Short-term vasodilator effect of captopril in patients with severe mitral regurgitation is parasympathetically mediated.

abstract：:Mapping of blood velocities across the lumen of the ascending aorta was performed in eight patients during open-heart surgery. A Doppler ultrasound probe was constructed to measure velocities in 2 mm steps from the maximum convexity to the maximum concavity of aorta, 6 to 7 cm above the aortic valve. In five patients ...

journal_title：Circulation

authors： Segadal L,Matre K

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:Estrogen may increase the long-term survival of women who have suffered from a myocardial infarction (MI). We examined the acute and chronic influence of estrogen on MI in the rat left coronary artery ligation model. METHODS AND RESULTS:Female Sprague-Dawley rats (10 to 12 weeks, n=93), divided into 3 group...

journal_title：Circulation

authors： Smith PJ,Ornatsky O,Stewart DJ,Picard P,Dawood F,Wen WH,Liu PP,Webb DJ,Monge JC

更新日期：2000-12-12 00:00:00

abstract：BACKGROUND:Abnormalities in HDL and an increased risk of coronary artery disease (CAD) coexist in non-insulin-dependent diabetes mellitus (NIDDM). HDLs can be separated by their apolipoprotein (apo) content into particles containing apoA-I but not apoA-II (LpA-I) and those containing both apoA-I and apoA-II (LpA-I:A-II...

journal_title：Circulation

authors： Syvänne M,Kahri J,Virtanen KS,Taskinen MR

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Familial polymorphic ventricular tachycardia is an autosomal-dominant, inherited disease with a relatively early onset and a mortality rate of approximately 30% by the age of 30 years. Phenotypically, it is characterized by salvoes of bidirectional and polymorphic ventricular tachycardias in response to vigo...

journal_title：Circulation

authors： Laitinen PJ,Brown KM,Piippo K,Swan H,Devaney JM,Brahmbhatt B,Donarum EA,Marino M,Tiso N,Viitasalo M,Toivonen L,Stephan DA,Kontula K

更新日期：2001-01-30 00:00:00

abstract：BACKGROUND:The aim of this study was to prospectively test whether the risk of bleeding complications in 212 consecutive outpatients treated with oral anticoagulants could be predicted by levels of endothelium-derived hemostatic variables. METHODS AND RESULTS:All bleeding complications were recorded during 5 years of ...

journal_title：Circulation

authors： Jansson JH,Boman K,Brännström M,Nilsson TK

更新日期：1997-11-04 00:00:00

abstract：BACKGROUND:In patients with acute myocardial infarction (AMI), hyperglycemia predicts death, but the prognostic significance of hypoglycemia is controversial. METHODS AND RESULTS:We evaluated the prognostic significance of hypoglycemia and hyperglycemia in 30 536 AMI patients in a post hoc analysis of 2 large trials o...

journal_title：Circulation

authors： Goyal A,Mehta SR,Díaz R,Gerstein HC,Afzal R,Xavier D,Liu L,Pais P,Yusuf S

更新日期：2009-12-15 00:00:00

abstract：:We reviewed 35 patients undergoing resection of a chronic postinfarction left ventricular aneurysm. There was 5.7% operative mortality. Of the long-term survivors, 80% are functional class I or II. Ten patients had postoperative left ventriculograms studied by means of a computerized analysis of endocardial motion usi...

journal_title：Circulation

authors： Shaw RC,Connors JP,Hieb BR,Ludbrook PA,Krone R,Kleiger RE,Ferguson TB,Weldon CS

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:Thrombin plays a role in mediating ischemic injury and cardiac arrhythmias, but the mechanisms involved are poorly understood. Because voltage-gated sodium channels (VGSCs) have not previously been considered, putative effects of thrombin on VGSC function were investigated in human isolated cardiomyocytes. ...

journal_title：Circulation

authors： Pinet C,Le Grand B,John GW,Coulombe A

更新日期：2002-10-15 00:00:00

abstract：BACKGROUND:Cellular transplantation is emerging as a promising strategy for the treatment of postinfarction ventricular dysfunction. Whether its beneficial effects can be extended to other cardiomyopathies remains an unexplored question. We evaluated the histological and functional effects of simultaneous autologous tr...

journal_title：Circulation

authors： Guarita-Souza LC,Carvalho KA,Woitowicz V,Rebelatto C,Senegaglia A,Hansen P,Miyague N,Francisco JC,Olandoski M,Faria-Neto JR,Brofman P

更新日期：2006-07-04 00:00:00

abstract：BACKGROUND:Intracoronary radiotherapy (brachytherapy) has been proposed as treatment option for in-stent restenosis. Long-term results of brachytherapy with regard to vascular integrity and vasomotor responsiveness are unknown. The purpose of the present study was to determine the vasomotor response after brachytherapy...

journal_title：Circulation

authors： Togni M,Windecker S,Wenaweser P,Tueller D,Kaisaier A,Maier W,Meier B,Hess OM

更新日期：2004-07-13 00:00:00

abstract：BACKGROUND:Disintegrin metalloproteinases (ADAMs) may contribute to structural cardiac remodeling by altering cell-surface matrix receptors (integrins) and activating potent biomolecules. We compared expression of ADAMs, their endogenous inhibitor tissue inhibitor of metalloproteinases (TIMP)-3, and integrins in human ...

journal_title：Circulation

authors： Fedak PW,Moravec CS,McCarthy PM,Altamentova SM,Wong AP,Skrtic M,Verma S,Weisel RD,Li RK

更新日期：2006-01-17 00:00:00

abstract：BACKGROUND:Intracoronary stents may be effective when used as "bail-out" devices for acute complications after percutaneous transluminal coronary angioplasty. Furthermore, preliminary reports have demonstrated some promising results with stents with regard to the reduction of restenosis. Several stent devices are avail...

journal_title：Circulation

authors： van der Giessen WJ,Serruys PW,van Beusekom HM,van Woerkens LJ,van Loon H,Soei LK,Strauss BH,Beatt KJ,Verdouw PD

更新日期：1991-05-01 00:00:00

abstract：:A mathematical model to measure infarct size from serial estimates of CPK has been developed by Shell et al. Norris et al. have recently introduced a modification of this method by calculating an individualized disappearance rate parameter (Kd) from the uniformly monoexponential portion of the CPK vs time curve. This ...

journal_title：Circulation

authors： Slutsky AS

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND:Smooth muscle cell (SMC) migration and proliferation critically influence the clinical course of vascular disease. We tested the effect of the novel small leucine-rich repeat protein podocan on SMC migration and proliferation using a podocan-deficient mouse in combination with a model of arterial injury and ...

journal_title：Circulation

authors： Hutter R,Huang L,Speidl WS,Giannarelli C,Trubin P,Bauriedel G,Klotman ME,Fuster V,Badimon JJ,Klotman PE

更新日期：2013-11-26 00:00:00

abstract：BACKGROUND:Early risk assessment is important in patients with unstable coronary artery disease, ie, unstable angina or non-Q-wave myocardial infarction. Some previous small studies have indicated that patients with unstable angina and elevation of troponin T (tn-T) have worse short-term and long-term prognoses. In thi...

journal_title：Circulation

authors： Lindahl B,Venge P,Wallentin L

更新日期：1996-05-01 00:00:00

abstract：:Phasic blood flow recorded in five unobstructed dog aortocoronary bypass grafts to the left coronary artery was similar to that of normal coronary arteries, with a high diastolic-to-systolic flow ratio which averaged 2.7 +/- 0.4. With an average of 52 +/- 7% and 72 +/- 6% stenosis in the coronary artery distal to the ...

journal_title：Circulation

authors： Folts JD,Kahn DR,Bittar N,Rowe GG

更新日期：1975-08-01 00:00:00

abstract：:Between 1976 and 1982, 413 consecutive patients underwent valvular replacement with a bioprosthesis. Aortic valve replacement was performed in 240 patients, mitral valve replacement in 132, and multiple-valve replacement in 41. Four prostheses were employed: Carpentier-Edwards porcine (n = 336), Angel-Shiley porcine (...

journal_title：Circulation

authors： Teoh KH,Ivanov J,Weisel RD,Darcel IC,Rakowski H

更新日期：1989-09-01 00:00:00

abstract：:Cardiac allograft vasculopathy (CAV) remains a troublesome long-term complication of heart transplantation. It is manifested by a unique and unusually accelerated form of coronary disease affecting both intramural and epicardial coronary arteries and veins.CAV is characterized by vascular injury induced by a variety o...

journal_title：Circulation

authors： Weis M,von Scheidt W

更新日期：1997-09-16 00:00:00

abstract：:The relation between left atrial size and atrial fibrillation was examined in 37 patients who had left ventriculomyotomy and myectomy at the National Heart and Lung Institute. Atrial fibrillation was present in 11 of 27 (41%) patients with an echocardiographically measured left atrial dimension greater than 45 mm. No ...

journal_title：Circulation

authors： Watson DC,Henry WL,Epstein SE,Morrow AG

更新日期：1977-01-01 00:00:00

abstract：:To investigate whether ergonovine acts directly on coronary arteries or via remote neurohumoral reflexes, we administered small titrated increments of intracoronary ergonovine up to a maximum cumulative dose of 50 micrograms to 15 patients. In six patients with variant angina (group 1), ischemic electrocardiographic S...

journal_title：Circulation

authors： Hackett D,Larkin S,Chierchia S,Davies G,Kaski JC,Maseri A

更新日期：1987-03-01 00:00:00

abstract：:The goals of electrocardiographic (ECG) monitoring in hospital settings have expanded from simple heart rate and basic rhythm determination to the diagnosis of complex arrhythmias, myocardial ischemia, and prolonged QT interval. Whereas computerized arrhythmia analysis is automatic in cardiac monitoring systems, compu...

journal_title：Circulation

authors： Drew BJ,Califf RM,Funk M,Kaufman ES,Krucoff MW,Laks MM,Macfarlane PW,Sommargren C,Swiryn S,Van Hare GF,American Heart Association.,Councils on Cardiovascular Nursing, Clinical Cardiology, and Cardiovascular Disease in the Young.

更新日期：2004-10-26 00:00:00

abstract：:Subaortic stenosis is well known to complicate the clinical course of patients with single ventricle or univentricular hearts, and we have previously suggested that the development of subaortic stenosis in such patients may be causal to and/or accelerated by previous banding of the main pulmonary trunk. To further def...

journal_title：Circulation

authors： Freedom RM,Benson LN,Smallhorn JF,Williams WG,Trusler GA,Rowe RD

更新日期：1986-04-01 00:00:00

abstract：BACKGROUND:Outcomes after percutaneous coronary interventions in diabetic patients are shadowed by the increased rate of recurrence compared with nondiabetic patients. METHODS AND RESULTS:We conducted a multicenter, randomized trial to demonstrate the efficacy of sirolimus-eluting stents compared with standard stents ...

journal_title：Circulation

authors： Sabaté M,Jiménez-Quevedo P,Angiolillo DJ,Gómez-Hospital JA,Alfonso F,Hernández-Antolín R,Goicolea J,Bañuelos C,Escaned J,Moreno R,Fernández C,Fernández-Avilés F,Macaya C,DIABETES Investigators.

更新日期：2005-10-04 00:00:00

abstract：BACKGROUND:Dynamic intraventricular flow velocities after valve replacement for aortic stenosis have been associated with high in-hospital morbidity and mortality. The aims of the present study were to determine the mechanisms and preoperative predictors of abnormal flow velocity (AFV) after valve replacement for aorti...

journal_title：Circulation

authors： Bartunek J,Sys SU,Rodrigues AC,van Schuerbeeck E,Mortier L,de Bruyne B

更新日期：1996-02-15 00:00:00

abstract：BACKGROUND:Lung hypoplasia and persistent pulmonary hypertension of the newborn limit survival in congenital diaphragmatic hernia (CDH). Unlike other diseases resulting in persistent pulmonary hypertension of the newborn, infants with CDH are refractory to inhaled nitric oxide (NO). Nitric oxide mediates pulmonary vaso...

journal_title：Circulation

authors： Luong C,Rey-Perra J,Vadivel A,Gilmour G,Sauve Y,Koonen D,Walker D,Todd KG,Gressens P,Kassiri Z,Nadeem K,Morgan B,Eaton F,Dyck JR,Archer SL,Thébaud B

更新日期：2011-05-17 00:00:00

abstract：BACKGROUND:A complete understanding of fluid mechanics in Fontan physiology includes knowledge of the caval contributions to right (RPA) and left (LPA) pulmonary arterial blood flow, total systemic venous return, and relative blood flow to each lung. METHODS AND RESULTS:Ten Fontan patients underwent cine MRI. Three ci...

journal_title：Circulation

authors： Fogel MA,Weinberg PM,Rychik J,Hubbard A,Jacobs M,Spray TL,Haselgrove J

更新日期：1999-03-09 00:00:00

abstract：BACKGROUND:Impaired endothelium-dependent NO-mediated vasodilation is a key feature of essential hypertension and may precede the increase in blood pressure. We investigated whether transport of the NO precursor L-arginine is related to decreased endothelial function. METHODS AND RESULTS:Radiotracer kinetics ([3H]L-ar...

journal_title：Circulation

authors： Schlaich MP,Parnell MM,Ahlers BA,Finch S,Marshall T,Zhang WZ,Kaye DM

更新日期：2004-12-14 00:00:00

abstract：BACKGROUND:Serum uric acid (UA) could be a valid prognostic marker and useful for metabolic, hemodynamic, and functional (MFH) staging in chronic heart failure (CHF). METHODS AND RESULTS:For the derivation study, 112 patients with CHF (age 59+/-12 years, peak oxygen consumption [Vo2] 17+/-7 mL/kg per minute) were recr...

journal_title：Circulation

authors： Anker SD,Doehner W,Rauchhaus M,Sharma R,Francis D,Knosalla C,Davos CH,Cicoira M,Shamim W,Kemp M,Segal R,Osterziel KJ,Leyva F,Hetzer R,Ponikowski P,Coats AJ

更新日期：2003-04-22 00:00:00

abstract：BACKGROUND:The diagnosis of long QT syndrome (LQTS) is rather straightforward. We were surprised by realizing that, despite long-standing experience, we were making occasional diagnostic errors by considering as affected subjects who, over time, resulted as not affected. These individuals were all actively practicing s...

journal_title：Circulation

authors： Dagradi F,Spazzolini C,Castelletti S,Pedrazzini M,Kotta MC,Crotti L,Schwartz PJ

更新日期：2020-12-22 00:00:00

abstract：:This paper provides guidelines for the optimal, rather than minimal, performance of ultrasonic examination of the heart for current clinical applications using conventional echocardiographic equipment. Since the original report of this Inter-Society Commission on Heart Disease Resources Committee in 1975, M-mode echoc...

journal_title：Circulation

authors： Popp RL,Fortuin NJ,Johnson ML,Kisslo JA Jr

更新日期：1982-02-01 00:00:00