries. Epidemiological data and mathematical modelling have indicated that elimination may not be achieved with annual ivermectin distribution in all endemic foci. Complementary...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-018-2864-y

    authors： Routledge I,Walker M,Cheke RA,Bhatt S,Nkot PB,Matthews GA,Baleguel D,Dobson HM,Wiles TL,Basañez MG

    更新日期：2018-05-29 00:00:00

  • CD3+CD4negCD8neg (double negative) T lymphocytes and NKT cells as the main cytotoxic-related-CD107a+ cells in lesions of cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis.

    abstract：BACKGROUND:Cutaneous leishmaniasis (CL) is caused by Leishmania (Viannia) braziliensis, which infects dermal macrophages and dendritic cells, causing an intense immune-mediated-tissue inflammation and a skin ulcer with elevated borders that can heal spontaneously or after antimonial therapy. The resolution of lesions d...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/s13071-017-2152-2

    authors： Ferraz R,Cunha CF,Pimentel MIF,Lyra MR,Pereira-Da-Silva T,Schubach AO,Da-Cruz AM,Bertho AL

    更新日期：2017-05-03 00:00:00

  • The use of a Psoroptes ovis serodiagnostic test for the analysis of a natural outbreak of sheep scab.

    abstract：BACKGROUND:Sheep scab is a highly contagious disease of sheep caused by the ectoparasitic mite Psoroptes ovis. The disease is endemic in the UK and has significant economic impact through its effects on performance and welfare. Diagnosis of sheep scab is achieved through observation of clinical signs e.g. itching, prur...

    journal_title：Parasites & vectors

    pub_type： 杂志文章

    doi：10.1186/1756-3305-5-7

    authors： Burgess ST,Innocent G,Nunn F,Frew D,Kenyon F,Nisbet AJ,Huntley JF

    更新日期：2012-01-10 00:00:00