Pulmonary ventilation/perfusion defects induced by epinephrine during cardiopulmonary resuscitation.

abstract：BACKGROUND:Few data are available on the long-term outcome of patients who undergo laser-assisted balloon angioplasty for recanalization of occluded peripheral arteries. Because the cost of laser angioplasty is high, the value of the method should be carefully analyzed before it can be considered a routine method for r...

journal_title：Circulation

authors： Geschwind HJ,Aptecar E,Boussignac G,Dubois-Randé JL,Zelinsky R,Poirot G,Tomaru T

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:Molecular imaging of thrombus within fissures of vulnerable atherosclerotic plaques requires sensitive detection of a robust thrombus-specific contrast agent. In this study, we report the development and characterization of a novel ligand-targeted paramagnetic molecular imaging agent with high avidity for fi...

journal_title：Circulation

authors： Flacke S,Fischer S,Scott MJ,Fuhrhop RJ,Allen JS,McLean M,Winter P,Sicard GA,Gaffney PJ,Wickline SA,Lanza GM

更新日期：2001-09-11 00:00:00

abstract：BACKGROUND:Human cardiac troponin I is known to be phosphorylated at multiple amino acid residues by several kinases. Advances in mass spectrometry allow sensitive detection of known and novel phosphorylation sites and measurement of the level of phosphorylation simultaneously at each site in myocardial samples. METHO...

journal_title：Circulation

authors： Zhang P,Kirk JA,Ji W,dos Remedios CG,Kass DA,Van Eyk JE,Murphy AM

更新日期：2012-10-09 00:00:00

abstract：:Systolic time intervals, stroke volume, cardiac output and (dZ/dt)/RZ index were serially estimated in 51 normal healthy volunteers at sea level, for ten days after air induction to 3658 m altitude and on return to sea level. The subjects were divided into three groups and were administered a diuretic, beta methyldigo...

journal_title：Circulation

authors： Balasubramanian V,Behl A,Das GS,Wadhwa AK,Mathew OP,Hoon RS

更新日期：1978-06-01 00:00:00

abstract：:Over the last 20 years, operative mortality has decreased and late survival has improved for patients with chronic stable angina who have coronary artery bypass surgery. However, this favorable trend may not continue because the operation is now extended to elderly and high-risk patients. The most powerful predictors ...

journal_title：Circulation

authors： Gersh BJ,Califf RM,Loop FD,Akins CW,Pryor DB,Takaro TC

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:NO has been advocated as an adjunct to cardioplegia solutions. However, NO undergoes a rapid biradical reaction with superoxide anions to produce peroxynitrite (ONOO(-)). ONOO(-) in crystalloid cardioplegia solution induces injury to coronary endothelium and to systolic function after cardioplegia and reperf...

journal_title：Circulation

authors： Nakamura M,Thourani VH,Ronson RS,Velez DA,Ma XL,Katzmark S,Robinson J,Schmarkey LS,Zhao ZQ,Wang NP,Guyton RA,Vinten-Johansen J

更新日期：2000-11-07 00:00:00

abstract：BACKGROUND:Angiotensin-converting enzyme (ACE) inhibition potentiates the tissue-type plasminogen activator (t-PA) response to exogenous bradykinin. This study tested the hypothesis that ACE inhibition increases endothelial t-PA release through endogenous bradykinin. METHODS AND RESULTS:We measured the effect of intra...

journal_title：Circulation

authors： Pretorius M,Rosenbaum D,Vaughan DE,Brown NJ

更新日期：2003-02-04 00:00:00

abstract：BACKGROUND:We sought to separately examine the effects of either weight loss or diets varying in protein content and glycemic index without further changes in body weight on cardiovascular risk factors within the Diet, Obesity, and Genes study (DiOGenes). METHODS AND RESULTS:DiOGenes is a pan-European controlled dieta...

journal_title：Circulation

authors： Gögebakan O,Kohl A,Osterhoff MA,van Baak MA,Jebb SA,Papadaki A,Martinez JA,Handjieva-Darlenska T,Hlavaty P,Weickert MO,Holst C,Saris WH,Astrup A,Pfeiffer AF,DiOGenes.

更新日期：2011-12-20 00:00:00

abstract：BACKGROUND:Clopidogrel is administered to prevent stent thrombosis; however, the uniformity of platelet inhibition after treatment and the influence of pretreatment reactivity on drug response have not been described. METHODS AND RESULTS:Platelet aggregation (5 and 20 micromol/L ADP), the activation of glycoprotein II...

journal_title：Circulation

authors： Gurbel PA,Bliden KP,Hiatt BL,O'Connor CM

更新日期：2003-06-17 00:00:00

abstract：BACKGROUND:Pulmonary hypertension induced by chronic hypoxia is characterized by thickening of pulmonary artery walls, elevated pulmonary vascular resistance, and right-heart failure. Prostacyclin analogues reduce pulmonary pressures in this condition; raising the possibility that cycloxygenase-2 (COX-2) modulates the ...

journal_title：Circulation

authors： Pidgeon GP,Tamosiuniene R,Chen G,Leonard I,Belton O,Bradford A,Fitzgerald DJ

更新日期：2004-10-26 00:00:00

abstract：BACKGROUND:Current intravascular ultrasound (IVUS) catheters provide transverse imaging at the level of the ultrasound transducer. This limits imaging to large-diameter segments without critical atherosclerotic narrowings. We have developed a prototype 20-MHz forward-viewing IVUS catheter that provides two-dimensional ...

journal_title：Circulation

authors： Ng KH,Evans JL,Vonesh MJ,Meyers SN,Mills TA,Kane BJ,Aldrich WN,Jang YT,Yock PG,Rold MD

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Preclinical systolic or diastolic dysfunction is associated with increased morbidity and mortality. We postulated that plasma brain natriuretic peptide (BNP) might serve as a biomarker for preclinical ventricular dysfunction (PCVD) but that the discriminatory values for BNP may vary with age and sex. METHOD...

journal_title：Circulation

authors： Redfield MM,Rodeheffer RJ,Jacobsen SJ,Mahoney DW,Bailey KR,Burnett JC Jr

更新日期：2004-06-29 00:00:00

abstract：:Predictability of prognosis was analyzed in 630 patients who were alive 30 days after valve replacement (1965-1986) for aortic stenosis. Follow-up totaled 4,072 patient-years. During the operative periods of 1965-1971 (n = 62), 1972-1976 (n = 164), 1977-1981 (n = 158), and 1982-1986 (n = 246), decreases in cardiothora...

journal_title：Circulation

authors： Lund O

更新日期：1990-07-01 00:00:00

abstract：:This study examined quantitative regional myocardial perfusion (RMP) measured by the washout of 133Xe at rest and after an isoproterenol challenge in 50 patients (group I) studied 8 to 14 days after they underwent saphenous vein bypass grafting to the left coronary artery, and compared this with RMP measured in the na...

journal_title：Circulation

authors： Schmidt DH,Blau FM,Hendrix LJ,Kamath ML,Ray G

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:Long-term survival after acute kidney injury (AKI) is poorly studied. We report the relationship between long-term mortality and AKI with small changes in serum creatinine during hospitalization after various cardiothoracic surgery procedures. METHODS AND RESULTS:This was a retrospective study of 2973 patie...

journal_title：Circulation

authors： Hobson CE,Yavas S,Segal MS,Schold JD,Tribble CG,Layon AJ,Bihorac A

更新日期：2009-05-12 00:00:00

abstract：BACKGROUND:Recently, it was reported that the degree of microvascular injury and left ventricular functional recovery during the chronic period can be predicted after treatment of the infarct-related artery based on the coronary flow velocity (CFV) pattern assessed using a Doppler guidewire. The aim of this prospective...

journal_title：Circulation

authors： Yamamuro A,Akasaka T,Tamita K,Yamabe K,Katayama M,Takagi T,Morioka S

更新日期：2002-12-10 00:00:00

abstract：:Separate effects of perfusion hypothermia, potassium arrest, and procaine arrest were studied in 150 hearts using the isolated rat heart preparation. Aortic flow rate (AFR), coronary flow rate (CFR), and heart rate (HR) were measured before and after ischemic periods of 90 to 300 min. Prior to the ischemic period, the...

journal_title：Circulation

authors： Harlan BJ,Ross D,Macmanus Q,Knight R,Luber J,Starr A

更新日期：1978-09-01 00:00:00

abstract：:Cardiovascular disease is the number one cause of death for women in the United States. Of the 1.3 million active duty service members, 16.3% are currently women, and the number of women veterans is expected to increase. Women veterans have higher rates of cardiovascular disease than civilian women and present a uniqu...

journal_title：Circulation

authors： Han JK,Yano EM,Watson KE,Ebrahimi R

更新日期：2019-02-19 00:00:00

abstract：:The effect of potassium ion (K+) depletion on postmyocardial infarction ventricular arrhythmias was investigated in 32 dogs: 12 control animals, 10 animals that ate a diet extremely low in K+ for 15 days, and 10 others that, in addition to dietary K+ deprivation, received 50 mg of hydrochlorothiazide four times. The e...

journal_title：Circulation

authors： Garan H,McGovern BA,Canzanello VJ,McCauley J,Bodvarsson M,Harrington JT,Madias NE,Newell JB,Ruskin JN

更新日期：1988-03-01 00:00:00

abstract：:The electrophysiologic effects of amiodarone were examined in 13 dogs that received 30 g amiodarone orally during 3 weeks and compared with 13 control dogs that did not receive amiodarone. Longitudinal and transverse epicardial conduction velocities were estimated with a square array of 64 closely spaced electrodes an...

journal_title：Circulation

authors： Anderson KP,Walker R,Dustman T,Lux RL,Ershler PR,Kates RE,Urie PM

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND:The Na+-H+ exchanger figures prominently in cardiac ischemia-reperfusion injury. Several experimental and clinical studies have demonstrated a cardioprotective effect of Na+-H+ exchanger inhibition; however, the precise mechanisms have not been established. METHODS AND RESULTS:We examined the effects of car...

journal_title：Circulation

authors： Teshima Y,Akao M,Jones SP,Marbán E

更新日期：2003-11-04 00:00:00

abstract：:The electrophysiologic mechanisms for the initiation and termination of re-entrant ventricular arrhythmias (RVA) were critically analyzed in dogs 3-7 days following ligation of the anterior descending coronary artery, utilizing direct recordings of the re-entrant pathway (RP) from the epicardial surface of the infarct...

journal_title：Circulation

authors： El-Sherif N,Hope RR,Scherlag BJ,Lazzara R

更新日期：1977-05-01 00:00:00

abstract：:The pathogenesis of paradoxical hypertension after resection of coarctation of the aorta was investigated by comparing the course of seven children undergoing repair of coarctation with five acyanotic children undergoing elective cardiovascular surgery. During the first 24 hours after surgery, all coarctation patients...

journal_title：Circulation

authors： Rocchini AP,Rosenthal A,Barger AC,Castaneda AR,Nadas AS

更新日期：1976-09-01 00:00:00

abstract：:This study was conducted in 46 patients with cardiac thrombi, 15 patients with atrial myxomas, and 32 patients with other cardiac or paracardiac tumors. Diagnoses were subsequently proven by surgery, autopsy, computed tomography, magnetic resonance imaging, or angiography in all patients. All patients underwent precor...

journal_title：Circulation

authors： Mügge A,Daniel WG,Haverich A,Lichtlen PR

更新日期：1991-01-01 00:00:00

abstract：:An asymptomatic 14-year-old male was found at cardiac catheterization to have a coronary artery fistula involving a vessel originating from the left main coronary artery and terminating in the right heart. Chest X-ray and electrocardiogram were within normal limits and shunt flow was too small to be detected by oximet...

journal_title：Circulation

authors： Shubrooks SJ Jr,Naggar CZ

更新日期：1978-01-01 00:00:00

abstract：:Platelet function can be assessed by various techniques in vitro or in vivo, but methodological problems in the field are considerable. By use of the conventional in vitro technique (Born aggregometry), it has been shown that sympathoadrenal activation in vivo (e.g., mental stress, epinephrine infusions, exercise, and...

journal_title：Circulation

authors： Hjemdahl P,Larsson PT,Wallén NH

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Cardiovascular disease is the leading cause of death for both men and women in the United States and the world. A profound pattern exists in the time of day at which the death occurs; it is in the morning, when the endothelium is most vulnerable and blood pressure surges, that stroke and heart attack most fr...

journal_title：Circulation

authors： Anea CB,Zhang M,Stepp DW,Simkins GB,Reed G,Fulton DJ,Rudic RD

更新日期：2009-03-24 00:00:00

abstract：:We quantitated the growth patterns of the normal fetal heart and the right and left ventricles from postmortem hearts obtained from 55 spontaneously aborted human fetuses from the completion of cardiogenesis to term. Fetal gestational age was assessed by menstrual history of the mother, crown-rump length, head circumf...

journal_title：Circulation

authors： St John Sutton MG,Raichlen JS,Reichek N,Huff DS

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:We examined the associations of a range of parental and early life characteristics with systolic blood pressure at 5 years of age. METHODS AND RESULTS:Information from 3864 children who were followed up prospectively from their mother's first antenatal clinic assessment was used. Maternal age, body mass ind...

journal_title：Circulation

authors： Lawlor DA,Najman JM,Sterne J,Williams GM,Ebrahim S,Davey Smith G

更新日期：2004-10-19 00:00:00

abstract：BACKGROUND:Epidemiological findings suggest an association between low-for-age birth weight and the risk to develop coronary heart diseases in adulthood. During pregnancy, an imbalance between fetal demands and supply may result in permanent alterations of neuroendocrine development in the fetus. We evaluated whether c...

journal_title：Circulation

authors： Ruijtenbeek K,le Noble FA,Janssen GM,Kessels CG,Fazzi GE,Blanco CE,De Mey JG

更新日期：2000-12-05 00:00:00