Positron emission tomography analysis of [1-(11)C] acetate kinetics in short-term hibernating myocardium.

abstract：:Neutrophil activation and infiltration into the ischemic myocardium after reperfusion may limit the amount of salvageable myocardium (reperfusion injury). The effects of intravenous perfluorochemicals (Fluosol-DA) on infarct size, ventricular contractility, and neutrophil function were assessed in an occlusion-reperfu...

journal_title：Circulation

authors： Bajaj AK,Cobb MA,Virmani R,Gay JC,Light RT,Forman MB

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Increased consumption of sugar-sweetened beverages (SSBs) has been associated with an elevated risk of obesity, metabolic syndrome, and type II diabetes mellitus. However, the effects of SSB consumption on blood pressure (BP) are uncertain. The objective of this study was to determine the relationship betwee...

journal_title：Circulation

authors： Chen L,Caballero B,Mitchell DC,Loria C,Lin PH,Champagne CM,Elmer PJ,Ard JD,Batch BC,Anderson CA,Appel LJ

更新日期：2010-06-08 00:00:00

abstract：BACKGROUND:Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) agonists inhibit vascular smooth muscle proliferation and migration and improve endothelial function. It is unknown whether PPAR-gamma agonists favorably modulate bone marrow (BM)-derived angiogenic progenitor cells (APCs) to promote endothelial l...

journal_title：Circulation

authors： Wang CH,Ciliberti N,Li SH,Szmitko PE,Weisel RD,Fedak PW,Al-Omran M,Cherng WJ,Li RK,Stanford WL,Verma S

更新日期：2004-03-23 00:00:00

abstract：BACKGROUND:The usefulness of adriamycin (ADR), a potent antitumor antibiotic, is limited by the development of life-threatening cardiomyopathy and congestive heart failure. Subcellular changes leading to heart failure are suggested to be mediated by a drug-induced increase in free radicals and lipid peroxidation. In an...

journal_title：Circulation

authors： Siveski-Iliskovic N,Hill M,Chow DA,Singal PK

更新日期：1995-01-01 00:00:00

abstract：:The pulmonary perfusion of 25 children who had total surgical correction of tetralogy of Fallot was evaluated by radionuclide perfusion scans. In addition, 18 had 133Xe ventilation studies. Eighteen of the children previously had palliative systemic-pulmonary shunts; 14 had aortic-pulmonary shunts (Waterston or Potts-...

journal_title：Circulation

authors： Alderson PO,Boonvisut S,McKnight RC,Hartman AF Jr

更新日期：1976-02-01 00:00:00

abstract：:Ten subjects with normal hemodynamics were studied during elective cardiac catheterization with right and left heart multisensor micromanometry to assess hemodynamic responses to the Mueller maneuver. Simultaneous right and left circulatory hemodynamics and left ventricular, pulmonary arterial, and aortic pressures we...

journal_title：Circulation

authors： Condos WR Jr,Latham RD,Hoadley SD,Pasipoularides A

更新日期：1987-11-01 00:00:00

abstract：:One hundred eighteen consecutive patients undergoing valve replacement for aortic stenosis were analyzed to determine the incidence of and predisposing factors to postoperative atrial tachyarrhythmias. Univariate and multivariate analyses were performed on 70 clinical, hemodynamic, radiographic, electrocardiographic, ...

journal_title：Circulation

authors： Douglas PS,Hirshfeld JW Jr,Edmunds LH Jr

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Previous studies found that percutaneous coronary intervention (PCI) does not improve outcome compared with medical therapy (MT) in patients with stable coronary artery disease, but PCI was guided by angiography alone. FAME 2 trial (Fractional Flow Reserve Versus Angiography for Multivessel Evaluation) compa...

journal_title：Circulation

authors： Fearon WF,Nishi T,De Bruyne B,Boothroyd DB,Barbato E,Tonino P,Jüni P,Pijls NHJ,Hlatky MA,FAME 2 Trial Investigators.

更新日期：2018-01-30 00:00:00

abstract：:We have studied the effects of cardioplegic solution (CS) on angiographic and histologic anatomy of bilateral vein grafts interposed into the carotid arteries of 10 dogs for up to 1 year. One vein (exp) was infused with cardioplegic solution (pH 7.7, K + 25 mEq/l, temperature 12 degrees C) every 15 min four times at p...

journal_title：Circulation

authors： Singh AK,Capone RJ,O'Shea P,Karlson KE

更新日期：1983-09-01 00:00:00

abstract：:It has been suggested that the beneficial effects of reperfusing ischemic myocardium might be in part reversed by the occurrence of "reperfusion injury." One possible mechanism could be the generation of oxygen free radicals. Superoxide dismutase enzymatically scavenges superoxide radicals by dismutation to hydrogen p...

journal_title：Circulation

authors： Ambrosio G,Weisfeldt ML,Jacobus WE,Flaherty JT

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Although metabolomic profiling offers promise for the prediction of coronary heart disease (CHD), and metabolic risk factors are more strongly associated with CHD in women than men, limited data are available for women. METHODS:We applied a liquid chromatography-tandem mass spectrometry metabolomics platfor...

journal_title：Circulation

authors： Paynter NP,Balasubramanian R,Giulianini F,Wang DD,Tinker LF,Gopal S,Deik AA,Bullock K,Pierce KA,Scott J,Martínez-González MA,Estruch R,Manson JE,Cook NR,Albert CM,Clish CB,Rexrode KM

更新日期：2018-02-20 00:00:00

abstract：:Twelve consecutive patients who developed torsade de pointes (polymorphous ventricular tachycardia with marked QT prolongation, TdP) over a 4 year period were treated with intravenous injections of magnesium sulfate. In nine of the patients a single bolus of 2 g completely abolished the TdP within 1 to 5 min, and in t...

journal_title：Circulation

authors： Tzivoni D,Banai S,Schuger C,Benhorin J,Keren A,Gottlieb S,Stern S

更新日期：1988-02-01 00:00:00

abstract：:The quantitative approaches to the assessment of regional left ventricular (LV) function described in the preceding paper were applied in a well-defined population of patients with coronary artery disease. Two groups were chosen by electrocardiographic and angiographic criteria: group 1 had infarction and regional wal...

journal_title：Circulation

authors： Parisi AF,Moynihan PF,Folland ED,Feldman CL

更新日期：1981-04-01 00:00:00

abstract：BACKGROUND:Elevated levels of oxidized phospholipids (OxPLs) on apolipoprotein B-100 particles (OxPL/apoB) are associated with cardiovascular disease and predict new cardiovascular events. Elevated lipoprotein (a) [Lp(a)] levels are a risk factor for cardiovascular disease in whites and also in blacks if they carry sma...

journal_title：Circulation

authors： Tsimikas S,Clopton P,Brilakis ES,Marcovina SM,Khera A,Miller ER,de Lemos JA,Witztum JL

更新日期：2009-04-07 00:00:00

abstract：BACKGROUND:Dual antiplatelet therapy with aspirin and a P2Y12 inhibitor has been shown to reduce the risk of major adverse cardiovascular events (MACE) compared with aspirin alone after percutaneous coronary intervention (PCI) or acute coronary syndrome but with increased risk of bleeding. The safety of discontinuing a...

journal_title：Circulation

authors： O'Donoghue ML,Murphy SA,Sabatine MS

更新日期：2020-08-11 00:00:00

abstract：BACKGROUND:We compared the efficacy and safety of different dosages of a low-molecular-weight heparin, CY 216 D (Fraxiparine), in the treatment of submassive pulmonary embolism with unfractionated heparin in a prospective, randomized, dose-finding study. METHODS AND RESULTS:The primary outcome was the evolution of pul...

journal_title：Circulation

authors： Théry C,Simonneau G,Meyer G,Hélénon O,Bridey F,Armagnac C,d'Azemar P,Coquart JP

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:It is well established that a depressed baroreflex sensitivity may adversely influence the prognosis in patients with chronic heart failure (CHF) and in those with previous myocardial infarction. METHODS AND RESULTS:We tested whether a slow breathing rate (6 breaths/min) could modify the baroreflex sensitiv...

journal_title：Circulation

authors： Bernardi L,Porta C,Spicuzza L,Bellwon J,Spadacini G,Frey AW,Yeung LY,Sanderson JE,Pedretti R,Tramarin R

更新日期：2002-01-15 00:00:00

abstract：BACKGROUND:Health-related quality-of-life instruments have become important measures of early health outcomes after cardiac surgery. The relationship between quality of life after recovery from surgery and subsequent long-term survival has not previously been explored. Our objective was to determine whether the Duke Ac...

journal_title：Circulation

authors： Koch CG,Li L,Lauer M,Sabik J,Starr NJ,Blackstone EH

更新日期：2007-02-13 00:00:00

abstract：BACKGROUND:Hypercholesterolemia and sickle cell disease (SCD) impair endothelium-dependent vasodilation by dissimilar mechanisms. Hypercholesterolemia impairs vasodilation by a low-density lipoprotein (LDL)-dependent mechanism. SCD has been characterized as a chronic state of inflammation in which xanthine oxidase (XO)...

journal_title：Circulation

authors： Ou J,Ou Z,Jones DW,Holzhauer S,Hatoum OA,Ackerman AW,Weihrauch DW,Gutterman DD,Guice K,Oldham KT,Hillery CA,Pritchard KA Jr

更新日期：2003-05-13 00:00:00

abstract：BACKGROUND:Excessive proliferation and apoptosis resistance of pulmonary artery smooth muscle cells (PASMCs) are key mechanisms of pulmonary arterial hypertension (PAH). Despite the multiple combination therapy, a considerable number of patients develop severe pulmonary hypertension (PH) because of the lack of diagnost...

journal_title：Circulation

authors： Kikuchi N,Satoh K,Kurosawa R,Yaoita N,Elias-Al-Mamun M,Siddique MAH,Omura J,Satoh T,Nogi M,Sunamura S,Miyata S,Saito Y,Hoshikawa Y,Okada Y,Shimokawa H

更新日期：2018-08-07 00:00:00

abstract：OBJECTIVE:To assess the outcome of 3 different surgical approaches for treatment of acute aortic dissection type A (AADA). METHODS AND RESULTS:Between October 1990 and October 2003, we operated on 295 patients (pts) for AADA. Follow-up was complete for 257 pts (87%). Supracommissural replacement (SCR) of the ascending...

journal_title：Circulation

authors： Kallenbach K,Oelze T,Salcher R,Hagl C,Karck M,Leyh RG,Haverich A

更新日期：2004-09-14 00:00:00

abstract：BACKGROUND:Cardiopulmonary resuscitation (CPR) is initiated in hospitalized children with bradycardia and poor perfusion. However, their rate of progression to pulseless cardiac arrest despite CPR and the differences in survival compared with initially pulseless arrest are unknown. We examined the prevalence and predic...

journal_title：Circulation

authors： Khera R,Tang Y,Girotra S,Nadkarni VM,Link MS,Raymond TT,Guerguerian AM,Berg RA,Chan PS,American Heart Association’s Get With the Guidelines-Resuscitation Investigators.

更新日期：2019-07-30 00:00:00

abstract：BACKGROUND:Sudden Unexplained Death Syndrome (SUDS) is the leading cause of death in young, healthy, Southeast Asian men. The role of an implantable cardioverter defibrillator (ICD) for mortality reduction in these patients remains unclear. METHODS AND RESULTS:The Defibrillator Versus beta-Blockers for Unexplained Dea...

journal_title：Circulation

authors： Nademanee K,Veerakul G,Mower M,Likittanasombat K,Krittayapong R,Bhuripanyo K,Sitthisook S,Chaothawee L,Lai MY,Azen SP

更新日期：2003-05-06 00:00:00

abstract：BACKGROUND:Despite a recent American Heart Association (AHA) consensus statement emphasizing the importance of resistant hypertension, the incidence and prognosis of this condition are largely unknown. METHODS AND RESULTS:This retrospective cohort study in 2 integrated health plans included patients with incident hype...

journal_title：Circulation

authors： Daugherty SL,Powers JD,Magid DJ,Tavel HM,Masoudi FA,Margolis KL,O'Connor PJ,Selby JV,Ho PM

更新日期：2012-04-03 00:00:00

abstract：BACKGROUND:Previous studies suggest that rigid fixation of the mitral annulus with an annuloplasty ring may impair left ventricular (LV) systolic performance. We used load-insensitive indexes of global and regional LV contractile mechanics to test the hypothesis that rigid fixation of the mitral annulus alters LV systo...

journal_title：Circulation

authors： Rayhill SC,Castro LJ,Nizyporuk MA,Ingels NB Jr,Daughters GT,Derby GC,Tye TL,Bolger AF,Miller DC

更新日期：1992-11-01 00:00:00

abstract：:Forty adult patients underwent Doppler and two-dimensional echocardiographic examination of the pulmonary artery from multiple views to determine the variability in the magnitude of Doppler-determined flow velocity and pulmonary arterial diameter from various echocardiographic windows. Flows were recorded from two or ...

journal_title：Circulation

authors： Lighty GW Jr,Gargiulo A,Kronzon I,Politzer F

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Fortilin, a recently characterized nuclear antiapoptotic factor structurally distinct from inhibitor of apoptosis proteins (IAPs) and Bcl-2 family member proteins, has been suggested to be involved in cell survival and regulation of apoptosis within the cardiovascular system. In this continued investigation,...

journal_title：Circulation

authors： Tulis DA,Mnjoyan ZH,Schiesser RL,Shelat HS,Evans AJ,Zoldhelyi P,Fujise K

更新日期：2003-01-07 00:00:00

abstract：BACKGROUND:The Ross procedure and aortic homografts have both been shown to have superior hemodynamic performance after valve replacement, but there have been few comparisons. METHODS:Sequential Doppler echocardiograms were performed up to 5 years after aortic valve replacement in 132 patients with the Ross procedure ...

journal_title：Circulation

authors： Laforest I,Dumesnil JG,Briand M,Cartier PC,Pibarot P

更新日期：2002-09-24 00:00:00

abstract：:The effects of abrupt withdrawal or continuation of beta-blockade therapy during acute myocardial infarction were evaluated in 326 patients participating in the Multicenter Investigation of the Limitation of Infarct Size (MILIS). Thirty-nine patients previously receiving a beta-blocker and randomly selected for withdr...

journal_title：Circulation

authors： Croft CH,Rude RE,Gustafson N,Stone PH,Poole WK,Roberts R,Strauss HW,Raabe DS Jr,Thomas LJ,Jaffe AS

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:Endothelial nitric oxide (NO)-mediated responses are impaired in arterioles of male spontaneously hypertensive rats (SHR), but they are still present in female SHR. We hypothesized that in vitro incubation of arterioles of male SHR with estrogen will restore NO-mediated responses by upregulation of endotheli...

journal_title：Circulation

authors： Huang A,Sun D,Koller A,Kaley G

更新日期：2000-01-04 00:00:00