Measurement of right and left ventricular systolic time intervals by echocardiography.

abstract：BACKGROUND:Subclinical inflammation is associated with an increased risk of heart failure and with adverse prognosis in patients with established heart failure. Yet, treatments specifically directed at reducing inflammation in patients with heart failure have not yet shown improved clinical outcomes. We tested the hypo...

journal_title：Circulation

authors： Everett BM,Cornel JH,Lainscak M,Anker SD,Abbate A,Thuren T,Libby P,Glynn RJ,Ridker PM

更新日期：2019-03-05 00:00:00

abstract：BACKGROUND:Radiofrequency catheter ablation is the treatment of choice for patients with paroxysmal supraventricular tachycardias refractory to medical therapy. However, in symptomatic patients with inappropriate sinus tachycardia resistant to drug therapy, catheter ablation of the His' bundle with permanent pacemaker ...

journal_title：Circulation

authors： Lee RJ,Kalman JM,Fitzpatrick AP,Epstein LM,Fisher WG,Olgin JE,Lesh MD,Scheinman MM

更新日期：1995-11-15 00:00:00

abstract：:Originally described by Japanese authors in the 1990s, Takotsubo syndrome (TTS) generally presents as an acute myocardial infarction characterized by severe left ventricular dysfunction. TTS, however, differs from an acute coronary syndrome because patients have generally a normal coronary angiogram and left ventricul...

journal_title：Circulation

authors： Pelliccia F,Kaski JC,Crea F,Camici PG

更新日期：2017-06-13 00:00:00

abstract：BACKGROUND:In patients with coronary artery disease (CAD), acute thrombosis frequently occurs in coronary arteries with only mild or moderate stenoses. Obesity increases the risk of atherosclerosis, but it is not known whether it also increases the risk of coronary thrombosis. We hypothesized that body mass index (BMI)...

journal_title：Circulation

authors： Wolk R,Berger P,Lennon RJ,Brilakis ES,Somers VK

更新日期：2003-11-04 00:00:00

abstract：BACKGROUND:Endogenous adenosine can protect the overloaded heart against the development of hypertrophy and heart failure, but the contribution of A(1) receptors (A(1)R) and A(3) receptors (A(3)R) is not known. METHODS AND RESULTS:To test the hypothesis that A(1)R and A(3)R can protect the heart against systolic overl...

journal_title：Circulation

authors： Lu Z,Fassett J,Xu X,Hu X,Zhu G,French J,Zhang P,Schnermann J,Bache RJ,Chen Y

更新日期：2008-10-21 00:00:00

abstract：BACKGROUND:Cardiac effects of hypertension include increased left ventricular (LV) mass and LV hypertrophy, as well as increased left atrial size, a predictor of stroke and atrial fibrillation. Although literature on reduction of LV mass with antihypertensive therapy is extensive, little information is available on eff...

journal_title：Circulation

authors： Gottdiener JS,Reda DJ,Williams DW,Materson BJ,Cushman W,Anderson RJ

更新日期：1998-07-14 00:00:00

abstract：BACKGROUND:We examined the relationship between hypertension subtype and cardiovascular disease incidence and mortality in Chinese adults. METHODS AND RESULTS:We conducted a prospective cohort study in a nationally representative sample of 169 871 Chinese men and women aged >or=40 years. Data on systolic (SBP) and dia...

journal_title：Circulation

authors： Kelly TN,Gu D,Chen J,Huang JF,Chen JC,Duan X,Wu X,Yau CL,Whelton PK,He J

更新日期：2008-10-07 00:00:00

abstract：BACKGROUND:Secretoneurin is a neuropeptide located in nerve fibers along blood vessels, is upregulated by hypoxia, and induces angiogenesis. We tested the hypothesis that secretoneurin gene therapy exerts beneficial effects in a rat model of myocardial infarction and evaluated the mechanism of action on coronary endoth...

journal_title：Circulation

authors： Albrecht-Schgoer K,Schgoer W,Holfeld J,Theurl M,Wiedemann D,Steger C,Gupta R,Semsroth S,Fischer-Colbrie R,Beer AG,Stanzl U,Huber E,Misener S,Dejaco D,Kishore R,Pachinger O,Grimm M,Bonaros N,Kirchmair R

更新日期：2012-11-20 00:00:00

abstract：BACKGROUND:Arterial hypertension is a prime cause of morbidity and mortality in the general population. Pharmacological treatment has limitations resulting from drug side effects, costs, and patient compliance. Thus, we investigated whether traditional Chinese medicine acupuncture is able to lower blood pressure. METH...

journal_title：Circulation

authors： Flachskampf FA,Gallasch J,Gefeller O,Gan J,Mao J,Pfahlberg AB,Wortmann A,Klinghammer L,Pflederer W,Daniel WG

更新日期：2007-06-19 00:00:00

abstract：:Three patients with total anomalous pulmonary venous drainage (TAPVD) into the innominate vein were studied by using M-mode and pulsed Doppler echocardiography. An abnormal continuous flow towards the transducer in a suprasternal notch position detected by pulsed Doppler echocardiography in the left hemithorax leftwar...

journal_title：Circulation

authors： Skovránek J,Tůma S,Urbancová D,Samánek M

更新日期：1980-04-01 00:00:00

abstract：:Atherosclerotic coronary artery disease is the major cause of late cardiac transplant failure secondary to silent ischemia and infarction. To increase the longevity of cardiac homografts, we performed percutaneous transluminal coronary angioplasty (PTCA) in five male patients (aged 45 +/- 7 years, mean +/- SEM); 17 le...

journal_title：Circulation

authors： Vetrovec GW,Cowley MJ,Newton CM,Lewis SA,DiSciascio G,Thompson JA,Hastillo A,Lower R,Hess M

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Cell-mediated autoimmunity has been strongly implicated in the pathogenesis of viral myocarditis. METHODS AND RESULTS:Using a murine model of acute myocarditis caused by coxsackievirus B3, we analyzed the phenotypes and morphology of the infiltrating cells in the hearts by immunofluorescence and electron mi...

journal_title：Circulation

authors： Seko Y,Shinkai Y,Kawasaki A,Yagita H,Okumura K,Takaku F,Yazaki Y

更新日期：1991-08-01 00:00:00

abstract：:The results of coronary bypass 5-10 years after operation at the Baylor College of Medicine are reported. The late results demonstrate that good relief of symptoms of angina pectoris persisted in 89% of patients at 10 years of follow-up. An overall annual attrition rate of 3% has been fairly constant through 10 years ...

journal_title：Circulation

authors： Lawrie GM,Morris GC Jr

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND:Transcatheter aortic valve replacement (TAVR) represents a paradigm shift in the therapeutic options for patients with severe aortic stenosis. However, rapid and exponential growth in TAVR demand may overwhelm capacity, translating to inadequate access and prolonged wait times. Our objective was to evaluate ...

journal_title：Circulation

authors： Elbaz-Greener G,Masih S,Fang J,Ko DT,Lauck SB,Webb JG,Nallamothu BK,Wijeysundera HC

更新日期：2018-07-31 00:00:00

abstract：BACKGROUND:Growth factors such as platelet-derived growth factor (PDGF) have been postulated to be important mediators of neointimal formation in balloon-injured artery. Binding of growth factors to their receptors activates intrinsic receptor tyrosine kinase, resulting in tyrosine phosphorylation of receptors themselv...

journal_title：Circulation

authors： Abe J,Deguchi J,Matsumoto T,Takuwa N,Noda M,Ohno M,Makuuchi M,Kurokawa K,Takuwa Y

更新日期：1997-09-16 00:00:00

abstract：BACKGROUND:We determined the intraclass correlation coefficients (ICC) of repeated measures of the mean levels and variability of RR and muscle sympathetic nerve activity (MSNA) in 7 normal subjects. We examined whether spontaneous fluctuations in RR and MSNA over repeated measurements were mirrored by changes in spect...

journal_title：Circulation

authors： van de Borne P,Montano N,Zimmerman B,Pagani M,Somers VK

更新日期：1997-12-16 00:00:00

abstract：BACKGROUND:Chlamydia pneumoniae stimulates chronic inflammation in vascular cells. Hydroxymethylglutaryl coenzyme A reductase inhibitors (statins) may have an ameliorating effect. We investigated possible mechanisms. METHODS AND RESULTS:We infected human macrophages that in coculture spread infection to vascular smoot...

journal_title：Circulation

authors： Dechend R,Gieffers J,Dietz R,Joerres A,Rupp J,Luft FC,Maass M

更新日期：2003-07-22 00:00:00

abstract：:Twelve consecutive patients who developed torsade de pointes (polymorphous ventricular tachycardia with marked QT prolongation, TdP) over a 4 year period were treated with intravenous injections of magnesium sulfate. In nine of the patients a single bolus of 2 g completely abolished the TdP within 1 to 5 min, and in t...

journal_title：Circulation

authors： Tzivoni D,Banai S,Schuger C,Benhorin J,Keren A,Gottlieb S,Stern S

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Factors leading differentially to the development of isolated diastolic (IDH), systolic-diastolic (SDH), and isolated systolic (ISH) hypertension are poorly understood. We examined the relations of blood pressure (BP) and clinical risk factors to the new onset of the 3 forms of hypertension. METHODS AND RES...

journal_title：Circulation

authors： Franklin SS,Pio JR,Wong ND,Larson MG,Leip EP,Vasan RS,Levy D

更新日期：2005-03-08 00:00:00

abstract：:Calcification of valvular bioprostheses in children is a major problem that has stimulated extensive research in our laboratory. In previous reports, we have shown that the rate of calcification could be reduced by decreasing the phosphate content in the tissue or by blocking calcification binding sites with Mg++ and/...

journal_title：Circulation

authors： Carpentier A,Nashef A,Carpentier S,Ahmed A,Goussef N

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:Alpha-linolenic acid may protect against cardiovascular disease. We examined the association between adipose tissue alpha-linolenic acid and nonfatal acute myocardial infarction (MI) in a population-based case-control study in Costa Rica. METHODS AND RESULTS:The 482 case patients with a first nonfatal acute...

journal_title：Circulation

authors： Baylin A,Kabagambe EK,Ascherio A,Spiegelman D,Campos H

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Early stages of coronary atherosclerosis are characterized by a mainly functional impairment of coronary vasodilator capacity under the impact of such risk factors as hypercholesterolemia. The goal of this study was to determine whether 6-month cholesterol-lowering therapy improves coronary flow reserve in p...

journal_title：Circulation

authors： Baller D,Notohamiprodjo G,Gleichmann U,Holzinger J,Weise R,Lehmann J

更新日期：1999-06-08 00:00:00

abstract：BACKGROUND:Sudden Unexplained Death Syndrome (SUDS) is the leading cause of death in young, healthy, Southeast Asian men. The role of an implantable cardioverter defibrillator (ICD) for mortality reduction in these patients remains unclear. METHODS AND RESULTS:The Defibrillator Versus beta-Blockers for Unexplained Dea...

journal_title：Circulation

authors： Nademanee K,Veerakul G,Mower M,Likittanasombat K,Krittayapong R,Bhuripanyo K,Sitthisook S,Chaothawee L,Lai MY,Azen SP

更新日期：2003-05-06 00:00:00

abstract：BACKGROUND:The contractile dysfunction observed in end-stage myocardial hypertrophy has at its base an abnormality in myocyte function. However, whether depressed contractile function is related to an alteration in contractile protein function is presently unknown. METHODS AND RESULTS:Contractile force, tension, and c...

journal_title：Circulation

authors： Fan D,Wannenburg T,de Tombe PP

更新日期：1997-05-06 00:00:00

abstract：:The effect of prolonged intense endurance exercise training on exertional hypotension was investigated in 16 patients with coronary artery disease who had a 10 mm Hg or greater fall in systolic blood pressure (SBP) during progressive exercise testing. Training consisted of walking, running, or cycling at 50% to 60% of...

journal_title：Circulation

authors： Martin WH 3rd,Ehsani AA

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:Recent studies have suggested that endogenous erythropoietin (Epo) plays an important role in the mobilization of bone marrow-derived endothelial progenitor cells (EPCs). However, it remains to be elucidated whether the Epo system exerts protective effects on pulmonary hypertension (PH), a fatal disorder enc...

journal_title：Circulation

authors： Satoh K,Kagaya Y,Nakano M,Ito Y,Ohta J,Tada H,Karibe A,Minegishi N,Suzuki N,Yamamoto M,Ono M,Watanabe J,Shirato K,Ishii N,Sugamura K,Shimokawa H

更新日期：2006-03-21 00:00:00

abstract：BACKGROUND:Coronary flow reserve (CFR), an integrated measure of focal, diffuse, and small-vessel coronary artery disease (CAD), identifies patients at risk for cardiac death. We sought to determine the association between CFR, angiographic CAD, and cardiovascular outcomes. METHODS AND RESULTS:Consecutive patients (n=...

journal_title：Circulation

authors： Taqueti VR,Hachamovitch R,Murthy VL,Naya M,Foster CR,Hainer J,Dorbala S,Blankstein R,Di Carli MF

更新日期：2015-01-06 00:00:00

abstract：:To determine the evolution of amyloid heart disease, 28 patients with familial amyloid polyneuropathy (FAP) were studied by echocardiography. The incidence and degree of the abnormalities were correlated with the neurologic disabilities, duration of the illness, and age in cross-sectional studies. Serial studies were ...

journal_title：Circulation

authors： Hongo M,Ikeda S

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:A warm-water bath (WWB) or sauna bath (SB) has generally been considered inappropriate for patients with severe congestive heart failure (CHF). However, a comprehensive investigation of the hemodynamic effects of thermal vasodilation in CHF has not been previously undertaken. METHODS AND RESULTS:To investig...

journal_title：Circulation

authors： Tei C,Horikiri Y,Park JC,Jeong JW,Chang KS,Toyama Y,Tanaka N

更新日期：1995-05-15 00:00:00

abstract：BACKGROUND:High-speed rotational atherectomy uses a diamond-coated, elliptical burr to abrade occlusive atherosclerosis, especially noncompliant calcified plaque. METHODS AND RESULTS:Intravascular ultrasound (IVUS) was used to analyze 28 patients after atherectomy. Arteries treated and imaged were left main (three), l...

journal_title：Circulation

authors： Mintz GS,Potkin BN,Keren G,Satler LF,Pichard AD,Kent KM,Popma JJ,Leon MB

更新日期：1992-11-01 00:00:00