Changing patterns of malaria during 1996-2010 in an area of moderate transmission in southern Senegal.

abstract：BACKGROUND:The Cascades region, Burkina Faso, has a high malaria burden despite reported high insecticide-treated mosquito net (ITN) use. Human and vector activities outside the hours when indoor interventions offer direct protection from infectious bites potentially increase exposure risk to bites from malaria-transmi...

journal_title：Malaria journal

authors： Guglielmo F,Sanou A,Churcher T,Ferguson HM,Ranson H,Sherrard-Smith E

更新日期：2021-01-18 00:00:00

abstract：BACKGROUND:Heads of Government from Asia and the Pacific have committed to a malaria-free region by 2030. In 2015, the total number of confirmed cases reported to the World Health Organization by 22 Asia Pacific countries was 2,461,025. However, this was likely a gross underestimate due in part to incidence data not be...

journal_title：Malaria journal

authors： Mercado CE,Ekapirat N,Dondorp AM,Maude RJ

更新日期：2017-03-21 00:00:00

abstract：BACKGROUND:Malaria is a major public health problem in Uganda and the current policy recommends introduction of rapid diagnostic tests for malaria (RDTs) to facilitate effective case management. However, provision of RDTs in drug shops potentially raises a new set of issues, such as adherence to RDTs results, managemen...

journal_title：Malaria journal

authors： Mbonye AK,Clarke SE,Lal S,Chandler CI,Hutchinson E,Hansen KS,Magnussen P

更新日期：2015-11-14 00:00:00

abstract：BACKGROUND:The resistance of malaria parasites to sulphadoxine-pyrimethamine (SP) in 2007 led to the Malawi Ministry of Health changing to artemether-lumefantrine (AL) as first-line for uncomplicated malaria treatment. This study determined the efficacy and safety of AL for the treatment of uncomplicated Plasmodium fal...

journal_title：Malaria journal

authors： Dambe R,Sande J,Ali D,Chilima B,Dodoli W,Michelo C,Malenga G,Phiri KS

更新日期：2015-04-23 00:00:00

abstract：BACKGROUND:Shandong Province experienced a declining malaria trend of local-acquired transmission, but the increasing imported malaria remains a challenge. Therefore, understanding the epidemiological characteristics of malaria and the control and elimination strategy and interventions is needed for better planning to ...

journal_title：Malaria journal

authors： Kong X,Liu X,Tu H,Xu Y,Niu J,Wang Y,Zhao C,Kou J,Feng J

更新日期：2017-01-31 00:00:00

abstract：BACKGROUND:Universal coverage with long-lasting insecticidal mosquito nets (LLIN) or indoor residual spraying (IRS) of houses remain the primary strategies for the control of mosquito vectors of malaria. Pyrethroid resistant malaria vectors are widespread throughout sub-Saharan Africa and new insecticides with differen...

journal_title：Malaria journal

authors： Oxborough RM,N'Guessan R,Kitau J,Tungu PK,Malone D,Mosha FW,Rowland MW

更新日期：2015-09-17 00:00:00

abstract：BACKGROUND:Described here is the first population genetic study of Plasmodium malariae, the causative agent of quartan malaria. Although not as deadly as Plasmodium falciparum, P. malariae is more common than previously thought, and is frequently in sympatry and co-infection with P. falciparum, making its study increas...

journal_title：Malaria journal

authors： Bruce MC,Macheso A,McConnachie A,Molyneux ME

更新日期：2011-02-11 00:00:00

abstract：BACKGROUND:Knowledge of the ecological differences between the molecular forms of Anopheles gambiae and their sibling species, An. arabiensis might lead to understanding their unique contribution to disease transmission and to better vector control as well as to understanding the evolutionary forces that have separated...

journal_title：Malaria journal

authors： Yaro AS,Dao A,Adamou A,Crawford JE,Ribeiro JM,Gwadz R,Traoré SF,Lehmann T

更新日期：2006-03-22 00:00:00

abstract：BACKGROUND:Azithromycin (AZM) is a macrolide antibiotic that displays an excellent safety profile even in children and pregnant women and has been shown to have anti-malarial activity against blood stage Plasmodium falciparum. This study evaluated the transmission-blocking effect of AZM using a rodent malaria model. M...

journal_title：Malaria journal

authors： Shimizu S,Osada Y,Kanazawa T,Tanaka Y,Arai M

更新日期：2010-03-10 00:00:00

abstract：BACKGROUND:The objective of this project was to achieve high, sustainable levels of net coverage in a village in rural Tanzania by combining free distribution of long-lasting insecticide-impregnated nets (LLINs) with community-tailored education. In Tanzania, malaria is the leading cause of morbidity and mortality. Alt...

journal_title：Malaria journal

authors： Widmar M,Nagel CJ,Ho DY,Benziger PW,Hennig N

更新日期：2009-12-31 00:00:00

abstract：BACKGROUND:Drug resistance in Plasmodium falciparum is common in many endemic and other settings but there is no clear recommendation on when to change therapy when there is delay in parasite clearance after initiation of therapy in African children. METHODS:The factors contributing to delay in parasite clearance, def...

journal_title：Malaria journal

authors： Sowunmi A,Adewoye EO,Gbotsho GO,Happi CT,Sijuade A,Folarin OA,Okuboyejo TM,Michael OS

更新日期：2010-02-15 00:00:00

abstract：BACKGROUND:The widespread use of indoor-based malaria vector control interventions has been shown to alter the behaviour of vectors in Africa. There is an increasing concern that such changes could sustain residual transmission. This study was conducted to assess vector species composition, feeding behaviour and their ...

journal_title：Malaria journal

authors： Degefa T,Yewhalaw D,Zhou G,Lee MC,Atieli H,Githeko AK,Yan G

更新日期：2017-11-06 00:00:00

abstract：BACKGROUND:Coverage of vulnerable groups with insecticide-treated nets (ITNs) in Ghana, as in the majority of countries of sub-Saharan Africa is currently low. A voucher scheme was introduced in Volta Region as a possible sustainable delivery system for increasing this coverage through scale-up to other regions. Succes...

journal_title：Malaria journal

authors： Kweku M,Webster J,Taylor I,Burns S,Dedzo M

更新日期：2007-02-02 00:00:00

abstract：BACKGROUND:Slash and burn cultivators are a significant risk group for malaria in South-East Asia. As envisaged in the National Strategic Plan for Malaria Elimination, Bangladesh aims to achieve zero indigenous malaria transmission by 2030. For the national plan to move from malaria control to malaria elimination, targ...

journal_title：Malaria journal

authors： Saha A,Sarker M,Kabir M,Lu G,Müller O

更新日期：2019-06-25 00:00:00

abstract：BACKGROUND:Rapid diagnostic tests (RDTs) for malaria provide a practical alternative to light microscopy for malaria diagnosis in resource-limited settings. Three-band RDTs incorporating two parasite antigens may have enhanced diagnostic specificity, relative to two-band RDTs with a single parasite antigen (typically h...

journal_title：Malaria journal

authors： Hawkes M,Conroy AL,Opoka RO,Namasopo S,Liles WC,John CC,Kain KC

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:This study aimed to identify factors at individual and community level influencing insecticide-treated net (ITN) usage among groups of women of childbearing age (WOCBA) in Malawi. METHODS:Factors influencing ITN usage in Malawi were assessed through interviews with 16,130 WOCBA (15-49 years) across 850 comm...

journal_title：Malaria journal

authors： Nkoka O,Chuang TW,Chuang KY,Chen YH

更新日期：2018-10-19 00:00:00

abstract：BACKGROUND:Anti-malarial drugs are the major focus in the prevention and treatment of malaria. Artemisinin-based combination therapy (ACT) is the WHO recommended first-line treatment for Plasmodium falciparum malaria across the endemic world. Also ACT is increasingly relied upon in treating Plasmodium vivax malaria whe...

journal_title：Malaria journal

authors： Njokah MJ,Kang'ethe JN,Kinyua J,Kariuki D,Kimani FT

更新日期：2016-07-22 00:00:00

abstract：BACKGROUND:In Plasmodium, the high level of genetic diversity and the interactions established by co-infecting parasite populations within the same host may be a source of selection on pathogen virulence and drug resistance. As different patterns have already been described in humans and mosquitoes, parasite diversity ...

journal_title：Malaria journal

authors： Mendes C,Salgueiro P,Gonzalez V,Berzosa P,Benito A,do Rosário VE,de Sousa B,Cano J,Arez AP

更新日期：2013-03-27 00:00:00

abstract：BACKGROUND:In 2009, Santa Isabel Province in the Solomon Islands embarked on a malaria elimination programme. However, very little is known in the Province about the anopheline fauna, which species are vectors, their bionomics and how they may respond to intensified intervention measures. The purpose of this study was ...

journal_title：Malaria journal

authors： Bugoro H,Iro'ofa C,Mackenzie DO,Apairamo A,Hevalao W,Corcoran S,Bobogare A,Beebe NW,Russell TL,Chen CC,Cooper RD

更新日期：2011-09-30 00:00:00

abstract：BACKGROUND:Automated detection of malaria and dengue infection has been actively researched for more than two decades. Although many improvements have been achieved, these solutions remain too expensive for most laboratories and clinics in developing countries. The low range HORIBA Medical Haematology Analyzer, Yumizen...

journal_title：Malaria journal

authors： Dharap P,Raimbault S

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:As the ecology of mosquito larvae can be complex there is need to develop a rational framework for undertaking larval ecological studies. Local environmental characteristics, such as altitude, climate and land use, can significantly impact on phenology and population dynamics of mosquito larvae, and indirect...

journal_title：Malaria journal

authors： Imbahale SS,Paaijmans KP,Mukabana WR,van Lammeren R,Githeko AK,Takken W

更新日期：2011-04-10 00:00:00

abstract：BACKGROUND:Kohat district is one of the medium intensity malaria transmission areas in Pakistan where asymptomatic carriers are likely to form a reservoir of infection. This study was done to explore the possibility of using microscopy, rapid diagnostic testing (RDT), real time polymerase chain reaction (RT-PCR) and RT...

journal_title：Malaria journal

authors： Naeem MA,Ahmed S,Khan SA

更新日期：2018-01-22 00:00:00

abstract：BACKGROUND:Studies in South-East Asia have suggested that early diagnosis and treatment with artesunate (AS) and mefloquine (MQ) combination therapy may reduce the transmission of Plasmodium falciparum malaria and the progression of MQ resistance. METHODS:The effectiveness of a fixed-dose combination of AS and MQ (ASM...

journal_title：Malaria journal

authors： Santelli AC,Ribeiro I,Daher A,Boulos M,Marchesini PB,dos Santos RL,Lucena MB,Magalhães I,Leon AP,Junger W,Ladislau JL

更新日期：2012-08-20 00:00:00

abstract：BACKGROUND:The Plasmodium falciparum multidrug resistance 1 transporter, PfMDR1, contains five amino acid polymorphisms that are suggested to be involved in altered drug transport from the parasite's cytosol into the digestive vacuole (DV). Transport of a substrate into another intracellular compartment influences drug...

journal_title：Malaria journal

authors： Reiling SJ,Rohrbach P

更新日期：2015-07-15 00:00:00

abstract：BACKGROUND:Plasmodium knowlesi is the fifth Plasmodium species that can infect humans. The Plasmodium merozoite surface protein-1(42) (MSP-1(42)) is a potential candidate for malaria vaccine. However, limited studies have focused on P. knowlesi MSP-1(42). METHODS:A ~42 kDa recombinant P. knowlesi MSP-1(42) (pkMSP-1(42...

journal_title：Malaria journal

authors： Cheong FW,Fong MY,Lau YL,Mahmud R

更新日期：2013-12-19 00:00:00

abstract：BACKGROUND:T1BT* is a peptide construct containing the T1 and B epitopes located in the 5' minor repeat and the 3' major repeat of the central repeat region of the Plasmodium falciparum circumsporozoite protein (CSP), respectively, and the universal T* epitope located in the C-terminus of the same protein. This peptide...

journal_title：Malaria journal

authors： Topchiy E,Armstrong GS,Boswell KI,Buchner GS,Kubelka J,Lehmann TE

更新日期：2013-03-18 00:00:00

abstract：BACKGROUND:Malaria is highly prevalent in many parts of India and is mostly caused by the parasite species Plasmodium vivax followed by Plasmodium falciparum. Chloroquine (CQ) is the first-line treatment for blood stage P. vivax parasites, but cases of drug resistance to CQ have been reported from India. One of the sur...

journal_title：Malaria journal

authors： Joy S,Mukhi B,Ghosh SK,Achur RN,Gowda DC,Surolia N

更新日期：2018-01-19 00:00:00

abstract：BACKGROUND:Anopheles arabiensis is stereotypical of diverse vectors that mediate residual malaria transmission globally, because it can feed outdoors upon humans or cattle, or enter but then rapidly exit houses without fatal exposure to insecticidal nets or sprays. METHODS:Life histories of a well-characterized An. ar...

journal_title：Malaria journal

authors： Killeen GF,Govella NJ,Lwetoijera DW,Okumu FO

更新日期：2016-04-19 00:00:00

abstract：:The classic formulae in malaria epidemiology are reviewed that relate entomological parameters to malaria transmission, including mosquito survivorship and age-at-infection, the stability index (S), the human blood index (HBI), proportion of infected mosquitoes, the sporozoite rate, the entomological inoculation rate ...

journal_title：Malaria journal

authors： Smith DL,McKenzie FE

更新日期：2004-06-04 00:00:00

abstract：BACKGROUND:The current status of insecticide resistance and the underlying resistance mechanisms were studied in the major vector of malaria, Anopheles culicifacies, and the secondary vector, Anopheles subpictus in five districts (Anuradhapura, Kurunegala, Moneragala, Puttalam and Trincomalee) of Sri Lanka. Eight other...

journal_title：Malaria journal

authors： Perera MD,Hemingway J,Karunaratne SP

更新日期：2008-08-28 00:00:00