Increased plasminogen activator inhibitor type 1 in coronary artery atherectomy specimens from type 2 diabetic compared with nondiabetic patients: a potential factor predisposing to thrombosis and its persistence.

abstract：:Vasodilatory or vasoconstrictive renal pharmacoangiography was applied in investigating the significance of 50 renal artery stenoses. The technique involves comparison of selective magnification renal arteriograms before and after intra-arterial injection of epinephrine or acetylcholine, seeking changes in direction o...

journal_title：Circulation

authors： Bookstein JJ,Walter JF,Stanley JC,Fry WJ

更新日期：1976-08-01 00:00:00

abstract：:To elucidate the mechanism of regional hemostasis in the left ventricular (LV) cavity during myocardial infarction, the blood pathway in LV cavity was examined with contrast echocardiography injected from the left atrium before and after coronary ligation in nine canines. Before coronary ligation, contrast echoes spre...

journal_title：Circulation

authors： Beppu S,Izumi S,Miyatake K,Nagata S,Park YD,Sakakibara H,Nimura Y

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Familial hypercholesterolemia (FH), an autosomal codominant disease, is characterized by high levels of LDL cholesterol and a high incidence of coronary artery disease (CAD). To date, genetic heterogeneity has hindered the proper assessment of the relation between risk factors and CAD in FH patients. METHOD...

journal_title：Circulation

authors： Ferrières J,Lambert J,Lussier-Cacan S,Davignon J

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Endothelin (ET), a coronary vasoconstrictor, mediates its activity through the specific receptors ET-A and ET-B, which may demonstrate different activity under pathophysiological conditions. Thoracic inferior vena cava constriction (TIVCC) is an experimental model of congestive heart failure that is characte...

journal_title：Circulation

authors： Cannan CR,Burnett JC Jr,Lerman A

更新日期：1996-02-15 00:00:00

abstract：BACKGROUND:Bronchopulmonary dysplasia (BPD) and pulmonary emphysema, both significant global health problems, are characterized by a loss of alveoli. Vascular endothelial growth factor (VEGF) is a trophic factor required for endothelial cell survival and is abundantly expressed in the lung. METHODS AND RESULTS:We repo...

journal_title：Circulation

authors： Thébaud B,Ladha F,Michelakis ED,Sawicka M,Thurston G,Eaton F,Hashimoto K,Harry G,Haromy A,Korbutt G,Archer SL

更新日期：2005-10-18 00:00:00

abstract：BACKGROUND:Peroxisome proliferator-activated receptors (PPARs) are transcription factors of the nuclear receptor superfamily. It has been reported that the thiazolidinediones, which are antidiabetic agents and high-affinity ligands for PPARgamma, regulate growth of vascular cells. In the present study, we examined the ...

journal_title：Circulation

authors： Asakawa M,Takano H,Nagai T,Uozumi H,Hasegawa H,Kubota N,Saito T,Masuda Y,Kadowaki T,Komuro I

更新日期：2002-03-12 00:00:00

abstract：BACKGROUND:Patients with primary amyloidosis (AL type) have a poor prognosis, in part due to frequent cardiac involvement. Although intracardiac thrombus has been reported in anecdotal cases, neither its frequency nor its role in causing mortality is known. Furthermore, the clinical and echocardiographic variables that...

journal_title：Circulation

authors： Feng D,Edwards WD,Oh JK,Chandrasekaran K,Grogan M,Martinez MW,Syed IS,Hughes DA,Lust JA,Jaffe AS,Gertz MA,Klarich KW

更新日期：2007-11-20 00:00:00

abstract：:Defibrillation/cardioversion thresholds were measured in 33 patients undergoing defibrillator implants. Each patient had a 12 cm2 patch placed near the left ventricular apex via a thoracotomy and a 10 cm2 spring lead placed pervenously at the right atrial-superior vena caval junction. Ventricular tachycardia of stable...

journal_title：Circulation

authors： Winkle RA,Stinson EB,Bach SM Jr,Echt DS,Oyer P,Armstrong K

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:Microvascular dysfunction posttreatment of stroke with recombinant human tissue-type plasminogen activator (rht-PA) constrains the therapeutic window to 3 hours. Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) promote vascular thrombolysis and reduce the inflammation response. We therefo...

journal_title：Circulation

authors： Zhang L,Zhang ZG,Ding GL,Jiang Q,Liu X,Meng H,Hozeska A,Zhang C,Li L,Morris D,Zhang RL,Lu M,Chopp M

更新日期：2005-11-29 00:00:00

abstract：:One thousand four Medtronic Hall valves (601 mitral, 398 aortic, and five tricuspid) were implanted in 847 patients between December 1979 and June 1987. Total experience at the end of June 1987 was 2,640 patient-years of follow-up. Prothrombin time ratios were reviewed for all patients (16,866 observations), and these...

journal_title：Circulation

authors： Butchart EG,Lewis PA,Grunkemeier GL,Kulatilake N,Breckenridge IM

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:We previously found in a pig coronary balloon injury model that vitamins C and E as well as probucol had beneficial effects on the vessel response to injury measured by morphometry These effects correlated with an inhibition in the ability to oxidize LDLs ex vivo, suggesting that the morphological response w...

journal_title：Circulation

authors： Nunes GL,Robinson K,Kalynych A,King SB 3rd,Sgoutas DS,Berk BC

更新日期：1997-11-18 00:00:00

abstract：:Cardiac events of early diastole were studied in 50 normal subjects and 46 patients with mitral stenosis (MS) by simultaneous recordings of the mitral valve echogram (MVE), phonocardiogram, and apexcardiogram (ACG). Left ventricular isovolumic relaxation time (IRT), measured between A2 and onset of the MVE opening mot...

journal_title：Circulation

authors： Toutouzas P,Velimezis A,Castellanos S,Avgoustakis D

更新日期：1978-04-01 00:00:00

abstract：BACKGROUND:Immunization with cardiac myosin induces experimental autoimmune heart disease in genetically predisposed mice. These mice produce heart-specific autoantibodies, some of which are directed against the cardiac myosin isoform. METHODS AND RESULTS:We have reported the presence of circulating heart-specific aut...

journal_title：Circulation

authors： Caforio AL,Grazzini M,Mann JM,Keeling PJ,Bottazzo GF,McKenna WJ,Schiaffino S

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:No information is available on the long-term results of radial artery (RA) grafts used as coronary artery bypass conduits. METHODS AND RESULTS:In this report, we describe the long-term (105+/-9 months) angiographic results of a series of 90 consecutive patients in whom the RA was used as a coronary artery b...

journal_title：Circulation

authors： Possati G,Gaudino M,Prati F,Alessandrini F,Trani C,Glieca F,Mazzari MA,Luciani N,Schiavoni G

更新日期：2003-09-16 00:00:00

abstract：BACKGROUND:Prolonged survival of xenografted neonatal cardiomyocytes was achieved by blocking the CD28/B7 costimulatory pathway via CTLA4-Ig gene transfer. We examined the long-term survival of xenografted neonatal cardiomyocytes by adenovirus-mediated CTLA4-Ig expression and transient CD40 blockade with anti-CD40L mon...

journal_title：Circulation

authors： Li TS,Ito H,Kajiwara K,Hamano K

更新日期：2003-10-07 00:00:00

abstract：BACKGROUND:Considerable controversy exists on the association between coffee consumption and cardiovascular disease (CVD) risk. A meta-analysis was performed to assess the dose-response relationship of long-term coffee consumption with CVD risk. METHODS AND RESULTS:PubMed and EMBASE were searched for prospective cohor...

journal_title：Circulation

authors： Ding M,Bhupathiraju SN,Satija A,van Dam RM,Hu FB

更新日期：2014-02-11 00:00:00

abstract：BACKGROUND:Atherosclerosis is a multifactorial disease in which inflammatory processes play an important role. Inflammation underlies lesion evolution at all stages, from establishment to plaque rupture and thrombosis. Costimulatory molecules of the tumor necrosis factor superfamily such as CD40/CD40L and OX40/OX40L ha...

journal_title：Circulation

authors： Olofsson PS,Söderström LA,Wågsäter D,Sheikine Y,Ocaya P,Lang F,Rabu C,Chen L,Rudling M,Aukrust P,Hedin U,Paulsson-Berne G,Sirsjö A,Hansson GK

更新日期：2008-03-11 00:00:00

abstract：BACKGROUND:Paroxysmal atrial fibrillation (AF) naturally progresses toward chronic AF at an estimated rate of 15% to 30% over a 1- to 3-year period. Pulmonary vein (PV) isolation is increasingly performed for the treatment of drug-refractory paroxysmal AF. The long-term data on clinical outcome after circumferential PV...

journal_title：Circulation

authors： Ouyang F,Tilz R,Chun J,Schmidt B,Wissner E,Zerm T,Neven K,Köktürk B,Konstantinidou M,Metzner A,Fuernkranz A,Kuck KH

更新日期：2010-12-07 00:00:00

abstract：:To describe the coronary arteriographic findings during early transmural myocardial infarction and to define the prevalence of coronary thrombosis by arteriography, we performed coronary arteriography and left ventriculography within 24 hours from symptom onset of transmural myocardial infarction in 517 patients. The ...

journal_title：Circulation

authors： DeWood MA,Spores J,Hensley GR,Simpson CS,Eugster GS,Sutherland KI,Grunwald RP,Shields JP

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:Transplant-associated coronary artery disease (TxCAD) is the manifestation of chronic rejection in the cardiac allograft. Both immunological and nonimmunological factors contribute to its development. Stratification by the time of development of TxCAD has not been considered previously for an extensive trans...

journal_title：Circulation

authors： Hornick P,Smith J,Pomerance A,Mitchell A,Banner N,Rose M,Yacoub M

更新日期：1997-11-04 00:00:00

abstract：BACKGROUND:Propylthiouracil (PTU) is used to treat hyperthyroid patients by its hypothyroid effect. PTU also is found to have potent antioxidant and immunosuppressive effects. These findings suggest that PTU may play a role in the prevention of atherosclerosis. METHODS AND RESULTS:This study evaluates the effect of PT...

journal_title：Circulation

authors： Chen WJ,Lin KH,Lai YJ,Yang SH,Pang JH

更新日期：2004-09-07 00:00:00

abstract：BACKGROUND:The pathogenesis of impaired endothelium-dependent coronary vasodilation in angina pectoris and normal coronary arteriograms (microvascular angina pectoris) is not known. We examined whether supplementation with L-arginine, a precursor of endothelium-derived nitric oxide, improves endothelium-dependent coron...

journal_title：Circulation

authors： Egashira K,Hirooka Y,Kuga T,Mohri M,Takeshita A

更新日期：1996-07-15 00:00:00

abstract：BACKGROUND:In essential hypertension, endothelium-dependent vasodilation is impaired because of reduced nitric oxide (NO) availability, which is mainly caused by oxidative stress. The present study was designed to identify the mechanism(s) responsible for NO-independent vasodilation to bradykinin in patients with essen...

journal_title：Circulation

authors： Taddei S,Ghiadoni L,Virdis A,Buralli S,Salvetti A

更新日期：1999-09-28 00:00:00

abstract：:We examined the cardiopulmonary effects of maximum bicycle ergometer exercise in seven patients with implanted Intermedics Nova MR pacemakers for three types of pacing in a randomized sequence: VVI or AAI at 70 beats/min (SSI 70), rate-adaptive temperature-controlled pacing with the implanted Nova MR, and rate-adaptiv...

journal_title：Circulation

authors： Alt E,Völker R,Högl B,MacCarter D

更新日期：1988-11-01 00:00:00

abstract：:Two-dimensional suprasternal notch echocardiography was performed in 1033 patients, ages 1 day to 18 years. For the long-axis suprasternal notch view, the transducer was positioned in the suprasternal notch and angled to obtain a plane passing between the right nipple and left scapular tip. In this view, the entire ao...

journal_title：Circulation

authors： Snider AR,Silverman NH

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Several methods have been developed to improve the efficacy of mechanical resuscitation, because organ perfusion achieved with conventional manual resuscitation is often insufficient. In animal studies, phased chest and abdominal compression-decompression resuscitation by use of the Lifestick device has resu...

journal_title：Circulation

authors： Arntz HR,Agrawal R,Richter H,Schmidt S,Rescheleit T,Menges M,Burbach H,Schröder J,Schultheiss HP

更新日期：2001-08-14 00:00:00

abstract：BACKGROUND:Since the atria are thin-walled structures, most studies that have examined the spread of activation in the atria have assumed that they behave electrophysiologically as a two-dimensional surface. It was the objective of this study to determine whether or not this assumption is true by simultaneously mapping...

journal_title：Circulation

authors： Schuessler RB,Kawamoto T,Hand DE,Mitsuno M,Bromberg BI,Cox JL,Boineau JP

更新日期：1993-07-01 00:00:00

abstract：:While the steady-state effects of positive pleural pressure on the circulation have been extensively studied, less is known about the immediate effects of positive intrathoracic pressure on cardiac dynamics. Therefore, we performed electrocardiographically gated radionuclide ventriculography with a respiratory gating ...

journal_title：Circulation

authors： Natarajan TK,Wise RA,Karam M,Permutt S,Wagner HN Jr

更新日期：1987-01-01 00:00:00

abstract：:In this paper we examine the relationship between risk factors and angiographically determined coronary artery disease for blacks and whites enrolled in the Coronary Artery Surgery Study (CASS). Analysis of data from the CASS registry indicated that blacks had a higher incidence of hypertension and current cigarette s...

journal_title：Circulation

authors： Maynard C,Fisher LD,Passamani ER,Pullum T

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:Cellular transplantation is emerging as a promising strategy for the treatment of postinfarction ventricular dysfunction. Whether its beneficial effects can be extended to other cardiomyopathies remains an unexplored question. We evaluated the histological and functional effects of simultaneous autologous tr...

journal_title：Circulation

authors： Guarita-Souza LC,Carvalho KA,Woitowicz V,Rebelatto C,Senegaglia A,Hansen P,Miyague N,Francisco JC,Olandoski M,Faria-Neto JR,Brofman P

更新日期：2006-07-04 00:00:00