Carotid endarterectomy based on duplex scanning without preoperative arteriography.

abstract：BACKGROUND:Direct thrombin inhibitors are a new class of drugs that may offer a more effective and potentially simpler alternative to heparin. Hirulog is a synthetic peptide based on the leech-derived compound hirudin and, like hirudin, is a highly specific, direct inhibitor of free and clot-bound thrombin. METHODS AN...

journal_title：Circulation

authors： Fuchs J,Cannon CP

更新日期：1995-08-15 00:00:00

abstract：:One hundred four patients younger than 20 years of age underwent intracardiac xenograft valve replacement (n = 41) or extracardiac conduit implantation (n = 63). Long-term follow-up averaged 4.5 and 4.3 years, respectively, and cumulative follow-up totaled 344 patient-years (pt-yr). Thirty patients were followed more ...

journal_title：Circulation

authors： Miller DC,Stinson EB,Oyer PE,Billingham ME,Pitlick PT,Reitz BA,Jamieson SW,Baumgartner WA,Shumway NE

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND:The site of cannulation for repair of ascending aortic dissection remains controversial. We present our experience with ascending aortic cannulation for acute aortic dissection type A. METHODS AND RESULTS:From January 1988 to September 2007, we operated on 242 patients for acute aortic dissection type A. Me...

journal_title：Circulation

authors： Kamiya H,Kallenbach K,Halmer D,Ozsöz M,Ilg K,Lichtenberg A,Karck M

更新日期：2009-09-15 00:00:00

abstract：BACKGROUND:Associations between left ventricular (LV) geometry and the insulin resistance syndrome have been found, mostly in small studies of middle-aged hypertensives. The purpose of this study was to elucidate these associations through the use of a large sample of elderly men. METHODS AND RESULTS:We investigated 4...

journal_title：Circulation

authors： Sundström J,Lind L,Nyström N,Zethelius B,Andrén B,Hales CN,Lithell HO

更新日期：2000-06-06 00:00:00

abstract：BACKGROUND:We explored the feasibility of measuring regional tracer activity concentrations and flow defects in myocardium of rats with a high spatial resolution small-animal PET system (microPET). METHODS AND RESULTS:Myocardial images were obtained after intravenous (18)F-fluorodeoxyglucose (18FDG) in 11 normal rats ...

journal_title：Circulation

authors： Kudo T,Fukuchi K,Annala AJ,Chatziioannou AF,Allada V,Dahlbom M,Tai YC,Inubushi M,Huang SC,Cherry SR,Phelps ME,Schelbert HR

更新日期：2002-07-02 00:00:00

abstract：BACKGROUND:Memory is a diverse biological phenomenon whose importance in the ventricle has been demonstrated. We hypothesized its occurrence in the atrium, contributing to the modulation of cardiac rhythm. METHODS AND RESULTS:We analyzed P and Ta waves in conscious chronically instrumented dogs with complete heart blo...

journal_title：Circulation

authors： Herweg B,Chang F,Chandra P,Danilo P Jr,Rosen MR

更新日期：2001-01-23 00:00:00

abstract：BACKGROUND:Despite successful surgical correction, morbidity of patients with coarctation of the aorta is increased. It is well known that these patients have impaired elastic properties of the prestenotic arteries. To find out whether these abnormalities are primarily present or develop later, we studied 17 newborns b...

journal_title：Circulation

authors： Vogt M,Kühn A,Baumgartner D,Baumgartner C,Busch R,Kostolny M,Hess J

更新日期：2005-06-21 00:00:00

abstract：BACKGROUND:Mildly oxidized LDL (moxLDL) is thought to play a role in atherogenesis. MoxLDL induces derivatization of cell proteins and triggers a variety of intracellular signaling. We aimed to investigate whether moxLDL-induced protein derivatization may influence the activity of platelet-derived growth factor recepto...

journal_title：Circulation

authors： Escargueil-Blanc I,Salvayre R,Vacaresse N,Jürgens G,Darblade B,Arnal JF,Parthasarathy S,Nègre-Salvayre A

更新日期：2001-10-09 00:00:00

abstract：BACKGROUND:Microvascular dysfunction posttreatment of stroke with recombinant human tissue-type plasminogen activator (rht-PA) constrains the therapeutic window to 3 hours. Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) promote vascular thrombolysis and reduce the inflammation response. We therefo...

journal_title：Circulation

authors： Zhang L,Zhang ZG,Ding GL,Jiang Q,Liu X,Meng H,Hozeska A,Zhang C,Li L,Morris D,Zhang RL,Lu M,Chopp M

更新日期：2005-11-29 00:00:00

abstract：BACKGROUND:Increased common carotid artery intima-media thickness (CCA-IMT) is a marker of early atherosclerosis. Low-grade inflammation is associated with the pathogenesis of atherosclerosis. Low-grade inflammation and increased CCA-IMT are observed in end-stage renal disease (ESRD). Oxidative stress is involved in ur...

journal_title：Circulation

authors： Drüeke T,Witko-Sarsat V,Massy Z,Descamps-Latscha B,Guerin AP,Marchais SJ,Gausson V,London GM

更新日期：2002-10-22 00:00:00

abstract：:Although the resting hemodynamic effects of captopril in congestive heart failure are known, little information is available about the hemodynamic response to captopril during exercise or about changes in noninvasive measurements of the size and function of both ventricles. In this study, 14 stable New York Heart Asso...

journal_title：Circulation

authors： Massie B,Kramer BL,Topic N,Henderson SG

更新日期：1982-06-01 00:00:00

abstract：:To define the role of portable two-dimensional echocardiography (2-D echo) in the immediate diagnosis of acute chest pain syndrome, 80 consecutive patients were studied. Adequate 2-D echo studies were obtained in 65 (81%). Thirty-three patients had clinical evidence of transmural or nontransmural acute myocardial infa...

journal_title：Circulation

authors： Horowitz RS,Morganroth J,Parrotto C,Chen CC,Soffer J,Pauletto FJ

更新日期：1982-02-01 00:00:00

abstract：BACKGROUND:Endothelial integrity is essential for maintaining vascular homeostasis, and endothelial denudation results in neointimal thickening. Balloon-expandable endovascular stents provide a luminal scaffolding within atherosclerotic arteries with minimal direct contact between balloon and endothelium. We wondered w...

journal_title：Circulation

authors： Rogers C,Parikh S,Seifert P,Edelman ER

更新日期：1996-12-01 00:00:00

abstract：:Medical treatment of heart disease has improved significantly in the past 30 years. The spectacular change in the natural history of rheumatic heart disease is apparent from a 1948 article that reported that 42% of children with rheumatic heart disease died of rheumatic infection or bacterial endocarditis. Antibiotics...

journal_title：Circulation

authors： Ross RS

更新日期：1979-12-01 00:00:00

abstract：:Esophageal perforation is a dreaded complication of atrial fibrillation ablation that occurs in 0.1% to 0.25% of atrial fibrillation ablation procedures. Delayed diagnosis is associated with the development of atrial-esophageal fistula (AEF) and increased mortality. The relationship between the esophagus and the left ...

journal_title：Circulation

authors： Kapur S,Barbhaiya C,Deneke T,Michaud GF

更新日期：2017-09-26 00:00:00

abstract：BACKGROUND:Several mortality risk scores exist in cardiac surgery. All include a considerable number of independent risk factors. In elective cardiac surgery patients, the operative mortality is low, the number of events recorded per year is limited, and the risk model may be overfitted. The present study aims to devel...

journal_title：Circulation

authors： Ranucci M,Castelvecchio S,Menicanti L,Frigiola A,Pelissero G

更新日期：2009-06-23 00:00:00

abstract：BACKGROUND:The application of iloprost, a stable prostacyclin analogue, by inhalation has been shown to improve hemodynamic variables in patients with primary pulmonary hypertension. However, repetitive inhalations are required due to its short-term effects. One potential approach to prolong and increase the vasorelaxa...

journal_title：Circulation

authors： Wilkens H,Guth A,König J,Forestier N,Cremers B,Hennen B,Böhm M,Sybrecht GW

更新日期：2001-09-11 00:00:00

abstract：BACKGROUND:Recent data highlight a vital link between well-performed cardiopulmonary resuscitation (CPR) and survival after cardiac arrest; however, the quality of CPR as actually performed by trained healthcare providers is largely unknown. We sought to measure in-hospital chest compression rates and to determine comp...

journal_title：Circulation

authors： Abella BS,Sandbo N,Vassilatos P,Alvarado JP,O'Hearn N,Wigder HN,Hoffman P,Tynus K,Vanden Hoek TL,Becker LB

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:We have previously demonstrated vasculoprotective effects after repeated intravenous administration of recombinant apolipoprotein A-IMilano (apoA-Im)/phospholipid complex. In this study, we sought to determine the effects of local recombinant apoA-Im/1-palmitoyl,2-oleoyl phosphatidylcholine complex (ETC-216)...

journal_title：Circulation

authors： Kaul S,Rukshin V,Santos R,Azarbal B,Bisgaier CL,Johansson J,Tsang VT,Chyu KY,Cercek B,Mirocha J,Shah PK

更新日期：2003-05-27 00:00:00

abstract：BACKGROUND:Atrial dysrhythmia patients have exaggerated intra-atrial conduction delays and prolonged relative refractoriness in response to atrial premature depolarizations (APDs). Furthermore, atrial fibrillation (AF) is more readily inducible by APDs from the high right atrium (HRA) than the coronary sinus (CS). In t...

journal_title：Circulation

authors： Papageorgiou P,Monahan K,Boyle NG,Seifert MJ,Beswick P,Zebede J,Epstein LM,Josephson ME

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Collaterals limit infarct size, preserve viability, and reduce mortality in patients with acute myocardial infarction. In patients with stable coronary disease, collaterals are associated with less angina and ischemia during angioplasty and fewer ischemic events during follow-up. The role of collaterals has ...

journal_title：Circulation

authors： Nathoe HM,Buskens E,Jansen EW,Suyker WJ,Stella PR,Lahpor JR,van Boven WJ,van Dijk D,Diephuis JC,Borst C,Moons KG,Grobbee DE,de Jaegere PP

更新日期：2004-09-28 00:00:00

abstract：BACKGROUND:Several studies have observed an inverse association between height and risk for coronary disease, but it is unclear whether other traditional coronary disease risk factors may have confounded this association. We examined the original Framingham Heart Study cohort to determine whether short stature is assoc...

journal_title：Circulation

authors： Kannam JP,Levy D,Larson M,Wilson PW

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Coronary spastic angina (CSA) is a common disease among East Asians, including Japanese. The prevalence of alcohol flushing syndrome associated with deficient activity of the variant aldehyde dehydrogenase 2 (ALDH2*2) genotype is prevalent among East Asians. We examined whether CSA is associated with the ALD...

journal_title：Circulation

authors： Mizuno Y,Harada E,Morita S,Kinoshita K,Hayashida M,Shono M,Morikawa Y,Murohara T,Nakayama M,Yoshimura M,Yasue H

更新日期：2015-05-12 00:00:00

abstract：BACKGROUND:It is well established that a depressed baroreflex sensitivity may adversely influence the prognosis in patients with chronic heart failure (CHF) and in those with previous myocardial infarction. METHODS AND RESULTS:We tested whether a slow breathing rate (6 breaths/min) could modify the baroreflex sensitiv...

journal_title：Circulation

authors： Bernardi L,Porta C,Spicuzza L,Bellwon J,Spadacini G,Frey AW,Yeung LY,Sanderson JE,Pedretti R,Tramarin R

更新日期：2002-01-15 00:00:00

abstract：BACKGROUND:Lymphatic network and chemokine-mediated signals are essential for leukocyte traffic during the proximal steps of alloimmune response. We aimed to determine the role of lymphatic vessels and their principal growth signaling pathway, vascular endothelial growth factor (VEGF)-C/D/VEGFR-3, during acute and chro...

journal_title：Circulation

authors： Nykänen AI,Sandelin H,Krebs R,Keränen MA,Tuuminen R,Kärpänen T,Wu Y,Pytowski B,Koskinen PK,Ylä-Herttuala S,Alitalo K,Lemström KB

更新日期：2010-03-30 00:00:00

abstract：BACKGROUND:Previous evidence has shown that increased sympathetic tone enhances the cesium chloride (Cs)-induced early afterdepolarizations (EADs) and ventricular tachycardias (VTs). METHODS AND RESULTS:We assessed the effects of vagal stimulation on Cs-induced EADs and ventricular arrhythmias in the rabbit heart. Mon...

journal_title：Circulation

authors： Takahashi N,Ito M,Ishida S,Fujino T,Saikawa T,Arita M

更新日期：1992-12-01 00:00:00

abstract：:Nineteen patients with chronic low output cardiac failure were studied before, during and after infusion of phentolamine in doses of 10, 20, 30 and 40 microgram/kg/min. Significant reduction of left- and right-sided pressures and increases in cardiac index and heart rate (HR) were present within 15 minutes of starting...

journal_title：Circulation

authors： Stern MA,Gohlke HK,Loeb HS,Croke RP,Gunnar RM

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND:Two phase III trials of enoxaparin for unstable angina/non-Q-wave myocardial infarction have shown it to be superior to unfractionated heparin for preventing a composite of death and cardiac ischemic events. A prospectively planned meta-analysis was performed to provide a more precise estimate of the effects...

journal_title：Circulation

authors： Antman EM,Cohen M,Radley D,McCabe C,Rush J,Premmereur J,Braunwald E

更新日期：1999-10-12 00:00:00

abstract：:Genetic analysis can be performed to identify the molecular substrate of inherited arrhythmogenic diseases; however, the role of this information in helping the management of patients is still debated. Here, we support the view that the practical value of genetic analysis is different in the various inherited conditio...

journal_title：Circulation

authors： Priori SG,Napolitano C

更新日期：2006-02-28 00:00:00

abstract：BACKGROUND:Clinical studies have implicated preinfarct angina (brief antecedent ischemia/reperfusion [I/R]) as a predictor of more rapid thrombolysis and lower rates of reocclusion. However, the effects of antecedent ischemia on the efficacy of thrombolysis have not been rigorously assessed. Using a canine model of cor...

journal_title：Circulation

authors： Przyklenk K,Whittaker P

更新日期：2000-07-04 00:00:00