Abstract:
BACKGROUND:Coverage of vulnerable groups with insecticide-treated nets (ITNs) in Ghana, as in the majority of countries of sub-Saharan Africa is currently low. A voucher scheme was introduced in Volta Region as a possible sustainable delivery system for increasing this coverage through scale-up to other regions. Successful scale-up of public health interventions depends upon optimal delivery processes but operational research for delivery processes in large-scale implementation has been inadequate. METHODS:A simple tool was developed to monitor numbers of vouchers given to each health facility, numbers issued to pregnant women by the health staff, and numbers redeemed by the distributors back to the management agent. Three rounds of interviews were undertaken with health facility staff, retailers and pregnant women who had attended antenatal clinic (ANC). RESULTS:During the one year pilot 25,926 vouchers were issued to eligible women from clinics, which equates to 50.7% of the 51,658 ANC registrants during this time period. Of the vouchers issued 66.7% were redeemed by distributors back to the management agent. Initially, non-issuing of vouchers to pregnant women was mainly due to eligibility criteria imposed by the midwives; later in the year it was due to decisions of the pregnant women, and supply constraints. These in turn were heavily influenced by factors external to the programme: current household ownership of nets, competing ITN delivery strategies, and competition for the limited number of ITNs available in the country from major urban areas of other regions. CONCLUSION:Both issuing and redemption of vouchers should be monitored as factors assumed to influence voucher redemption had an influence on issuing, and vice versa. More evidence is needed on how specific contextual factors influence the success of voucher schemes and other models of delivery of ITNs. Such an evidence base will facilitate optimal strategic decision making so that the delivery model with the best probability of success within a given context is implemented. Rigorous monitoring has an important role to play in the successful scaling-up of delivery of effective public health interventions.
journal_name
Malar Jjournal_title
Malaria journalauthors
Kweku M,Webster J,Taylor I,Burns S,Dedzo Mdoi
10.1186/1475-2875-6-14subject
Has Abstractpub_date
2007-02-02 00:00:00pages
14issn
1475-2875pii
1475-2875-6-14journal_volume
6pub_type
杂志文章相关文献
MALARIA JOURNAL文献大全abstract::Artemisinin, from which the artemether component of Coartem (artemether/lumefantrine, AL) is derived, is obtained from the plant sweet wormwood (Artemisia annua) which has been used for over 2,000 years as a Chinese herbal remedy. Artemisinin was first identified by Chinese researchers as the active anti-malarial cons...
journal_title:Malaria journal
pub_type: 杂志文章,评审
doi:10.1186/1475-2875-8-S1-S3
更新日期:2009-10-12 00:00:00
abstract:BACKGROUND:Mutations in Pfkelch13 and Pfplasmepsin2/3 gene amplification are well-established markers for artemisinin and piperaquine resistance in Plasmodium falciparum, a widespread problem in the Greater Mekong Subregion (GMS). The Plasmodium vivax parasite population has experienced varying drug pressure dependent ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-019-2749-3
更新日期:2019-04-02 00:00:00
abstract:BACKGROUND:The US FDA recently developed CD3+, a counterfeit detection tool that is based on sample illumination at specific wavelengths of light and visual comparison of suspect sample and packaging materials to an authentic sample. To test performance of the CD3+ in field conditions, a study was conducted in Ghana wh...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1180-2
更新日期:2016-02-25 00:00:00
abstract:BACKGROUND:Plasmodium ovale, considered the rarest of the malaria parasites of humans, consists of two morphologically identical but genetically distinct sympatric species, Plasmodium ovale curtisi and Plasmodium ovale wallikeri. These parasites resemble morphologically to Plasmodium vivax with which they also share a ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-0985-8
更新日期:2015-11-14 00:00:00
abstract:BACKGROUND:Rapid diagnostic tests (RDTs) have become an essential tool in the contemporary malaria control and management programmes in the world. This study aims to evaluate the performance of two commonly used RDTs for malaria diagnosis in the China-Myanmar border area. METHODS:A total 606 febrile patients in the Ch...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-12-73
更新日期:2013-02-22 00:00:00
abstract:BACKGROUND:Given the risk of artemisinin resistance spreading from the Greater Mekong sub-region, prospective monitoring in sub-Saharan Africa should be expedited. Molecular biology techniques used for monitoring rely on the detection of k13 validated mutants by using PCR and Sanger sequencing approach, usually not ava...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-018-2329-y
更新日期:2018-04-24 00:00:00
abstract:BACKGROUND:A malaria vaccine based on Plasmodium falciparum apical membrane antigen 1 (AMA1) elicited strain specific efficacy in Malian children that waned in the second season after vaccination despite sustained AMA1 antibody titers. With the goal of identifying a humoral correlate of vaccine-induced protection, pre-...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-019-2637-x
更新日期:2019-01-18 00:00:00
abstract:BACKGROUND:In the Tanga District of coastal Tanzania, malaria is one of the primary causes of mortality for children under the age of five. While some children are treated with malaria medications in biomedical facilities, as the World Health Organization recommends, others receive home-care or treatment from tradition...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-8-240
更新日期:2009-10-27 00:00:00
abstract:BACKGROUND:Azithromycin (AZM) is a macrolide antibiotic that displays an excellent safety profile even in children and pregnant women and has been shown to have anti-malarial activity against blood stage Plasmodium falciparum. This study evaluated the transmission-blocking effect of AZM using a rodent malaria model. M...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-9-73
更新日期:2010-03-10 00:00:00
abstract:BACKGROUND:Prompt and correct diagnosis of malaria is crucial for accurate epidemiological assessment and better case management, and while the gold standard of light microscopy is often available, it requires both expertise and time. Portable fluorescent microscopy using the CyScope offers a potentially quicker, easie...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-9-245
更新日期:2010-08-27 00:00:00
abstract:BACKGROUND:Early and accurate diagnosis of Plasmodium falciparum infection is important for providing appropriate treatment to patients with malaria. However, technical limitations of currently available diagnostic tests limit their use in control programs. One possible explanation for the vulnerability of current anti...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-277
更新日期:2014-07-18 00:00:00
abstract:BACKGROUND:Antiplasmodial activities of angiotensin II and its analogues have been extensively investigated in Plasmodium gallinaceum and Plasmodium falciparum parasite species. Due to its vasoconstrictor property angiotensin II cannot be used as an anti-malarial drug. METHODS:This work presents the solid-phase synthe...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-0974-y
更新日期:2015-11-04 00:00:00
abstract:BACKGROUND:Anti-malarial drugs are an important tool for malaria control and elimination. Alongside their direct benefit in the treatment of disease, drug use has a community-level effect, clearing the reservoir of infection and reducing onward transmission of the parasite. Different compounds potentially have differen...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1988-4
更新日期:2017-08-16 00:00:00
abstract:BACKGROUND:Recent progress in malaria control has caused renewed interest in mass drug administration (MDA) as a potential elimination strategy but the evidence base is limited. China has extensive experience with MDA, but it is not well documented. METHODS:An ecological study was conducted to describe the use of MDA ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-12-383
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Reported malaria cases continue to decline globally, and this has been attributed to strategic implementation of multiple malaria control tools. Gains made would however need to be sustained through continuous monitoring to ensure malaria elimination and eradication. Entomological inoculation rate (EIR) is c...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-103
更新日期:2014-03-17 00:00:00
abstract::April 25 marks World Malaria Day, an opportunity for those who work to defeat the illness, to review progress and renew commitments. After a decade of steady success, this year's commemoration of the date is also an opportunity to reconsider current approaches and assess the state of the science needed to keep pace in...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-12-140
更新日期:2013-04-24 00:00:00
abstract:BACKGROUND:Malaria is a major health problem in sub-Saharan Africa where over 90% of the world's malaria cases occur. Artemisinin-based combination therapy (ACT) is recommended by the World Health Organization as first-line and second-line treatments for uncomplicated falciparum malaria. However, there are a growing nu...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-018-2482-3
更新日期:2018-09-15 00:00:00
abstract:BACKGROUND:Molecular tools are very sensitive and specific and could be an alternative for the diagnosis of malaria. The complexity and need for expensive equipment may hamper implementation and, therefore, simplifications to current protocols are warranted. METHODS:A PCR detecting the different Plasmodium species and...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-11-279
更新日期:2012-08-17 00:00:00
abstract::Plasmodium falciparum infections present novel challenges for vaccine development, including parasite replication dynamics not previously encountered for viral pathogens, and enormous diversity in target antigens. These challenges are illustrated by using a mathematical model to describe the association between the pr...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-12-280
更新日期:2013-08-08 00:00:00
abstract:BACKGROUND:The reemergence of Plasmodium vivax in South Korea since 1993 represents a serious public health concern. Despite the importance in understanding genetic diversity for control strategies, however, studies remain inconclusive with the general premise that due to low rate of malaria transmission, there is gene...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-10-257
更新日期:2011-09-07 00:00:00
abstract::Artesunate (AS) is a clinically versatile artemisinin derivative utilized for the treatment of mild to severe malaria infection. Given the therapeutic significance of AS and the necessity of appropriate AS dosing, substantial research has been performed investigating the pharmacokinetics of AS and its active metabolit...
journal_title:Malaria journal
pub_type: 杂志文章,评审
doi:10.1186/1475-2875-10-263
更新日期:2011-09-13 00:00:00
abstract:BACKGROUND:The resistance of malaria parasites to sulphadoxine-pyrimethamine (SP) in 2007 led to the Malawi Ministry of Health changing to artemether-lumefantrine (AL) as first-line for uncomplicated malaria treatment. This study determined the efficacy and safety of AL for the treatment of uncomplicated Plasmodium fal...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-0701-8
更新日期:2015-04-23 00:00:00
abstract:BACKGROUND:Artemisinin-based combination therapy is the first-line anti-malarial treatment for uncomplicated Plasmodium falciparum infection in Angola. To date, the prevalence of polymorphisms in the pfk13 gene, associated with artemisinin resistance, and pfmdr1, associated with lumefantrine resistance, have not been s...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-018-2233-5
更新日期:2018-02-20 00:00:00
abstract:BACKGROUND:Control of vivax malaria in endemic areas requires management of recurrence. The Brazilian National Malaria Surveillance System (SIVEP-Malária) records every case of malaria in Brazil, but is not designed to differentiate between primary and recurrent infections. The aim of this study was to explore whether ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-019-2644-y
更新日期:2019-01-22 00:00:00
abstract::This meeting report presents the key findings and discussion points of a 1-day meeting entitled 'Fake anti-malarials: start with the facts' held on 28th May 2015, in Geneva, Switzerland, to disseminate the findings of the artemisinin combination therapy consortium's drug quality programme. The teams purchased over 10,...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1096-x
更新日期:2016-02-13 00:00:00
abstract:BACKGROUND:Plasmodium vivax is very rarely seen in West Africa, although specific detection methods are not widely applied in the region, and it is now considered to be absent from North Africa. However, this parasite species has recently been reported to account for most malaria cases in Nouakchott, the capital of Mau...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1118-8
更新日期:2016-02-09 00:00:00
abstract:BACKGROUND:Relatively little is known about the prevalence of blood parasites in shorebirds, especially those breeding in the tropics. The prevalence of blood parasites of the genera Plasmodium, Haemoproteus and Leucocytozoon was assessed in blood samples from Kentish plovers and cream-coloured coursers in Cape Verde, ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1892-y
更新日期:2017-06-08 00:00:00
abstract:BACKGROUND:Advances in digitized video-tracking and behavioural analysis have enabled accurate recording and quantification of mosquito flight and host-seeking behaviours, facilitating development of individual (agent) based models at much finer spatial scales than previously possible. METHODS:Quantified behavioural p...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-020-03546-5
更新日期:2021-01-07 00:00:00
abstract:BACKGROUND:Larviciding is a key strategy used in many vector control programmes around the world. Costs could be reduced if larvicides could be manufactured locally. The potential of natural products as larvicides against the main African malaria vector, Anopheles gambiae s.s was evaluated. METHODS:To assess the larvi...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-6-63
更新日期:2007-05-22 00:00:00
abstract:BACKGROUND:Policy makers, governments and donors are faced with an information gap when considering ways to improve access to artemisinin-based combination therapy (ACT) and malaria diagnostics including rapid diagnostic tests (RDTs). To help address some of these gaps, a five-year multi-country research project called...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-10-325
更新日期:2011-10-31 00:00:00