Abstract:
:The effect of prolonged intense endurance exercise training on exertional hypotension was investigated in 16 patients with coronary artery disease who had a 10 mm Hg or greater fall in systolic blood pressure (SBP) during progressive exercise testing. Training consisted of walking, running, or cycling at 50% to 60% of peak oxygen uptake (peak VO2) for 30 min 3 days per week for an initial 3 months and was followed by an additional 9 months of similar exercise performed at 70% to 90% of peak VO2 for 50 to 60 min 5 days per week. The 1 year program resulted in a 41% increase in peak VO2 and lower heart rate and blood pressure responses to submaximal work. Before conditioning, SBP attained a maximal value of 162 +/- 5 mm Hg but fell 21 +/- 3 mm Hg, to 141 +/- 7 mm Hg, at peak effort (p less than .01). After training, maximal SBP was achieved at a faster heart rate (157 +/- 5 vs 132 +/- 6 beats/min; p less than .001) and was 7.4% higher (174 +/- 6 vs 162 +/- 5 mm Hg; p less than .005), while SBP at peak exercise had increased by 21% (171 +/- 6 vs 141 +/- 7 mm Hg; p less than .001) and ST segment depression was slightly reduced. Left ventricular ejection fraction (LVEF) before training declined from 56 +/- 4% at rest to 52 +/- 3% at peak exercise (p less than .05).(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Circulationjournal_title
Circulationauthors
Martin WH 3rd,Ehsani AAdoi
10.1161/01.cir.76.3.548subject
Has Abstractpub_date
1987-09-01 00:00:00pages
548-55issue
3eissn
0009-7322issn
1524-4539journal_volume
76pub_type
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