Cost-effectiveness of dual-chamber pacing compared with ventricular pacing for sinus node dysfunction.

abstract：BACKGROUND:Clinical manifestations of acute myocarditis, with distinct onset, vary from asymptomatic to fatal. The predictors of the course of the disease in patients with acute myocarditis at initial presentation have not yet been established. In this study, we examined the predictive values of various parameters in t...

journal_title：Circulation

authors： Fuse K,Kodama M,Okura Y,Ito M,Hirono S,Kato K,Hanawa H,Aizawa Y

更新日期：2000-12-05 00:00:00

abstract：BACKGROUND:This study evaluated the hypothesis that transendocardial injections of autologous mononuclear bone marrow cells in patients with end-stage ischemic heart disease could safely promote neovascularization and improve perfusion and myocardial contractility. METHODS AND RESULTS:Twenty-one patients were enrolled...

journal_title：Circulation

authors： Perin EC,Dohmann HF,Borojevic R,Silva SA,Sousa AL,Mesquita CT,Rossi MI,Carvalho AC,Dutra HS,Dohmann HJ,Silva GV,Belém L,Vivacqua R,Rangel FO,Esporcatte R,Geng YJ,Vaughn WK,Assad JA,Mesquita ET,Willerson JT

更新日期：2003-05-13 00:00:00

abstract：BACKGROUND:In vivo testing of novel antiplatelet agents requires informative biomarkers. By genetically modifying mouse von Willebrand factor (VWF(R1326H)), we have developed a small animal model that supports human but not mouse platelet-mediated thrombosis. Here, we evaluate the use of this biological platform as a p...

journal_title：Circulation

authors： Magallon J,Chen J,Rabbani L,Dangas G,Yang J,Bussel J,Diacovo T

更新日期：2011-01-25 00:00:00

abstract：BACKGROUND:Hypercholesterolemia is a risk factor for coronary disease, and platelet reactivity is increased with hypercholesterolemia, suggesting a prethrombotic risk. The aim of this study was to measure mural platelet thrombus formation on an injured arterial wall in a model simulating vessel stenosis and plaque rupt...

journal_title：Circulation

authors： Lacoste L,Lam JY,Hung J,Letchacovski G,Solymoss CB,Waters D

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:The cytoskeleton plays an important role in maintaining cell structure and integrity. Defects in cytoskeletal proteins can cripple cell strength and may cause cardiomyopathy. We analyzed heart tissues from subjects with dilated cardiomyopathy for abnormalities in the cardiac cytoskeleton. Metavinculin, a car...

journal_title：Circulation

authors： Maeda M,Holder E,Lowes B,Valent S,Bies RD

更新日期：1997-01-07 00:00:00

abstract：BACKGROUND:Despite successful surgical correction, morbidity of patients with coarctation of the aorta is increased. It is well known that these patients have impaired elastic properties of the prestenotic arteries. To find out whether these abnormalities are primarily present or develop later, we studied 17 newborns b...

journal_title：Circulation

authors： Vogt M,Kühn A,Baumgartner D,Baumgartner C,Busch R,Kostolny M,Hess J

更新日期：2005-06-21 00:00:00

abstract：BACKGROUND:Thrombi are known to induce activation of the coagulation system, which may be a mechanism for progression of thrombosis and its recurrence after thrombolysis. This study was designed to characterize the relative role of thrombin and activated factor X (factor Xa) as mediators of procoagulant activity of who...

journal_title：Circulation

authors： Prager NA,Abendschein DR,McKenzie CR,Eisenberg PR

更新日期：1995-08-15 00:00:00

abstract：:All physicians increasingly will encounter patients who have implanted cardioverter-defibrillators (ICDs) for protection from ventricular arrhythmias. This advisory provides a concise summary relevant to the assessment and management of patients with ICDs, including those who present to primary care or emergency depar...

journal_title：Circulation

authors： Stevenson WG,Chaitman BR,Ellenbogen KA,Epstein AE,Gross WL,Hayes DL,Strickberger SA,Sweeney MO,Subcommittee on Electrocardiography and Arrhythmias of the American Heart Association Council on Clinical Cardiology.,Heart Rhythm Society.

更新日期：2004-12-21 00:00:00

abstract：BACKGROUND:CXCL16/SR-PSOX is an interferon-gamma-regulated chemokine and scavenger receptor for oxidized low-density lipoprotein that is expressed in atherosclerotic lesions. Proteolytic cleavage of membrane-bound CXCL16 releases soluble CXCL16, which may promote migration of effector T cells and augment a proatherogen...

journal_title：Circulation

authors： Jansson AM,Aukrust P,Ueland T,Smith C,Omland T,Hartford M,Caidahl K

更新日期：2009-06-30 00:00:00

abstract：BACKGROUND:Comprehensive data based on single-beat analysis of the ventricular activation sequence during sinus rhythm in infarcted hearts are currently not available. It was the aim of our study (1) to measure and analyze these activation sequences on the epicardial surface of the right and left ventricles and on the ...

journal_title：Circulation

authors： Hatala R,Savard P,Tremblay G,Pagé P,Cardinal R,Molin F,Kus T,Nadeau R

更新日期：1995-03-01 00:00:00

abstract：OBJECTIVES:To determine, using systematic review of the biomedical literature, whether pacing reduces risk of recurrent syncope and relevant clinical outcomes among adult patients with reflex-mediated syncope. METHODS:MEDLINE (through PubMed), EMBASE, and the Cochrane Central Register of Controlled Trials (through Oct...

journal_title：Circulation

authors： Varosy PD,Chen LY,Miller AL,Noseworthy PA,Slotwiner DJ,Thiruganasambandamoorthy V

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Transplant-associated coronary artery disease (TxCAD) is the manifestation of chronic rejection in the cardiac allograft. Both immunological and nonimmunological factors contribute to its development. Stratification by the time of development of TxCAD has not been considered previously for an extensive trans...

journal_title：Circulation

authors： Hornick P,Smith J,Pomerance A,Mitchell A,Banner N,Rose M,Yacoub M

更新日期：1997-11-04 00:00:00

abstract：BACKGROUND:The present study was designed to define the prevalence and characteristics of skeletal muscle alterations in patients with chronic heart failure (CHF) and their relation to exercise capacity. METHODS AND RESULTS:The ultrastructure of skeletal muscle was analyzed by ultrastructural morphometry in 57 patient...

journal_title：Circulation

authors： Drexler H,Riede U,Münzel T,König H,Funke E,Just H

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Patients with diabetes mellitus (DM) are at high risk of developing congestive heart failure (CHF). However, the relationships between glucose levels and CHF in people with or without a history of DM have not been well characterized. METHODS AND RESULTS:We evaluated the associations between fasting plasma g...

journal_title：Circulation

authors： Held C,Gerstein HC,Yusuf S,Zhao F,Hilbrich L,Anderson C,Sleight P,Teo K,ONTARGET\/TRANSCEND Investigators.

更新日期：2007-03-20 00:00:00

abstract：BACKGROUND:Elevated levels of oxidized phospholipids (OxPLs) on apolipoprotein B-100 particles (OxPL/apoB) are associated with cardiovascular disease and predict new cardiovascular events. Elevated lipoprotein (a) [Lp(a)] levels are a risk factor for cardiovascular disease in whites and also in blacks if they carry sma...

journal_title：Circulation

authors： Tsimikas S,Clopton P,Brilakis ES,Marcovina SM,Khera A,Miller ER,de Lemos JA,Witztum JL

更新日期：2009-04-07 00:00:00

abstract：BACKGROUND:While previous clinical studies have shown a possible beneficial effect of the reperfusion performed at a relatively late phase of acute myocardial infarction ("late reperfusion") in preventing left ventricular enlargement, the mechanism has not been clarified. METHODS AND RESULTS:Of 89 patients with an ini...

journal_title：Circulation

authors： Hirayama A,Adachi T,Asada S,Mishima M,Nanto S,Kusuoka H,Yamamoto K,Matsumura Y,Hori M,Inoue M

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Regional sympathetic denervation, such as that produced by a myocardial infarction, causes electrophysiological heterogeneity in the ventricles. The purpose of this study was to test the hypothesis that such denervation could cause drugs to exert heterogeneous myocardial effects. METHODS AND RESULTS:Sympath...

journal_title：Circulation

authors： Stanton MS,Zipes DP

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:Data on outcomes after Stanford type A aortic dissection in patients with Marfan syndrome are limited. We investigated the primary surgery and long-term results in patients with Marfan syndrome who suffered aortic dissection. METHODS AND RESULTS:Among 1324 consecutive patients with aortic dissection type A,...

journal_title：Circulation

authors： Rylski B,Bavaria JE,Beyersdorf F,Branchetti E,Desai ND,Milewski RK,Szeto WY,Vallabhajosyula P,Siepe M,Kari FA

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Although aspirin is an effective, inexpensive, and safe treatment of acute myocardial infarction, the frequency of use of aspirin in actual medical practice is not known. Elderly patients, a group with low rates of utilization of effective therapies such as thrombolytic therapy, also may be at risk of not re...

journal_title：Circulation

authors： Krumholz HM,Radford MJ,Ellerbeck EF,Hennen J,Meehan TP,Petrillo M,Wang Y,Kresowik TF,Jencks SF

更新日期：1995-11-15 00:00:00

abstract：:The pulmonary perfusion of 25 children who had total surgical correction of tetralogy of Fallot was evaluated by radionuclide perfusion scans. In addition, 18 had 133Xe ventilation studies. Eighteen of the children previously had palliative systemic-pulmonary shunts; 14 had aortic-pulmonary shunts (Waterston or Potts-...

journal_title：Circulation

authors： Alderson PO,Boonvisut S,McKnight RC,Hartman AF Jr

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:Myocardial perfusion reflects the macro- and microvascular coronary circulation. Recent quantitation developments using cardiovascular magnetic resonance perfusion permit automated measurement clinically. We explored the prognostic significance of stress myocardial blood flow (MBF) and myocardial perfusion r...

journal_title：Circulation

authors： Knott KD,Seraphim A,Augusto JB,Xue H,Chacko L,Aung N,Petersen SE,Cooper JA,Manisty C,Bhuva AN,Kotecha T,Bourantas CV,Davies RH,Brown LAE,Plein S,Fontana M,Kellman P,Moon JC

更新日期：2020-04-21 00:00:00

abstract：BACKGROUND:Oxidative stress activates endothelial innate immunity and disrupts endothelial functions, including endothelial nitric oxide synthase-derived nitric oxide bioavailability. Here, we postulated that oxidative stress induces sterol regulatory element-binding protein 2 (SREBP2) and microRNA-92a (miR-92a), which...

journal_title：Circulation

authors： Chen Z,Wen L,Martin M,Hsu CY,Fang L,Lin FM,Lin TY,Geary MJ,Geary GG,Zhao Y,Johnson DA,Chen JW,Lin SJ,Chien S,Huang HD,Miller YI,Huang PH,Shyy JY

更新日期：2015-03-03 00:00:00

abstract：:Trapidil (triazolopyrimidine) possesses activity against platelet-derived growth factor-induced cellular proliferation in vitro and intimal proliferation in vivo. The objective of this study was to determine if trapidil could prevent restenosis in experimentally induced atherosclerotic rabbits. New Zealand White rabbi...

journal_title：Circulation

authors： Liu MW,Roubin GS,Robinson KA,Black AJ,Hearn JA,Siegel RJ,King SB 3rd

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Cystic medial degeneration (CMD) is a histological abnormality that is common in the aortic diseases associated with Marfan's syndrome (MFS). Although little known about the mechanism underlying CMD, several recent reports have demonstrated that vascular smooth muscle cell (VSMC) apoptosis could play a subst...

journal_title：Circulation

authors： Nagashima H,Sakomura Y,Aoka Y,Uto K,Kameyama Ki,Ogawa M,Aomi S,Koyanagi H,Ishizuka N,Naruse M,Kawana M,Kasanuki H

更新日期：2001-09-18 00:00:00

abstract：BACKGROUND:Macrophages in human atherosclerotic plaques produce a family of matrix metalloproteinases (MMPs), which may influence vascular remodeling and plaque disruption. Because oxidized LDL (ox-LDL) is implicated in many proatherogenic events, we hypothesized that ox-LDL would regulate expression of MMP-9 and tissu...

journal_title：Circulation

authors： Xu XP,Meisel SR,Ong JM,Kaul S,Cercek B,Rajavashisth TB,Sharifi B,Shah PK

更新日期：1999-03-02 00:00:00

abstract：BACKGROUND:There is increasing evidence of a link between conduit vessel stiffness and cardiovascular events, although the association has never been tested in a large post-myocardial infarction patient population. METHODS AND RESULTS:We evaluated the relationship between baseline pulse pressure, measured by sphygmoma...

journal_title：Circulation

authors： Mitchell GF,Moyé LA,Braunwald E,Rouleau JL,Bernstein V,Geltman EM,Flaker GC,Pfeffer MA

更新日期：1997-12-16 00:00:00

abstract：:One of the noninvasive methods of evaluating left ventricular performance is the measurement of left ventricular systolic time intervals (LVSTI). However, noninvasive measurement of right ventricular systole by this technique has been unreliable because of the inability to accurately time the onset of right ventricula...

journal_title：Circulation

authors： Hirschfeld S,Meyer R,Schwartz DC,Korfhagen J,Kaplan S

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:The effects of carteolol, a nonselective beta-adrenergic receptor blocker with intrinsic sympathomimetic activity, were compared with those of metoprolol in a murine model of viral myocarditis and dilated cardiomyopathy caused by encephalomyocarditis virus. METHODS AND RESULTS:In the acute experiment, BALB/...

journal_title：Circulation

authors： Tominaga M,Matsumori A,Okada I,Yamada T,Kawai C

更新日期：1991-06-01 00:00:00

abstract：:The elimination of specific dietary cholesterol target recommendations in recent guidelines has raised questions about its role with respect to cardiovascular disease. This advisory was developed after a review of human studies on the relationship of dietary cholesterol with blood lipids, lipoproteins, and cardiovascu...

journal_title：Circulation

authors： Carson JAS,Lichtenstein AH,Anderson CAM,Appel LJ,Kris-Etherton PM,Meyer KA,Petersen K,Polonsky T,Van Horn L,American Heart Association Nutrition Committee of the Council on Lifestyle and Cardiometabolic Health; Council on Arteriosclero

更新日期：2020-01-21 00:00:00

abstract：BACKGROUND:Previous studies have documented the strong association between availability of on-site cardiac catheterization facilities and increased use of coronary angiography in patients with acute myocardial infarction (AMI). Although these studies have shown little influence of the availability of catheterization la...

journal_title：Circulation

authors： Every NR,Parsons LS,Fihn SD,Larson EB,Maynard C,Hallstrom AP,Martin JS,Weaver WD

更新日期：1997-09-16 00:00:00