Recent increase of genetic diversity in Plasmodium vivax population in the Republic of Korea.

abstract：BACKGROUND:Reported malaria cases continue to decline globally, and this has been attributed to strategic implementation of multiple malaria control tools. Gains made would however need to be sustained through continuous monitoring to ensure malaria elimination and eradication. Entomological inoculation rate (EIR) is c...

journal_title：Malaria journal

authors： Kusi KA,Bosomprah S,Dodoo D,Kyei-Baafour E,Dickson EK,Mensah D,Angov E,Dutta S,Sedegah M,Koram KA

更新日期：2014-03-17 00:00:00

abstract：BACKGROUND:The standard in vitro protocol currently in use for drug testing against Plasmodium falciparum, based on the incorporation of the purine [3H]-hypoxanthine, has two serious drawbacks. Firstly it is unsuitable for the testing of drugs that directly or indirectly impact on purine salvage or metabolism. Secondly...

journal_title：Malaria journal

authors： Quashie NB,de Koning HP,Ranford-Cartwright LC

更新日期：2006-10-31 00:00:00

abstract：BACKGROUND:The use of rapid diagnostic tests (RDTs) to diagnose malaria is common in sub-Saharan African laboratories, remote primary health facilities and in the community. Currently, there is a lack of reliable methods to ascertain health worker competency to accurately use RDTs in the testing and diagnosis of malari...

journal_title：Malaria journal

authors： Dorkenoo AM,Kouassi KC,Koura AK,Adams ML,Gbada K,Katawa G,Yakpa K,Charlebois R,Milgotina E,Merkel MO,Aidoo M

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:Polymorphism in the pfcrt gene underlies Plasmodium falciparum chloroquine resistance (CQR), as sensitive strains consistently carry lysine (K), while CQR strains carry threonine (T) at the codon 76. Previous studies have shown that microsatellite (MS) haplotype variation can be used to study the evolution o...

journal_title：Malaria journal

authors： DaRe JT,Mehlotra RK,Michon P,Mueller I,Reeder J,Sharma YD,Stoneking M,Zimmerman PA

更新日期：2007-03-21 00:00:00

abstract：BACKGROUND:Malaria is a major public health problem in Uganda and the current policy recommends introduction of rapid diagnostic tests for malaria (RDTs) to facilitate effective case management. However, provision of RDTs in drug shops potentially raises a new set of issues, such as adherence to RDTs results, managemen...

journal_title：Malaria journal

authors： Mbonye AK,Clarke SE,Lal S,Chandler CI,Hutchinson E,Hansen KS,Magnussen P

更新日期：2015-11-14 00:00:00

abstract：BACKGROUND:Eradication of malaria is difficult because of the ability of hypnozoite, the dormant liver-stage form of Plasmodium vivax, to cause relapse in patients. Research efforts to better understand the biology of P. vivax hypnozoite and design relapse prevention strategies have been hampered by the lack of a robus...

journal_title：Malaria journal

authors： Pewkliang Y,Rungin S,Lerdpanyangam K,Duangmanee A,Kanjanasirirat P,Suthivanich P,Sa-Ngiamsuntorn K,Borwornpinyo S,Sattabongkot J,Patrapuvich R,Hongeng S

更新日期：2018-01-25 00:00:00

abstract：BACKGROUND:Malaria continues to be a disease of massive burden in Africa, and the public health resources targeted at surveillance, prevention, control, and intervention comprise large outlays of expense. Malaria transmission is largely constrained by the suitability of the climate for Anopheles mosquitoes and Plasmodi...

journal_title：Malaria journal

authors： Ryan SJ,Lippi CA,Zermoglio F

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Artemisinin is the current drug of choice for treatment of malaria and a number of other diseases. It is obtained from the annual herb, Artemisia annua and some microbial sources by genetic engineering. There is a great concern that the artemisinin production at current rate will not meet the increasing dema...

journal_title：Malaria journal

authors： Mannan A,Ahmed I,Arshad W,Asim MF,Qureshi RA,Hussain I,Mirza B

更新日期：2010-11-04 00:00:00

abstract：BACKGROUND:Improving the way artemether-lumefantrine (AL) is provided to patients attending clinics is critical to maximize the benefit of this new medicine. In 2007, a new initiative was launched in one part of Kenya to improve malaria case-management through enhanced in-service training and provision of job aids. ME...

journal_title：Malaria journal

authors： Wasunna B,Zurovac D,Bruce J,Jones C,Webster J,Snow RW

更新日期：2010-09-18 00:00:00

abstract：BACKGROUND:The relationship between mosquito development and temperature is one of the keys to understanding the current and future dynamics and distribution of vector-borne diseases such as malaria. Many process-based models use mean air temperature to estimate larval development times, and hence adult vector densitie...

journal_title：Malaria journal

authors： Paaijmans KP,Imbahale SS,Thomas MB,Takken W

更新日期：2010-07-09 00:00:00

abstract：BACKGROUND:Control of the major African malaria vector species continues to rely extensively on the application of residual insecticides through indoor house spraying or bed net impregnation. Insecticide resistance is undermining the sustainability of these control strategies. Alternatives to the currently available co...

journal_title：Malaria journal

authors： Kikankie CK,Brooke BD,Knols BG,Koekemoer LL,Farenhorst M,Hunt RH,Thomas MB,Coetzee M

更新日期：2010-03-08 00:00:00

abstract：BACKGROUND:A previous study reported that the malaria parasite Plasmodium falciparum enters an altered growth state upon extracellular withdrawal of the essential amino acid isoleucine. Parasites slowed transit through the cell cycle when deprived of isoleucine prior to the onset of S-phase. METHODS:This project was u...

journal_title：Malaria journal

authors： McLean KJ,Jacobs-Lorena M

更新日期：2020-04-08 00:00:00

abstract：BACKGROUND:Malaria is a leading cause of mortality and morbidity in Mozambique, with nearly three-quarters of the country's malaria-related deaths occurring in children younger than five years. A malaria vaccine is not yet available, but planning is underway for a possible introduction, as soon as one becomes available...

journal_title：Malaria journal

authors： Bingham A,Gaspar F,Lancaster K,Conjera J,Collymore Y,Ba-Nguz A

更新日期：2012-11-28 00:00:00

abstract：BACKGROUND:Mice with genetic deficiencies in adaptive immunity are used for the grafting of human cells or pathogens, to study human diseases, however, the innate immune responses to xenografts in these mice has received little attention. Using the NOD/SCID Plasmodium falciparum mouse model an analysis of innate defenc...

journal_title：Malaria journal

authors： Arnold L,Tyagi RK,Mejia P,Van Rooijen N,Pérignon JL,Druilhe P

更新日期：2010-07-09 00:00:00

abstract：BACKGROUND:Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1) antigens play a critical role in host immune evasion. Serologic responses to these antigens have been associated with protection from clinical malaria, suggesting that antibodies to PfEMP1 antigens may contribute to natural immunity. The first N-t...

journal_title：Malaria journal

authors： Stucke EM,Niangaly A,Berry AA,Bailey JA,Coulibaly D,Ouattara A,Lyke KE,Laurens MB,Dara A,Adams M,Pablo J,Jasinskas A,Nakajima R,Zhou AE,Agrawal S,Friedman-Klabanoff DJ,Takala-Harrison S,Kouriba B,Kone AK,Rowe JA,D

更新日期：2019-08-13 00:00:00

abstract：BACKGROUND:In south-eastern Senegal, malaria and onchocerciasis are co-endemic. Onchocerciasis in this region has been controlled by once or twice yearly mass drug administration (MDA) with ivermectin (IVM) for over fifteen years. Since laboratory-raised Anopheles gambiae s.s. are susceptible to ivermectin at concentra...

journal_title：Malaria journal

authors： Sylla M,Kobylinski KC,Gray M,Chapman PL,Sarr MD,Rasgon JL,Foy BD

更新日期：2010-12-20 00:00:00

abstract：BACKGROUND:Most malaria rapid diagnostic tests (RDTs) use HRP2 detection, including Paracheck-Pf(R), but their utility is limited by persistent false positivity after treatment. PLDH-based tests become negative more quickly, but sensitivity has been reported below the recommended standard of 90%. A new pLDH test, CareS...

journal_title：Malaria journal

authors： Gerstl S,Dunkley S,Mukhtar A,De Smet M,Baker S,Maikere J

更新日期：2010-01-21 00:00:00

abstract：BACKGROUND:Congenital malaria is the direct infection of an infant with malaria parasites from their mother prior to or during birth. Neonatal malaria is due to an infective mosquito bite after birth. Neonatal and congenital malaria (NCM) are potentially life-threatening conditions that are believed to occur at relativ...

journal_title：Malaria journal

authors： Olupot-Olupot P,Eregu EIE,Naizuli K,Ikiror J,Acom L,Burgoine K

更新日期：2018-04-20 00:00:00

abstract：BACKGROUND:Based on routine health facility case data, Rwanda has achieved a significant malaria burden reduction in the past ten years. However, community-based malaria parasitaemia burden and reasons for continued residual infections, despite a high coverage of control interventions, have yet to be characterized. Mea...

journal_title：Malaria journal

authors： Kateera F,Mens PF,Hakizimana E,Ingabire CM,Muragijemariya L,Karinda P,Grobusch MP,Mutesa L,van Vugt M

更新日期：2015-01-21 00:00:00

abstract：BACKGROUND:Traditional medicine is readily available in Tanzania, and local terms like degedege is widely used for malaria-like illnesses, often associated with supernatural forces. Malaria prevention and intervention efforts can benefit from policy-makers' awareness of local perceptions and beliefs in the rural areas ...

journal_title：Malaria journal

authors： Spjeldnæs AO,Kitua AY,Blomberg B

更新日期：2014-05-28 00:00:00

abstract：BACKGROUND:Malaria remains a major public health problem, and its control has been hampered by drug resistance. For a number of drugs, Plasmodium falciparum single nucleotide polymorphisms (SNPs) are associated with altered drug sensitivity and can be used as markers of drug resistance. Several techniques have been stu...

journal_title：Malaria journal

authors： Nankoberanyi S,Mbogo GW,LeClair NP,Conrad MD,Tumwebaze P,Tukwasibwe S,Kamya MR,Tappero J,Nsobya SL,Rosenthal PJ

更新日期：2014-03-14 00:00:00

abstract：BACKGROUND:The objective of this study was to identify attitudes and misconceptions related to acceptance or refusal of indoor residual spraying (IRS) in Tanzania for both the general population and among certain groups (e.g., farmers, fishermen, community leaders, and women). METHODS:This study was a series of qualit...

journal_title：Malaria journal

authors： Kaufman MR,Rweyemamu D,Koenker H,Macha J

更新日期：2012-07-02 00:00:00

abstract：BACKGROUND:With less than one severe case per year in average, Plasmodium vivax is very rarely associated with severe imported malaria in France. Two cases of P. vivax severe malaria occurred in patients with no evident co-morbidity. Interestingly, both cases did not occur at the primary infection but during relapses. ...

journal_title：Malaria journal

authors： Izri A,Cojean S,Leblanc C,Cohen Y,Bouchaud O,Durand R

更新日期：2019-12-16 00:00:00

abstract：BACKGROUND:Although it is well known that drug pressure selects for drug-resistant parasites, the role of transmission reduction by insecticide-treated bed nets (ITNs) on drug resistance remains unclear. In this study, the drug resistance profile of current and previous first-line anti-malarials in Kenya was assessed w...

journal_title：Malaria journal

authors： Shah M,Omosun Y,Lal A,Odero C,Gatei W,Otieno K,Gimnig JE,ter Kuile F,Hawley WA,Nahlen B,Kariuki S,Walker E,Slutsker L,Hamel M,Shi YP

更新日期：2015-02-14 00:00:00

abstract：BACKGROUND:Malaria transmission is strongly determined by the environmental temperature and the environment is rarely constant. Therefore, mosquitoes and parasites are not only exposed to the mean temperature, but also to daily temperature variation. Recently, both theoretical and laboratory work has shown, in addition...

journal_title：Malaria journal

authors： Zhao X,Chen F,Feng Z,Li X,Zhou XH

更新日期：2014-05-27 00:00:00

abstract：BACKGROUND:In the last decade, several epidemiological studies have demonstrated the potential of using seroprevalence (SP) and seroconversion rate (SCR) as informative indicators of malaria burden in low transmission settings or in populations on the cusp of elimination. However, most of studies are designed to contro...

journal_title：Malaria journal

authors： Sepúlveda N,Drakeley C

更新日期：2015-04-03 00:00:00

abstract：BACKGROUND:The intraerythrocytic development cycle (IDC) of the rodent malaria Plasmodium chabaudi is coordinated with host circadian rhythms. When this coordination is disrupted, parasites suffer a 50% reduction in both asexual stages and sexual stage gametocytes over the acute phase of infection. Reduced gametocyte d...

journal_title：Malaria journal

authors： Westwood ML,O'Donnell AJ,Schneider P,Albery GF,Prior KF,Reece SE

更新日期：2020-01-14 00:00:00

abstract：:The National Vector Borne Disease Control Programme (NVBDCP) of the Ministry of Health, Government of India is reporting about 2 million parasite positive cases each year, although case incidence is 30-fold or more under-estimated. Forty five to fifty percent of Plasmodium infections are caused by Plasmodium falciparu...

journal_title：Malaria journal

authors： Sharma VP

更新日期：2007-08-07 00:00:00

abstract：BACKGROUND:Malaria treatment policy recommends regular monitoring of drug utilization to generate information for ensuring effective use of anti-malarial drugs in Nigeria. This information is currently limited in the retail sector which constitutes a major source of malaria treatment in Nigeria, but are characterized b...

journal_title：Malaria journal

authors： Ezenduka CC,Ogbonna BO,Ekwunife OI,Okonta MJ,Esimone CO

更新日期：2014-06-24 00:00:00

abstract：BACKGROUND:Rosette-formation of Plasmodium falciparum parasitized erythrocytes is of importance in the development of severe malaria. The parasite-derived molecule PfEMP1 (Plasmodium falciparum erythrocyte membrane protein 1), central to rosetting, is suggested to be included in a multimeric vaccine targeting severe di...

journal_title：Malaria journal

authors： Angeletti D,Albrecht L,Wahlgren M,Moll K

更新日期：2013-01-24 00:00:00