Abstract:
:The results of coronary bypass 5-10 years after operation at the Baylor College of Medicine are reported. The late results demonstrate that good relief of symptoms of angina pectoris persisted in 89% of patients at 10 years of follow-up. An overall annual attrition rate of 3% has been fairly constant through 10 years of follow-up. Graft patency has declined at a rate of about 1% per year after the first year, with patency rates in the 5-10-year interval approaching 80%. Pathologic changes in the vein grafts of intimal proliferation or atherosclerosis appear to pose a limited threat to long-term patency. Although derived from an early experience in which perioperative mortality was relatively high and revascularization incomplete, these favorable long-term results are encouraging.
journal_name
Circulationjournal_title
Circulationauthors
Lawrie GM,Morris GC Jrdoi
10.1161/01.cir.65.7.43subject
Has Abstractpub_date
1982-06-01 00:00:00pages
43-8issue
7 Pt 2eissn
0009-7322issn
1524-4539journal_volume
65pub_type
杂志文章相关文献
CIRCULATION文献大全abstract:BACKGROUND:Cardiac transplantation and chronic myocardial infarction interrupt vagal afferent nerve fibers, which originate mainly from the ventricles. Marked abnormalities of reflexes mediated by cardiopulmonary receptors with vagal afferent fibers have been demonstrated after both cardiac transplantation and chronic ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.90.4.2015
更新日期:1994-10-01 00:00:00
abstract::We examined the cardiopulmonary effects of maximum bicycle ergometer exercise in seven patients with implanted Intermedics Nova MR pacemakers for three types of pacing in a randomized sequence: VVI or AAI at 70 beats/min (SSI 70), rate-adaptive temperature-controlled pacing with the implanted Nova MR, and rate-adaptiv...
journal_title:Circulation
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1988-11-01 00:00:00
abstract::Paroxysmal supraventricular tachycardia (PSVT) is commonly caused by reentry within the atrioventricular (AV) node. This arrhythmia was abolished by operative dissection of the AV junction in a patient with disabling tachycardia that was not controlled by drugs. The operation was intended to create complete AV block, ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.60.2.440
更新日期:1979-08-01 00:00:00
abstract::Total body surface maps from 15 subjects with left bundle branch block and normal axis (LBBB-NA) and 10 subjects with left bundle branch block and left axis (LBBB-LA) were analyzed and compared with maps from normal subjects. In 19 of the 25 subjects with LBBB, the timing of early upper sternal positivity was similar ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.67.3.660
更新日期:1983-03-01 00:00:00
abstract::To investigate whether ergonovine acts directly on coronary arteries or via remote neurohumoral reflexes, we administered small titrated increments of intracoronary ergonovine up to a maximum cumulative dose of 50 micrograms to 15 patients. In six patients with variant angina (group 1), ischemic electrocardiographic S...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.75.3.577
更新日期:1987-03-01 00:00:00
abstract::Long-term tocainide therapy has been evaluated in 17 patients with ventricular arrhythmias. Ventricular tachycardia and/or fibrillation was recurrent and sustained in nine patients, and symptomatic but unsustained in three others. Five patients had frequent but only mildly symptomatic ventricular irritability. In all ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.57.5.1008
更新日期:1978-05-01 00:00:00
abstract::Prenalterol, a beta-adrenergic agonist, was given to nine patients with angiographically proved coronary artery disease. Subjects were studied during chronic beta-adrenergic blockade. The adequacy of blockade was assessed by the exercise heart rate response and by plasma concentrations of blocking agents. After increm...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.64.6.1135
更新日期:1981-12-01 00:00:00
abstract::Survival rates were determined for a group of 598 patients in whom severe coronary disease was demonstrated by arteriography; initially they were treated medically and were followed-up for 15 years. Deaths due to noncoronary causes were uncommon (5% of total) in the first 5 year period but were frequent (36%) in the t...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.68.5.986
更新日期:1983-11-01 00:00:00
abstract:BACKGROUND:Autosomal dominant hypercholesterolemia (ADH) is characterized by elevated low-density lipoprotein cholesterol levels and premature cardiovascular disease. Mutations in the genes encoding for low-density lipoprotein receptor (LDLR), apolipoprotein B (APOB), and proprotein convertase subtilisin/kexin 9 (PCSK9...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.110.979450
更新日期:2011-03-22 00:00:00
abstract::The clinical significance of perioperative myocardial infarction (MI) after coronary artery bypass surgery is not known. Therefore, strategies for the risk stratification of these patients do not exist. This study was undertaken to define the effect of perioperative MI on prognosis after discharge from the hospital an...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.82.3.903
更新日期:1990-09-01 00:00:00
abstract:BACKGROUND:The role of intracellular calcium (Ca(i)) in defibrillation and vulnerability is unclear. METHODS AND RESULTS:We simultaneously mapped epicardial membrane potential and Ca(i) during shock on T-wave episodes (n=104) and attempted defibrillation episodes (n=173) in 17 Langendorff-perfused rabbit ventricles. U...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.106.630509
更新日期:2006-12-12 00:00:00
abstract::One hundred consecutive men with a normal ECG at rest had a maximal treadmill test using 14 leads during and post-exercise. Coronary arteriography performed the following day revealed coronary stenoses greater than or equal to 70% in 66 patients. Test results obtained from a V5 lead were compared to different lead com...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.57.1.71
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND:Radiofrequency ablation of the atrioventricular node and permanent pacing are used for symptomatic relief in patients with medically refractory atrial fibrillation. In this study, meta-analysis was used to clarify clinical outcomes and survival after ablation and pacing therapy using data from the published ...
journal_title:Circulation
pub_type: 杂志文章,meta分析
doi:10.1161/01.cir.101.10.1138
更新日期:2000-03-14 00:00:00
abstract:BACKGROUND:Adriamycin (ADR) is an anticancer drug known to cause severe cardiac toxicity by generating free radicals. We investigated the role of a redox-regulating molecule, thioredoxin-1 (TRX1), in ADR-induced cardiotoxicity. METHODS AND RESULTS:The in vitro study showed that TRX1 was dose-dependently increased conc...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.0000027817.55925.b4
更新日期:2002-09-10 00:00:00
abstract:BACKGROUND:The hypoxia-inducible transcription factor (HIF) subunits are destabilized via the O(2)-dependent prolyl hydroxylase domain proteins (PHD1, PHD2, and PHD3). We investigated whether inhibition of PHDs via upregulating HIF might promote postischemic neovascularization. METHODS AND RESULTS:Mice with right femo...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.108.813303
更新日期:2009-07-07 00:00:00
abstract::A clinical study was conducted to evaluate the efficacy and safety of percutaneous coronary excimer laser angioplasty in 60 patients with coronary artery disease. Forty-nine patients had stable exertional angina, and 11 patients had unstable angina despite medical therapy. A novel 1.4-mm diameter catheter with 20 quar...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.81.6.1849
更新日期:1990-06-01 00:00:00
abstract::Common conditions predisposing to atherosclerosis, such as hypercholesterolemia, hypertension, diabetes, and smoking, are associated with endothelial dysfunction. Endothelial function has largely been assessed as endothelium-dependent vasomotion, at least in part based on the assumption that impaired endothelium-depen...
journal_title:Circulation
pub_type: 杂志文章,评审
doi:10.1161/01.CIR.0000129501.88485.1f
更新日期:2004-06-01 00:00:00
abstract::Defibrillation/cardioversion thresholds were measured in 33 patients undergoing defibrillator implants. Each patient had a 12 cm2 patch placed near the left ventricular apex via a thoracotomy and a 10 cm2 spring lead placed pervenously at the right atrial-superior vena caval junction. Ventricular tachycardia of stable...
journal_title:Circulation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1161/01.cir.69.4.766
更新日期:1984-04-01 00:00:00
abstract:BACKGROUND:Mitral regurgitation (MR) due to mitral valve prolapse (MVP) is often treatable by surgical repair. However, the very long-term (>10-year) durability of repair in both anterior leaflet prolapse (AL-MVP) and posterior leaflet prolapse (PL-MVP) is unknown. METHODS AND RESULTS:In 917 patients (aged 65+/-13 yea...
journal_title:Circulation
pub_type: 临床试验,杂志文章
doi:10.1161/hc37t1.094903
更新日期:2001-09-18 00:00:00
abstract:BACKGROUND:The Na(+)/Ca(2+) exchange (NCX) extrudes Ca(2+) from cardiac myocytes, but it can also mediate Ca(2+) influx, load the sarcoplasmic reticulum with Ca(2+), and trigger Ca(2+) release from the sarcoplasmic reticulum. In ischemia/reperfusion or digitalis toxicity, increased levels of intracellular [Na(+)] ([Na(...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.101.12.1441
更新日期:2000-03-28 00:00:00
abstract:BACKGROUND:The reason for the delay in onset of the electrophysiological effects and antiarrhythmic efficacy of amiodarone is not clear. The relation between the development of the electrophysiological effects of amiodarone and its myocardial concentration is unknown. We therefore examined the time course of developmen...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.91.2.451
更新日期:1995-01-15 00:00:00
abstract::Atherosclerotic coronary artery disease is the major cause of late cardiac transplant failure secondary to silent ischemia and infarction. To increase the longevity of cardiac homografts, we performed percutaneous transluminal coronary angioplasty (PTCA) in five male patients (aged 45 +/- 7 years, mean +/- SEM); 17 le...
journal_title:Circulation
pub_type: 杂志文章
doi:
更新日期:1988-11-01 00:00:00
abstract:BACKGROUND:Long-term rapid atrial pacing may result in atrial fibrillation (AF) in dogs. Whether there is histological evidence for neural remodeling is unclear. METHOD AND RESULTS:We performed rapid right atrial pacing in 6 dogs for 111+/-76 days to induce sustained AF. Tissues from 6 healthy dogs were used as contro...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.103.1.22
更新日期:2001-01-02 00:00:00
abstract:BACKGROUND:Experimental models suggest that brain natriuretic peptide (BNP) can modify left ventricular diastolic performance. The aim of this study was to evaluate the effects of BNP on resting and exercise hemodynamics and neurohormones in patients with isolated diastolic heart failure. METHODS AND RESULTS:Six patie...
journal_title:Circulation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1161/01.cir.93.11.2037
更新日期:1996-06-01 00:00:00
abstract:BACKGROUND:Defining the arrhythmogenic substrate is essential for successful ablation of scar-related ventricular tachycardia. The visual characteristics of endocardial ischemic scar have not been described in vivo. The goal of this study was (1) to quantify the visual characteristics of normal tissue, scar border zone...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.112.112540
更新日期:2012-10-23 00:00:00
abstract::Aortic root motion was studied in 24 normal volunteers at rest and during the Valsalva maneuver, isometric exercise, and amyl nitrite inhalation. In addition root motion was correlated with the stroke volumes determined at cardiac catheterization in 24 patients. The root has distinct systolic movement, the amplitude a...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.53.6.947
更新日期:1976-06-01 00:00:00
abstract:BACKGROUND:Recent data suggest that the Berlin Heart EXCOR Pediatric ventricular assist device is superior to extracorporeal membrane oxygenation for bridge to heart transplantation. Published data are limited to 1 in 4 children who received the device as part of the US clinical trial. We analyzed outcomes for all US c...
journal_title:Circulation
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1161/CIRCULATIONAHA.112.000685
更新日期:2013-04-23 00:00:00
abstract:BACKGROUND:Automatic implantable cardioverter-defibrillator therapy is considered the only effective treatment for high-risk patients with Brugada syndrome. Quinidine depresses I(to) current, which may play an important role in the arrhythmogenesis of this disease. METHODS AND RESULTS:The effects of quinidine bisulfat...
journal_title:Circulation
pub_type: 杂志文章,评审
doi:10.1161/01.CIR.0000143159.30585.90
更新日期:2004-09-28 00:00:00
abstract::This study was conducted in 46 patients with cardiac thrombi, 15 patients with atrial myxomas, and 32 patients with other cardiac or paracardiac tumors. Diagnoses were subsequently proven by surgery, autopsy, computed tomography, magnetic resonance imaging, or angiography in all patients. All patients underwent precor...
journal_title:Circulation
pub_type: 临床试验,杂志文章
doi:10.1161/01.cir.83.1.70
更新日期:1991-01-01 00:00:00
abstract::We studied 14 patients to determine whether sustained-release diltiazem is a satisfactory long-term substitute for the combination of propranolol plus hydrochlorothiazide (HCTZ), control phase, in the treatment of systemic hypertension with coexisting chronic stable angina pectoris. All patients had either one- or two...
journal_title:Circulation
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00