Effects of operation on left atrial size and the occurence of atrial fibrillation in patients with hypertrophic subaortic stenosis.

abstract：BACKGROUND:Heparin administration is usually limited to intravenous or subcutaneous injection. Oral delivery of heparin is an alternative to this and has been in great demand for treating patients who are at a high risk of deep vein thrombosis or pulmonary embolism. In this study, new heparin derivatives were synthesiz...

journal_title：Circulation

authors： Lee Y,Nam JH,Shin HC,Byun Y

更新日期：2001-12-18 00:00:00

abstract：BACKGROUND:The concept of natriuretic peptide guidance has been extensively studied in patients with chronic heart failure (HF), with only limited success. The effect of NT-proBNP (N-terminal probrain natriuretic peptide)-guided therapy in patients with acute decompensated HF using a relative NT-proBNP target has not b...

journal_title：Circulation

authors： Stienen S,Salah K,Moons AH,Bakx AL,van Pol P,Kortz RAM,Ferreira JP,Marques I,Schroeder-Tanka JM,Keijer JT,Bayés-Genis A,Tijssen JGP,Pinto YM,Kok WE

更新日期：2018-04-17 00:00:00

abstract：:High frequency notching of the QRS complex is associated with transmural infarction, cardiomyopathies, and ventricular hypertrophy from any cause. The mechanism producing notching is unknown; but the presence of a discrete anatomic lesion is not an essential feature. The hypothesis that notching was produced by activa...

journal_title：Circulation

authors： Vanderark CR,Reynolds EW

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:Xenografts ultimately fail as a result of acute vascular rejection (AVR), a process characterized by intravascular thrombosis, fibrin deposition, and endothelial cell activation. METHODS AND RESULTS:We studied whether targeted deletion of Fgl-2, an inducible endothelial cell procoagulant, (Fgl-2-/-) in the ...

journal_title：Circulation

authors： Mendicino M,Liu M,Ghanekar A,He W,Koscik C,Shalev I,Javadi M,Turnbull J,Chen W,Fung L,Sakamoto S,Marsden P,Waddell TK,Phillips MJ,Gorczynski R,Levy GA,Grant D

更新日期：2005-07-12 00:00:00

abstract：BACKGROUND:Tetralogy of Fallot is the most common form of congenital heart disease in implantable cardioverter-defibrillator (ICD) recipients, yet little is known about the value of ICDs in this patient population. METHODS AND RESULTS:We conducted a multicenter cohort study in high-risk patients with Tetralogy of Fall...

journal_title：Circulation

authors： Khairy P,Harris L,Landzberg MJ,Viswanathan S,Barlow A,Gatzoulis MA,Fernandes SM,Beauchesne L,Therrien J,Chetaille P,Gordon E,Vonder Muhll I,Cecchin F

更新日期：2008-01-22 00:00:00

abstract：:In 15 of 126 (12%) patients with truncus arteriosus who were catheterized at the Mayo Clinic from 1967 through 1975, natural agenesis of one pulmonary artery was present. Ten truncus patients with either natural or acquired absence of one pulmonary artery have undergone definitive operation. The criteria for operabili...

journal_title：Circulation

authors： Mair DD,Ritter DG,Danielson GK,Wallace RB,McGoon DC

更新日期：1977-04-01 00:00:00

abstract：BACKGROUND:In patients with acute myocardial infarction (AMI), hyperglycemia predicts death, but the prognostic significance of hypoglycemia is controversial. METHODS AND RESULTS:We evaluated the prognostic significance of hypoglycemia and hyperglycemia in 30 536 AMI patients in a post hoc analysis of 2 large trials o...

journal_title：Circulation

authors： Goyal A,Mehta SR,Díaz R,Gerstein HC,Afzal R,Xavier D,Liu L,Pais P,Yusuf S

更新日期：2009-12-15 00:00:00

abstract：:Cardiac allograft vasculopathy (CAV) remains a troublesome long-term complication of heart transplantation. It is manifested by a unique and unusually accelerated form of coronary disease affecting both intramural and epicardial coronary arteries and veins.CAV is characterized by vascular injury induced by a variety o...

journal_title：Circulation

authors： Weis M,von Scheidt W

更新日期：1997-09-16 00:00:00

abstract：BACKGROUND:The impact of cyclooxygenase (COX)-2 antagonist treatment on acute coronary risk is controversial. We investigated the effect of prolonged COX-2 inhibition on inflammatory profile and endothelial function in patients with ischemic heart disease and high serum C-reactive protein (CRP) values. METHODS AND RES...

journal_title：Circulation

authors： Bogaty P,Brophy JM,Noel M,Boyer L,Simard S,Bertrand F,Dagenais GR

更新日期：2004-08-24 00:00:00

abstract：BACKGROUND:Off-pump coronary artery bypass surgery (OPCAB) has been revived and has gained popularity, although the exact subsets of patients who might benefit most from this technique are unknown. The aim of this retrospective study was to compare the results of coronary artery bypass grafting surgery (CABG) in octoge...

journal_title：Circulation

authors： Demaria RG,Carrier M,Fortier S,Martineau R,Fortier A,Cartier R,Pellerin M,Hébert Y,Bouchard D,Pagé P,Perrault LP

更新日期：2002-09-24 00:00:00

abstract：BACKGROUND:A positive association was previously reported between angiotensin-converting enzyme (ACE) gene polymorphism and several cardiovascular diseases, such as myocardial infarction, left ventricular hypertrophy, and restenosis after percutaneous transluminal coronary angioplasty. Plasma ACE activity and carotid-w...

journal_title：Circulation

authors： Ishigami T,Umemura S,Iwamoto T,Tamura K,Hibi K,Yamaguchi S,Nyuui N,Kimura K,Miyazaki N,Ishii M

更新日期：1995-02-15 00:00:00

abstract：:Genetic analysis can be performed to identify the molecular substrate of inherited arrhythmogenic diseases; however, the role of this information in helping the management of patients is still debated. Here, we support the view that the practical value of genetic analysis is different in the various inherited conditio...

journal_title：Circulation

authors： Priori SG,Napolitano C

更新日期：2006-02-28 00:00:00

abstract：:The elevated blood pressure and vascular resistance in patients with systemic hypertension are paralleled by a proportional rise in pressure and resistance in the lesser circulation. We evaluated the hypothesis that the increased systemic reaction to adrenergic stimulation is shared by the pulmonary vessels. For this ...

journal_title：Circulation

authors： Guazzi MD,De Cesare N,Fiorentini C,Galli C,Moruzzi P,Tamborini G

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:The relationship of LPA single nucleotide polymorphisms (SNPs), apolipoprotein(a) isoforms, and lipoprotein(a) [Lp(a)] levels with major adverse cardiovascular events (MACE) in different ethnic groups is not well known. METHODS:LPA SNPs, apolipoprotein(a) isoforms, Lp(a), and oxidized phospholipids on apoli...

journal_title：Circulation

authors： Lee SR,Prasad A,Choi YS,Xing C,Clopton P,Witztum JL,Tsimikas S

更新日期：2017-01-17 00:00:00

abstract：BACKGROUND:Aortopulmonary collaterals (APC) have been associated with an increased risk of choreoathetosis after deep hypothermic circulatory arrest (DHCA). To study the effects of APC on cerebral hemodynamics and metabolism before and after DHCA, a piglet model was developed. METHODS AND RESULTS:Protocol 1: Eight 4- ...

journal_title：Circulation

authors： Kirshbom PM,Skaryak LA,DiBernardo LR,Kern FH,Greeley WJ,Gaynor JW,Ungerleider RM

更新日期：1995-11-01 00:00:00

abstract：:Adults are living longer, and cardiovascular disease is endemic in the growing population of older adults who are surviving into old age. Functional capacity is a key metric in this population, both for the perspective it provides on aggregate health and as a vital goal of care. Whereas cardiorespiratory function has ...

journal_title：Circulation

authors： Forman DE,Arena R,Boxer R,Dolansky MA,Eng JJ,Fleg JL,Haykowsky M,Jahangir A,Kaminsky LA,Kitzman DW,Lewis EF,Myers J,Reeves GR,Shen WK,American Heart Association Council on Clinical Cardiology; Council on Cardiovascular and St

更新日期：2017-04-18 00:00:00

abstract：BACKGROUND:It is recommended that comatose survivors of out-of-hospital cardiac arrest should be cooled to 32° to 34°C for 12 to 24 hours. However, the optimal level of cooling is unknown. The aim of this pilot study was to obtain initial data on the effect of different levels of hypothermia. We hypothesized that deepe...

journal_title：Circulation

authors： Lopez-de-Sa E,Rey JR,Armada E,Salinas P,Viana-Tejedor A,Espinosa-Garcia S,Martinez-Moreno M,Corral E,Lopez-Sendon J

更新日期：2012-12-11 00:00:00

abstract：:Analysis of the external brachial pulse recorded during standard blood pressure cuff deflation with use of a transducer with a wide frequency response has revealed a reproducible pattern with three distinct components that we have labeled K1, K2, and K3. K1 is a low-amplitude, low-frequency signal that is present with...

journal_title：Circulation

authors： Blank SG,West JE,Müller FB,Cody RJ,Harshfield GA,Pecker MS,Laragh JH,Pickering TG

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:Thrombin plays a role in mediating ischemic injury and cardiac arrhythmias, but the mechanisms involved are poorly understood. Because voltage-gated sodium channels (VGSCs) have not previously been considered, putative effects of thrombin on VGSC function were investigated in human isolated cardiomyocytes. ...

journal_title：Circulation

authors： Pinet C,Le Grand B,John GW,Coulombe A

更新日期：2002-10-15 00:00:00

abstract：BACKGROUND:Insulin sensitivity varies up to threefold in apparently healthy individuals, but the mechanism for this is unknown. We have examined the hypothesis that vascular endothelial nitric oxide production and insulin sensitivity are directly related in humans. METHODS AND RESULTS:Nineteen healthy male subjects we...

journal_title：Circulation

authors： Petrie JR,Ueda S,Webb DJ,Elliott HL,Connell JM

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Bolus thrombolytic therapy is a simplified means of administering thrombolysis that facilitates rapid time to treatment. TNK-tissue plasminogen activator (TNK-tPA) is a highly fibrin-specific single-bolus thrombolytic agent. METHODS AND RESULTS:In TIMI 10B, 886 patients with acute ST-elevation myocardial in...

journal_title：Circulation

authors： Cannon CP,Gibson CM,McCabe CH,Adgey AA,Schweiger MJ,Sequeira RF,Grollier G,Giugliano RP,Frey M,Mueller HS,Steingart RM,Weaver WD,Van de Werf F,Braunwald E

更新日期：1998-12-22 00:00:00

abstract：:Common conditions predisposing to atherosclerosis, such as hypercholesterolemia, hypertension, diabetes, and smoking, are associated with endothelial dysfunction. Endothelial function has largely been assessed as endothelium-dependent vasomotion, at least in part based on the assumption that impaired endothelium-depen...

journal_title：Circulation

authors： Landmesser U,Hornig B,Drexler H

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Previous studies suggested that blockade of RAGE in diabetic apolipoprotein (apo) E-null mice suppressed early acceleration of atherosclerosis. A critical test of the potential applicability of RAGE blockade to clinical settings was its ability to impact established vascular disease. In this study, we tested...

journal_title：Circulation

authors： Bucciarelli LG,Wendt T,Qu W,Lu Y,Lalla E,Rong LL,Goova MT,Moser B,Kislinger T,Lee DC,Kashyap Y,Stern DM,Schmidt AM

更新日期：2002-11-26 00:00:00

abstract：BACKGROUND:Swimming-induced pulmonary edema (SIPE) occurs during swimming or scuba diving, often in young individuals with no predisposing conditions, and its pathophysiology is poorly understood. This study tested the hypothesis that pulmonary artery and pulmonary artery wedge pressures are higher in SIPE-susceptible ...

journal_title：Circulation

authors： Moon RE,Martina SD,Peacher DF,Potter JF,Wester TE,Cherry AD,Natoli MJ,Otteni CE,Kernagis DN,White WD,Freiberger JJ

更新日期：2016-03-08 00:00:00

abstract：BACKGROUND:Recent data highlight a vital link between well-performed cardiopulmonary resuscitation (CPR) and survival after cardiac arrest; however, the quality of CPR as actually performed by trained healthcare providers is largely unknown. We sought to measure in-hospital chest compression rates and to determine comp...

journal_title：Circulation

authors： Abella BS,Sandbo N,Vassilatos P,Alvarado JP,O'Hearn N,Wigder HN,Hoffman P,Tynus K,Vanden Hoek TL,Becker LB

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Anisotropy creates nonuniformity in electrical propagation and may contribute to the occurrence of unidirectional conduction block and reentry. We describe the characteristics of reentrant tachycardia in a 2D layer of anisotropic ventricular myocardium. METHODS AND RESULTS:A Langendorff-perfused epicardial ...

journal_title：Circulation

authors： Schalij MJ,Boersma L,Huijberts M,Allessie MA

更新日期：2000-11-21 00:00:00

abstract：BACKGROUND:Endothelial nitric oxide (NO)-mediated responses are impaired in arterioles of male spontaneously hypertensive rats (SHR), but they are still present in female SHR. We hypothesized that in vitro incubation of arterioles of male SHR with estrogen will restore NO-mediated responses by upregulation of endotheli...

journal_title：Circulation

authors： Huang A,Sun D,Koller A,Kaley G

更新日期：2000-01-04 00:00:00

abstract：:The two new 99m (99mTc) labeled myocardial perfusion agents, 99mTc-Sestamibi and 99mTc-Teboroxime, are now available for routine clinical application. Both agents allow assessment of ejection fraction by the first-pass technique at rest or during exercise, thus providing additional information not available with thall...

journal_title：Circulation

authors： Berman DS,Kiat H,Maddahi J

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Reduced insulin sensitivity has been proposed as an important risk factor in the development of atherosclerosis. However, insulin sensitivity is related to many other cardiovascular risk factors, including plasma insulin levels, and it is unclear whether an independent role of insulin sensitivity exists. Lar...

journal_title：Circulation

authors： Howard G,O'Leary DH,Zaccaro D,Haffner S,Rewers M,Hamman R,Selby JV,Saad MF,Savage P,Bergman R

更新日期：1996-05-15 00:00:00

abstract：BACKGROUND:Ventricular tachyarrhythmias are the major clinical manifestation of arrhythmogenic right ventricular disease. Although antiarrhythmic therapy has been widely advocated, there is only limited information available on the efficacy of antiarrhythmic drugs in these patients. METHODS AND RESULTS:The short- and ...

journal_title：Circulation

authors： Wichter T,Borggrefe M,Haverkamp W,Chen X,Breithardt G

更新日期：1992-07-01 00:00:00