Measurement of cardioversion/defibrillation thresholds in man by a truncated exponential waveform and an apical patch-superior vena caval spring electrode configuration.

abstract：:Patients undergoing carotid endarterectomy were pretreated with low-dose, oral beta carotene to determine whether the carotenoid content of plaque could be increased in vivo. Beta carotene-treated patients had a 50-fold increase in their plaque beta carotene level from 0.066 to 3.3 micrograms beta carotene/g plaque. M...

journal_title：Circulation

authors： Prince MR,LaMuraglia GM,MacNichol EF Jr

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Current consensus statements maintain that endoscopic vein harvesting (EVH) should be standard care in coronary artery bypass graft surgery, but vein quality and clinical outcomes have been questioned. The VICO trial (Vein Integrity and Clinical Outcomes) was designed to assess the impact of different vein h...

journal_title：Circulation

authors： Krishnamoorthy B,Critchley WR,Thompson AJ,Payne K,Morris J,Venkateswaran RV,Caress AL,Fildes JE,Yonan N

更新日期：2017-10-31 00:00:00

abstract：BACKGROUND:Pharmacological ventricular rate control is an acceptable atrial fibrillation (AF) therapy limited by systemic toxicity. We postulate that focal catheter-based drug delivery into the atrioventricular nodal (AVN) region may effectively control ventricular rate during AF without systemic toxicity. This study e...

journal_title：Circulation

authors： Sigg DC,Hiniduma-Lokuge P,Coles JA Jr,Falkner P,Rose R,Urban JF,Ujhelyi MR

更新日期：2006-05-23 00:00:00

abstract：BACKGROUND:In the congenital long-QT syndrome (LQTS), there can be a marked phenotypic heterogeneity. Founder effects, by which many individuals share a mutation identical by descent, represent a powerful tool to further understand the underlying mechanisms and to predict the natural history of mutation-associated effe...

journal_title：Circulation

authors： Brink PA,Crotti L,Corfield V,Goosen A,Durrheim G,Hedley P,Heradien M,Geldenhuys G,Vanoli E,Bacchini S,Spazzolini C,Lundquist AL,Roden DM,George AL Jr,Schwartz PJ

更新日期：2005-10-25 00:00:00

abstract：BACKGROUND:Vascular inflammation and lipid deposition are prominent features of atherosclerotic lesion formation. We have shown previously that the dithiol compound alpha-lipoic acid (LA) exerts antiinflammatory effects by inhibiting tumor necrosis factor-alpha- and lipopolysaccharide-induced endothelial and monocyte a...

journal_title：Circulation

authors： Zhang WJ,Bird KE,McMillen TS,LeBoeuf RC,Hagen TM,Frei B

更新日期：2008-01-22 00:00:00

abstract：BACKGROUND:Despite improvements in management, infective endocarditis remains associated with high mortality and morbidity. We describe temporal changes in the incidence, microbiology, and outcomes of infective endocarditis and the effect of changes in national antibiotic prophylaxis guidelines on incident infective en...

journal_title：Circulation

authors： Shah ASV,McAllister DA,Gallacher P,Astengo F,Rodríguez Pérez JA,Hall J,Lee KK,Bing R,Anand A,Nathwani D,Mills NL,Newby DE,Marwick C,Cruden NL

更新日期：2020-06-23 00:00:00

abstract：:Scanning and transmission electron microscopic studies were made of: 1) 15 glutaraldehyde-treated porcine valvular heterografts that had been implanted in patients for periods of time ranging from 2 days to 76 months; 2) unimplanted, commercially processed porcine aortic valves; and 3) unprocessed porcine aortic valve...

journal_title：Circulation

authors： Ferrans VJ,Spray TL,Billingham ME,Roberts WC

更新日期：1978-09-01 00:00:00

abstract：:Disorders associated with the overproduction or delayed clearance of beta-very low density lipoprotein and low density lipoprotein (LDL) are strikingly related to premature coronary artery disease. There are five recognized classes of LDL-lowering drugs, each acting through different basic mechanisms. The increased pr...

journal_title：Circulation

authors： Levy RI,Troendle AJ,Fattu JM

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Early childhood introduction of nutritional habits aimed at atherosclerosis prevention reduces children's serum total cholesterol concentration, but its effect on vascular endothelial function is unknown. METHODS AND RESULTS:Between 1990 and 1992, we randomized healthy 7-month-old infants (n=1062) to interv...

journal_title：Circulation

authors： Raitakari OT,Rönnemaa T,Järvisalo MJ,Kaitosaari T,Volanen I,Kallio K,Lagström H,Jokinen E,Niinikoski H,Viikari JS,Simell O

更新日期：2005-12-13 00:00:00

abstract：:Subaortic stenosis is well known to complicate the clinical course of patients with single ventricle or univentricular hearts, and we have previously suggested that the development of subaortic stenosis in such patients may be causal to and/or accelerated by previous banding of the main pulmonary trunk. To further def...

journal_title：Circulation

authors： Freedom RM,Benson LN,Smallhorn JF,Williams WG,Trusler GA,Rowe RD

更新日期：1986-04-01 00:00:00

abstract：BACKGROUND:Assessment of systemic right ventricular (RV) function is a key point in the follow-up of patients with transposition of the great arteries (TGA). Current echocardiographic assessment of RV function is at best an estimate, and cardiac magnetic resonance (CMR) is considered the gold standard. However, this te...

journal_title：Circulation

authors： Salehian O,Schwerzmann M,Merchant N,Webb GD,Siu SC,Therrien J

更新日期：2004-11-16 00:00:00

abstract：BACKGROUND:Impaired endothelium-dependent, nitric oxide (NO)-mediated vasodilation may contribute to increased vasomotor tone in patients with heart failure. Whether decreased endothelium-dependent, NO-mediated vasodilation in patients with heart failure is due to decreased synthesis or increased degradation of NO is u...

journal_title：Circulation

authors： Katz SD,Khan T,Zeballos GA,Mathew L,Potharlanka P,Knecht M,Whelan J

更新日期：1999-04-27 00:00:00

abstract：BACKGROUND:Induction of matrix metalloproteinases (MMPs) contributes to adverse remodeling after myocardial infarction (MI). Whether a region- and type-specific distribution of MMPs occurs within the post-MI myocardium remained unknown. METHODS AND RESULTS:Ten sheep were instrumented with a sonomicrometry array to mea...

journal_title：Circulation

authors： Wilson EM,Moainie SL,Baskin JM,Lowry AS,Deschamps AM,Mukherjee R,Guy TS,St John-Sutton MG,Gorman JH 3rd,Edmunds LH Jr,Gorman RC,Spinale FG

更新日期：2003-06-10 00:00:00

abstract：BACKGROUND:Pain triggers a homeostatic alarm reaction to injury. It remains unknown, however, whether nociceptive signaling activated by ischemia is relevant for progenitor cells (PC) release from bone marrow. To this end, we investigated the role of the neuropeptide substance P (SP) and cognate neurokinin 1 (NK1) noci...

journal_title：Circulation

authors： Amadesi S,Reni C,Katare R,Meloni M,Oikawa A,Beltrami AP,Avolio E,Cesselli D,Fortunato O,Spinetti G,Ascione R,Cangiano E,Valgimigli M,Hunt SP,Emanueli C,Madeddu P

更新日期：2012-04-10 00:00:00

abstract：BACKGROUND:The purpose of this study was to compare differential effects of a segment of slow conduction during ventricular tachycardia (VT) due to depression of the action potential and electrical uncoupling. METHODS AND RESULTS:In 33 Langendorff-perfused rabbit hearts, a ring of anisotropic left ventricular subepica...

journal_title：Circulation

authors： Haberl K,Allessie M

更新日期：1999-02-23 00:00:00

abstract：BACKGROUND:It has been suggested that intracellular Ca2+ overload in cardiac myocytes leads to the development of diabetic cardiomyopathy. Troglitazone, an insulin-sensitizing agent, is a promising therapeutic agent for diabetes and has been shown to prevent diabetes-induced myocardial changes. To elucidate the underly...

journal_title：Circulation

authors： Nakajima T,Iwasawa K,Oonuma H,Imuta H,Hazama H,Asano M,Morita T,Nakamura F,Suzuki J,Suzuki S,Kawakami Y,Omata M,Okuda Y

更新日期：1999-06-08 00:00:00

abstract：BACKGROUND:The relationships between childhood lifestyle risk factors and adulthood pulse wave velocity (PWV) have not been reported. We studied whether childhood and adulthood lifestyle risk factors are associated with PWV assessed in adulthood. METHODS AND RESULTS:The study cohort comprised 1622 subjects of the Card...

journal_title：Circulation

authors： Aatola H,Koivistoinen T,Hutri-Kähönen N,Juonala M,Mikkilä V,Lehtimäki T,Viikari JS,Raitakari OT,Kähönen M

更新日期：2010-12-14 00:00:00

abstract：BACKGROUND:Whether catheter ablation (CA) is superior to amiodarone (AMIO) for the treatment of persistent atrial fibrillation (AF) in patients with heart failure is unknown. METHODS AND RESULTS:This was an open-label, randomized, parallel-group, multicenter study. Patients with persistent AF, dual-chamber implantable...

journal_title：Circulation

authors： Di Biase L,Mohanty P,Mohanty S,Santangeli P,Trivedi C,Lakkireddy D,Reddy M,Jais P,Themistoclakis S,Dello Russo A,Casella M,Pelargonio G,Narducci ML,Schweikert R,Neuzil P,Sanchez J,Horton R,Beheiry S,Hongo R,Hao S,

更新日期：2016-04-26 00:00:00

abstract：:The radial artery (RA) is a commonly used conduit for coronary artery bypass grafting, and recent studies have demonstrated that it provides superior long-term patency rates to the saphenous vein in most situations. In addition, the RA is also being used with increasing frequency as the access point for coronary angio...

journal_title：Circulation

authors： Mounsey CA,Mawhinney JA,Werner RS,Taggart DP

更新日期：2016-08-30 00:00:00

abstract：:High frequency notching of the QRS complex is associated with transmural infarction, cardiomyopathies, and ventricular hypertrophy from any cause. The mechanism producing notching is unknown; but the presence of a discrete anatomic lesion is not an essential feature. The hypothesis that notching was produced by activa...

journal_title：Circulation

authors： Vanderark CR,Reynolds EW

更新日期：1975-02-01 00:00:00

abstract：:Systemic, renal and splanchnic hemodynamics, intravascular volume, circulating catecholamine levels and plasma renin activity were compared in 39 patients with borderline hypertension and 28 normotensive subjects, who were less than 5% (n = 42, lean patients) or more than 40% overweight (n = 25, obese patients). Lean ...

journal_title：Circulation

authors： Messerli FH,Ventura HO,Reisin E,Dreslinski GR,Dunn FG,MacPhee AA,Frohlich ED

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND:Angiotensin II (Ang II) plays a critical role in the development of vascular lesions in hypertension, atherosclerosis, and several renal diseases. Because Ang II may contribute to the leukocyte recruitment associated with these pathological states, the aim of the present study was to assess the role of Ang I...

journal_title：Circulation

authors： Piqueras L,Kubes P,Alvarez A,O'Connor E,Issekutz AC,Esplugues JV,Sanz MJ

更新日期：2000-10-24 00:00:00

abstract：:Transthyretin amyloid cardiomyopathy (ATTR-CM) results in a restrictive cardiomyopathy caused by extracellular deposition of transthyretin, normally involved in the transportation of the hormone thyroxine and retinol-binding protein, in the myocardium. Enthusiasm about ATTR-CM has grown as a result of 3 simultaneous a...

journal_title：Circulation

authors： Kittleson MM,Maurer MS,Ambardekar AV,Bullock-Palmer RP,Chang PP,Eisen HJ,Nair AP,Nativi-Nicolau J,Ruberg FL,American Heart Association Heart Failure and Transplantation Committee of the Council on Clinical Cardiology.

更新日期：2020-07-07 00:00:00

abstract：:Coronary artery bypass surgery with or without aneurysmectomy has been used to treat patients with angiographically defined left ventricular aneurysm. To evaluate whether surgery benefits such patients, we analyzed the data from 1131 patients who were enrolled in the registry of the Coronary Artery Surgery Study. Four...

journal_title：Circulation

authors： Faxon DP,Myers WO,McCabe CH,Davis KB,Schaff HV,Wilson JW,Ryan TJ

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:The long-term administration of ACE inhibitors to selected patients with left ventricular dysfunction appears to reduce the incidence of recurrent myocardial infarction (MI) and unstable angina pectoris. The mechanisms responsible for the reduction in ischemic events are unknown, but likely candidates includ...

journal_title：Circulation

authors： Vaughan DE,Rouleau JL,Ridker PM,Arnold JM,Menapace FJ,Pfeffer MA

更新日期：1997-07-15 00:00:00

abstract：:This review defines the substantial pediatric morbidity from tobacco use, including health effects on the cardiovascular system, the respiratory system, the fetus and newborn, and risk-taking behaviors of adolescents. More recent research suggests effects may extend to other areas, including reports that cigarette smo...

journal_title：Circulation

authors：

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Combining 2 signals of cardiomyocyte injury, cardiac troponin I (cTnI) and T (cTnT), might overcome some individual pathophysiological and analytical limitations and thereby increase diagnostic accuracy for acute myocardial infarction with a single blood draw. We aimed to evaluate the diagnostic performance ...

journal_title：Circulation

authors： van der Linden N,Wildi K,Twerenbold R,Pickering JW,Than M,Cullen L,Greenslade J,Parsonage W,Nestelberger T,Boeddinghaus J,Badertscher P,Rubini Giménez M,Klinkenberg LJJ,Bekers O,Schöni A,Keller DI,Sabti Z,Puelacher C,

更新日期：2018-09-04 00:00:00

abstract：:Retrograde coronary artery flow was observed angiographically in 43 patients with aortic stenosis and/or regurgitation. In the 24 patients with pure or predominant aortic stenosis, retrograde flow was seen in all 24 during end-systole. In the eight patients with pure aortic regurgitation, retrograde flow was seen main...

journal_title：Circulation

authors： Carroll RJ,Falsetti HL

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND:Inhibition of dopamine beta-hydroxylase (DBH) results in a decrease in norepinephrine synthesis. The present study was a randomized, blinded, placebo-controlled investigation of the long-term effects of therapy with the DBH inhibitor nepicastat (NCT) on the progression of left ventricular (LV) dysfunction an...

journal_title：Circulation

authors： Sabbah HN,Stanley WC,Sharov VG,Mishima T,Tanimura M,Benedict CR,Hegde S,Goldstein S

更新日期：2000-10-17 00:00:00

abstract：BACKGROUND:Interaction of complement with endothelial cells (ECs) underlies the development of inflammation and coagulation in disease. Assembly of the membrane attack complex (MAC) of complement on EC membrane, like stimulation with cytokines, upregulates tissue factor and cyclooxygenase-2 but does so via the intermed...

journal_title：Circulation

authors： Saadi S,Holzknecht RA,Patte CP,Platt JL

更新日期：2000-04-18 00:00:00