Effects of propranolol and nifedipine on exercise-induced attack in patients variant angina: assessment by exercise thallium-201 myocardial scintigraphy with quantitative rotational tomography.

abstract：:Statins (HMG-CoA reductase inhibitors) are used widely for the treatment of hypercholesterolemia. They inhibit HMG-CoA reductase competitively, reduce LDL levels more than other cholesterol-lowering drugs, and lower triglyceride levels in hypertriglyceridemic patients. Statins are well tolerated and have an excellent ...

journal_title：Circulation

authors： Maron DJ,Fazio S,Linton MF

更新日期：2000-01-18 00:00:00

abstract：BACKGROUND:We evaluated the prognosis of deferred and revascularized coronary stenoses after fractional flow reserve (FFR) measurement to assess its revascularization threshold in clinical practice. METHODS:The IRIS-FFR registry (Interventional Cardiology Research In-cooperation Society Fractional Flow Reserve) prospe...

journal_title：Circulation

authors： Ahn JM,Park DW,Shin ES,Koo BK,Nam CW,Doh JH,Kim JH,Chae IH,Yoon JH,Her SH,Seung KB,Chung WY,Yoo SY,Lee JB,Choi SW,Park K,Hong TJ,Lee SY,Han M,Lee PH,Kang SJ,Lee SW,Kim YH,Lee CW,Park SW,Park SJ,IRIS-FF

更新日期：2017-06-06 00:00:00

abstract：BACKGROUND:The identification of high-risk patients who require early revascularization has become increasingly important with the present emphasis on reducing health care resources. This is particularly relevant to health care systems with prolonged waiting times for interventions. Myocardial viability imaging with th...

journal_title：Circulation

authors： Beanlands RS,Hendry PJ,Masters RG,deKemp RA,Woodend K,Ruddy TD

更新日期：1998-11-10 00:00:00

abstract：BACKGROUND:Paraplegia remains a devastating complication of thoracic aortic surgery. The mechanism of the antecedent spinal cord ischemia and reperfusion injury (IR) remains poorly described. IR involves 2 injuries, an initial ischemic insult and subsequent inflammatory amplification of the injury. This mechanism is co...

journal_title：Circulation

authors： Smith PD,Puskas F,Meng X,Lee JH,Cleveland JC Jr,Weyant MJ,Fullerton DA,Reece TB

更新日期：2012-09-11 00:00:00

abstract：BACKGROUND:Elevated lipoprotein (Lp) (a) concentrations are associated with coronary artery disease and myocardial infarction. Lp(a) is structurally related to proteins involved in lipid transport, fibrinolysis, coagulation, and cellular mitogenesis and is known to have important physiological interactions with the coa...

journal_title：Circulation

authors： Desmarais RL,Sarembock IJ,Ayers CR,Vernon SM,Powers ER,Gimple LW

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Oral anticoagulation (OAC) therapy is effective in atrial fibrillation but requires vigilance to maintain the international normalized ratio in the therapeutic range. This report examines how differences in time in therapeutic range (TTR) between centers and between countries affect the outcomes of OAC thera...

journal_title：Circulation

authors： Connolly SJ,Pogue J,Eikelboom J,Flaker G,Commerford P,Franzosi MG,Healey JS,Yusuf S,ACTIVE W Investigators.

更新日期：2008-11-11 00:00:00

abstract：:We have compared casual indirect measurements of arterial pressure obtained 1) by the general practitioner (GP) and 2) in the outpatient clinic (OPC) with 24 hour continuous recording of direct arterial pressure in two selected group of unrestricted patients. 1) Eight asymptomatic, untreated patients with suspected hy...

journal_title：Circulation

authors： Littler WA,Honour AJ,Pugsley DJ,Sleight P

更新日期：1975-06-01 00:00:00

abstract：BACKGROUND:Despite the fact that nonsteroidal anti-inflammatory drugs (NSAIDs) are contraindicated among patients with established cardiovascular disease, many receive NSAID treatment for a short period of time. However, little is known about the association between NSAID treatment duration and risk of cardiovascular d...

journal_title：Circulation

authors： Schjerning Olsen AM,Fosbøl EL,Lindhardsen J,Folke F,Charlot M,Selmer C,Lamberts M,Bjerring Olesen J,Køber L,Hansen PR,Torp-Pedersen C,Gislason GH

更新日期：2011-05-24 00:00:00

abstract：BACKGROUND:The use of bipolar endocardial electrogram characteristics to guide radiofrequency (RF) current catheter ablation of accessory pathways (APs) has been advocated by several investigators. However, the influences of a varying anatomy of the AP and the atrioventricular groove, of different ablative approaches, ...

journal_title：Circulation

authors： Cappato R,Schlüter M,Mont L,Kuck KH

更新日期：1994-08-01 00:00:00

abstract：:All physicians increasingly will encounter patients who have implanted cardioverter-defibrillators (ICDs) for protection from ventricular arrhythmias. This advisory provides a concise summary relevant to the assessment and management of patients with ICDs, including those who present to primary care or emergency depar...

journal_title：Circulation

authors： Stevenson WG,Chaitman BR,Ellenbogen KA,Epstein AE,Gross WL,Hayes DL,Strickberger SA,Sweeney MO,Subcommittee on Electrocardiography and Arrhythmias of the American Heart Association Council on Clinical Cardiology.,Heart Rhythm Society.

更新日期：2004-12-21 00:00:00

abstract：BACKGROUND:A completed Fontan circulation is the goal in the management of patients with single-ventricle physiology. To achieve this end, a two-stage rather than a single-stage approach is carried out routinely at many centers. Some groups have advocated baffle fenestration for virtually all patients to minimize post-...

journal_title：Circulation

authors： Hsu DT,Quaegebeur JM,Ing FF,Selber EJ,Lamour JM,Gersony WM

更新日期：1997-11-04 00:00:00

abstract：BACKGROUND:Age is a predictor of cognitive dysfunction after cardiac surgery, but the mechanism is unknown. The purpose of our study was to determine whether age-related decrements in cognition are associated with cerebral blood flow (CBF) autoregulation during cardiopulmonary bypass (CPB). METHODS AND RESULTS:Cogniti...

journal_title：Circulation

authors： Newman MF,Croughwell ND,Blumenthal JA,White WD,Lewis JB,Smith LR,Frasco P,Towner EA,Schell RM,Hurwitz BJ

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:The time constant of truncated exponential pulses used with implantable defibrillators is determined by the output capacitor size and defibrillation pathway resistance. The optimal capacitor size is unknown. METHODS AND RESULTS:This study compared defibrillation threshold (DFT) for standard 120-microF capac...

journal_title：Circulation

authors： Swerdlow CD,Kass RM,Chen PS,Hwang C,Raissi S

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used to treat cardiogenic shock. However, VA-ECMO might hamper myocardial recovery. The Impella unloads the left ventricle. This study aimed to evaluate whether left ventricular unloading in patients with cardiogenic shock treated wit...

journal_title：Circulation

authors： Schrage B,Becher PM,Bernhardt A,Bezerra H,Blankenberg S,Brunner S,Colson P,Cudemus Deseda G,Dabboura S,Eckner D,Eden M,Eitel I,Frank D,Frey N,Funamoto M,Goßling A,Graf T,Hagl C,Kirchhof P,Kupka D,Landmesser U,Li

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Orally administered heparin (OHEP) is unreliable because of poor absorption. Sodium N-(8[2-hydroxybenzoyl]amino) caprylate (SNAC) is an amido acid that facilitates the gastrointestinal absorption of heparin. We evaluated the effectiveness of OHEP combined with SNAC (OHEP/SNAC) in the treatment of deep-vein t...

journal_title：Circulation

authors： Gonze MD,Salartash K,Sternbergh WC 3rd,Baughman RA,Leone-Bay A,Money SR

更新日期：2000-06-06 00:00:00

abstract：BACKGROUND:Endocardial mapping of sustained arrhythmias has traditionally been performed with a roving diagnostic catheter. Although this approach is adequate for many tachyarrhythmias, it has limitations. The purpose of this study was to evaluate a novel noncontact mapping system for assessing atrial tachyarrhythmias....

journal_title：Circulation

authors： Kadish A,Hauck J,Pederson B,Beatty G,Gornick C

更新日期：1999-04-13 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) is frequently encountered in patients with heart failure (HF) and is also a predictor of morbidity and mortality in this population. Recent experimental studies have shown electrical and structural atrial remodeling with increased fibrosis in animals with HF and have suggested a prev...

journal_title：Circulation

authors： Vermes E,Tardif JC,Bourassa MG,Racine N,Levesque S,White M,Guerra PG,Ducharme A

更新日期：2003-06-17 00:00:00

abstract：:Although the postoperative hemodynamic and echocardiographic features of idiopathic hypertrophic subaortic stenosis have been studied, the expected consistent postoperative thinning of the interventricular septum has not been reported. In this study, the short-term effects of septal myectomy were evaluated in 16 patie...

journal_title：Circulation

authors： Schapira JN,Stemple DR,Martin RP,Rakowski H,Stinson EB,Popp RL

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND:Initially based on histology, the diagnosis of renal artery fibromuscular dysplasia (FMD) is now based mostly on angiographic appearance because arterial tissue samples are rarely available. This retrospective cross-sectional study aimed to assess the clinical relevance of a binary angiographic classificatio...

journal_title：Circulation

authors： Savard S,Steichen O,Azarine A,Azizi M,Jeunemaitre X,Plouin PF

更新日期：2012-12-18 00:00:00

abstract：BACKGROUND:Transcatheter aortic valve replacement (TAVR) represents a paradigm shift in the therapeutic options for patients with severe aortic stenosis. However, rapid and exponential growth in TAVR demand may overwhelm capacity, translating to inadequate access and prolonged wait times. Our objective was to evaluate ...

journal_title：Circulation

authors： Elbaz-Greener G,Masih S,Fang J,Ko DT,Lauck SB,Webb JG,Nallamothu BK,Wijeysundera HC

更新日期：2018-07-31 00:00:00

abstract：:We examined the temporal kinetics of onset and offset of the cardiac electrophysiologic effects of orally administered amiodarone in chronically instrumented, unsedated adult dogs (n = 8). Right atrial (RA), atrioventricular nodal (AVN), and right ventricular (RV) effective refractory period (ERP), and AVN functional ...

journal_title：Circulation

authors： Tuna IC,Qi AC,Gornick C,Bolman RM 3rd,Benditt DG

更新日期：1985-12-01 00:00:00

abstract：:Acute intravenous administration of the new beta 1-adrenergic receptor partial agonist xamoterol lowers left ventricular end-diastolic pressure and improves the isovolumic indexes of inotropic state and relaxation. To determine if these hemodynamic changes were maintained after prolonged administration, the dose-respo...

journal_title：Circulation

authors： Pouleur H,Etienne J,Van Mechelen H,Gurné O,Rousseau MF

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:The striated preferentially expressed gene (Speg) generates 4 different isoforms through alternative promoter use and tissue-specific splicing. Depending on the cell type, Speg isoforms may serve as markers of striated or smooth muscle differentiation. METHODS AND RESULTS:To elucidate function of Speg gene ...

journal_title：Circulation

authors： Liu X,Ramjiganesh T,Chen YH,Chung SW,Hall SR,Schissel SL,Padera RF Jr,Liao R,Ackerman KG,Kajstura J,Leri A,Anversa P,Yet SF,Layne MD,Perrella MA

更新日期：2009-01-20 00:00:00

abstract：BACKGROUND:Pulmonary veno-occlusive disease is caused by excessive cell proliferation and fibrosis, which obliterate the lumen of pulmonary venules, leading to pulmonary hypertension, right ventricular failure, and death. This condition has no effective treatment and a 5-year survival of <5%. Understanding the mechanis...

journal_title：Circulation

authors： Lathen C,Zhang Y,Chow J,Singh M,Lin G,Nigam V,Ashraf YA,Yuan JX,Robbins IM,Thistlethwaite PA

更新日期：2014-09-30 00:00:00

abstract：BACKGROUND:The goal of this study was to examine a possible association between systemic microinflammation, as reflected by C-reactive protein (CRP) serum levels, and coronary vasomotion in patients with coronary risk factors but with angiographically normal coronary arteries. METHODS AND RESULTS:Coronary vasomotor fu...

journal_title：Circulation

authors： Schindler TH,Nitzsche EU,Olschewski M,Magosaki N,Mix M,Prior JO,Facta AD,Solzbach U,Just H,Schelbert HR

更新日期：2004-08-31 00:00:00

abstract：BACKGROUND:Patients with heart failure and systolic dysfunction may develop disordered breathing during sleep. Repeated episodes of apnea and hypopnea may result in desaturation and arousals, which could adversely affect left ventricular function. The purpose of this study was to determine the short-term effects of con...

journal_title：Circulation

authors： Javaheri S

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Guidelines for the management of patients with suspected coronary artery disease (CAD) rely on the age, sex, and angina typicality-based pretest probabilities of angiographically significant CAD derived from invasive coronary angiography (guideline probabilities). Reliability of guideline probabilities has n...

journal_title：Circulation

authors： Cheng VY,Berman DS,Rozanski A,Dunning AM,Achenbach S,Al-Mallah M,Budoff MJ,Cademartiri F,Callister TQ,Chang HJ,Chinnaiyan K,Chow BJ,Delago A,Gomez M,Hadamitzky M,Hausleiter J,Karlsberg RP,Kaufmann P,Lin FY,Maffei E

更新日期：2011-11-29 00:00:00

abstract：BACKGROUND:The World Health Organization aims to reduce mortality from chronic diseases including cardiovascular disease (CVD) by 25% by 2025. High blood pressure is a leading CVD risk factor. We sought to compare 3 strategies for treating blood pressure in China and India: a treat-to-target (TTT) strategy emphasizing ...

journal_title：Circulation

authors： Basu S,Yudkin JS,Sussman JB,Millett C,Hayward RA

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Elevated levels of oxidized phospholipids (OxPLs) on apolipoprotein B-100 particles (OxPL/apoB) are associated with cardiovascular disease and predict new cardiovascular events. Elevated lipoprotein (a) [Lp(a)] levels are a risk factor for cardiovascular disease in whites and also in blacks if they carry sma...

journal_title：Circulation

authors： Tsimikas S,Clopton P,Brilakis ES,Marcovina SM,Khera A,Miller ER,de Lemos JA,Witztum JL

更新日期：2009-04-07 00:00:00

abstract：BACKGROUND:Human endothelial and vascular smooth muscle cells synthesize prostanoids. Several of these have been implicated in the physiological and pathophysiological regulation of vascular tone; however, there is no direct evidence that human blood vessels synthesize sufficient prostanoid to alter vessel tone. METHO...

journal_title：Circulation

authors： Bhagat K,Collier J,Vallance P

更新日期：1995-10-15 00:00:00