Intravascular ultrasound evaluation of the effect of rotational atherectomy in obstructive atherosclerotic coronary artery disease.

abstract：:Cardiovascular disease continues to be the leading cause of death among women in the United States. One of the barriers to improving cardiovascular disease outcomes in women is the lack of reliable, effective screening modalities. Breast arterial calcification has emerged as a potential risk stratification tool. Local...

journal_title：Circulation

authors： Bui QM,Daniels LB

更新日期：2019-02-19 00:00:00

abstract：BACKGROUND:Although intercellular adhesion molecule-1 (ICAM-1) is known to be expressed in balloon-injured arteries, it remains unknown whether ICAM-1 plays a role in the progression of intimal hyperplasia (IH) induced by balloon injury. METHODS AND RESULTS:We examined the ICAM-1 expression in rat carotid arteries at ...

journal_title：Circulation

authors： Yasukawa H,Imaizumi T,Matsuoka H,Nakashima A,Morimatsu M

更新日期：1997-03-18 00:00:00

abstract：:Sustained-release diltiazem (D-SR) and sustained-release verapamil (V-SR) when given twice a day have been successfully used to treat both essential hypertension and angina pectoris. Review of available studies indicates that 120 to 180 mg D-SR twice a day and 240 mg V-SR once or twice a day can lower diastolic pressu...

journal_title：Circulation

authors： Klein MD,Weiner DA

更新日期：1987-06-01 00:00:00

abstract：BACKGROUND:We evaluated the prognosis of deferred and revascularized coronary stenoses after fractional flow reserve (FFR) measurement to assess its revascularization threshold in clinical practice. METHODS:The IRIS-FFR registry (Interventional Cardiology Research In-cooperation Society Fractional Flow Reserve) prospe...

journal_title：Circulation

authors： Ahn JM,Park DW,Shin ES,Koo BK,Nam CW,Doh JH,Kim JH,Chae IH,Yoon JH,Her SH,Seung KB,Chung WY,Yoo SY,Lee JB,Choi SW,Park K,Hong TJ,Lee SY,Han M,Lee PH,Kang SJ,Lee SW,Kim YH,Lee CW,Park SW,Park SJ,IRIS-FF

更新日期：2017-06-06 00:00:00

abstract：:The acute hemodynamic effects of captopril were evaluated at cardiac catheterization in 16 children (age, 0.3-18 years) with cardiomyopathy. Twelve children had congestive cardiomyopathy, whereas four had restrictive cardiomyopathy. Hemodynamic measurements were obtained 30 and 60 minutes after the oral administration...

journal_title：Circulation

authors： Bengur AR,Beekman RH,Rocchini AP,Crowley DC,Schork MA,Rosenthal A

更新日期：1991-02-01 00:00:00

abstract：:Amiloride, a widely used diuretic, has multiple pharmacological actions, including inhibition of the sodium-hydronium ion and the sodium-calcium exchanger in heart. In terms of cardiac electrophysiology, amiloride prolongs action potential duration without alteration in upstroke velocity of phase 0 in Purkinje fibers....

journal_title：Circulation

authors： Duff HJ,Lester WM,Rahmberg M

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:Thrombus formation within a coronary vessel is the acute precipitating event in most acute coronary syndromes. Recently, constitutive nitric oxide synthase (cNOS) has been identified in human platelets, and platelet-derived nitric oxide has been shown to inhibit platelet recruitment after aggregation. Howeve...

journal_title：Circulation

authors： Freedman JE,Ting B,Hankin B,Loscalzo J,Keaney JF Jr,Vita JA

更新日期：1998-10-13 00:00:00

abstract：BACKGROUND:Epinephrine has been shown to impair pulmonary excretion of CO2 during resuscitation. This phenomenon was investigated in a rodent model of cardiac arrest and conventional resuscitation. METHODS AND RESULTS:The effects of racemic epinephrine were compared with the selective alpha 1-agonist methoxamine and w...

journal_title：Circulation

authors： Tang W,Weil MH,Gazmuri RJ,Sun S,Duggal C,Bisera J

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Recent data highlight a vital link between well-performed cardiopulmonary resuscitation (CPR) and survival after cardiac arrest; however, the quality of CPR as actually performed by trained healthcare providers is largely unknown. We sought to measure in-hospital chest compression rates and to determine comp...

journal_title：Circulation

authors： Abella BS,Sandbo N,Vassilatos P,Alvarado JP,O'Hearn N,Wigder HN,Hoffman P,Tynus K,Vanden Hoek TL,Becker LB

更新日期：2005-02-01 00:00:00

abstract：:Preservation of regional myocardial function, high-energy phosphate stores and ultrastructure were assessed in 28 canine hearts subjected to 2 hours of global ischemia at either 12 degrees C or 21 degrees C. The preservation achieved with a potassium arrest solution was simultaneously compared in the same heart with e...

journal_title：Circulation

authors： Johnson RG,Jacocks MA,Aretz TH,Geffin GA,O'Keefe DD,DeBoer LW,Guyton RA,Fallon JT,Daggett WM

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND:Although early intravenous beta-blocker therapy during acute myocardial infarction (AMI) reduces the incidence of fatal arrhythmias in patients not treated with thrombolytic agents, its antiarrhythmic effect in thrombolysed patients remains controversial. We investigated prospectively the arrhythmia incidenc...

journal_title：Circulation

authors： Heidbüchel H,Tack J,Vanneste L,Ballet A,Ector H,Van de Werf F

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Inhibition of fibrinolysis attributable to elevated concentrations of plasminogen activator inhibitor type 1 (PAI-1) in blood is associated with insulin resistance, hyperinsulinemia, and type 2 diabetes mellitus. Because we have shown that insulin can stimulate PAI-1 synthesis in vivo and because accelerated...

journal_title：Circulation

authors： Sobel BE,Woodcock-Mitchell J,Schneider DJ,Holt RE,Marutsuka K,Gold H

更新日期：1998-06-09 00:00:00

abstract：BACKGROUND:Administration of protease inhibitors (PIs) to HIV-infected individuals has been associated with hyperlipidemia. In this study, we characterized the lipoprotein profile in subjects receiving ritonavir, indinavir, or nelfinavir, alone or in combination with saquinavir. METHODS AND RESULTS:Plasma lipoprotein ...

journal_title：Circulation

authors： Périard D,Telenti A,Sudre P,Cheseaux JJ,Halfon P,Reymond MJ,Marcovina SM,Glauser MP,Nicod P,Darioli R,Mooser V

更新日期：1999-08-17 00:00:00

abstract：BACKGROUND:Isoprostanes (iPs) are free radical-catalyzed products of arachidonic acid that reflect lipid peroxidation in vivo. Several iPs exert biological effects in vitro and may contribute to the functional consequences of oxidant stress. For example, iPF(2alpha)-III (8-iso PGF(2alpha)) and iPE(2)-III modulate plate...

journal_title：Circulation

authors： Audoly LP,Rocca B,Fabre JE,Koller BH,Thomas D,Loeb AL,Coffman TM,FitzGerald GA

更新日期：2000-06-20 00:00:00

abstract：:Patients with heart failure frequently exhibit abnormal skeletal muscle metabolic responses to exercise, as assessed with 31P NMR. To investigate whether these metabolic abnormalities are due to intrinsic skeletal muscle changes, we performed gastrocnemius muscle biopsies on 22 patients with heart failure (peak VO2, 1...

journal_title：Circulation

authors： Mancini DM,Coyle E,Coggan A,Beltz J,Ferraro N,Montain S,Wilson JR

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Low-density lipoprotein (LDL) impairs endothelial cell function by uncoupling endothelial nitric oxide synthase (eNOS) activity, which allows superoxide anion (O2*-)) to be generated rather than nitric oxide (*NO). Recent reports indicate that apolipoprotein (apo) A-1 mimetics inhibit the development of athe...

journal_title：Circulation

authors： Ou Z,Ou J,Ackerman AW,Oldham KT,Pritchard KA Jr

更新日期：2003-03-25 00:00:00

abstract：BACKGROUND:The relative anti-aggregatory effects of currently prescribed platelet glycoprotein IIb/IIIa receptor antagonists during and after percutaneous coronary intervention for acute coronary syndromes have not been established. METHODS AND RESULTS:We randomized 70 acute coronary syndrome patients undergoing percu...

journal_title：Circulation

authors： Batchelor WB,Tolleson TR,Huang Y,Larsen RL,Mantell RM,Dillard P,Davidian M,Zhang D,Cantor WJ,Sketch MH Jr,Ohman EM,Zidar JP,Gretler D,DiBattiste PM,Tcheng JE,Califf RM,Harrington RA

更新日期：2002-09-17 00:00:00

abstract：BACKGROUND:Although a major role of coronary thrombosis in the pathogenesis of unstable angina has been demonstrated, the results of a series of studies have suggested that activation of the hemostatic system may not be confined to ischemic episodes. The purpose of this study was to investigate the temporal relation be...

journal_title：Circulation

authors： Biasucci LM,Liuzzo G,Caligiuri G,Quaranta G,Andreotti F,Sperti G,van de Greef W,Rebuzzi AG,Kluft C,Maseri A

更新日期：1996-06-15 00:00:00

abstract：BACKGROUND:Aortic counterpulsation has been observed to reduce the rate of reocclusion of the infarct-related artery after patency has been restored during acute myocardial infarction in observational studies. To evaluate the benefit-to-risk ratio of aortic counterpulsation during the early phase of myocardial infarcti...

journal_title：Circulation

authors： Ohman EM,George BS,White CJ,Kern MJ,Gurbel PA,Freedman RJ,Lundergan C,Hartmann JR,Talley JD,Frey MJ

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Serum uric acid (UA) could be a valid prognostic marker and useful for metabolic, hemodynamic, and functional (MFH) staging in chronic heart failure (CHF). METHODS AND RESULTS:For the derivation study, 112 patients with CHF (age 59+/-12 years, peak oxygen consumption [Vo2] 17+/-7 mL/kg per minute) were recr...

journal_title：Circulation

authors： Anker SD,Doehner W,Rauchhaus M,Sharma R,Francis D,Knosalla C,Davos CH,Cicoira M,Shamim W,Kemp M,Segal R,Osterziel KJ,Leyva F,Hetzer R,Ponikowski P,Coats AJ

更新日期：2003-04-22 00:00:00

abstract：BACKGROUND:The relationships between childhood lifestyle risk factors and adulthood pulse wave velocity (PWV) have not been reported. We studied whether childhood and adulthood lifestyle risk factors are associated with PWV assessed in adulthood. METHODS AND RESULTS:The study cohort comprised 1622 subjects of the Card...

journal_title：Circulation

authors： Aatola H,Koivistoinen T,Hutri-Kähönen N,Juonala M,Mikkilä V,Lehtimäki T,Viikari JS,Raitakari OT,Kähönen M

更新日期：2010-12-14 00:00:00

abstract：BACKGROUND:Aging is associated with increased cardiovascular risk and endothelial dysfunction. Since exercise can improve endothelium-dependent vasodilation, in the present study we tested whether long-term physical activity could prevent aging-related endothelial dysfunction. METHODS AND RESULTS:In 12 young and elder...

journal_title：Circulation

authors： Taddei S,Galetta F,Virdis A,Ghiadoni L,Salvetti G,Franzoni F,Giusti C,Salvetti A

更新日期：2000-06-27 00:00:00

abstract：BACKGROUND:Modeling of the time-[1-(11)C]acetate activity curve assumes a constant concentration of labeled tricarboxylic acid cycle intermediates and associated metabolites, such as glutamate and aspartate, which may, however, decrease in short-term hibernating myocardium. METHODS AND RESULTS:In 12 anesthetized pigs,...

journal_title：Circulation

authors： Schulz R,Kappeler C,Coenen H,Bockisch A,Heusch G

更新日期：1998-03-17 00:00:00

abstract：BACKGROUND:Beta-blockers improve clinical outcome when administered early after acute myocardial infarction. However, whether beta-blockers actually reduce the myocardial infarction size is still in dispute. Cardiac magnetic resonance imaging can accurately depict the left ventricular (LV) ischemic myocardium at risk (...

journal_title：Circulation

authors： Ibanez B,Prat-González S,Speidl WS,Vilahur G,Pinero A,Cimmino G,García MJ,Fuster V,Sanz J,Badimon JJ

更新日期：2007-06-12 00:00:00

abstract：BACKGROUND:Although there is a statistically significant association between modestly raised baseline plasma C-reactive protein (CRP) values and future cardiovascular events, the debate is still unsettled in regard to whether CRP plays a causal role in the pathogenesis of atherosclerosis. METHODS AND RESULTS:We genera...

journal_title：Circulation

authors： Koike T,Kitajima S,Yu Y,Nishijima K,Zhang J,Ozaki Y,Morimoto M,Watanabe T,Bhakdi S,Asada Y,Chen YE,Fan J

更新日期：2009-11-24 00:00:00

abstract：:Serial sections of the conduction system (CS) were performed in two patients with recurrent tachyarrhythmias. Case 1, a 34-year-old female who had dual atrioventricular (AV) nodal pathways with recurrent paroxysmal supraventricular tachycardia, committed suicide. Autopsy revealed an abnormally formed atrial septum wit...

journal_title：Circulation

authors： Bharati S,Bauernfiend R,Scheinman M,Massie B,Cheitlin M,Denes P,Wu D,Lev M,Rosen KM

更新日期：1979-03-01 00:00:00

abstract：BACKGROUND:The physiological assessment of angiographically intermediate-severity stenoses remains problematic. Functional measurements of poststenotic intracoronary Doppler coronary flow reserve can be performed in humans but have not been correlated with hyperemic myocardial perfusion imaging or angiographic data in ...

journal_title：Circulation

authors： Miller DD,Donohue TJ,Younis LT,Bach RG,Aguirre FV,Wittry MD,Goodgold HM,Chaitman BR,Kern MJ

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:The role of structural heart disease and sodium channel dysfunction in the induction of electrical instability in Brugada syndrome is still debated. METHODS AND RESULTS:We studied 18 consecutive patients (15 males, 3 females; mean age 42.0+/-12.4 years) with clinical phenotype of Brugada syndrome and normal...

journal_title：Circulation

authors： Frustaci A,Priori SG,Pieroni M,Chimenti C,Napolitano C,Rivolta I,Sanna T,Bellocci F,Russo MA

更新日期：2005-12-13 00:00:00

abstract：BACKGROUND:Leptin has been implicated in cardiovascular disease. A diet rich in fish has been associated with decreased cardiac and vascular risk. METHODS AND RESULTS:We examined the relationship between diet and leptin in 2 related homogeneous African tribal populations of Tanzania. One tribe consumes freshwater fish...

journal_title：Circulation

authors： Winnicki M,Somers VK,Accurso V,Phillips BG,Puato M,Palatini P,Pauletto P

更新日期：2002-07-16 00:00:00

abstract：BACKGROUND:Membrane contact sites are fundamental for transmission and translation of signals in multicellular organisms. The junctional membrane complexes in the cardiac dyads, where transverse (T) tubules are juxtaposed to the sarcoplasmic reticulum, are a prime example. T-tubule uncoupling and remodeling are well-kn...

journal_title：Circulation

authors： Liu C,Spinozzi S,Chen JY,Fang X,Feng W,Perkins G,Cattaneo P,Guimarães-Camboa N,Dalton ND,Peterson KL,Wu T,Ouyang K,Fu XD,Evans SM,Chen J

更新日期：2019-07-02 00:00:00