Abstract:
:To define the role of portable two-dimensional echocardiography (2-D echo) in the immediate diagnosis of acute chest pain syndrome, 80 consecutive patients were studied. Adequate 2-D echo studies were obtained in 65 (81%). Thirty-three patients had clinical evidence of transmural or nontransmural acute myocardial infarction (AMI), 18 of whom had nondiagnostic initial ECGs. Thirty-two did not have a clinical AMI. Thirty-one of the 33 (94%) patients with clinical AMI had regional wall motion abnormalities on the initial 2-D echo; the other two had uncomplicated nontransmural AMIs, diagnosed only by ECG in one and by ECG and moderate elevation of CK-MB isoenzyme in the other. Twenty-seven of the 32 patients without clinical AMI had normal regional wall motion on the initial 2-D echo and none had a complication (severe arrhythmia, recurrent pain, heart failure or death) during the hospital course. Conversely, 10 of the 36 patients with initial 2-D echo regional wall motion abnormalities had a complication (p less than 0.05). Thus, in patients with acute chest pain syndrome, an initial 2-D echo that shows no regional wall motion abnormality suggests that such patients will not develop an AMI or clinical complication during the hospital course. An initial 2-D echo with regional wall motion abnormality identifies a high-risk group of patients who are likely to have AMI and important cardiac complications and may, therefore, benefit from admission to an intensive care unit.
journal_name
Circulationjournal_title
Circulationauthors
Horowitz RS,Morganroth J,Parrotto C,Chen CC,Soffer J,Pauletto FJdoi
10.1161/01.cir.65.2.323subject
Has Abstractpub_date
1982-02-01 00:00:00pages
323-9issue
2eissn
0009-7322issn
1524-4539journal_volume
65pub_type
杂志文章相关文献
CIRCULATION文献大全abstract::We used Doppler echocardiography to quantitate the changes in intracardiac blood flow velocities and right and left ventricular stroke volumes in 80 normal human fetuses from 19 to 40 weeks gestation. Blood flow velocity spectra across the aortic, pulmonary, tricuspid, and mitral valves were digitized to obtain peak v...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.74.6.1208
更新日期:1986-12-01 00:00:00
abstract:BACKGROUND:We have developed a new measure of myocardial viability, the water-perfusable tissue index (PTI), which is calculated from transmission, C15O, and H2(15)O positron emission tomography (PET) data sets. It is defined as the proportion of the total anatomical tissue within a given region of interest (ROI) that ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.86.1.167
更新日期:1992-07-01 00:00:00
abstract:BACKGROUND:Diabetes mellitus is a predictor of morbidity and mortality in patients with heart failure. The effect of angiotensin-converting enzyme (ACE) inhibitors on the prevention of diabetes in patients with left ventricular dysfunction is unknown. The aim of this retrospective study was to assess the effect of the ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.0000054611.89228.92
更新日期:2003-03-11 00:00:00
abstract:BACKGROUND:Giant cell myocarditis (GCM) typically causes fulminant heart failure, arrhythmias, or heart block, necessitating aggressive immunosuppression, ventricular assist device insertion, or cardiac transplantation. We describe a novel variant of GCM, primarily involving the atria, that displays distinctive clinica...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.112.128900
更新日期:2013-01-01 00:00:00
abstract::In this report we describe electrophysiologic and histologic findings in hearts and endocardially resected preparations from patients with sustained ventricular tachycardias in the chronic phase of myocardial infarction. We recorded simultaneously from 64 endocardial sites during tachycardia in 72 patients that were o...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.77.3.589
更新日期:1988-03-01 00:00:00
abstract::Considerable variability was observed among recruitment sources and centers in the proportion of first protocol visits proceeding to entry. Some of the reasons for these differences are explored. Several characteristics of the participants were also analyzed to determine whether significant variability existed among r...
journal_title:Circulation
pub_type: 杂志文章
doi:
更新日期:1982-12-01 00:00:00
abstract::In this study we quantitated the region of preserved myocardium between a subendocardial myocardial infarct (SEMI) and the endocardium in dogs and determined whether this preserved zone was within the region at risk and whether infarct extension could occur in this region. We also evaluated whether a similar subendoca...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.67.1.117
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND:Heart failure (HF) is responsible for a huge burden in hospital care. Our goal was to evaluate the value of N-terminal-pro-brain natriuretic peptide (NT-proBNP) in predicting death or hospital readmission after discharge of HF patients. METHODS AND RESULTS:We included 182 patients consecutively admitted to ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.CIR.0000144310.04433.BE
更新日期:2004-10-12 00:00:00
abstract:BACKGROUND:Varicose veins are a common problem with no approved medical therapies. Although it is believed that varicose vein pathogenesis is multifactorial, there is limited understanding of the genetic and environmental factors that contribute to their formation. Large-scale studies of risk factors for varicose veins...
journal_title:Circulation
pub_type: 杂志文章,多中心研究
doi:10.1161/CIRCULATIONAHA.118.035584
更新日期:2018-12-18 00:00:00
abstract::Endocardial catheter mapping was performed in 15 patients in sinus rhythm who had no evidence of structural heart disease and normal left ventricles. Mapping was performed with the use of 10 mm interelectrode distance from various left ventricular endocardial sites. In 10 patients a quantitative analysis of electrogra...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.70.1.37
更新日期:1984-07-01 00:00:00
abstract:BACKGROUND:A completed Fontan circulation is the goal in the management of patients with single-ventricle physiology. To achieve this end, a two-stage rather than a single-stage approach is carried out routinely at many centers. Some groups have advocated baffle fenestration for virtually all patients to minimize post-...
journal_title:Circulation
pub_type: 杂志文章
doi:
更新日期:1997-11-04 00:00:00
abstract:BACKGROUND:Mechanisms by which neutrophils are attracted to the myocardium in ischemia/reperfusion are not fully defined. Lipopolysaccharide-induced CXC chemokine (LIX), cytokine-induced neutrophil chemoattractant (KC), and macrophage inflammatory protein-2 (MIP-2) are rodent chemokines with potent neutrophil-chemotact...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.103.18.2296
更新日期:2001-05-08 00:00:00
abstract:BACKGROUND:Metformin is first-line therapy for type 2 diabetes mellitus, although its effects on the cardiovascular system are unproved. METHODS:In this post hoc analysis, patients in SAVOR-TIMI 53 (Saxagliptin and Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus) with baseline biomarker samples (n=12...
journal_title:Circulation
pub_type: 临床试验,杂志文章
doi:10.1161/CIRCULATIONAHA.119.040144
更新日期:2019-09-17 00:00:00
abstract:BACKGROUND:Compared with single-chamber ventricular pacing, dual-chamber pacing can reduce adverse events and, as a result, improve quality of life in patients paced for sick sinus syndrome. It is not clear, however, how these benefits compare with the increased cost of dual-chamber pacemakers. METHODS AND RESULTS:We ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.CIR.0000151810.69732.41
更新日期:2005-01-18 00:00:00
abstract:BACKGROUND:The incidence of pulmonary arterial hypertension secondary to the use of indirect serotinergic agonists such as aminorex and dexfenfluramine led to the "serotonin hypothesis" of pulmonary arterial hypertension; however, the role of serotonin in dexfenfluramine-induced pulmonary arterial hypertension remains ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.108.767558
更新日期:2008-06-03 00:00:00
abstract::When acute myocardial infarction occurs in patients with hypertension and left ventricular hypertrophy (LVH), the incidence of sudden cardiac death increases markedly. Possible explanations include increased size of the occluded vascular bed secondary to more extensive atherosclerotic coronary vascular disease in the ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.65.6.1192
更新日期:1982-06-01 00:00:00
abstract::The elimination of specific dietary cholesterol target recommendations in recent guidelines has raised questions about its role with respect to cardiovascular disease. This advisory was developed after a review of human studies on the relationship of dietary cholesterol with blood lipids, lipoproteins, and cardiovascu...
journal_title:Circulation
pub_type: 杂志文章,meta分析
doi:10.1161/CIR.0000000000000743
更新日期:2020-01-21 00:00:00
abstract:BACKGROUND:Ibutilide is an action potential-prolonging antiarrhythmic currently in clinical trials. The drug shares structural similarities with E-4031 and dofetilide, specific blockers of the rapidly activating delayed rectifier K+ current (IKr). However, previous in vitro studies in guinea pig myocytes have indicated...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.91.6.1799
更新日期:1995-03-15 00:00:00
abstract:BACKGROUND:It remains unclear how mineralocorticoids induce cardiac hypertrophy and fibrosis. Recently, activation of the calcium-dependent phosphatase, calcineurin, has been shown to induce cardiac hypertrophy. In the present study, we examine the role of calcineurin in mineralocorticoid-induced cardiac hypertrophy an...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/hc0602.104675
更新日期:2002-02-12 00:00:00
abstract:BACKGROUND:Intracranial hemorrhage is the most feared complication of oral anticoagulant treatment. The optimal treatment option for patients with atrial fibrillation who survive an intracranial hemorrhage remains unknown. We hypothesized that restarting oral anticoagulant treatment was associated with a lower risk of ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.115.015735
更新日期:2015-08-11 00:00:00
abstract::We evaluated the accuracy of the recently reported technique of estimating intraventricular volume by measurement of intracavitary electrical conductance in six isolated, ejecting, canine left ventricles. Left ventricular volumes were measured directly by a previously validated servosystem that employed an electrocond...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.72.2.440
更新日期:1985-08-01 00:00:00
abstract:BACKGROUND:Activation of protein kinase C-linked receptors and subsequent opening of the mitochondrial ATP-sensitive K(+) (mitoK(ATP)) channel are crucial in preconditioning (PC). This study examined whether postinfarct ventricular remodeling interferes with the PC mechanism. METHODS AND RESULTS:Two weeks before isola...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.102.4.458
更新日期:2000-07-25 00:00:00
abstract:BACKGROUND:Serotonin (5-hydroxytryptamine; 5-HT) overproduction is responsible for cardiac valvular disease in patients with carcinoid tumors. Reduced 5-HT inactivation is one proposed mechanism of the valvulopathy observed in individuals treated with the appetite suppressants fenfluramine and phentermine. One key prot...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.105.554667
更新日期:2006-01-03 00:00:00
abstract:BACKGROUND:After repair of aortic coarctation, patients may develop restenosis, aneurysms, and pseudoaneurysms at the site of prior repair. We assessed the outcomes of late reintervention on the descending aorta after aortic coarctation repair. METHODS AND RESULTS:From March 1954 to July 2008, 130 patients had operati...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.109.925172
更新日期:2010-09-14 00:00:00
abstract:BACKGROUND:Coxsackieviruses B (CBVs) are dominant causative agents in myocarditis and are associated with pathogenesis is some cases of dilated cardiomyopathy, a clinical entity with a poor survival without heart transplantation. METHODS AND RESULTS:In vitro, the antiviral agent WIN 54 954 was shown to inhibit replica...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.94.9.2254
更新日期:1996-11-01 00:00:00
abstract::In a group of 39 patients who received fibrinolytic therapy for acute myocardial infarction, serum crosslinked fibrin degradation products (XLDP) were quantitated by an enzyme-linked immunosorbent assay (ELISA) using an antibody reactive with a site near the gamma gamma crosslink of fibrin, and characterized by a gel ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.74.5.1027
更新日期:1986-11-01 00:00:00
abstract::Scanning and transmission electron microscopic studies were made of: 1) 15 glutaraldehyde-treated porcine valvular heterografts that had been implanted in patients for periods of time ranging from 2 days to 76 months; 2) unimplanted, commercially processed porcine aortic valves; and 3) unprocessed porcine aortic valve...
journal_title:Circulation
pub_type: 杂志文章
doi:
更新日期:1978-09-01 00:00:00
abstract::Survival rates were determined for a group of 598 patients in whom severe coronary disease was demonstrated by arteriography; initially they were treated medically and were followed-up for 15 years. Deaths due to noncoronary causes were uncommon (5% of total) in the first 5 year period but were frequent (36%) in the t...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.68.5.986
更新日期:1983-11-01 00:00:00
abstract:BACKGROUND:Cardiomyocyte hypertrophy is a critical precursor to the development of heart failure. Methods to phenotype cellular hypertrophy noninvasively are limited. The goal was to validate a cardiac magnetic resonance-based approach for the combined assessment of extracellular matrix expansion and cardiomyocyte hype...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.112.000438
更新日期:2013-09-10 00:00:00
abstract:BACKGROUND:We have previously suggested that the primary arterial switch operation is a feasible strategy for patients with transposition of the great arteries and intact ventricular septum (TGA-IVS) up to age 2 months. This study reports our current results with this approach and examines whether this policy could be ...
journal_title:Circulation
pub_type: 杂志文章,评审
doi:10.1161/01.CIR.0000138221.68312.33
更新日期:2004-09-14 00:00:00