Percutaneous transluminal coronary angioplasty reverses vasoconstriction of stenotic coronary arteries in hypertensive patients.

abstract：:Fifty-six patients undergoing orthotopic cardiac transplantation were given Minnesota ALG prophylactically or therapeutically for acute cardiac rejection. During a follow-up period of 0-28 months (mean follow-up period, 11.9 months), the actuarial survival for the entire group was 96% and 86% at 30 days and 1 year, re...

journal_title：Circulation

authors： Keith FM,Magilligan DJ Jr,Lakier JB,Drost CJ

更新日期：1988-11-01 00:00:00

abstract：:Over the last 20 years, operative mortality has decreased and late survival has improved for patients with chronic stable angina who have coronary artery bypass surgery. However, this favorable trend may not continue because the operation is now extended to elderly and high-risk patients. The most powerful predictors ...

journal_title：Circulation

authors： Gersh BJ,Califf RM,Loop FD,Akins CW,Pryor DB,Takaro TC

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Chronic heart failure is associated with endothelial dysfunction including impaired endothelium-mediated, flow-dependent dilation (FDD). Since endothelial function is thought to play an important role in coordinating tissue perfusion and modulating arterial compliance, interventions to improve endothelial dy...

journal_title：Circulation

authors： Hornig B,Maier V,Drexler H

更新日期：1996-01-15 00:00:00

abstract：:The first stage of a repair of pulmonary atresia with intact ventricular septum (type I) was attempted in a 2-day-old infant. At surgery, decompression of the hypertensive small right ventricle was followed by a sudden loss of myocardial contractility and death. Postmortem examination revealed a fistula with a large o...

journal_title：Circulation

authors： O'Connor WN,Cottrill CM,Johnson GL,Noonan JA,Todd EP

更新日期：1982-04-01 00:00:00

abstract：:Correlates of high-density lipoprotein (HDL) cholesterol levels were studied in 4756 white males and females ages 20-59 years examined during a population survey conducted by 10 North American Lipid Research Clinics. Multivariable analysis was used to assess the relation of social, demographic, physical and behavioral...

journal_title：Circulation

authors： Heiss G,Johnson NJ,Reiland S,Davis CE,Tyroler HA

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:Minimally invasive coronary artery bypass grafting (MICS CABG) is a novel coronary operation that does not require infrastructure and is potentially available to all cardiac surgeons. It aims at decreasing the invasiveness of conventional CABG while preserving the applicability and durability of surgical rev...

journal_title：Circulation

authors： McGinn JT Jr,Usman S,Lapierre H,Pothula VR,Mesana TG,Ruel M

更新日期：2009-09-15 00:00:00

abstract：BACKGROUND:Inbred mouse strains C57BL/6J (B6) and C3H/HeJ (C3H) exhibit marked differences in atherosclerosis susceptibility. We sought to determine whether the difference in atherosclerosis susceptibility resides at the level of arterial walls. METHODS AND RESULTS:Thoracic aortic segments from 8-week-old female B6 an...

journal_title：Circulation

authors： Pei H,Wang Y,Miyoshi T,Zhang Z,Matsumoto AH,Helm GA,Tellides G,Shi W

更新日期：2006-11-28 00:00:00

abstract：BACKGROUND:Recent studies suggest that the oxygen-sensing pathway consisting of transcription factor hypoxia-inducible factor and prolyl hydroxylase domain proteins (PHDs) plays a critical role in glucose metabolism. However, the role of adipocyte PHD in the development of obesity has not been clarified. We examined wh...

journal_title：Circulation

authors： Matsuura H,Ichiki T,Inoue E,Nomura M,Miyazaki R,Hashimoto T,Ikeda J,Takayanagi R,Fong GH,Sunagawa K

更新日期：2013-05-28 00:00:00

abstract：BACKGROUND:Several methods exist by which to assess type A behavior (TAB). Although the videotaped clinical interview is regarded as the "gold standard," self-report measures have also proved useful in assessing TAB in large population studies. The purpose of this study was to examine prospectively the relationship of ...

journal_title：Circulation

authors： Kawachi I,Sparrow D,Kubzansky LD,Spiro A 3rd,Vokonas PS,Weiss ST

更新日期：1998-08-04 00:00:00

abstract：BACKGROUND:In our multicenter study of the total cavopulmonary connection (TCPC), a cohort of patients with long-segment left pulmonary artery (LPA) stenosis was observed (35%). The clinically recognized detrimental effects of LPA stenosis motivated a computational fluid dynamic simulation study within 3-dimensional pa...

journal_title：Circulation

authors： Pekkan K,Kitajima HD,de Zelicourt D,Forbess JM,Parks WJ,Fogel MA,Sharma S,Kanter KR,Frakes D,Yoganathan AP

更新日期：2005-11-22 00:00:00

abstract：:Vigorous hyperventilation was induced for five minutes immediately after a five-minute infusion of 100 ml of Tris-buffer (pH 10) in nine patients with Prinzmetal's variant angina. In eight of the patients, chest pain with ischemic changes in the electrocardiogram occurred during this procedure or within five minutes a...

journal_title：Circulation

authors： Yasue H,Nagao M,Omote S,Takizawa A,Miwa K,Tanaka S

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND:Although early trials indicate the treatment of restenosis with radiation therapy is safe and effective, the long-term impact of this new technology has been questioned. The possibility of late untoward consequences, such as aneurysm formation, perforation, and accelerated vascular disease, is of significant...

journal_title：Circulation

authors： Teirstein PS,Massullo V,Jani S,Russo RJ,Cloutier DA,Schatz RA,Guarneri EM,Steuterman S,Sirkin K,Norman S,Tripuraneni P

更新日期：1999-01-19 00:00:00

abstract：BACKGROUND:Coronary heart disease (CHD) represents the largest share of cardiovascular disease in the United States, but there are conspicuous discrepancies between CHD and total cardiovascular death rates across the states, possibly due in part to variations in physician assignment of causes of death. Our aim was to i...

journal_title：Circulation

authors： Murray CJ,Kulkarni SC,Ezzati M

更新日期：2006-05-02 00:00:00

abstract：:Aortic root motion was studied in 24 normal volunteers at rest and during the Valsalva maneuver, isometric exercise, and amyl nitrite inhalation. In addition root motion was correlated with the stroke volumes determined at cardiac catheterization in 24 patients. The root has distinct systolic movement, the amplitude a...

journal_title：Circulation

authors： Pratt RC,Parisi AF,Harrington JJ,Sasahara AA

更新日期：1976-06-01 00:00:00

abstract：BACKGROUND:Alterations in myocardial function and systemic vascular tone are well documented in congestive heart failure (CHF), but little information is available on the effects of CHF on pulmonary vessels. We examined the mechanisms of tone regulation of canine pulmonary arteries during pacing-induced CHF. METHODS A...

journal_title：Circulation

authors： Mathew R,Wang J,Gewitz MH,Hintze TH,Wolin MS

更新日期：1993-05-01 00:00:00

abstract：:Mitral valve closure during cardiopulmonary resuscitation may result from direct cardiac compression. An alternative hypothesis is that with a rise in intrathoracic pressure, mitral valve closure can occur but may be influenced by whether the lungs are inflated or deflated. To test this hypothesis, we placed a large-b...

journal_title：Circulation

authors： Halperin HR,Weiss JL,Guerci AD,Chandra N,Tsitlik JE,Brower R,Beattie C,Wurmb E,Cadden J,Weisfeldt ML

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:An association of chronic Chlamydia pneumoniae infection to coronary heart disease has been suggested recently. In a recent study, we demonstrated circulating immune complexes containing chlamydial genus-specific lipopolysaccharide in patients with coronary heart disease. The objective of the present study w...

journal_title：Circulation

authors： Linnanmäki E,Leinonen M,Mattila K,Nieminen MS,Valtonen V,Saikku P

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:High blood pressure (BP) continues to be a major, poorly controlled but modifiable risk factor for cardiovascular death. Among key Western lifestyle factors, a diet poor in fiber is associated with prevalence of high BP. The impact of lack of prebiotic fiber and the associated mechanisms that lead to higher ...

journal_title：Circulation

authors： Kaye DM,Shihata WA,Jama HA,Tsyganov K,Ziemann M,Kiriazis H,Horlock D,Vijay A,Giam B,Vinh A,Johnson C,Fiedler A,Donner D,Snelson M,Coughlan MT,Phillips S,Du XJ,El-Osta A,Drummond G,Lambert GW,Spector TD,Valdes AM

更新日期：2020-04-28 00:00:00

abstract：:We evaluated the accuracy of the recently reported technique of estimating intraventricular volume by measurement of intracavitary electrical conductance in six isolated, ejecting, canine left ventricles. Left ventricular volumes were measured directly by a previously validated servosystem that employed an electrocond...

journal_title：Circulation

authors： Burkhoff D,van der Velde E,Kass D,Baan J,Maughan WL,Sagawa K

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:Angiogenesis is a critical feature of plaque development in atherosclerosis and might play a key role in both the initiation and later rupture of plaques that lead to myocardial infarction and stroke. The precursory molecular or cellular events that initiate plaque growth and that ultimately contribute to pl...

journal_title：Circulation

authors： Winter PM,Morawski AM,Caruthers SD,Fuhrhop RW,Zhang H,Williams TA,Allen JS,Lacy EK,Robertson JD,Lanza GM,Wickline SA

更新日期：2003-11-04 00:00:00

abstract：BACKGROUND:Carotid artery stenting (CAS) has recently emerged as a potential alternative to carotid endarterectomy. Cerebral embolization is the most devastating complication of CAS, and the echogenicity of carotid plaque has been indicated as one of the risk factors involved. This is the first study to analyze the rol...

journal_title：Circulation

authors： Biasi GM,Froio A,Diethrich EB,Deleo G,Galimberti S,Mingazzini P,Nicolaides AN,Griffin M,Raithel D,Reid DB,Valsecchi MG

更新日期：2004-08-10 00:00:00

abstract：:To examine the effects of propranolol and nifedipine on exercise-induced attack in patients with variant angina, exercise 201Tl myocardial scintigraphy with quantitative analysis by emission-computed tomography was performed in 20 patients with variant angina after oral propranolol (80 mg), nifedipine (20 mg), and pla...

journal_title：Circulation

authors： Kugiyama K,Yasue H,Horio Y,Morikami Y,Fujii H,Koga Y,Kojima A,Takahashi M

更新日期：1986-08-01 00:00:00

abstract：:To assess the likelihood of procedural success in patients with multivessel coronary disease undergoing percutaneous coronary angioplasty, 350 consecutive patients (1,100 stenoses) from four clinical sites were evaluated. Eighteen variables characterizing the severity and morphology of each stenosis and 18 patient-rel...

journal_title：Circulation

authors： Ellis SG,Vandormael MG,Cowley MJ,DiSciascio G,Deligonul U,Topol EJ,Bulle TM

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:MicroRNAs (miRs) participate in many cardiac pathophysiological processes, including ischemia/reperfusion (I/R)-induced cardiac injury. Recently, we and others observed that miR-494 was downregulated in murine I/R-injured and human infarcted hearts. However, the functional consequence of miR-494 in response ...

journal_title：Circulation

authors： Wang X,Zhang X,Ren XP,Chen J,Liu H,Yang J,Medvedovic M,Hu Z,Fan GC

更新日期：2010-09-28 00:00:00

abstract：BACKGROUND:Vascular smooth muscle cell growth factors are postulated to contribute to cardiac allograft vasculopathy (CAV). Few data quantitatively address the timing, location, or stimuli for growth factor expression and relationship to CAV. METHODS AND RESULTS:Acidic fibroblast growth factor (aFGF) mRNA expression w...

journal_title：Circulation

authors： Miller GG,Davis SF,Atkinson JB,Chomsky DB,Pedroso P,Reddy VS,Drinkwater DC,Zhao XM,Pierson RN

更新日期：1999-12-14 00:00:00

abstract：BACKGROUND:Both thallium imaging and low-dose dobutamine echocardiography have been proposed to predict the reversibility of left ventricular (LV) dysfunction in patients with coronary disease. The present study was designed to evaluate whether the use of these techniques during the preoperative assessment of coronary ...

journal_title：Circulation

authors： Vanoverschelde JL,Gerber BL,D'Hondt AM,De Kock M,Dion R,Wijns W,Melin JA

更新日期：1995-11-01 00:00:00

abstract：:Frank lead vectorcardiograms (VCG) from four carefully selected patient subgroups (226 patients) were analyzed to develop optimal criteria for the diagnosis of anterior myocardial infarction. Specificity was evaluated using 100 healthy volunteers under age 30 and 80 patients with normal left ventriculogram and normal ...

journal_title：Circulation

authors： Starr JW,Wagner GS,Draffin RM,Reed JB,Walston A 2nd,Behar VS

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:Clinical studies have demonstrated the efficacy of intravenous administration of agents that block platelet glycoprotein IIb/IIIa receptors in the setting of percutaneous coronary revascularization. Although the optimal duration of treatment has not been determined, more prolonged receptor blockade has been ...

journal_title：Circulation

authors： Simpfendorfer C,Kottke-Marchant K,Lowrie M,Anders RJ,Burns DM,Miller DP,Cove CS,DeFranco AC,Ellis SG,Moliterno DJ,Raymond RE,Sutton JM,Topol EJ

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Atherosclerosis is a multifactorial disease in which inflammatory processes play an important role. Inflammation underlies lesion evolution at all stages, from establishment to plaque rupture and thrombosis. Costimulatory molecules of the tumor necrosis factor superfamily such as CD40/CD40L and OX40/OX40L ha...

journal_title：Circulation

authors： Olofsson PS,Söderström LA,Wågsäter D,Sheikine Y,Ocaya P,Lang F,Rabu C,Chen L,Rudling M,Aukrust P,Hedin U,Paulsson-Berne G,Sirsjö A,Hansson GK

更新日期：2008-03-11 00:00:00

abstract：BACKGROUND:Smooth muscle cell (SMC) migration and proliferation critically influence the clinical course of vascular disease. We tested the effect of the novel small leucine-rich repeat protein podocan on SMC migration and proliferation using a podocan-deficient mouse in combination with a model of arterial injury and ...

journal_title：Circulation

authors： Hutter R,Huang L,Speidl WS,Giannarelli C,Trubin P,Bauriedel G,Klotman ME,Fuster V,Badimon JJ,Klotman PE

更新日期：2013-11-26 00:00:00