Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-alpha and angiotensin II.

abstract：BACKGROUND:A recent study has shown that the implantable atrial defibrillator can restore sinus rhythm in patients with recurrent atrial fibrillation when therapy was delivered under physician observation. The objective of this study was to evaluate the safety and efficacy of ambulatory use of the implantable atrial de...

journal_title：Circulation

authors： Daoud EG,Timmermans C,Fellows C,Hoyt R,Lemery R,Dawson K,Ayers GM

更新日期：2000-09-19 00:00:00

abstract：BACKGROUND:Retinol-binding protein 4 (RBP4) may play an important role in the origin of insulin resistance and metabolic syndrome. Few prospective data are available on the relationship between RBP4 and coronary heart disease (CHD). Furthermore, previous studies did not distinguish among full-length and truncated forms...

journal_title：Circulation

authors： Sun Q,Kiernan UA,Shi L,Phillips DA,Kahn BB,Hu FB,Manson JE,Albert CM,Rexrode KM

更新日期：2013-05-14 00:00:00

abstract：:The effect of potassium ion (K+) depletion on postmyocardial infarction ventricular arrhythmias was investigated in 32 dogs: 12 control animals, 10 animals that ate a diet extremely low in K+ for 15 days, and 10 others that, in addition to dietary K+ deprivation, received 50 mg of hydrochlorothiazide four times. The e...

journal_title：Circulation

authors： Garan H,McGovern BA,Canzanello VJ,McCauley J,Bodvarsson M,Harrington JT,Madias NE,Newell JB,Ruskin JN

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:The overall performance of available mechanical intravascular ultrasound catheters for fetal transesophageal echocardiography during fetoscopic fetal cardiac interventions in sheep has been limited by radioelectronic interference, low system frame rates, and low acoustic outputs. Therefore, a more reliable d...

journal_title：Circulation

authors： Kohl T,Westphal M,Strümper D,Achenbach S,Halimeh S,Petry P,Aryee S,Buller T,Aleksiene R,Asfour B,Witteler R,Vogt J,Van Aken H,Scheld HH

更新日期：2001-10-09 00:00:00

abstract：BACKGROUND:Endothelial dysfunction of coronary arteries with impaired vasodilation has been reported in patients with arterial hypertension. However, the effect of dynamic exercise on coronary vasomotion of a stenotic vessel segment before and after PTCA has not yet been evaluated in these patients. METHODS AND RESULT...

journal_title：Circulation

authors： Frielingsdorf J,Kaufmann P,Suter T,Hug R,Hess OM

更新日期：1998-09-22 00:00:00

abstract：BACKGROUND:Drug-eluting stents have shown promising antirestenotic effects in clinical trials. Non-stent-based local delivery of antiproliferative drugs may offer additional flexibility and also reach vessel areas beyond the immediate stent coverage. The aim of the present study was to evaluate a novel method of local ...

journal_title：Circulation

authors： Scheller B,Speck U,Abramjuk C,Bernhardt U,Böhm M,Nickenig G

更新日期：2004-08-17 00:00:00

abstract：BACKGROUND:In recent decades, the rates of incident acute myocardial infarction (AMI) have declined in the United States, yet disparities by sex remain. In an integrated healthcare delivery system, we examined temporal trends in incident AMI among women and men. METHODS:We identified hospitalized AMI among members ≥35...

journal_title：Circulation

authors： Mefford MT,Li BH,Qian L,Reading SR,Harrison TN,Scott RD,Cavendish JJ,Jacobsen SJ,Kanter MH,Woodward M,Reynolds K

更新日期：2020-02-18 00:00:00

abstract：BACKGROUND:By the formation of cGMP, nitric oxide (NO)-sensitive guanylyl cyclase (GC) acts as the effector for the signaling molecule NO and mediates the relaxation of vascular smooth muscle and the inhibition of platelet aggregation. The compounds YC-1 and BAY 41-2272 are regarded as NO-independent activators and sen...

journal_title：Circulation

authors： Mullershausen F,Russwurm M,Friebe A,Koesling D

更新日期：2004-04-13 00:00:00

abstract：BACKGROUND:Imaging of the flow convergence region (FCR) proximal to a regurgitant orifice has been shown to provide a method for quantifying the regurgitant flow rate. According to the continuity principle, the FCR is constituted by concentric hemispheric isovelocity surfaces centered at the orifice. The flow rate is c...

journal_title：Circulation

authors： Bargiggia GS,Tronconi L,Sahn DJ,Recusani F,Raisaro A,De Servi S,Valdes-Cruz LM,Montemartini C

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:The balance between apoptosis and proliferation of vascular smooth muscle cells (VSMCs) is believed to contribute to the vascular remodeling process. Cyclic AMP response element-binding protein (CREB) is a critical transcription factor for the survival of neuronal cells and T lymphocytes. However, the role o...

journal_title：Circulation

authors： Tokunou T,Shibata R,Kai H,Ichiki T,Morisaki T,Fukuyama K,Ono H,Iino N,Masuda S,Shimokawa H,Egashira K,Imaizumi T,Takeshita A

更新日期：2003-09-09 00:00:00

abstract：BACKGROUND:Lifetime risk for atherosclerotic cardiovascular disease (CVD) has not previously been estimated, and the effect of risk factor burden on lifetime risk is unknown. METHODS AND RESULTS:We included all Framingham Heart Study participants who were free of CVD (myocardial infarction, coronary insufficiency, ang...

journal_title：Circulation

authors： Lloyd-Jones DM,Leip EP,Larson MG,D'Agostino RB,Beiser A,Wilson PW,Wolf PA,Levy D

更新日期：2006-02-14 00:00:00

abstract：BACKGROUND:In the past few years, although significant efforts have been made to assess flow distribution during retrograde cerebral perfusion with microspheres, dye, or hydrogen clearance, flow distribution in real time is still undefined. We used MR perfusion imaging to monitor flow distribution in the brain during a...

journal_title：Circulation

authors： Ye J,Ryner LN,Kozlowski P,Yang L,Del Bigio MR,Sun J,Donnelly M,Summers R,Salerno TA,Somorjai RL,Saunders JK,Deslauriers R

更新日期：1998-11-10 00:00:00

abstract：BACKGROUND:Coronary artery disease is the major cause of late cardiac allograft failure. However, few data exist regarding the natural history of changes in intimal and external elastic membrane (EEM) areas after heart transplantation. METHODS AND RESULTS:In 38 transplant recipients, serial intravascular ultrasound ex...

journal_title：Circulation

authors： Tsutsui H,Ziada KM,Schoenhagen P,Iyisoy A,Magyar WA,Crowe TD,Klingensmith JD,Vince DG,Rincon G,Hobbs RE,Yamagishi M,Nissen SE,Tuzcu EM

更新日期：2001-08-07 00:00:00

abstract：:A transient form of hypertrophic cardiomyopathy has been previously described in infants of diabetic mothers (IDMs). The purpose of this study was to determine the incidence, natural history and pathologic features of this cardiomyopathy in symptomatic and asymptomatic IDMs. We studied 47 IDMs for evidence of cardiomy...

journal_title：Circulation

authors： Gutgesell HP,Speer ME,Rosenberg HS

更新日期：1980-02-01 00:00:00

abstract：BACKGROUND:Enteroviruses (EVs) and adenoviruses (ADVs) have been considered common causes of myocarditis and dilated cardiomyopathy. In the present study, we report on the association of parvovirus B19 (PVB19) genomes in the clinical setting of acute myocarditis. METHODS AND RESULTS:This study included 24 consecutive ...

journal_title：Circulation

authors： Kühl U,Pauschinger M,Bock T,Klingel K,Schwimmbeck CP,Seeberg B,Krautwurm L,Poller W,Schultheiss HP,Kandolf R

更新日期：2003-08-26 00:00:00

abstract：BACKGROUND:Previous studies have shown that thrombin is a potent though slow-acting mitogen for vascular smooth muscle cells (SMC). Because thrombin generation in vivo is accompanied by platelet activation, it has been suggested that platelet-derived factors might enhance thrombin-induced SMC proliferation. No informat...

journal_title：Circulation

authors： Zucker TP,Bönisch D,Muck S,Weber AA,Bretschneider E,Glusa E,Schrör K

更新日期：1998-02-17 00:00:00

abstract：BACKGROUND:Clinical studies have demonstrated the efficacy of intravenous administration of agents that block platelet glycoprotein IIb/IIIa receptors in the setting of percutaneous coronary revascularization. Although the optimal duration of treatment has not been determined, more prolonged receptor blockade has been ...

journal_title：Circulation

authors： Simpfendorfer C,Kottke-Marchant K,Lowrie M,Anders RJ,Burns DM,Miller DP,Cove CS,DeFranco AC,Ellis SG,Moliterno DJ,Raymond RE,Sutton JM,Topol EJ

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:The role of infections and inflammation in the pathophysiology of coronary heart disease is emerging. We studied the independent and joint effects of these 2 components on coronary risk. METHODS AND RESULTS:We measured baseline levels of C-reactive protein (CRP) and antibodies to adenovirus, enterovirus, cy...

journal_title：Circulation

authors： Roivainen M,Viik-Kajander M,Palosuo T,Toivanen P,Leinonen M,Saikku P,Tenkanen L,Manninen V,Hovi T,Mänttäri M

更新日期：2000-01-25 00:00:00

abstract：:Successful long-term myocardial preservation is dependent on optimizing conditions during arrest, storage, and reperfusion. Neonatal piglet hearts were arrested and stored in University of Wisconsin solution (UW) at 4 degrees C for 24 hours and reperfused on a blood-perfused, adult animal-supported isolated circuit. R...

journal_title：Circulation

authors： Stein DG,Permut LC,Drinkwater DC Jr,Bhuta S,Chang P,Wu A,Laks H

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:In vivo gene transfer into injured arteries may provide a new means to facilitate molecular understanding of and to treat the intractable fibroproliferative arterial diseases. Selection of an optimal molecule to be transferred will be a key to successful gene therapy in the future. We tested the hypothesis t...

journal_title：Circulation

authors： Ueno H,Haruno A,Morisaki N,Furuya M,Kangawa K,Takeshita A,Saito Y

更新日期：1997-10-07 00:00:00

abstract：BACKGROUND:The present study investigated whether the ACAT inhibitor avasimibe can reduce atherogenesis independently of its cholesterol-lowering effect in ApoE*3-Leiden mice. METHODS AND RESULTS:Two groups of 15 female ApoE*3-Leiden mice were put on a high-cholesterol (HC) diet; 1 group received 0.01% (wt/wt) avasimi...

journal_title：Circulation

authors： Delsing DJ,Offerman EH,van Duyvenvoorde W,van Der Boom H,de Wit EC,Gijbels MJ,van Der Laarse A,Jukema JW,Havekes LM,Princen HM

更新日期：2001-04-03 00:00:00

abstract：BACKGROUND:Plaque rupture with subsequent thrombosis is recognized as the underlying pathophysiology of most acute coronary syndromes and stroke. Thus, direct thrombus visualization may be beneficial for both diagnosis and guidance of therapy. We sought to test the feasibility of direct imaging of acute and subacute th...

journal_title：Circulation

authors： Botnar RM,Perez AS,Witte S,Wiethoff AJ,Laredo J,Hamilton J,Quist W,Parsons EC Jr,Vaidya A,Kolodziej A,Barrett JA,Graham PB,Weisskoff RM,Manning WJ,Johnstone MT

更新日期：2004-04-27 00:00:00

abstract：:One hundred consecutive men with a normal ECG at rest had a maximal treadmill test using 14 leads during and post-exercise. Coronary arteriography performed the following day revealed coronary stenoses greater than or equal to 70% in 66 patients. Test results obtained from a V5 lead were compared to different lead com...

journal_title：Circulation

authors： Chaitman BR,Bourassa MG,Wagniart P,Corbara F,Ferguson RJ

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Recently, it was reported that the degree of microvascular injury and left ventricular functional recovery during the chronic period can be predicted after treatment of the infarct-related artery based on the coronary flow velocity (CFV) pattern assessed using a Doppler guidewire. The aim of this prospective...

journal_title：Circulation

authors： Yamamuro A,Akasaka T,Tamita K,Yamabe K,Katayama M,Takagi T,Morioka S

更新日期：2002-12-10 00:00:00

abstract：:Although coronary thrombus overlying a disrupted atherosclerotic plaque has long been considered the hallmark and the primary therapeutic target for acute myocardial infarction (MI), multiple other mechanisms are now known to cause or contribute to MI. It is further recognized that an MI is just one of many types of a...

journal_title：Circulation

authors： DeFilippis AP,Chapman AR,Mills NL,de Lemos JA,Arbab-Zadeh A,Newby LK,Morrow DA

更新日期：2019-11-12 00:00:00

abstract：:Since platelet accumulation may be an important determinant of restenosis after angioplasty, the time course of 51Cr-labeled platelet accumulation after experimental angioplasty was evaluated in a deendothelialized, hypercholesterolemic rabbit preparation of atherosclerosis. Marked platelet accumulation (39.5 +/- 8.7 ...

journal_title：Circulation

authors： Wilentz JR,Sanborn TA,Haudenschild CC,Valeri CR,Ryan TJ,Faxon DP

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:Theoretically, the efficacy of continuous warm blood cardioplegia may be improved when administered retrogradely (RCWBC) rather than antegradely (ACWBC) in the setting of acute regional ischemia because of enhanced oxygen and substrate delivery to myocardial tissue distal to an acute coronary artery occlusio...

journal_title：Circulation

authors： Misare BD,Krukenkamp IB,Lazer ZP,Levitsky S

更新日期：1992-11-01 00:00:00

abstract：:Twelve consecutive patients who developed torsade de pointes (polymorphous ventricular tachycardia with marked QT prolongation, TdP) over a 4 year period were treated with intravenous injections of magnesium sulfate. In nine of the patients a single bolus of 2 g completely abolished the TdP within 1 to 5 min, and in t...

journal_title：Circulation

authors： Tzivoni D,Banai S,Schuger C,Benhorin J,Keren A,Gottlieb S,Stern S

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Cyclooxygenase (COX)-2 contributes to vascular smooth muscle cell (VSMC) proliferation induced by tumor necrosis factor (TNF) and angiotensin II. The present study demonstrates, however, that depending on prevailing conditions, COX-2-derived prostanoids may also inhibit VSMC proliferation. METHODS AND RESUL...

journal_title：Circulation

authors： Haider A,Lee I,Grabarek J,Darzynkiewicz Z,Ferreri NR

更新日期：2003-08-26 00:00:00

abstract：BACKGROUND:Growth factors such as platelet-derived growth factor (PDGF) have been postulated to be important mediators of neointimal formation in balloon-injured artery. Binding of growth factors to their receptors activates intrinsic receptor tyrosine kinase, resulting in tyrosine phosphorylation of receptors themselv...

journal_title：Circulation

authors： Abe J,Deguchi J,Matsumoto T,Takuwa N,Noda M,Ohno M,Makuuchi M,Kurokawa K,Takuwa Y

更新日期：1997-09-16 00:00:00