Physical training improves endothelial function in patients with chronic heart failure.

abstract：:Oral flecainide acetate was administered to 34 patients with documented symptomatic paroxysmal supraventricular tachycardia (PSVT) with a double-blind, placebo-controlled, 8-week crossover trial design. PSVT was defined as a regular tachycardia of at least 120 beats/min without evidence of atrioventricular dissociatio...

journal_title：Circulation

authors： Henthorn RW,Waldo AL,Anderson JL,Gilbert EM,Alpert BL,Bhandari AK,Hawkinson RW,Pritchett EL

更新日期：1991-01-01 00:00:00

abstract：:Between July 1985 and September 1987, 25 patients underwent 26 carotid endarterectomies based on an abnormal duplex scan (B-mode ultrasonography and pulsed-Doppler sound spectral analysis) indicative of severe stenosis or ulceration. Arteriography was not performed because of severe unstable angina requiring coronary ...

journal_title：Circulation

authors： Marshall WG Jr,Kouchoukos NT,Murphy SF,Pelate C

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:Activation of protein kinase C-linked receptors and subsequent opening of the mitochondrial ATP-sensitive K(+) (mitoK(ATP)) channel are crucial in preconditioning (PC). This study examined whether postinfarct ventricular remodeling interferes with the PC mechanism. METHODS AND RESULTS:Two weeks before isola...

journal_title：Circulation

authors： Miki T,Miura T,Tsuchida A,Nakano A,Hasegawa T,Fukuma T,Shimamoto K

更新日期：2000-07-25 00:00:00

abstract：:This article provides a selective overview of epidemiologic studies on the relationship between psychosocial factors and blood pressure elevation. The review focuses on English-language reports published since 1975 and emphasizes two broad areas of research: changes in mean blood pressures of third world populations u...

journal_title：Circulation

authors： James SA

更新日期：1987-07-01 00:00:00

abstract：:Continuous-wave Doppler echocardiography was used to estimate pulmonary artery pressures by measuring pulmonary regurgitant flow velocity in 21 patients with pulmonary hypertension (mean pulmonary artery pressure greater than or equal to 20 mm Hg) and 24 patients without pulmonary hypertension. The pulmonary regurgita...

journal_title：Circulation

authors： Masuyama T,Kodama K,Kitabatake A,Sato H,Nanto S,Inoue M

更新日期：1986-09-01 00:00:00

abstract：:Of 1,801 patients in the 1985-1986 Percutaneous Transluminal Coronary Angioplasty (PTCA) Registry, 122 (6.8%) had periprocedural occlusion (4.9% in the catheterization laboratory, 1.9% outside the laboratory). Baseline patient factors independently associated with increased occlusion rates included triple-vessel disea...

journal_title：Circulation

authors： Detre KM,Holmes DR Jr,Holubkov R,Cowley MJ,Bourassa MG,Faxon DP,Dorros GR,Bentivoglio LG,Kent KM,Myler RK

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:The coexistence of atrial fibrillation (AF) and atrial flutter (AFL) is well recognized. AF precedes the onset of AFL in almost all instances. We evaluated the effect of 2 ablation strategies in patients with paroxysmal AF (PAF) and AFL. METHODS AND RESULTS:Ninety-eight patients with PAF/AFL were prospectiv...

journal_title：Circulation

authors： Moreira W,Timmermans C,Wellens HJ,Mizusawa Y,Philippens S,Perez D,Rodriguez LM

更新日期：2007-12-11 00:00:00

abstract：BACKGROUND:AMP-activated protein kinase (AMPK) is a stress-activated protein kinase that works as a metabolic sensor of cellular ATP levels. Here, we investigated whether AMPK signaling has a role in the regulation of the angiotensin II (Ang II)-induced proliferation signal in rat vascular smooth muscle cells (VSMCs). ...

journal_title：Circulation

authors： Nagata D,Takeda R,Sata M,Satonaka H,Suzuki E,Nagano T,Hirata Y

更新日期：2004-07-27 00:00:00

abstract：BACKGROUND:Extrahepatic tissues have long been considered critical contributors of cholesterol to nascent HDL particles in the reverse cholesterol transport pathway, in which ABCA1 plays the crucial role. Recent studies, however, including both overexpression and deletion of ABCA1 selectively in the liver, have highlig...

journal_title：Circulation

authors： Singaraja RR,Van Eck M,Bissada N,Zimetti F,Collins HL,Hildebrand RB,Hayden A,Brunham LR,Kang MH,Fruchart JC,Van Berkel TJ,Parks JS,Staels B,Rothblat GH,Fiévet C,Hayden MR

更新日期：2006-09-19 00:00:00

abstract：:We examined the influence of left ventricular end-diastolic pressure (LVEDP) on the mechanical interaction between ischemic and nonischemic areas during acute myocardial ischemia. Circumferentially oriented ultrasonic segment gauges were implanted in the midwall of the anterior apex and posterior apex of the left vent...

journal_title：Circulation

authors： Lew WY,Ban-Hayashi E

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:Development and validation of novel imaging modalities to assess the composition of human atherosclerotic plaques will improve the understanding of atheroma evolution and could facilitate evaluation of therapeutic strategies for plaque modification. Surface MRI can characterize tissue content of carotid but ...

journal_title：Circulation

authors： Larose E,Yeghiazarians Y,Libby P,Yucel EK,Aikawa M,Kacher DF,Aikawa E,Kinlay S,Schoen FJ,Selwyn AP,Ganz P

更新日期：2005-10-11 00:00:00

abstract：BACKGROUND:Monocyte chemoattractant protein-1 (MCP-1) is a chemokine responsible for the recruitment of monocytes to sites of inflammation. MCP-1 appears to play a critical role at multiple stages in atherosclerosis, including the initiation of the fatty streak, promotion of plaque instability, and remodeling after myo...

journal_title：Circulation

authors： de Lemos JA,Morrow DA,Sabatine MS,Murphy SA,Gibson CM,Antman EM,McCabe CH,Cannon CP,Braunwald E

更新日期：2003-02-11 00:00:00

abstract：BACKGROUND:Because acute exercise increases systemic catecholamines, we sought to determine whether exercise training would alter daily or exercise-related catecholamine release and inactivation. METHODS AND RESULTS:In 24-hour urine collections, catecholamines and metabolites provided indexes of overall oxidative deam...

journal_title：Circulation

authors： Rogers PJ,Tyce GM,Weinshilboum RM,O'Connor DT,Bailey KR,Bove AA

更新日期：1991-12-01 00:00:00

abstract：:Verapamil, a calcium antagonist, has been used extensively for treatment of cardiac arrhythmias. Concern persists, however, that it may seriously depress myocardial function in cardiac patients. To investigate this possibility, 20 patients with coronary artery disease (CAD) but no heart failure were given intravenous ...

journal_title：Circulation

authors： Ferlinz J,Easthope JL,Aronow WS

更新日期：1979-02-01 00:00:00

abstract：:Reperfusion of ischemic myocardium may accelerate necrosis of injured myocytes. To determine the role of neutrophil leukocytes in this process, we examined whether neutrophil depletion during reperfusion could modify infarct size in anesthetized dogs. The proximal circumflex coronary artery was occluded for 90 minutes...

journal_title：Circulation

authors： Litt MR,Jeremy RW,Weisman HF,Winkelstein JA,Becker LC

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:Temporal trends regarding the epidemiology of atherosclerotic renovascular disease (ARVD) in dialysis populations are poorly defined. METHODS AND RESULTS:United States Renal Data System data were used to identify patients aged 67 years or older at dialysis inception between 1996 and 2001 (n=146,973). Medica...

journal_title：Circulation

authors： Guo H,Kalra PA,Gilbertson DT,Liu J,Chen SC,Collins AJ,Foley RN

更新日期：2007-01-02 00:00:00

abstract：BACKGROUND:Compared with single-chamber ventricular pacing, dual-chamber pacing can reduce adverse events and, as a result, improve quality of life in patients paced for sick sinus syndrome. It is not clear, however, how these benefits compare with the increased cost of dual-chamber pacemakers. METHODS AND RESULTS:We ...

journal_title：Circulation

authors： Rinfret S,Cohen DJ,Lamas GA,Fleischmann KE,Weinstein MC,Orav J,Schron E,Lee KL,Goldman L

更新日期：2005-01-18 00:00:00

abstract：BACKGROUND:Despite improvements in management, infective endocarditis remains associated with high mortality and morbidity. We describe temporal changes in the incidence, microbiology, and outcomes of infective endocarditis and the effect of changes in national antibiotic prophylaxis guidelines on incident infective en...

journal_title：Circulation

authors： Shah ASV,McAllister DA,Gallacher P,Astengo F,Rodríguez Pérez JA,Hall J,Lee KK,Bing R,Anand A,Nathwani D,Mills NL,Newby DE,Marwick C,Cruden NL

更新日期：2020-06-23 00:00:00

abstract：BACKGROUND:The purpose of this study was to describe a new technique for catheter ablation of left lateral accessory pathways (APs) by radiofrequency energy applied at the epicardium through the coronary sinus wall using a unipolar configuration. METHODS AND RESULTS:In an overall group of 212 patients with left latera...

journal_title：Circulation

authors： Haissaguerre M,Gaita F,Fischer B,Egloff P,Lemetayer P,Warin JF

更新日期：1992-11-01 00:00:00

abstract：:Twenty-four hour noninvasive ambulatory blood pressure and heart rate monitoring was performed on patients who underwent orthotopic cardiac transplantation, as part of the investigation of the de novo hypertension that developes in such patients. Patients with essential hypertension served as control subjects. The res...

journal_title：Circulation

authors： Reeves RA,Shapiro AP,Thompson ME,Johnsen AM

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Titin is a giant elastic protein that spans the half-sarcomere from Z-disk to M-band. It acts as a molecular spring and mechanosensor and has been linked to striated muscle disease. The pathways that govern titin-dependent cardiac growth and contribute to disease are diverse and difficult to dissect. METHOD...

journal_title：Circulation

authors： Radke MH,Polack C,Methawasin M,Fink C,Granzier HL,Gotthardt M

更新日期：2019-04-09 00:00:00

abstract：BACKGROUND:Sporadic aortic aneurysm and dissection (AAD), caused by progressive aortic smooth muscle cell (SMC) loss and extracellular matrix degradation, is a highly lethal condition. Identifying mechanisms that drive aortic degeneration is a crucial step in developing an effective pharmacologic treatment to prevent d...

journal_title：Circulation

authors： Luo W,Wang Y,Zhang L,Ren P,Zhang C,Li Y,Azares AR,Zhang M,Guo J,Ghaghada KB,Starosolski ZA,Rajapakshe K,Coarfa C,Li Y,Chen R,Fujiwara K,Abe JI,Coselli JS,Milewicz DM,LeMaire SA,Shen YH

更新日期：2020-01-07 00:00:00

abstract：BACKGROUND:The long-term success of coronary bypass surgery is dependent on graft patency after surgery. This trial was designed to determine if aspirin improved saphenous vein graft or internal mammary artery (IMA) graft patency between 1 and 3 years after coronary artery bypass grafting (CABG). METHODS AND RESULTS:A...

journal_title：Circulation

authors： Goldman S,Copeland J,Moritz T,Henderson W,Zadina K,Ovitt T,Kern KB,Sethi G,Sharma GV,Khuri S

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Patients with atrial fibrillation (AF) often take multiple medications. METHODS AND RESULTS:We examined characteristics and compared adjusted outcomes between rivaroxaban and warfarin according to number of concomitant baseline medications and the presence of combined cytochrome P450 3A4 and P-glycoprotein ...

journal_title：Circulation

authors： Piccini JP,Hellkamp AS,Washam JB,Becker RC,Breithardt G,Berkowitz SD,Halperin JL,Hankey GJ,Hacke W,Mahaffey KW,Nessel CC,Singer DE,Fox KA,Patel MR

更新日期：2016-01-26 00:00:00

abstract：BACKGROUND:The Doppler wire-derived (relative) coronary flow velocity reserve (CVR) that is used to evaluate functional significance of a coronary stenosis is a method performed only by interventional cardiologists. An angiographic method would be useful in the diagnostic catheterization laboratory. For this purpose, w...

journal_title：Circulation

authors： Stoel MG,Zijlstra F,Visser CA

更新日期：2003-06-24 00:00:00

abstract：BACKGROUND:Cardiomyocyte hypertrophy is a critical precursor to the development of heart failure. Methods to phenotype cellular hypertrophy noninvasively are limited. The goal was to validate a cardiac magnetic resonance-based approach for the combined assessment of extracellular matrix expansion and cardiomyocyte hype...

journal_title：Circulation

authors： Coelho-Filho OR,Shah RV,Mitchell R,Neilan TG,Moreno H Jr,Simonson B,Kwong R,Rosenzweig A,Das S,Jerosch-Herold M

更新日期：2013-09-10 00:00:00

abstract：:A transvenous lead system for implantable defibrillators would obviate a surgical thoracotomy and reduce the morbidity and mortality associated with implantation. We evaluated the clinical performance of a new nonthoracotomy lead system that included a defibrillation lead in the coronary sinus. At the time of defibril...

journal_title：Circulation

authors： Yee R,Klein GJ,Leitch JW,Guiraudon GM,Guiraudon CM,Jones DL,Norris C

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Cardiovascular disease is the major cause of death in older women. Information on the relation of menopause and hormone replacement therapy with carotid atherosclerosis is limited. METHODS AND RESULTS:We examined cross-sectionally the association of menopausal status, years since last menstruation, and horm...

journal_title：Circulation

authors： Nabulsi AA,Folsom AR,Szklo M,White A,Higgins M,Heiss G

更新日期：1996-10-15 00:00:00

abstract：BACKGROUND:Mendelian randomization studies have highlighted that lipoprotein(a) [Lp(a)] was associated with calcific aortic valve disease (CAVD). Lp(a) transports oxidized phospholipids with a high content in lysophosphatidylcholine. Autotaxin (ATX) transforms lysophosphatidylcholine into lysophosphatidic acid. We hypo...

journal_title：Circulation

authors： Bouchareb R,Mahmut A,Nsaibia MJ,Boulanger MC,Dahou A,Lépine JL,Laflamme MH,Hadji F,Couture C,Trahan S,Pagé S,Bossé Y,Pibarot P,Scipione CA,Romagnuolo R,Koschinsky ML,Arsenault BJ,Marette A,Mathieu P

更新日期：2015-08-25 00:00:00

abstract：:One of the noninvasive methods of evaluating left ventricular performance is the measurement of left ventricular systolic time intervals (LVSTI). However, noninvasive measurement of right ventricular systole by this technique has been unreliable because of the inability to accurately time the onset of right ventricula...

journal_title：Circulation

authors： Hirschfeld S,Meyer R,Schwartz DC,Korfhagen J,Kaplan S

更新日期：1975-02-01 00:00:00